Characterisation of furoxancarbonitriles as a new class of vasodilators

Arzneimittel-Forschung/Drug Research

Volumn 48, Issue 3, 1998, Pages 212-218

  Gasco, André A Marcello ^a,b   Boschi, Donatella ^a,b   Stilo, Antonella Di ^a,b   Medana, Claudio ^a,b   Gasco, Alberto ^a,b   Martorana, Piero Antonio ^a,b   Schönafinger, Karl ^a,b  

^a UNIVERSITY OF TURIN   (Italy)

^b SANOFI   (France)

Author keywords

Furoxan derivatives; Furoxancarbonitriles, synthesis, vasodilation; NO donors; Vasodilators

Indexed keywords

CYANIDE; FUROXANCARBONITRILE; NITRILE; NITROPRUSSIDE SODIUM; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ARTICLE; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; DRUG POTENCY; DRUG SYNTHESIS; MALE; NONHUMAN; SWINE;

ANIMALS; AORTA, THORACIC; HEMODYNAMIC PROCESSES; INTUBATION, GASTROINTESTINAL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRILES; OXADIAZOLES; RATS; RATS, WISTAR; SWINE; VASODILATOR AGENTS;

EID: 0031942809     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Gasco, A., Boulton, J., Adv. Heterocycl. Chem. 29, 251 (1981)
2. Ghigo, D., Heller, R., Calvino, R. et al., Biochem. Pharmacol. 43, 1281 (1992)
3. Feelisch, M., Schönafinger, K., Noack, E., Biochem. Pharmacol. 44, 1149(1992)
4. Ferioli, R., Folco, G. C, Ferretti, C. et al., Br. J. Pharmacol. 114, 816 (1995), and references therein.
5. Sorba, G., Medana, G, Fruttero, R. et al., J. Med. Chem. 40, 463 (1997). The équations (1) and (2) of the paper are incorrectly reported. See errata corrige., J. Med. Chem. 40, 2288 (1997)
6. Fruttero, R., Boschi, D., Di Stilo A. et al., J. Med. Chem. 38, 4944 (1995)
7. Di Stilo, A., Cena, C., Gasco, A. M. et al., Bioorg. Med. Chem. Lett. 6, 2607 (1997)
8. Fruttero, R., Ferrarotti, B., Serafino, A. et al., Liebigs Ann. Chem. 335 (1990)
9. Gasco, A. M., Cena, C., Di Stilo, A. et al., Helv. Chim. Acta 79, 1803 (1996)
10. Noack, E., Kubitzek, D., Kojda, G., Neuroprotocols l, 133 (1992)
11. Bohn, H., Brendel, J., Martorana, P. A. et al., Br. J. Pharmacol. 114, 1605 (1995)
12. Chatterjee, K., Palmer, W. W., Ann. Rev. Pharmacol. Toxicol. 20, 475 (1980)
13. Bohn, H., Martorana, P. A., Schönafinger, K., Eur. J. Pharmacol. 220, 71 (1992)
14. [14) Yamada, H., Yoneyama, F., Satoh, K. et al., Eur. J. Pharmacol. 205, 81 (1991)
15. Wang, J., Zhao, G., Shen, W. et al., J. Cardiovasc. Pharmacol. 22 (Suppl. 7), S51 (1993)