Characterization of the inflammatory infiltrate in autoimmune cholangitis. A morphological and immunhistochemical study

Virchows Archiv

Volumn 432, Issue 3, 1998, Pages 217-222

  Kaserer, K ^a   Exner, M ^a   Mosberger, I ^a   Penner, E ^a   Wrba, F ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Autoimmune diseases; Cholangitis; Immunohistochemistry; T lymphocyte subsets

Indexed keywords

ANTIBODY; CD3 ANTIGEN; CD56 ANTIGEN; CD57 ANTIGEN; CD8 ANTIGEN; GRANZYME B; MONOCLONAL ANTIBODY CD3; OKT 8;

ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; BILE DUCT; CHOLANGITIS; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; LIVER BIOPSY; MORPHOLOGY; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; AGED; ANTIGENS, SURFACE; AUTOIMMUNE DISEASES; CELL MOVEMENT; CHOLANGITIS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CIRRHOSIS, BILIARY; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED; SJOGREN'S SYNDROME;

EID: 0031942516     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050158     Document Type: Article

References (21)

1. Ben-Ari Z, Dhillon AP, Sherlock S (1993) Autoimmune cholangioputhy: part of the spectrum of autoimmune chronic active hepatitis. Hepatology 18:10-15
2. Brunner G, Klinge O (1987) Ein der chronisch nicht destruierenden eitrigen Cholangitis ähnliches Bild mit Antikörpern (Immuncholangitis). Dtsch Med Wochenschr 112:1454-1458
3. Colombato LA, Alvarez F, Côte J, Huet PM (1994) Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis. Gastroenterology 107:1839-1843
4. Czaja AJ (1996) The variant forms of autoimmue hepatitis. Ann Intern Med 125:588-598
5. Dienes HP (1988) Autoimmune hepatitis - new aspects of histopathology, fine structure and immunohistochemistry. Zentralbl Allgem Pathol Anat 134:143-151
6. Feldmann M (1992) Autoimmunization. In: McGee JO, Isaacson PG, Wright NA (ed) Oxford textbook of pathology, vol 1. Oxford University Press, Oxford, pp 297-306
7. Goodman ZD, McNally PR, Davis DR, Ishak KG (1995) Autoimmune cholangitis: a variant of primary biliary cirrhosis. Clinicopalhologic and serologic correlations in 200 cases. Dig Dis Sci 40:1232-1242
8. Heusel JW, Wesselschmidt RL, Shresta S, Russel JH, Ley TJ (1994) Cytotoxic lymphocytes require granzyme B for rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76:977-987
9. Krams SM, Van De Water J, Coppel RL, Esquivel C, Roberts J, Ansari A, Gershwin ME (1990) Analysis of hepatic T lymphocytes and immunoglobulin deposits in patients with primary biliary cirrhosis. Heputology 12:306-313
10. Lacerda MA, Ludwig J, Dickson ER, Jorgensen RA, Lindor KD (1995) Antimitochondrial antibody - negative primary biliary cirrhosis. Am J Gastroenterol 90:247-249
11. Lindenborn-Fotinos J, Baum H, Berg PA (1985) Mitochondrial antibodies in primary biliary cirrhosis: species and non-species-specific determinants of M2 antigen. Hepatology:763-769
12. Ludwig J (1993) The nomenclature of chronic active hepatitis: an obituary. Gastroenterology 105:274-278
13. Michieletti P, Wanless IR, Katz, A, Scheuer PJ, Yeaman SJ, Bassendine MF, Palmer JM, Heathcote EJ (1994) Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis. Gut 35:260-265
14. Mosnier JF, Degott C, Marcellin P, Henin D, Erlinger S, Benhamou JP (1993) The intraportal lymphoid nodule and its environment in chronic active hepatitis C: an immunhistochemical study. Heputology 17:366-371
15. Nakanuma Y (1993) Distribution of B lymphocytes in nonsuppurative cholangitis in primary biliary cirrhosis. Hepatology 18:570-575
16. Nakanuma Y, Ohta G (1979) Histometric and serial section observations of the intrahepatic bile ducts in primary biliary cirrhosis. Gastroenterology 76:1326-1332
17. Scheuer PJ (1967) Primary biliary cirrhosis. Proc R Soc Med 60:1257-1260
18. Taylor SL, Dean PJ, Riely CA (1994) Primary autoimmune cholangitis: an alternative to antimitochondrial antibody negative primary biliary cirrhosis. Am J Surg Pathol 18:91-99
19. Ueno Y, Phillips JO, Ludwig J, Lichtman SN, LaRusso NF (1996) Development and characterisation of a rodent model of immune mediated eholangitis. Proc Natl Acad Sci 93:216-220
20. Woolfe GM, Vierling JM (1993) Disappearing intrahepatic bile ducts: The syndromes and their mechanisms. Sem Liv Dis 13:261-275
21. Yamada G, Ichinosuke H, Tobe K, Mizuno M, Nishihara T, Kobayashi T, Nagashima H (1986) Ultrastructural immunocytochemical analysis of lymphocytes infiltrating bile duct epithelia in primary biliary cirrhosis. Hepatolgoy 6:385-391