Blood-brain barrier penetration of 3-aminopropyl-n-butylphosphinic acid (CGP 36742) in rat brain by microdialysis/mass spectrometry

Journal of Mass Spectrometry

Volumn 33, Issue 3, 1998, Pages 281-287

  Andrén, Per E ^a   Emmett, Mark R ^a   DaGue, Beverly B ^a   Steulet, Anne Françoise ^b   Waldmeier, Peter ^b   Caprioli, Richard M ^a,c  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3 aminopropyl n butylphosphinic acid; CGP 36742; GABA antagonist; Mass spectrometry; Microdialysis; Pharmacokinetics

Indexed keywords

3 AMINOPROPYLBUTYLPHOSPHINIC ACID;

ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BLOOD BRAIN BARRIER; BRAIN TISSUE; DRUG PENETRATION; ENZYME SPECIFICITY; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CALIBRATION; CEREBRAL VENTRICLES; ELECTROCHEMISTRY; GABA ANTAGONISTS; MALE; MASS SPECTROMETRY; MICRODIALYSIS; ORGANOPHOSPHORUS COMPOUNDS; PREFRONTAL CORTEX; RATS; RATS, INBRED STRAINS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0031942214     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(199803)33:3<281::AID-JMS631>3.0.CO;2-W     Document Type: Article

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