Antiepileptic drug withdrawal - A good idea?

Pharmacotherapy

Volumn 18, Issue 2 I, 1998, Pages 235-241

  Buna, Donna K ^a  

^a KELOWNA GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT;

ATAXIA; ELECTROENCEPHALOGRAM; EPILEPSY; HUMAN; MENTAL DEFICIENCY; NYSTAGMUS; PROGNOSIS; RELAPSE; REVIEW; SOMNOLENCE; WITHDRAWAL SYNDROME;

ANTICONVULSANTS; CLINICAL TRIALS; EPILEPSY; HUMANS; RECURRENCE; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0031941723     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (26)

1. Chadwick D, Reynolds, EH. When do epileptic patients need treatment? Starting and stopping medication. Br Med J 1985;290:1885-8.
2. Shinnar S, Berg AT. Withdrawal of antiepileptic drugs. Curr Opin Neurol 1995;8:103-6.
3. Overweg J. Withdrawal of antiepileptic drugs (AEDs) in seizure-free patients, risk factors for relapse with special attention for the EEG. Seizure 1995;4:19-36.
4. Chadwick D, Taylor J, Johnson T. Outcomes after seizure recurrence in people with well-controlled epilepsy and the factors that influence it. Epilepsia 1996;37:1043-50.
5. Jacoby A, Johnson A, Chadwick D, et al. Psychosocial outcomes of antiepileptic drug discontinuation. Epilepsia 1992;33:1123-31.
6. Medical Research Council Antiepileptic Drug Withdrawal Study Group. Randomized study of antiepileptic drug withdrawal in patients in remission. Lancet 1991;337:1175-80.
7. Begley CE, Annegers JF, Lairson DR, Reynolds TF, Hauser WA. Cost of epilepsy in the United States: a model based on incidence and prognosis. Epilepsia 1994;35:1230-43.
8. Emerson R, D'Souza BJ, Vining EP, Holden KR, Mellits ED, Freeman JM. Stopping medication in children with epilepsy. N Engl J Med 1981;304:1125-9.
9. Mastropaolo C, Tondi M, Carboni F, Manca S, Zoroddu F. Prognosis after therapy discontinuation in children with epilepsy. Eur Neurol 1992;32:141-5.
10. Collaborative Group for Epidemiology of Epilepsy. Adverse reactions to antiepileptic drugs: A multicenter survey of clinical practice. Epilepsia 1986;27:323-30.
11. Shinnar S, Vining EPG, Mellits ED, et al. Discontinuing antiepileptic medication in children with epilepsy after two years without seizures. A prospective study. N Engl J Med 1985;313:976-80.
12. American Academy of Pediatrics Committee on Drugs. Behavioral and cognitive effects of anticonvulsant therapy. Pediatrics 1985;76:644-7.
13. Arts WFM, Visser LH, Loonen MCB, et al. Follow-up of 146 children with epilepsy after withdrawal of antiepileptic therapy. Epilepsia 1988;20:244-50.
14. Matricardi M, Brinciotti M, Benedetti P. Outcome after discontinuation of antiepileptic therapy in children with epilepsy. Epilepsia 1989;30:582-9.
15. Tennison M, Greenwood R, Lewis D, Thorn M. Discontinuing antiepileptic drugs in children with epilepsy. A comparison of six week and nine month taper period. N Engl J Med 1994;330:1407-10.
16. Shinnar S, Berg AT, Moshe SL, et al. Discontinuing antiepileptic drugs in children with epilepsy: a prospective study. Ann Neurol 1994;35:534-45.
17. Donati R, Hassink RI, Jung H, Vassella F. Factors predicting the risk of relapse after antiepileptic drug discontinuation in children with partial seizures. Eur J Pediatr 1995;154(suppl 3):S44-7.
18. Murakami M, Konishi T, Naganuma Y, Hongou K, Yamatani M. Withdrawal of antiepileptic drug treatment in childhood epilepsy: factors related to age. J Neurol Neurosurg Psychiatry 1995;59:477-81.
19. Callaghan N, Garrett A, Goggin T. Withdrawal of anticonvulsant drugs in patients free of seizures for two years. N Engl J Med 1988;318:942-6.
20. Berg A, Shinnar S. A meta-analysis of anticonvulsant withdrawal trials. Neurology 1994;44:601-9.
21. Ketter TA, Malow BA, Flamini R, White SR, Post RM, Theodore WH. Anticonvulsant withdrawal-emergent psychopathology. Neurology 1994;44:55-61.
22. Hauser WA, Kurland LT. The epidemiology of epilepsy in Rochester, Minnesota. Epilepsia 1975;16:1-66.
23. Tinuper P, Avoni P, Riva R, Provini F, Lugaresi E, Baruzzi A. The prognostic value of the electroencephalogram in antiepileptic drug withdrawal in partial epilepsies. Neurology 1996; 47:76-8.
24. Mattson RH, Cramer JA, Collins JF. Prognosis for total control of complex partial and secondarily generalized tonic clonic seizures. Neurology 1996;47:68-76.
25. Chadwick D. Prognostic index for recurrence of seizures after remission of epilepsy. BMJ 1993;306:1374-8.
26. American Academy of Neurology. Practice parameter: a guideline for discontinuing antiepileptic drugs in seizure-free patients - summary statement. Neurology 1996;47:600-2.