Platelet activation supports the development of venous thrombosis in hyperlipidemic rats

Blood Coagulation and Fibrinolysis

Volumn 9, Issue 1, 1998, Pages 47-53

  Cignarella, A ^a   Mussoni, L ^a   Mannucci, L ^a   Ferioli, E ^a   Puglisi, L ^a   Tremoli, E ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Diabetes; Hyperlipidemia; Streptozotocin; Thromboxane; Venous thrombosis; Yoshida rats

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; FIBRINOLYSIS; HYPERLIPIDEMIA; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; THROMBOCYTE ACTIVATION; VEIN THROMBOSIS;

EID: 0031941225     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-199801000-00006     Document Type: Article

References (33)

1. Smith EB, Ashall C. Fibrinolysis and plasminogen concentration in aortic intima in relation to death following myocardial infarction. Atherosclerosis 1985; 55: 171-186.
2. Hamsten A, Wiman B, De Faire U, Blomback M. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med 1985; 313: 1557-1563.
3. Marckmann P, Sandstroøm B, Jespersen J. The variability of and associations between measeures of blood coagulation, fibrinolysis and blood lipids. Atherosclerosis 1992; 96: 235-244.
4. Jarrett RJ. Cardiovascular disease and hypertension in diabetes mellitus. Diabetes Metab Rev 1989; 5: 547-558.
5. Sobel BE, Hirsh J. Principles and practice of coronary thrombolysis and conjunctive treatment. Am J Cardiol 1991; 68: 382-388.
6. Eisenberg PR, Miletich JP, Sobel BE. Factors responsible for differential procoagulant effects of diverse plasminogen activators in plasma. Fibrinolysis 1991; 5: 217-224.
7. Assmann G, Brewer HB. Genetic (primary) forms of hypertrygliceridemia. Am J Cardiol 1991; 68: 13A-16A.
8. Mussoni L, Mannucci L, Sirtori M, Camera M, Maderna P, Sironi L, et al. Hypertriglyceridcmia and regulation of fibrinolytic activity. Arterioscler Thromb 1992; 12: 19-27.
9. Tremoli E, Camera M, Maderna P, Sironi L, Prati L, Colli S, et al. Increased synthesis of plasminogen activator inhibitor-1 by cultured human endothelial cells exposed to native and modified LDLs: an LDL receptor-independent phenomenon. Arterioscler Thromb 1993; 13: 338-346.
10. Etingin OR, Hajjar DP, Hajjar KA, Harpel PC, Nachman RL. Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells: a potential mechanism in thrombogenesis. J Biol Chem 1991; 266: 2459-2465.
11. Eynard AR, Tremoli E, Caruso D, Magni F, Sirtori CR, Galli G. Platelet formation of 12-hydroxyeicosatetraenoic acid and thromboxane B2 is increased in type IIA hypercholesterolemic subjects. Atherosclerosis 1986; 60: 61-66.
12. Katayama S, Inaba M, Maruno Y, Omoto A, Kawazu S, Ishii J. Increased thromboxane B2 excretion in diabetes mellitus. J Lab Clin Med 1987; 109: 711-717.
13. Puglisi L, Caruso P, Pinna C, Caratozzolo O. Alteration of lipid metabolism potentiates experimentally-induced venous thrombosis in the rat. Thromb Haemorrh Disorders 1992; 5: 51-54.
14. Naimi S, Goldstein R, Nothman MM, Wilgram GF, Proger S. Cardiovascular lesions and changes in blood coagulation and fibrinolysis associated with diet-induced lipemia in the rat. J Clin Invest 1982; 41: 1708-1719.
15. McIntosh GH, McLennan PL, Lawson CA, Bolman FH, Charnock JS. The influence of dietary fats on plasma lipids, blood pressure and coagulation indices in the rat. Atherosclerosis 1985; 55: 125-134.
16. Padrò T, Villaverde CA, Canovas M. Hyperlipemia, fibrinolysis and atherosclerosis. Thromb Res 1988; 49: 519-530.
17. Fantappiè S, Catapano AL, Cancellieri L, Fasoli E, De Fabiani E, Bertolini M, et al. Plasma lipoproteins and cholesterol metabolism in Yoshida rats: an animal model of spontaneous hyperlipidemia. Life Sci 1992; 50: 1913-1924.
18. Junod A, Lambert AE, Orci L, Pictet R, Gonet AE, Renold AE. Studies of the diabetogenic action of streptozotocin. Proc Soc Exp Biol Med 1967; 126: 201-205.
19. Patrono C, Ciabattoni G, Pinca E, Pugliese E, Castrucci G, De Salvo A, et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. Thromb Res 1980; 17: 317-327.
20. David JL, Legrand Y, Caen J. Essai d'induction d'une thrombose experimentale chez le lapin au moyen d'un collagen purifie. C R Soc Biol 1968; 162: 1763-1766.
21. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
22. Verheijen JH, Mullaart E, Chang GTC, Kluft C, Wijngaards G. A simple sensitive assay for extrinsic (tissue-type) plasminogen activator applicable to measurements in plasma. Thromb Haemost 1982; 48: 266-269.
23. Verheijen JH, Chang GTC, Kluft C. Evidence for the occurrence of a fast-acting inhibitor for tissue-type plasminogen activator in human plasma. Thromb Haemost 1984; 51: 392-395.
24. Smokovitis A, Auerswald W, Müller K, Clopath P, Binder BR. The effect of alloxan-induced diabetes on tissue plasminogen activator activity and plasmin inhibition in the rat. Thromb Res 1981; 23: 421-424.
25. Fumagalli G, Angelaccio E, Lombardo N, Clementi F. Morphometric and ultrastructural study of experimental venous thrombosis: effects of defibrotide, an antithrombotic agent. Haemostasis 1987; 17: 361-370.
26. 2 receptor antagonist sodium 4-[[1-[[[(4-chlorophenyl)sulfonyl]amino]methyl]cyclopentyl] methyl]benzeneacetate. Arzneimittelforschung 1994; 44: 1203-1207.
27. Schumacher WA, Heran CL, Steinbacher TE, Youssef S, Ogletree ML. Superior activity of a thromboxane receptor antagonist as compared with aspirin in rat models of arterial and venous thrombosis. J Cardiovasc Pharmacol 1993; 22: 526-533.
28. Herbert JM, Bernat A, Maffrand JP. Importance of platelets in experimental venous thrombosis in the rat. Blood 1992; 80: 2281-2286.
29. Morishita K, Wada M, Kumada T, Tanaka T, Tomikawa M, Iwamoto M. Effect of ticlopidine and other antithrombotics on the venous thrombosis induced by endothelial damage of jugular vein in the rat. Thromb Res 1991; 63: 373-384.
30. Padrò T, Emeis JJ. Effect of different dietary induced hyperlipaemias on rat plasma fibrinolytic components. Fibrinolysis 1990; 4: 161-167.
31. Gryglewsky RJ, Moncada S. Polyunsaturated fatty acids and thrombosis. Eur J Clin Invest 1979; 9: 1-2.
32. Nordoøy A. Dietary fatty acids and thrombosis. Atherosclerosis 1988; 70: 192-203.
33. Reaven GM, Chen Y-DI. Role of insulin in regulation of lipoprotein metabolism in diabetes. Diabetes Metab Rev 1988; 4: 639-652.