Airway hypersecretion and mucociliary dysfunction in asthma

Folia Pharmacologica Japonica

Volumn 111, Issue 4, 1998, Pages 257-263

  Tamaoki, Jun ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Airway epithelium, leukotriene; Airway hypersecretion; Ion transport; Mucociliary transport

Indexed keywords

HISTAMINE; HISTAMINE H2 RECEPTOR ANTAGONIST; LEUKOTRIENE; MUCIN; OVALBUMIN;

AIRFLOW; ASTHMA; BRONCHOSPASM; CHLORIDE TRANSPORT; CILIATED EPITHELIUM; GOBLET CELL; HUMAN; MUCOCILIARY TRANSPORT; MUCUS SECRETION; NONHUMAN; RESPIRATORY EPITHELIUM; REVIEW; WATER TRANSPORT;

EID: 0031941085     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.111.257     Document Type: Review

References (26)

1. Bateman JRM, Pavia D, Sheahan NF, Agnew JE and Clarke SW: Impaired tracheobronchial clearance in patients with mild stable asthma. Thorax 38, 463-467 (1983)
2. Messina MS, O'Riordan TG and Smaldone GC: Changes in mucociliary clearance during acute exacerbations of asthma. Am Rev Respir Dis 143, 993-997 (1991)
3. Wanner A, Salath M and O'Riordan TG: Mucociliary clearance in the airways. Am J Respir Grit Care Med 154, 1868-1902 (1996)
4. Annesi I and Kauffmann F: Is respiratory mucus secretion really an innocent disorder? Am Rev Respir Dis 134, 688-693 (1986)
5. Kaliner M, Marom Z, Patow C and Shelhamer J: Human respiratory mucus. J Allergy Clin Immunol 73, 318-323 (1984)
6. Shimura S, Andoh Y, Haraguchi M and Shirato K: Continuity of airway goblet cells and intraluminal mucus in the airways of patients with bronchial asthma. Eur Respir J 9, 1395-1401 (1996)
7. Aikawa T, Shimura S, Sasaki H, Ebina M and Takishima T: Marked goblet cell hyperplasia with mucus accumulation in the airways who died of severe acute asthma attack. Chest 101, 916-921 (1992)
8. Welsh MJ: Electrolyte transport by airway epithelia. Physiol Rev 67, 1143-1184 (1987)
9. Shimura S, Sasaki T, Sasaki H and Takishima T: Chemical properties of bronchorrhea sputum in bronchial asthma. Chest 94, 1211-1215 (1988)
10. Tokuyama K, Kuo HP, Rohde JAL, Barnes PJ and Rogers DF: Neural control of goblet cell secretion in guinea pig airways. Am J Physiol 259, L108-L115 (1990)
11. Tamaoki J, Chiyotani A, Tagaya E, Takemura H and Konno K: Cholinergic control of rabbit tracheal transepithelial potential difference in vivo. Eur Respir J 9, 1632-1636 (1996)
12. Nadel JA: Neural control of airway submucosal gland secretion. Eur J Respir Dis 64, Suppl 128, 322-326 (1983)
13. Tamaoki J, Chiyotani A, Tagaya E, Sakai N and Konno K: Effect of long-term oxitropium bromide on airway secretion in chronic bronchitis and diffuse panbronchiolitis. Thorax 49, 545-548 (1994)
14. Kuo H-P, Rohde JAL, Tokuyama K, Barnes PJ and Rogers DF: Capsaicin and sensory neuropeptide stimulation of goblet cell secretion in guinea-pig trachea. J Physiol 431, 629-641 (1990)
15. Tamaoki J, Ueki IF, Widdicombe JH and Nadel JA: Stimulation of Cl secretion by neurokinin A and neurokinin B in canine tracheal epithelium. Am Rev Respir Dis 137, 899-902 (1988)
16. Shelhamer JH, Marom Z and Kaliner M: Immunologic and neuropharmacologic stimulation of mucous glycoprotein release from human airways in vitro. J Clin Invest 66, 1400-1408 (1980)
17. 2 receptor-mediated airway goblet cell secretion and its modulation by histamine-degrading enzymes. J Allergy Clin Immunol 99, 233-238 (1997)
18. Marin MG, Davis B and Nadel JA: Effect of histamine on electrical and ion transport properties of tracheal epithelium. J Appl Physiol 42, 735-738 (1977)
19. Marin MG: Pharmacology of airway secretion. Pharmacol Rev 38, 273-289 (1986)
20. Tamaoki J, Sakai N, Isono K, Kanemura T and Takizawa T: Effects of platelet-activating factor on bioelectric properties of cultured tracheal and bronchial epithelia. J Allergy Clin Immunol 87, 1042-1049 (1991)
21. Tamaoki J, Kanemura T, Kobayashi K, Sakai N and Takizawa T: Endothelin stimulates ciliary beat frequency and Cl secretion in canine cultured tracheal epithelium. Am J Respir Cell Mol Biol 4, 426-431 (1991)
22. Mezey RJ, Cohn MA, Fernadez RJ, Januszkiewicz AJ and Wanner A: Mucociliary transport in allergic patients with antigen-induced bronchospasm. Am Rev Respir Dis 118, 677-684 (1978)
23. Ahmed T, Greenblatt DW, Birch S, Marchette B and Wanner A: Abnormal mucociliary transport in patients with antigen-induced bronchospasm: role of SRS-A. Am Rev Respir Dis 124, 110-114 (1981)
24. Joki S, Saano V, Koskela T, Toskala E, Bray MA and Nuutinen J: Effect of leukotriene D4 on ciliary activity in human, guinea-pig and rat respiratory mucosa. Pulm Pharmacol 9, 231-238 (1996)
25. Tamaoki J, Kondo M and Takizawa T: Adenosine- mediated cyclic AMP-dependent inhibition of ciliary activity in rabbit tracheal epithelium. Am Rev Respir Dis 139, 441-445 (1989)
26. Wanner A: Effects of methylxanthines on airway mucociliary function. Am J Med 79, Suppl 6A, 16- 21 (1985)