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Volumn 28, Issue 1, 1998, Pages 121-134

The immune response to Leishmania: Mechanisms of parasite control and evasion

Author keywords

Evasion mechanisms; Glycoinositolphospholipids; Interleukin 12; Leishmania; Lipophosphoglycan; Macrophages; Nitric oxide synthase; Persistence of parasites; T helper lymphocytes (Th1, Th2); Transforming growth factor

Indexed keywords

GLYCOPHOSPHOLIPID; INTERLEUKIN 12; LIPOPHOSPHOGLYCAN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031940263     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(97)00169-0     Document Type: Conference Paper
Times cited : (223)

References (117)
  • 2
    • 0028963375 scopus 로고
    • Stage-specific binding of Leishmania donovani to the sand fly vector midgut is regulated by conformational changes in the abundant surface lipophosphoglycan
    • [2] Sacks DL, Pimenta PFP, McConville MJ, Schneider P, Turco SJ. Stage-specific binding of Leishmania donovani to the sand fly vector midgut is regulated by conformational changes in the abundant surface lipophosphoglycan. J Exp Med 1995; 181: 685-697.
    • (1995) J Exp Med , vol.181 , pp. 685-697
    • Sacks, D.L.1    Pimenta, P.F.P.2    McConville, M.J.3    Schneider, P.4    Turco, S.J.5
  • 3
    • 0027672713 scopus 로고
    • Leishmania-macrophage interactions: Multiple receptors, multiple ligands, and diverse cellular responses
    • [3] Mosser DM, Rosenthal LA. Leishmania-macrophage interactions: multiple receptors, multiple ligands, and diverse cellular responses. Semin Cell Biol 1993; 4: 315-325.
    • (1993) Semin Cell Biol , vol.4 , pp. 315-325
    • Mosser, D.M.1    Rosenthal, L.A.2
  • 4
    • 0025274399 scopus 로고
    • Isolation of genes showing increased or unique expression in the infective promastigotes of Leishmania major
    • [4] Coulson RMR, Smith DF. Isolation of genes showing increased or unique expression in the infective promastigotes of Leishmania major. Mol Biochem Parasitol 1990; 40: 63-76.
    • (1990) Mol Biochem Parasitol , vol.40 , pp. 63-76
    • Coulson, R.M.R.1    Smith, D.F.2
  • 5
    • 0028970043 scopus 로고
    • Identification of intra- and interspecific Leishmania genetic polymorphisms by arbitrary primed polymerase chain reactions and use of polymorphic DNA to identify differentially regulated genes
    • [5] Pogue GP, Koul S, Lee NS, Dwyer DM, Nakhasi HL. Identification of intra- and interspecific Leishmania genetic polymorphisms by arbitrary primed polymerase chain reactions and use of polymorphic DNA to identify differentially regulated genes. Parasitol Res 1995; 81: 282-290.
    • (1995) Parasitol Res , vol.81 , pp. 282-290
    • Pogue, G.P.1    Koul, S.2    Lee, N.S.3    Dwyer, D.M.4    Nakhasi, H.L.5
  • 6
    • 0028967857 scopus 로고
    • Cell surface components of Leishmania: Identification of a novel parasite lectin
    • [6] Smith DF, Rangarajan D. Cell surface components of Leishmania: identification of a novel parasite lectin. Glycobiology 1995; 5: 161-166.
    • (1995) Glycobiology , vol.5 , pp. 161-166
    • Smith, D.F.1    Rangarajan, D.2
  • 7
    • 0030014943 scopus 로고    scopus 로고
    • Identification and overexpression of the A2 amastigote-specific protein in Leishmania donovani
    • [7] Zhang WW, Charest H, Ghedin E, Matlashewski G. Identification and overexpression of the A2 amastigote-specific protein in Leishmania donovani. Mol Biochem Parasitol 1996; 78: 79-90.
    • (1996) Mol Biochem Parasitol , vol.78 , pp. 79-90
    • Zhang, W.W.1    Charest, H.2    Ghedin, E.3    Matlashewski, G.4
  • 8
    • 0023026854 scopus 로고
    • Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages
    • [8] Handman E, Schnur LF, Spithill TW, Mitchell GF. Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages. J Immunol 1986; 137: 3608-3613.
    • (1986) J Immunol , vol.137 , pp. 3608-3613
    • Handman, E.1    Schnur, L.F.2    Spithill, T.W.3    Mitchell, G.F.4
  • 9
    • 0025356813 scopus 로고
    • Lipophosphoglycan expression and virulence in ricin-resistant variants of Leishmania major
    • [9] Elhay M, Kelleher M, Bacic A, et al. Lipophosphoglycan expression and virulence in ricin-resistant variants of Leishmania major. Mol Biochem Parasitol 1990; 40: 255-268.
    • (1990) Mol Biochem Parasitol , vol.40 , pp. 255-268
    • Elhay, M.1    Kelleher, M.2    Bacic, A.3
  • 10
    • 0025670262 scopus 로고
    • Characterization of Leishmania donovani variant clones using anti-lipophosphoglycan monoclonal antibodies
    • [10] McNeely TB, Tolson DL, Pearson TW, Turco SJ. Characterization of Leishmania donovani variant clones using anti-lipophosphoglycan monoclonal antibodies. Glycobiology 1990; 1: 63-69.
    • (1990) Glycobiology , vol.1 , pp. 63-69
    • McNeely, T.B.1    Tolson, D.L.2    Pearson, T.W.3    Turco, S.J.4
  • 11
    • 0026777333 scopus 로고
    • Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages
    • [11] Liu X, Chang K-P. Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages. Proc Natl Acad Sci USA 1992; 89: 4991-4995.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4991-4995
    • Liu, X.1    Chang, K.-P.2
  • 12
    • 0028142227 scopus 로고
    • Genetic rescue or surface metalloproteinase (gp63) deficiency in Leishmania amazonensis variants increases their infection of macrophages at the early phase
    • [12] McGwire B, Chang KP. Genetic rescue or surface metalloproteinase (gp63) deficiency in Leishmania amazonensis variants increases their infection of macrophages at the early phase. Mol Biochem Parasitol 1994; 66: 345-353.
    • (1994) Mol Biochem Parasitol , vol.66 , pp. 345-353
    • McGwire, B.1    Chang, K.P.2
  • 13
    • 0028859537 scopus 로고
    • Aspecialized pathway affecting virulence glycoconjugates of Leishmania
    • [13] Descoteaux A, Luo Y, Turco SJ, Beverly SM. Aspecialized pathway affecting virulence glycoconjugates of Leishmania. Science 1995; 269: 1869-1872.
    • (1995) Science , vol.269 , pp. 1869-1872
    • Descoteaux, A.1    Luo, Y.2    Turco, S.J.3    Beverly, S.M.4
  • 15
    • 0010621394 scopus 로고    scopus 로고
    • Leishmania cysteine proteinases: Structure, functions and possibilities for exploitation
    • [15] Coombs G. Leishmania cysteine proteinases: structure, functions and possibilities for exploitation. Abstr 3. Acta Parasitol Turc 1997; 21(Suppl): 5.
    • (1997) Acta Parasitol Turc , vol.21 , Issue.SUPPL. , pp. 5
    • Coombs, G.1
  • 16
    • 0031005660 scopus 로고    scopus 로고
    • Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan
    • [16] Desjardins M, Descoteaux A. Inhibition of phagolysosomal biogenesis by the Leishmania lipophosphoglycan. J Exp Med 1997; 185: 2061-2068.
    • (1997) J Exp Med , vol.185 , pp. 2061-2068
    • Desjardins, M.1    Descoteaux, A.2
  • 17
    • 0010551773 scopus 로고    scopus 로고
    • Targeted deletion of gp63 metalloproteinase genes in L. Major
    • [17] McMaster R, Joshi P, Kelly B. Targeted deletion of gp63 metalloproteinase genes in L. major. Abstr 102. Acta Parasitol Turc 1997; 21(Suppl): 55.
    • (1997) Acta Parasitol Turc , vol.21 , Issue.SUPPL. , pp. 55
    • McMaster, R.1    Joshi, P.2    Kelly, B.3
  • 18
    • 0030841734 scopus 로고    scopus 로고
    • Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2
    • [18] Zhang W., Matlashewski G. Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2. Proc Natl Acad Sci USA 1997; 94: 8807-8811.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8807-8811
    • Zhang, W.1    Matlashewski, G.2
  • 19
    • 0024812189 scopus 로고
    • Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major
    • [19] Müller I, Garcia-Sanz JA, Titus R, Behin R, Louis J. Analysis of the cellular parameters of the immune responses contributing to resistance and susceptibility of mice to infection with the intracellular parasite, Leishmania major. Immunol Rev 1989; 112: 95-113.
    • (1989) Immunol Rev , vol.112 , pp. 95-113
    • Müller, I.1    Garcia-Sanz, J.A.2    Titus, R.3    Behin, R.4    Louis, J.5
  • 20
    • 0024805717 scopus 로고
    • Experimental visceral leishmaniasis: Role of endogenous IFN-γ in host defense and tissue granulomatous response
    • [20] Squires KE, Schreiber RD, McElrath MJ, Rubin BY, Anderson SL, Murray HW. Experimental visceral leishmaniasis: role of endogenous IFN-γ in host defense and tissue granulomatous response. J Immunol 1989; 143: 4244-4249.
    • (1989) J Immunol , vol.143 , pp. 4244-4249
    • Squires, K.E.1    Schreiber, R.D.2    McElrath, M.J.3    Rubin, B.Y.4    Anderson, S.L.5    Murray, H.W.6
  • 21
    • 0027304337 scopus 로고
    • Immunology of leishmaniasis
    • [21] Liew FY, O'Donnell CA. Immunology of leishmaniasis. Adv Parasitol 1993; 32: 161-259.
    • (1993) Adv Parasitol , vol.32 , pp. 161-259
    • Liew, F.Y.1    O'Donnell, C.A.2
  • 22
    • 0028204812 scopus 로고
    • Dichotomy in the human CD4+ T-cell response to Leishmania parasites
    • [22] Kemp M, Kurtzhals JAL, Kharazmi A, Theander TG. Dichotomy in the human CD4+ T-cell response to Leishmania parasites. APMIS 1994; 102: 81-88.
    • (1994) APMIS , vol.102 , pp. 81-88
    • Kemp, M.1    Kurtzhals, J.A.L.2    Kharazmi, A.3    Theander, T.G.4
  • 23
    • 0029061666 scopus 로고
    • IL-12 enhances Th1-type responses in human Leishmania donovani infections
    • [23] Ghalib HW, Whittle JA, Kubin M, et al. IL-12 enhances Th1-type responses in human Leishmania donovani infections. J Immunol 1995; 154: 4623-4629.
    • (1995) J Immunol , vol.154 , pp. 4623-4629
    • Ghalib, H.W.1    Whittle, J.A.2    Kubin, M.3
  • 24
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • [24] Reiner SL, Locksley RM. The regulation of immunity to Leishmania major. Ann Rev Immunol 1995; 13: 151-177.
    • (1995) Ann Rev Immunol , vol.13 , pp. 151-177
    • Reiner, S.L.1    Locksley, R.M.2
  • 25
    • 0029840157 scopus 로고    scopus 로고
    • Interleukin-12 restores interferon-γ production and cytotoxic responses in visceral leishmaniasis
    • [25] Bacellar O, Brodskyn C, Guerreiro J, et al. Interleukin-12 restores interferon-γ production and cytotoxic responses in visceral leishmaniasis. J Infect Dis 1996; 173: 1515-1518.
    • (1996) J Infect Dis , vol.173 , pp. 1515-1518
    • Bacellar, O.1    Brodskyn, C.2    Guerreiro, J.3
  • 27
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • [27] Mattner F, Magram J, Ferrante J, et al. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur J Immunol 1996; 26: 1553-1559.
    • (1996) Eur J Immunol , vol.26 , pp. 1553-1559
    • Mattner, F.1    Magram, J.2    Ferrante, J.3
  • 28
    • 0029982872 scopus 로고    scopus 로고
    • Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication
    • [28] Vieira LQ, Goldschmidt M, Nashleanas M, Pfeffer K, Mak T, Scott P. Mice lacking the TNF receptor p55 fail to resolve lesions caused by infection with Leishmania major, but control parasite replication. J Immunol 1996; 157: 827-835.
    • (1996) J Immunol , vol.157 , pp. 827-835
    • Vieira, L.Q.1    Goldschmidt, M.2    Nashleanas, M.3    Pfeffer, K.4    Mak, T.5    Scott, P.6
  • 29
    • 0030747793 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo
    • [29] Lohoff M, Ferrick D, Mittrücker H-W, et al. Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo. Immunity 1997; 6: 681-689.
    • (1997) Immunity , vol.6 , pp. 681-689
    • Lohoff, M.1    Ferrick, D.2    Mittrücker, H.-W.3
  • 30
    • 0030911399 scopus 로고    scopus 로고
    • Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis
    • [30] Murray HW. Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis. J Infect Dis 1997; 175: 1477-1479.
    • (1997) J Infect Dis , vol.175 , pp. 1477-1479
    • Murray, H.W.1
  • 31
    • 0019471126 scopus 로고
    • Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages
    • [31] Murray HW. Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages. J Exp Med 1981; 153: 1302-1315.
    • (1981) J Exp Med , vol.153 , pp. 1302-1315
    • Murray, H.W.1
  • 32
    • 0027175624 scopus 로고
    • Antimicrobial and immunopathologic effects of cytokine-induced nitric oxide synthesis
    • [32] Green SJ, Nacy CA. Antimicrobial and immunopathologic effects of cytokine-induced nitric oxide synthesis. Curr Opin Infect Dis 1993; 6: 384-396.
    • (1993) Curr Opin Infect Dis , vol.6 , pp. 384-396
    • Green, S.J.1    Nacy, C.A.2
  • 33
    • 0028129526 scopus 로고
    • Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major
    • [33] Stenger S, Thüring H, Röllinghoff M, Bogdan C. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J Exp Med 1994; 180: 783-793.
    • (1994) J Exp Med , vol.180 , pp. 783-793
    • Stenger, S.1    Thüring, H.2    Röllinghoff, M.3    Bogdan, C.4
  • 34
    • 0029035476 scopus 로고
    • Altered immune responses in mice lacking inducible nitric oxide synthase
    • [34] Wei X-q, Charles IG, Smith A, et al. Altered immune responses in mice lacking inducible nitric oxide synthase. Nature 1995; 375: 408-411.
    • (1995) Nature , vol.375 , pp. 408-411
    • Wei, X.-Q.1    Charles, I.G.2    Smith, A.3
  • 35
    • 0031085771 scopus 로고    scopus 로고
    • Of microbes, macrophages and NO
    • [35] Bogdan C. Of microbes, macrophages and NO. Behring Inst Res Commun 1997; 99: 58-72.
    • (1997) Behring Inst Res Commun , vol.99 , pp. 58-72
    • Bogdan, C.1
  • 36
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon-γ-independent mechanism
    • [36] Sadick MD, Heinzel FP, Holaday BJ, Pu RT, Dawkins RS, Locksley RM. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon-γ-independent mechanism. J Exp Med 1990; 171: 115-127.
    • (1990) J Exp Med , vol.171 , pp. 115-127
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 38
    • 0028970948 scopus 로고
    • Transforming growth factor-β in human cutaneous leishmaniasis
    • [38] Barral A, Teixeira M, Reis P, et al. Transforming growth factor-β in human cutaneous leishmaniasis. Am J Pathol 1995; 147: 947-954.
    • (1995) Am J Pathol , vol.147 , pp. 947-954
    • Barral, A.1    Teixeira, M.2    Reis, P.3
  • 39
    • 0030967584 scopus 로고    scopus 로고
    • An in vitro model for infection with Leishmania major that mimics the immune response in mice
    • [39] Soares MBP, David JR, Titus RG. An in vitro model for infection with Leishmania major that mimics the immune response in mice. Infect Immun 1997; 65: 2837-2845.
    • (1997) Infect Immun , vol.65 , pp. 2837-2845
    • Soares, M.B.P.1    David, J.R.2    Titus, R.G.3
  • 40
    • 0025649097 scopus 로고
    • Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9
    • [40] Puentes SM, da Silva RP, Sacks DL, Hammer CH, Joiner KA. Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9. J Immunol 1990; 145: 4311-4316.
    • (1990) J Immunol , vol.145 , pp. 4311-4316
    • Puentes, S.M.1    Da Silva, R.P.2    Sacks, D.L.3    Hammer, C.H.4    Joiner, K.A.5
  • 41
    • 0025987531 scopus 로고
    • Leishmanial protein kinases phosphorylate components of the complement cascade
    • [41] Hermoso T, Fishelson Z, Becker S, Hirschberg K, Jaffe CL. Leishmanial protein kinases phosphorylate components of the complement cascade. EMBO J 1991; 10: 4061-4067.
    • (1991) EMBO J , vol.10 , pp. 4061-4067
    • Hermoso, T.1    Fishelson, Z.2    Becker, S.3    Hirschberg, K.4    Jaffe, C.L.5
  • 43
    • 0029046678 scopus 로고
    • Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion and resistance to complement-mediated lysis
    • [43] Brittingham A, Morrison CJ, McMaster WR, McGwire BS, Chang K-P, Mosser DM. Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion and resistance to complement-mediated lysis. J Immunol 1995; 155: 3102-3111.
    • (1995) J Immunol , vol.155 , pp. 3102-3111
    • Brittingham, A.1    Morrison, C.J.2    McMaster, W.R.3    McGwire, B.S.4    Chang, K.-P.5    Mosser, D.M.6
  • 44
    • 0029948726 scopus 로고    scopus 로고
    • Leishmania mayor-human macrophage interactions: Cooperation between Mac-1 (CD11b/CD18) and complement receptor type 1 (CD35) in promastigote adhesion
    • [43a] Rosenthal LA, Sutterwala FS, Kehrli ME, Mosser, DM. Leishmania mayor-human macrophage interactions: cooperation between Mac-1 (CD11b/CD18) and complement receptor type 1 (CD35) in promastigote adhesion. Infect Immun 1996; 64: 2206-2215.
    • (1996) Infect Immun , vol.64 , pp. 2206-2215
    • Rosenthal, L.A.1    Sutterwala, F.S.2    Kehrli, M.E.3    Mosser, D.M.4
  • 45
    • 0021080912 scopus 로고
    • Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes
    • [44] Wright SD, Silverstein SC. Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes. J Exp Med 1983; 158: 2016-2023.
    • (1983) J Exp Med , vol.158 , pp. 2016-2023
    • Wright, S.D.1    Silverstein, S.C.2
  • 46
    • 0024340791 scopus 로고
    • CR1, the C3b receptor, mediates binding of infective metacydic promastigotes to human macrophages
    • [44a] da Silva R, Hall BF, Joiner KA, Sacks DL. CR1, the C3b receptor, mediates binding of infective metacydic promastigotes to human macrophages. J Immunol 1989; 143: 617-622.
    • (1989) J Immunol , vol.143 , pp. 617-622
    • Da Silva, R.1    Hall, B.F.2    Joiner, K.A.3    Sacks, D.L.4
  • 47
    • 0023203676 scopus 로고
    • The third component of complement (C3) is responsible for the intracellular survival of Leishmania major
    • [45] Mosser DM, Edelson PJ. The third component of complement (C3) is responsible for the intracellular survival of Leishmania major. Nature 1987; 327: 329-331.
    • (1987) Nature , vol.327 , pp. 329-331
    • Mosser, D.M.1    Edelson, P.J.2
  • 48
    • 0000755032 scopus 로고
    • Interactions between Leishmania major and macrophages
    • Zwilling T, Eisenstein T, editors. New York: Marcel Dekker
    • [46] Titus RG,Theodos CM, Shankar A, Hall LR. Interactions between Leishmania major and macrophages. In: Zwilling T, Eisenstein T, editors. Macrophage-pathogen interactions. New York: Marcel Dekker, 1993;437-459.
    • (1993) Macrophage-pathogen Interactions , pp. 437-459
    • Titus, R.G.1    Theodos, C.M.2    Shankar, A.3    Hall, L.R.4
  • 49
    • 0029551775 scopus 로고    scopus 로고
    • Cutaneous leishmaniasis: A model for analysis of the immunoregulation by accessory cells
    • [47] Moll H., Ritter U, Flohé S, Erb K, Bauer C, Blank C. Cutaneous leishmaniasis: a model for analysis of the immunoregulation by accessory cells. Med Microbiol Immunol 1996; 184: 163-168.
    • (1996) Med Microbiol Immunol , vol.184 , pp. 163-168
    • Moll, H.1    Ritter, U.2    Flohé, S.3    Erb, K.4    Bauer, C.5    Blank, C.6
  • 50
    • 0028294578 scopus 로고
    • Intracellular infection by Leishmania donovani inhibits macrophage apoptosis
    • [48] Moore KJ, Matlashewski G. Intracellular infection by Leishmania donovani inhibits macrophage apoptosis. J Immunol 1994; 152: 2930-2937.
    • (1994) J Immunol , vol.152 , pp. 2930-2937
    • Moore, K.J.1    Matlashewski, G.2
  • 51
    • 0026533657 scopus 로고
    • The interaction of Leishmania species with macrophages
    • [49] Alexander J, Russel DG. The interaction of Leishmania species with macrophages. Adv Parasitol 1992; 31: 175-253.
    • (1992) Adv Parasitol , vol.31 , pp. 175-253
    • Alexander, J.1    Russel, D.G.2
  • 52
    • 0027483033 scopus 로고
    • Comparison of receptors required for entry of Leishmania major amastigotes into macrophages
    • [50] Guy RA, Melosevic M. Comparison of receptors required for entry of Leishmania major amastigotes into macrophages. Infect Immun 1993; 61: 1553-1558.
    • (1993) Infect Immun , vol.61 , pp. 1553-1558
    • Guy, R.A.1    Melosevic, M.2
  • 53
    • 0029931163 scopus 로고    scopus 로고
    • C-reactive protein binds to a novel ligand on Leishmania donovani and increases uptake into human macrophages
    • [51] Culley FJ, Harris RA, Kaye PM, McAdam KPWJ, Raynes JG. C-Reactive protein binds to a novel ligand on Leishmania donovani and increases uptake into human macrophages. J Immunol 1996; 156: 4691-4696.
    • (1996) J Immunol , vol.156 , pp. 4691-4696
    • Culley, F.J.1    Harris, R.A.2    Kaye, P.M.3    Kpwj, M.4    Raynes, J.G.5
  • 54
    • 0029993771 scopus 로고    scopus 로고
    • Murine epidermal Langerhans cells do not express inducible nitric oxide synthase
    • [52] Blank C, Bogdan C, Bauer C, Erb K, Moll H. Murine epidermal Langerhans cells do not express inducible nitric oxide synthase. Eur J Immunol 1996; 26: 792-796.
    • (1996) Eur J Immunol , vol.26 , pp. 792-796
    • Blank, C.1    Bogdan, C.2    Bauer, C.3    Erb, K.4    Moll, H.5
  • 55
    • 0022612686 scopus 로고
    • Increased myelopoiesis during Leishmania major infection in mice: Generation of "safe targets", a possible way to evade the effector immune mechanism
    • [53] Mirkovich AM, Galelli A, Allison AC, Modabber FZ. Increased myelopoiesis during Leishmania major infection in mice: generation of "safe targets", a possible way to evade the effector immune mechanism. Clin Exp Immunol 1986; 64: 1-7.
    • (1986) Clin Exp Immunol , vol.64 , pp. 1-7
    • Mirkovich, A.M.1    Galelli, A.2    Allison, A.C.3    Modabber, F.Z.4
  • 56
    • 0027248910 scopus 로고
    • Modulation of macrophage function by transforming growth factor-β, interleukin 4 and interleukin 10
    • [54] Bogdan C, Nathan C. Modulation of macrophage function by transforming growth factor-β, interleukin 4 and interleukin 10. Ann NY Acad Sci 1993; 685: 713-739.
    • (1993) Ann NY Acad Sci , vol.685 , pp. 713-739
    • Bogdan, C.1    Nathan, C.2
  • 57
    • 0021358280 scopus 로고
    • Macrophage activation to kill Leishmania tropica: Defective intracellular killing of amastigotes by macrophages elicited with sterile inflammatory agents
    • [55] Hoover DL, Nacy CA. Macrophage activation to kill Leishmania tropica: defective intracellular killing of amastigotes by macrophages elicited with sterile inflammatory agents. J Immunol 1984; 132: 1487-1493.
    • (1984) J Immunol , vol.132 , pp. 1487-1493
    • Hoover, D.L.1    Nacy, C.A.2
  • 58
    • 0027431908 scopus 로고
    • Resistance of mice to experimental leishmaniasis is associated with more rapid appearance of mature macrophages in vitro and in vivo
    • [56] Sunderkötter C, Kunz M, Steinbrink K, et al. Resistance of mice to experimental leishmaniasis is associated with more rapid appearance of mature macrophages in vitro and in vivo. J Immunol 1993; 151: 4891-4901.
    • (1993) J Immunol , vol.151 , pp. 4891-4901
    • Sunderkötter, C.1    Kunz, M.2    Steinbrink, K.3
  • 59
    • 0028300713 scopus 로고
    • Blood monocytes: Differing effector role in experimental visceral versus cutaneous leishmaniasis
    • [57] Murray HW. Blood monocytes: differing effector role in experimental visceral versus cutaneous leishmaniasis. Parasitol Today 1994; 10: 220-223.
    • (1994) Parasitol Today , vol.10 , pp. 220-223
    • Murray, H.W.1
  • 60
    • 0028366596 scopus 로고
    • Recurrent cutaneous leishmaniasis: A role for persistent parasites
    • [58] Aebischer T. Recurrent cutaneous leishmaniasis: a role for persistent parasites. Parasitol Today 1994; 10: 25-28.
    • (1994) Parasitol Today , vol.10 , pp. 25-28
    • Aebischer, T.1
  • 61
    • 0029976423 scopus 로고    scopus 로고
    • Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase
    • [59] Stenger S, Donhauser N, Thüring H, Röllinghoff M, Bogdan C. Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J Exp Med 1996; 183: 1501-1514.
    • (1996) J Exp Med , vol.183 , pp. 1501-1514
    • Stenger, S.1    Donhauser, N.2    Thüring, H.3    Röllinghoff, M.4    Bogdan, C.5
  • 62
    • 0030588671 scopus 로고    scopus 로고
    • The outcome of the parasitic process initiated by Leishmania infantum in laboratory mice. A tissue-dependent pattern controlled by the Lsh and MHC loci
    • [60] Leclercq V, Lebastard M, Belkaid Y, Louis J, Milon G. The outcome of the parasitic process initiated by Leishmania infantum in laboratory mice. A tissue-dependent pattern controlled by the Lsh and MHC loci. J Immunol 1996; 157: 4537-4545.
    • (1996) J Immunol , vol.157 , pp. 4537-4545
    • Leclercq, V.1    Lebastard, M.2    Belkaid, Y.3    Louis, J.4    Milon, G.5
  • 63
    • 0025215801 scopus 로고
    • Requirement of lipophosphoglycan for intracellular survival of Leishmania donovani within human monocytes
    • [61] McNeely TB, Turco SJ. Requirement of lipophosphoglycan for intracellular survival of Leishmania donovani within human monocytes. J Immunol 1990; 144: 2745-2750.
    • (1990) J Immunol , vol.144 , pp. 2745-2750
    • McNeely, T.B.1    Turco, S.J.2
  • 64
    • 0343775483 scopus 로고
    • Microbial glycolipids: Possible virulence factors that scavenge oxygen radicals
    • [62] Chan J, Fujiwara T, Brennan P, et al. Microbial glycolipids: possible virulence factors that scavenge oxygen radicals. Proc Natl Acad USA 1989; 86: 2453-2457.
    • (1989) Proc Natl Acad USA , vol.86 , pp. 2453-2457
    • Chan, J.1    Fujiwara, T.2    Brennan, P.3
  • 65
    • 0024439986 scopus 로고
    • The promastigote surface protease (gp63) of Leishmania is expressed but differentially processed and localized in the amastigote stage
    • [63] Medina-Acosta E, Karess RE, Schwartz R, Russell DG. The promastigote surface protease (gp63) of Leishmania is expressed but differentially processed and localized in the amastigote stage. Mol Biochem Parasitol 1989; 37: 263-274.
    • (1989) Mol Biochem Parasitol , vol.37 , pp. 263-274
    • Medina-Acosta, E.1    Karess, R.E.2    Schwartz, R.3    Russell, D.G.4
  • 66
    • 0027279941 scopus 로고
    • The lysosomal gp63-related protein in Leishmania mexicana amastigotes is a soluble metalloproteinase with an acidic pH optimum
    • [64] Ilg T, Harbecke D, Overath P. The lysosomal gp63-related protein in Leishmania mexicana amastigotes is a soluble metalloproteinase with an acidic pH optimum. FEBS Lett 1993; 327: 103-107.
    • (1993) FEBS Lett , vol.327 , pp. 103-107
    • Ilg, T.1    Harbecke, D.2    Overath, P.3
  • 67
    • 0029851699 scopus 로고    scopus 로고
    • Surface Zn-proteinase as a molecule for defense of Leishmania mexicana amazonensis promastigotes against cytolysis inside macrophage phagolysosomes
    • [65] Seay MB, Heard PL, Chaudhuri G. Surface Zn-proteinase as a molecule for defense of Leishmania mexicana amazonensis promastigotes against cytolysis inside macrophage phagolysosomes. Infect Immun 1996; 64: 5129-5137.
    • (1996) Infect Immun , vol.64 , pp. 5129-5137
    • Seay, M.B.1    Heard, P.L.2    Chaudhuri, G.3
  • 68
    • 0029797589 scopus 로고    scopus 로고
    • Cytolytic activity in the genus Leishmania: Involvement of a putative pore-forming protein
    • [66] Noronha FSM, Ramalho-Pinto FJ, Horta MF. Cytolytic activity in the genus Leishmania: involvement of a putative pore-forming protein. Infect Immun 1996; 64: 3975-3982.
    • (1996) Infect Immun , vol.64 , pp. 3975-3982
    • Noronha, F.S.M.1    Ramalho-Pinto, F.J.2    Horta, M.F.3
  • 69
    • 0031086474 scopus 로고    scopus 로고
    • Developmentally regulated changes in the cell surface architecture of Leishmania parasites
    • [67] McConville MJ, Ralton JE. Developmentally regulated changes in the cell surface architecture of Leishmania parasites. Behring Inst Res Commun 1997; 99; 34-43.
    • (1997) Behring Inst Res Commun , vol.99 , pp. 34-43
    • McConville, M.J.1    Ralton, J.E.2
  • 70
    • 0028144543 scopus 로고
    • Molecular cloning, characterization, and expression in Escherichia coli of iron superoxide dismutase cDNA from Leishmania donovani chagasi
    • [68] Ismail SO, Skeiky YAW, Bhatia A, Omara-Opyene LA, Gedamu L. Molecular cloning, characterization, and expression in Escherichia coli of iron superoxide dismutase cDNA from Leishmania donovani chagasi. Infect Immun 1994; 62: 657-664.
    • (1994) Infect Immun , vol.62 , pp. 657-664
    • Ismail, S.O.1    Skeiky, Y.A.W.2    Bhatia, A.3    Omara-Opyene, L.A.4    Gedamu, L.5
  • 72
    • 0028861644 scopus 로고
    • Purification, partial characterization and immunolocalization of a proteophosphoglycan secreted by Leishmania mexicana amastigotes
    • [70] Ilg T, Stierhof YD, McConville MJ, Overath P. Purification, partial characterization and immunolocalization of a proteophosphoglycan secreted by Leishmania mexicana amastigotes. Eur J Cell Biol 1995; 66: 205-215.
    • (1995) Eur J Cell Biol , vol.66 , pp. 205-215
    • Ilg, T.1    Stierhof, Y.D.2    McConville, M.J.3    Overath, P.4
  • 73
    • 0029810396 scopus 로고    scopus 로고
    • Purification and structural characterization of a filamentous, mucin-like proteophosphoglycan secreted by Leishmania parasites
    • [71] Ilg T, Stierhof YD, Craik D, Simpson R, Handman E, Bacic A. Purification and structural characterization of a filamentous, mucin-like proteophosphoglycan secreted by Leishmania parasites. J Biol Chem 1996; 271: 21583-21596.
    • (1996) J Biol Chem , vol.271 , pp. 21583-21596
    • Ilg, T.1    Stierhof, Y.D.2    Craik, D.3    Simpson, R.4    Handman, E.5    Bacic, A.6
  • 74
    • 0023116482 scopus 로고
    • Impairment of the oxidative metabolism of mouse peritoneal macrophages by intracellular Leishmania spp
    • [72] Buchmüller-Rouiller Y, Mauèl J. Impairment of the oxidative metabolism of mouse peritoneal macrophages by intracellular Leishmania spp. Infect Immun 1987; 55: 587-593.
    • (1987) Infect Immun , vol.55 , pp. 587-593
    • Buchmüller-Rouiller, Y.1    Mauèl, J.2
  • 75
    • 0026693720 scopus 로고
    • Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C
    • [73] Olivier M, Brownsey RW, Reiner NE. Defective stimulus-response coupling in human monocytes infected with Leishmania donovani is associated with altered activation and translocation of protein kinase C. Proc Natl Acad Sci USA 1992; 89: 7481-7485.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7481-7485
    • Olivier, M.1    Brownsey, R.W.2    Reiner, N.E.3
  • 76
    • 0028021372 scopus 로고
    • Infection of human monocytes by Leishmania results in a defective oxidative burst
    • [74] Passwell JH, Shor R, Smolen J, Jaffe CL. Infection of human monocytes by Leishmania results in a defective oxidative burst. Int J Exp Pathol 1994; 75: 277-284.
    • (1994) Int J Exp Pathol , vol.75 , pp. 277-284
    • Passwell, J.H.1    Shor, R.2    Smolen, J.3    Jaffe, C.L.4
  • 77
    • 0027494552 scopus 로고
    • The lipophosphoglycan of Leishmania and macrophage protein kinase C
    • [75] Descoteaux A, Turco SJ. The lipophosphoglycan of Leishmania and macrophage protein kinase C. Parasitol Today 1993; 9: 468-471.
    • (1993) Parasitol Today , vol.9 , pp. 468-471
    • Descoteaux, A.1    Turco, S.J.2
  • 78
    • 0029966229 scopus 로고    scopus 로고
    • Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani
    • [76] Giorgione JR, Turco SJ, Epand RM. Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani. Proc Natl Acad Sci USA 1996; 93: 11634-11639.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11634-11639
    • Giorgione, J.R.1    Turco, S.J.2    Epand, R.M.3
  • 79
    • 0028200553 scopus 로고
    • Leishmania major surface protease gp63 interferes with the function of human monocytes and neutrophils in vitro
    • [77] Sorensen AL, Hey AS, Kharazmi A. Leishmania major surface protease gp63 interferes with the function of human monocytes and neutrophils in vitro. APMIS 1994; 102: 265-271.
    • (1994) APMIS , vol.102 , pp. 265-271
    • Sorensen, A.L.1    Hey, A.S.2    Kharazmi, A.3
  • 80
    • 0024512492 scopus 로고
    • Inhibitory effects on protein kinase C activity by lipophosphoglycan fragments and glycosylphosphatidyl-inositol antigens of the protozoan parasite Leishmania
    • [78] McNeely TB, Rosen G, Londner MV, Turco SJ. Inhibitory effects on protein kinase C activity by lipophosphoglycan fragments and glycosylphosphatidyl-inositol antigens of the protozoan parasite Leishmania. Biochem J 1989; 259: 601-604.
    • (1989) Biochem J , vol.259 , pp. 601-604
    • McNeely, T.B.1    Rosen, G.2    Londner, M.V.3    Turco, S.J.4
  • 81
    • 0025667811 scopus 로고
    • Effect of glycolipids of Leishmania parasites on human monocyte activity
    • [79] Frankenburg S, Leibovici V, Mansbach N, Turco SJ. Effect of glycolipids of Leishmania parasites on human monocyte activity. J Immunol 1990; 145: 4284-4289.
    • (1990) J Immunol , vol.145 , pp. 4284-4289
    • Frankenburg, S.1    Leibovici, V.2    Mansbach, N.3    Turco, S.J.4
  • 82
    • 0029769511 scopus 로고    scopus 로고
    • Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages
    • [80] Proudfoot L, Nikolaev AV, Feng G-J, et al. Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages. Proc Natl Acad Sci USA 1996; 93: 10984-10989.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10984-10989
    • Proudfoot, L.1    Nikolaev, A.V.2    Feng, G.-J.3
  • 83
    • 0028935560 scopus 로고
    • Glycoinositolphospholipids of Leishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages
    • [81] Proudfoot L, O'Donnell CA, Liew FY. Glycoinositolphospholipids of Leishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages. Eur J Immunol 1995; 25: 745-750.
    • (1995) Eur J Immunol , vol.25 , pp. 745-750
    • Proudfoot, L.1    O'Donnell, C.A.2    Liew, F.Y.3
  • 84
    • 0028854812 scopus 로고
    • Isolation and characterization of the Leishmania donovani kinetoplastid membrane protein-11, a major immunoreactive membrane glycoprotein
    • [82] Jardim A, Funk V, Caprioli RM, Olafson RW. Isolation and characterization of the Leishmania donovani kinetoplastid membrane protein-11, a major immunoreactive membrane glycoprotein. Biochem J 1995; 305: 307-313.
    • (1995) Biochem J , vol.305 , pp. 307-313
    • Jardim, A.1    Funk, V.2    Caprioli, R.M.3    Olafson, R.W.4
  • 86
    • 0026783494 scopus 로고
    • Transforming growth factor-β in leishmanial infection: A parasite escape mechanism
    • [83] Barral-Netto M, Barral A, Brownell CE, et al. Transforming growth factor-β in leishmanial infection: a parasite escape mechanism. Science 1992; 257: 545-548.
    • (1992) Science , vol.257 , pp. 545-548
    • Barral-Netto, M.1    Barral, A.2    Brownell, C.E.3
  • 87
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent Thelper 1 cell development in experimental leishmaniasis
    • [84] Scharton-Kersten T, Afonso LCC, Wysocka M, Trinchieri G, Scott P. IL-12 is required for natural killer cell activation and subsequent Thelper 1 cell development in experimental leishmaniasis. J Immunol 1995; 154: 5320-5330.
    • (1995) J Immunol , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 88
    • 0030021084 scopus 로고    scopus 로고
    • Leishmania promastigotes selectively inhibit interleukin-12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • [85] Carrera L, Gazzinelli RT, Badolato R, et al. Leishmania promastigotes selectively inhibit interleukin-12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J Exp Med 1996; 183: 515-526.
    • (1996) J Exp Med , vol.183 , pp. 515-526
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3
  • 89
    • 0031571866 scopus 로고    scopus 로고
    • Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells
    • [85a] Sartori A, Oliveira MAP, Scott P, Trinchieri G. Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells. J Immunol 1997; 159: 2849-2857.
    • (1997) J Immunol , vol.159 , pp. 2849-2857
    • Sartori, A.1    Oliveira, M.A.P.2    Scott, P.3    Trinchieri, G.4
  • 90
    • 0031028813 scopus 로고    scopus 로고
    • Leishmania aethiopica derived from diffuse leishmaniasis patients preferentially induce mRNA for interleukin 10, while those from localised leishmaniasis patients induce interferon-γ
    • [86] Akuffo H, Maasho K, Blostedt M, Höjeberg B, Britton S, Bakhiet M. Leishmania aethiopica derived from diffuse leishmaniasis patients preferentially induce mRNA for interleukin 10, while those from localised leishmaniasis patients induce interferon-γ. J Infect Dis 1997; 175: 737-741.
    • (1997) J Infect Dis , vol.175 , pp. 737-741
    • Akuffo, H.1    Maasho, K.2    Blostedt, M.3    Höjeberg, B.4    Britton, S.5    Bakhiet, M.6
  • 91
    • 0030022867 scopus 로고    scopus 로고
    • Differential expression of chemokines in skin lesions of patients with localized and diffuse American cutaneous leishmaniasis
    • [87] Ritter U, Moll H, Laskay T, et al. Differential expression of chemokines in skin lesions of patients with localized and diffuse American cutaneous leishmaniasis. J Infect Dis 1996; 173: 699-709.
    • (1996) J Infect Dis , vol.173 , pp. 699-709
    • Ritter, U.1    Moll, H.2    Laskay, T.3
  • 92
    • 0023106876 scopus 로고
    • Parasite accessory cell interactions in murine leishmaniasis. I. Evasion and stimulus-dependent suppression of the macrophage interleukin 1 response by Leishmania donovani
    • [88] Reiner NE. Parasite accessory cell interactions in murine leishmaniasis. I. Evasion and stimulus-dependent suppression of the macrophage interleukin 1 response by Leishmania donovani. J Immunol 1987; 138: 1919-1925.
    • (1987) J Immunol , vol.138 , pp. 1919-1925
    • Reiner, N.E.1
  • 93
    • 0025371391 scopus 로고
    • Modulation of in vitro monocyte cytokine responses to Leishmania donovani. Interferon-γ prevents parasite-induced inhibition of interleukin-1 production and primes monocytes to respond to Leishmania by producing both tumor necrosis factor-α and interleukin 1
    • [89] Reiner NE, Ng W, Wilson CB, McMaster WR, Burchett SK. Modulation of in vitro monocyte cytokine responses to Leishmania donovani. Interferon-γ prevents parasite-induced inhibition of interleukin-1 production and primes monocytes to respond to Leishmania by producing both tumor necrosis factor-α and interleukin 1. J Clin Invest 1990; 85: 1914-1924.
    • (1990) J Clin Invest , vol.85 , pp. 1914-1924
    • Reiner, N.E.1    Ng, W.2    Wilson, C.B.3    McMaster, W.R.4    Burchett, S.K.5
  • 94
    • 0024350240 scopus 로고
    • C-fos and tumor necrosis factor gene expression in Leishmania donovani-infected macrophages
    • [90] Descoteaux A, Matlashewski G. c-fos and tumor necrosis factor gene expression in Leishmania donovani-infected macrophages. Mol Cell Biol 1989; 9: 5223-5227.
    • (1989) Mol Cell Biol , vol.9 , pp. 5223-5227
    • Descoteaux, A.1    Matlashewski, G.2
  • 95
    • 0029908856 scopus 로고    scopus 로고
    • Lipophosphoglycan from Leishmania suppresses agonist-induced interleukin-1β gene expression in human monocytes via a unique promotor sequence
    • [91] Hatzigeorgiou DE, Geng J, Zhu B, et al. Lipophosphoglycan from Leishmania suppresses agonist-induced interleukin-1β gene expression in human monocytes via a unique promotor sequence. Proc Natl Acad Sci USA 1996; 93: 14708-14713.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14708-14713
    • Hatzigeorgiou, D.E.1    Geng, J.2    Zhu, B.3
  • 96
    • 0028158318 scopus 로고
    • Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection
    • [92] Reiner SL, Zheng S, Wang Z-E, Stowring L, Locksley RM. Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. J Exp Med 1994; 179: 447-456.
    • (1994) J Exp Med , vol.179 , pp. 447-456
    • Reiner, S.L.1    Zheng, S.2    Wang, Z.-E.3    Stowring, L.4    Locksley, R.M.5
  • 97
    • 0010549061 scopus 로고    scopus 로고
    • Flow cytometric analysis of cytokine production by inflammatory macrophages: Selective impairment of IL-12 induction in Leishmania infected cells
    • [93] Belkaid Y, Sacks D. Flow cytometric analysis of cytokine production by inflammatory macrophages: selective impairment of IL-12 induction in Leishmania infected cells. Abstr 28. Acta Parasitol Turc 1997; 21(Suppl): 23.
    • (1997) Acta Parasitol Turc , vol.21 , Issue.SUPPL. , pp. 23
    • Belkaid, Y.1    Sacks, D.2
  • 98
    • 0010623257 scopus 로고    scopus 로고
    • The role of nitric oxide in host-parasite interactions
    • Amsterdam
    • [94] Liew FY. The role of nitric oxide in host-parasite interactions. 13th European Immunology Meeting, Amsterdam, 1997.
    • (1997) 13th European Immunology Meeting
    • Liew, F.Y.1
  • 99
    • 0029670174 scopus 로고    scopus 로고
    • Local suppression of IFN-γ in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi
    • [95] Wilson ME, Sandor M, Blum AM, et al. Local suppression of IFN-γ in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J Immunol 1996; 156: 2231-2239.
    • (1996) J Immunol , vol.156 , pp. 2231-2239
    • Wilson, M.E.1    Sandor, M.2    Blum, A.M.3
  • 100
    • 0029091618 scopus 로고
    • Costimulation and the regulation of anti-microbial immunity
    • [96] Kaye PM. Costimulation and the regulation of anti-microbial immunity. Immunol Today 1995; 16: 423-427.
    • (1995) Immunol Today , vol.16 , pp. 423-427
    • Kaye, P.M.1
  • 101
    • 0028106942 scopus 로고
    • Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection
    • [97] Reiner NE. Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection. Immunol Today 1994; 15: 374-381.
    • (1994) Immunol Today , vol.15 , pp. 374-381
    • Reiner, N.E.1
  • 102
    • 0029155778 scopus 로고
    • Intracellular Leishmania amazonensis amastigotes internalize and degrade MHCclass II molecules of their host cells
    • [98] De Souza-Leao S, Lang T, Prina E, Hellio R, Antoine JC. Intracellular Leishmania amazonensis amastigotes internalize and degrade MHCclass II molecules of their host cells. J Cell Sci 1995; 108: 3219-3231.
    • (1995) J Cell Sci , vol.108 , pp. 3219-3231
    • De Souza-Leao, S.1    Lang, T.2    Prina, E.3    Hellio, R.4    Antoine, J.C.5
  • 103
    • 0028089711 scopus 로고
    • Deficient expression of co-stimulatory molecules on Leishmania-infected macrophages
    • [99] Kaye PM, Rogers NJ, Curry AJ, Scott JC. Deficient expression of co-stimulatory molecules on Leishmania-infected macrophages. Eur J Immunol 1994; 24: 2850-2854.
    • (1994) Eur J Immunol , vol.24 , pp. 2850-2854
    • Kaye, P.M.1    Rogers, N.J.2    Curry, A.J.3    Scott, J.C.4
  • 104
    • 0029083603 scopus 로고
    • Macrophage-T cell interaction in experimental visceral leishmaniasis: Failure to express costimulatory molecules on Leishmania-infected macrophages and its implications in the suppression of cell-mediated immunity
    • [100] Saha B, Das G, Vohra H, Ganguly NK, Mishra GC. Macrophage-T cell interaction in experimental visceral leishmaniasis: failure to express costimulatory molecules on Leishmania-infected macrophages and its implications in the suppression of cell-mediated immunity. Eur J Immunol 1995; 25: 2492-2498.
    • (1995) Eur J Immunol , vol.25 , pp. 2492-2498
    • Saha, B.1    Das, G.2    Vohra, H.3    Ganguly, N.K.4    Mishra, G.C.5
  • 105
    • 0027488625 scopus 로고
    • Helper T cells without CD4: Control of leishmaniasis in CD4-deficient mice
    • [101] Locksley RM, Reiner SL, Hatam F, Littman DR, Killeen N. Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice. Science 1993; 261: 1448-1451.
    • (1993) Science , vol.261 , pp. 1448-1451
    • Locksley, R.M.1    Reiner, S.L.2    Hatam, F.3    Littman, D.R.4    Killeen, N.5
  • 106
    • 0029840937 scopus 로고    scopus 로고
    • Antigen presentation by Leishmania mexicana-infected macrophages: Activation of helper T cells by a model parasite antigen secreted in to the parasitophorous vacuole or expressed on the amastigote surface
    • [102] Wolfram M, Fuchs M, Stierhof Y-D, Overath P. Antigen presentation by Leishmania mexicana-infected macrophages: activation of helper T cells by a model parasite antigen secreted in to the parasitophorous vacuole or expressed on the amastigote surface. Eur J Immunol 1996; 26: 3153-3162.
    • (1996) Eur J Immunol , vol.26 , pp. 3153-3162
    • Wolfram, M.1    Fuchs, M.2    Stierhof, Y.-D.3    Overath, P.4
  • 107
    • 0030004213 scopus 로고    scopus 로고
    • Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages
    • [103] Prina E, Lang T, Glaichenhaus N, Antoine J-C. Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages. J Immunol 1996; 156: 4318-4327.
    • (1996) J Immunol , vol.156 , pp. 4318-4327
    • Prina, E.1    Lang, T.2    Glaichenhaus, N.3    Antoine, J.-C.4
  • 108
    • 0029799686 scopus 로고    scopus 로고
    • Leishmania-infected macrophages sequester endogenously synthesized parasite antigens from presentation to CD4+ T cells
    • [104] Kima PE, Soong L, Chicharro C, Ruddle NH, McMahon-Pratt D. Leishmania-infected macrophages sequester endogenously synthesized parasite antigens from presentation to CD4+ T cells. Eur J Immunol 1996; 26: 3163-3169.
    • (1996) Eur J Immunol , vol.26 , pp. 3163-3169
    • Kima, P.E.1    Soong, L.2    Chicharro, C.3    Ruddle, N.H.4    McMahon-Pratt, D.5
  • 109
    • 0002467608 scopus 로고    scopus 로고
    • The impact of the type 1 and type 2 T helper cell concept on novel vaccine design with emphasis on protection against Leishmania parasites
    • Kaufmann SHE, editor. Berlin: Walter de Gruyter
    • [105] Bogdan C, Röllinghoff M. The impact of the type 1 and type 2 T helper cell concept on novel vaccine design with emphasis on protection against Leishmania parasites. In: Kaufmann SHE, editor. Concepts in vaccine development. Berlin: Walter de Gruyter, 1996;143-180.
    • (1996) Concepts in Vaccine Development , pp. 143-180
    • Bogdan, C.1    Röllinghoff, M.2
  • 110
    • 0001123104 scopus 로고    scopus 로고
    • IL-4 rapidly produced by Vβ4Vα8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice
    • [106] Launois P, Maillard I, Pingel S, et al. IL-4 rapidly produced by Vβ4Vα8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity 1997; 6: 541-549.
    • (1997) Immunity , vol.6 , pp. 541-549
    • Launois, P.1    Maillard, I.2    Pingel, S.3
  • 111
    • 0029802971 scopus 로고    scopus 로고
    • Resistance to Leishmania major in mice
    • [107] Demant P, Lipoldova M, Svobodova M. Resistance to Leishmania major in mice. Science 1996; 274: 1392.
    • (1996) Science , vol.274 , pp. 1392
    • Demant, P.1    Lipoldova, M.2    Svobodova, M.3
  • 112
    • 0029861329 scopus 로고    scopus 로고
    • Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses
    • [108] Gorham JD, Güler ML, Steen RG, et al. Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc Natl Acad Sci USA 1996; 93: 12467-12472.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12467-12472
    • Gorham, J.D.1    Güler, M.L.2    Steen, R.G.3
  • 113
    • 0030612781 scopus 로고    scopus 로고
    • Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice
    • [109] Beebe AM, Mauze S, Schork NJ, Coffman RL. Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. Immunity 1997; 6: 551-557.
    • (1997) Immunity , vol.6 , pp. 551-557
    • Beebe, A.M.1    Mauze, S.2    Schork, N.J.3    Coffman, R.L.4
  • 114
    • 0030923103 scopus 로고    scopus 로고
    • Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9
    • [110] Roberts LJ, Baldwin TM, Curtis JM, Handman E, Foote SJ. Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9. J Exp Med 1997; 185: 1705-1710.
    • (1997) J Exp Med , vol.185 , pp. 1705-1710
    • Roberts, L.J.1    Baldwin, T.M.2    Curtis, J.M.3    Handman, E.4    Foote, S.J.5
  • 115
    • 0029083388 scopus 로고
    • Sandfly vector saliva selectively modulates macrophage functions that inhibit killing of Leishmania major and nitric oxide production
    • [111] Hall LR, Titus RG. Sandfly vector saliva selectively modulates macrophage functions that inhibit killing of Leishmania major and nitric oxide production. J Immunol 1995; 155: 3501-3506.
    • (1995) J Immunol , vol.155 , pp. 3501-3506
    • Hall, L.R.1    Titus, R.G.2
  • 116
    • 0000313523 scopus 로고    scopus 로고
    • Immunomodulatory properties of maxadilan, a peptide derived from sandfly saliva
    • [112] David J, Soares N, Satoskar A, et al. Immunomodulatory properties of maxadilan, a peptide derived from sandfly saliva. Abstr 364. Acta Parasitol Turc 1997; 21(Suppl): 174.
    • (1997) Acta Parasitol Turc , vol.21 , Issue.SUPPL. , pp. 174
    • David, J.1    Soares, N.2    Satoskar, A.3
  • 117
    • 0010552353 scopus 로고    scopus 로고
    • Sandfly saliva and leishmaniosis
    • [113] Warburg A., Waitumbi J. Sandfly saliva and leishmaniosis. Abstr 122. Acta Parasitol Turc 1997; 21(Suppl): 67.
    • (1997) Acta Parasitol Turc , vol.21 , Issue.SUPPL. , pp. 67
    • Warburg, A.1    Waitumbi, J.2


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