Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats

Journal of Applied Physiology

Volumn 84, Issue 4, 1998, Pages 1138-1143

  Lai, C J ^a   Kou, Y R ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Airway irritation; Carbon dioxide; Carbonic anhydrase; Hydrogen ion; Vagal sensory receptors

Indexed keywords

ACETAZOLAMIDE; BRONCHODILATING AGENT; CARBON DIOXIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; ISOPRENALINE; PROTON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BREATHING; CONTROLLED STUDY; FEMALE; HYPERCAPNIA; LUNG BURN; LUNG MECHANICS; LUNG PRESSURE; LUNG RECEPTOR; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SENSORY RECEPTOR; SMOKE; VAGUS NERVE; WOOD;

EID: 0031940093     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.4.1138     Document Type: Article

References (30)

1. Bartlett, D., Jr., and G. Sant'Ambrogio. Effects of local and systemic hypercapnia on the discharge of stretch receptors in the airways of the dog. Respir. Physiol. 26: 91-99, 1976.
2. Bergren, D. R., and D. F. Peterson. Identification of vagal sensory receptors in the rat lung: are there subtypes of slowly adapting receptors? J. Physiol. (Lond.) 464: 681-698, 1993.
3. Bradley, G. W., M. I. M. Noble, and D. Trenchard. The direct effect on pulmonary stretch receptor discharge produced by changing lung carbon dioxide concentration in dogs on cardiopulmonary bypass and its action on breathing. J. Physiol. (Lond.) 261: 359-373, 1976.
4. 2 and pH on neuronal membranes. Federation Proc. 31: 1399-1403, 1972.
5. Cammer, W., and F. A. Tansey. Immunocytochemical localization of carbonic anhydrase in myelinated fibers in peripheral nerves of rat and mouse. J. Histochem. Cytochem. 35: 865-870, 1987.
6. Clark, F. J., and C. von Euler. On the regulation of depth and rate of breathing. J. Physiol. (Lond.) 222: 267-295, 1972.
7. 2 and carbonic anhydrase inhibition. Respir. Physiol. 104: 53-61, 1996.
8. Coleridge, H. M., and J. C. G. Coleridge. Reflexes evoked from tracheobronchial tree and lungs. In: Handbook of Physiology. The Respiratory System. Control of Breathing. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. II, pt. 1, chapt. 12, p. 395-429.
9. 2 on afferent vagal endings in the canine lung. Respir. Physiol. 34: 135-151, 1978.
10. 2 on slowly adapting pulmonary stretch receptors. J. Appl. Physiol. 60: 2048-2055, 1986.
11. Haselton, J. R., A. Y. Reynolds, and H. D. Schultz. Vagal neuroeffector mechanisms affecting transpulmonary pressure in the intact rat. J. Appl. Physiol. 79: 1233-1241, 1995.
12. 2 changes on lung mechanics in dogs. J. Appl. Physiol. 38: 603-607, 1975.
13. Kou, Y. R., and C. J. Lai. Reflex changes in breathing pattern evoked by inhalation of wood smoke in rats. J. Appl. Physiol. 76: 2333-2341, 1994.
14. Kou, Y. R., C.-Y. Wang, and C. J. Lai. Role of vagal afferents in the acute ventilatory responses to inhaled wood smoke in rats. J. Appl. Physiol. 78: 2070-2078, 1995.
15. 2 sensitive vagal afferents in the cat lung. Respir. Physiol. 27: 347-355, 1976.
16. Lai, C. J., T. H. Hsu, and Y. R. Kou. Role of hydroxyl radical in the activation of vagal bronchopulmonary afferents by inhaled wood smoke in rats (Abstract). FASEB J. 10: A638, 1996.
17. Lai, C. J., and Y. R. Kou. Stimulation of pulmonary vagal C fibers by inhaled wood smoke in rats. J. Appl. Physiol. 84: 30-36, 1998.
18. Larson, T. V., and J. Q. Koenig. Wood smoke: emissions and noncancer respiratory effects. Annu. Rev. Public Health 15: 133-156, 1994.
19. Lee, L.-Y., Y. R. Kou, D. T. Frazier, E. R. Beck, T. E. Pisarri, H. M. Coleridge, and J. C. G. Coleridge. Stimulation of vagal pulmonary C-fibers by a single breath of cigarette smoke in dogs. J. Appl. Physiol. 66: 2032-2038, 1989.
20. Maren, T. H. Use of inhibitors in physiological studies of carbonic anhydrase. Am. J. Physiol. 232 (Renal Fluid Electrolyte Physiol. 1): F291-F297, 1977.
21. 2 inhalation on slowly adapting pulmonary stretch receptors in the anesthetized rabbit. J. Pharmacol. Exp. Ther. 279: 402-409, 1996.
22. 2 and airway pressure on phrenic activity and pulmonary stretch receptor discharge in dogs. Respir. Physiol. 40: 29-48, 1980.
23. 2 upon discharge from slowly adapting stretch receptors in the lungs of rabbits. Respir. Physiol. 16: 197-212, 1972.
24. Pack, A. I. Sensory inputs to the medulla. Annu. Rev. Physiol. 43: 73-90, 1981.
25. Ravi, K. Effects of carbon dioxide on the activity of slowly and rapidly adapting pulmonary stretch receptors in cats. J. Auton. Nerv. Syst. 12: 267-277, 1985.
26. Sant'Ambrogio, G. Information arising from the tracheobronchial tree of mammals. Physiol. Rev. 62: 531-569, 1982.
27. Sant'Ambrogio, G., G. Miserocchi, and J. Mortola. Transient responses of pulmonary stretch receptors in the dog to inhalation of carbon dioxide. Respir. Physiol. 22: 191-197, 1974.
28. CO2 on the slowly adapting pulmonary stretch receptor. Am. J. Physiol. 222: 68-72, 1972.
29. Szabolcs, M. J., M. Kopp, and G. E. Schaden. Carbonic anhydrase activity in the peripheral nervous system of rat: the enzyme as a marker for muscle afferents. Brain Res. 492: 129-138, 1989.
30. Widdicombe, J. G. Receptors in the trachea and bronchi of the cats. J. Physiol. (Lond.) 123: 71-104, 1954.