Catechol estrogens as inhibitors of leukotriene synthesis

Biochemical Pharmacology

Volumn 55, Issue 1, 1998, Pages 101-104

  Alanko, Juha ^a   Sievi, Eeva ^d   Lähteenmäki, Tuula ^d   Mucha, István ^b   Vapaatalo, Heikki ^d   Parantainen, Jouko ^c  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b Institute of Isotopes   (Hungary)

^c Oy Leiras Finland Ab   (Finland)

^d NONE

Author keywords

Estradiol; Estrogen; Leukotriene; Prostaglandin; Thromboxane

Indexed keywords

2 HYDROXYESTRADIOL; 2 HYDROXYESTRONE; 4 HYDROXYESTRADIOL; 4 HYDROXYESTRONE; CATECHOL ESTROGEN; ESTRADIOL; ESTROGEN; LEUKOTRIENE; LEUKOTRIENE E4; PROSTAGLANDIN; PROSTAGLANDIN E2; THROMBOXANE; THROMBOXANE B2; UNCLASSIFIED DRUG;

ARACHIDONIC ACID METABOLISM; ARTICLE; ATHEROSCLEROSIS; BLOOD; CONTROLLED STUDY; DOSE RESPONSE; ESTRADIOL BLOOD LEVEL; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MENOPAUSE; NORMAL HUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS;

ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; CALCIMYCIN; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ENZYME INHIBITORS; ESTRADIOL; ESTROGENS, CATECHOL; HUMANS; IONOPHORES; LEUKOTRIENE E4; LEUKOTRIENES; LIPOXYGENASE INHIBITORS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; STIMULATION, CHEMICAL; THROMBOXANE B2;

EID: 0031938660     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00398-5     Document Type: Article

References (24)

1. 1. Stampfer MJ, Colditz GA, Willet WC, Manson JE, Rosner B, Speizer FE and Hennekens CH, Postmenopausal estrogen therapy and cardiovascular disease. N Engl J Med 325: 756-762, 1991.
2. 2. Rosano GMC, Sarrel PM, Poole-Wilson PA and Collins P, Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet 342: 133-136, 1993.
3. 3. Sack MN, Rader DJ and Cannon III RO, Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women. Lancet 343: 269-270, 1994.
4. 4. Nakano M, Sugioka K, Naito I, Takekoshi S and Niki E, Novel and potent biological antioxidants on membrane phospholipid peroxidation; 2-hydroxy estrone and 2-hydroxy estradiol. Biochem Biophys Res Comm 142: 919-924, 1987.
5. 5. Kelly RW and Abel MH, Catechol oestrogens stimulate and direct prostaglandin synthesis. Prostaglandins 20: 613-626, 1980.
6. 6. Pakrasi PL and Dey SK, Catechol estrogens stimulate synthesis of prostaglandins in the preimplantation rabbit blastocyst and endometrium. Biol Reprod 29: 347-354, 1983.
7. 7. Franchi AM, Gimeno AL and Gimeno MAF, Influences of estradiol and of catechol and non-catechol estrogens on the output of prostaglandins in uteri from spayed rats. Prostaglandins Leukotr Essential Fatty Acids 36: 25-29, 1989.
8. 8. Rosenkrans Jr CF, Paria BC, Davis DL and Milligen G, Synthesis of prostaglandins by pig blastocysts cultured in medium containing estradiol or catechol estrogens. Prostaglandins 43: 309-319, 1992.
9. 9. Zhang Z and Davis DL, Cell-type specific responses in prostaglandin secretion by glandular and stromal cells from pig endometrium treated with catecholestrogens, methoxyestrogens and progesterone. Prostaglandins 44: 53-64, 1992.
10. 10. Alanko J, Riutta A, Mucha I, Vapaatalo H and Metsä-Ketelä T, Modulation of arachidonic acid metabolism by phenols: relation to positions of hydroxyl groups and peroxyl radical scavenging properties. Free Rad Biol Med 14: 19-25, 1993.
11. 2 synthesis in A23187-stimulated human whole blood. Prostaglandins 42: 279-287, 1991.
12. 12. Alanko J, Riutta A, Mucha I, Kerttula T, Kaukinen S, Vapaatalo H, Metsä-Ketelä T and Seppälä E, Adrenaline stimulates thromboxane and inhibits leukotriene synthesis in man. Eicosanoids 5: 169-175, 1992.
13. 13. Nishizawa Y, Nishii K, Nishizawa Y, Koga M, Kishimoto S, Matsumoto K and Sato B, Effects of estrogen on cell proliferation and leukotriene formation in transformed mouse Leydig cells cultured under serum-free conditions. Cancer Res 50: 3866-3871, 1990.
14. 17-sulfoconjugated catechol estrogens upon lipid peroxidation of rat liver microsomes. Biol Pharm Bull 18: 1120-1125, 1995.
15. 15. Ruiz-Larrea MB, Leal AM, Lacort M and de Groot H, Antioxidant effects of estradiol and 2-hydroxyestradiol on iron-induced lipid peroxidation of rat liver microsomes. Steroids 59: 383-388, 1994.
16. 16. Parantainen J, Alanko J, Moilanen E, Metsä-Ketelä T, Asmawi MZ and Vapaatalo H, Catecholamines inhibit leukotriene formation and decrease leukotriene/prostaglandin ratio. Biochem Pharmacol 40: 961-966, 1990.
17. 17. Riutta A, Alanko J, Mucha I and Vapaatalo H, Effects of trolox C and sin-1 on arachidonic acid metabolism and on cyclic GMP formation in A23187-stimulated human polymorphonuclear leukocytes. Eur J Pharmacol 262: 217-222, 1994.
18. 18. Kemal C, Louis-Flamberg P, Krupinski-Olsen R and Shorter AL, Reductive inactivation of soybean lipoxygenase 1 by catechols: a possible mechanism for regulation of lipoxygenase activity. Biochemistry 26; 7064-7072, 1987.
19. 19. Hemler ME and Lands WEM, Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis. J Biol Chem 255: 6253-6261, 1980.
20. 20. Carry M, Korley V, Willerson JT, Weigelt L, Ford-Hutchinson AW and Tagari P, Increased urinary leukotriene excretion in patients with cardiac ischemia. In vivo evidence for 5-lipoxygenase activation. Circulation 85: 230-236, 1992.
21. 21. Rossi P, Kuukasjärvi P, Salenius JP, Tarkka M and Alanko J, Leukotriene production is increased in lower limb ischemia. Int J Angiol 6: 89-90, 1997.
22. 4. Cardioscience 4: 47-54, 1993.
23. 23. Meghji S, Sandy JR, Scutt AM, Harvey W and Harris M, Stimulation of bone resorption by lipoxygenase metabolites of arachidonic acid. Prostaglandins 36: 139-149, 1988.
24. 24. Ball P and Knuppen R, Formation, metabolism, and physiological importance of catecholestrogens. Am J Obstet Gynecol 163: 2163-2170, 1990.