Correlates of photoreceptor rescue by transplantation of human fetal RPE in the RCS rat

Experimental Neurology

Volumn 149, Issue 1, 1998, Pages 151-160

  Little, Caroline W ^a   Cox, Christopher ^a   Wyatt, Jeffrey ^a   Del Cerro, Coca ^a   Del Cerro, Manuel ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Human RPE; Photoreceptor rescue; RCS rat; Transplantation; Vision

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FETAL TISSUE TRANSPLANTATION; HUMAN; HUMAN CELL; LIGHT; MAZE TEST; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RAT; SWIMMING; VISION;

EID: 0031938616     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6642     Document Type: Article

References (33)

1. Bourne M. C., Campell D. A., Tansley K. Hereditary degeneration of the rat retina. Br. J. Ophthalmol. 22:1938;613-623.
2. Bourne M. C., Gruneberg H. Degeneration of the retina and cataract, a new recesive gene in the rat (Ratus norvegicus. J. Hered. 30:1939;131-136.
3. Dowling J. E., Sidman R. L. Inherited retinal dystrophy in the rat. J. Cell Biol. 14:1996;73-109.
4. Heron W. L., Riegel B. W., Meyers O. E., Rubin M. L. Retinal dystrophy in the rat: A pigment epithelial disease. Invest. Ophthalmol. Vis. Sci. 8:1969;595-604.
5. Bok D., Hall M. O. The role of the pigment epithelium in the etiology of inherited retinal dystrophy in the rat. J. Cell Biol. 49:1971;664-682.
6. Li L., Turner J. E. Inherited retinal dystrophy in the RCS rat: Prevention of photoreceptor degeneration by pigment epithelial cell transplantation. Exp. Eye Res. 47:1988;911-917.
7. Li L., Turner J. E. Transplantation of retinal pigment epithelial cells to immature and adult rat hosts: Short- and long-term survival characteristics. Exp. Eye Res. 47:1988;771-785.
8. Gouras P., Lopez R., Kjeldbye H., Sullivan B., Britis M. Transplantation of retinal epithelium prevents photoreceptor degeneration in the RCS rat. Inherited and Environmentally Induced Retinal Degenerations. 1989;A. R. Liss, New York. p. 659-671.
9. Lopez R., Gouras P., Kjeldbye H. Transplanted retinal pigment epithelium modifies the retinal degeneration in the RCS rat. Invest. Ophthalmol. Vis. Sci. 30:1989;586-588.
10. Jiang L. Q., Hamasaki D. Corneal electroretinographic function rescued by normal retinal pigment epithelial grafts in retinal degenerative Royal College of Surgeons rats. Invest. Ophthalmol. Vis. Sci. 35:1994;4300-4309.
11. Little C. W., Castillo B., DiLoreto D. A., Cox C., Wyatt J., del Cerro C., del Cerro M. Transplantation of human fetal retinal pigment epithelium rescues photoreceptor cells from degeneration in the Royal College of Surgeons rat retina. Invest. Ophthalmol. Vis. Sci. 37:1996;204-211.
12. del Cerro M., Castillo B. V., White R. Jr. Juvenile human RPE graft rescues photoreceptor cells in dystrophic RCS rats. Invest. Ophthalmol. Vis. Sci. 37:1996;S94.
13. Castillo B. V. Jr., del Cerro M., White R. M. Efficacy of non-fetal human RPE for photoreceptor rescue: A study in dystrophic RCS rats. Exp. Neurol. 146:1997;1-9.
14. Perlman I. Dark-adaptation in abnormal (RCS) rats studied electroretinographically. J. Physiol. 278:1978;161-175.
15. Trejo L. J., Cicerone C. M. Retinal sensitivity measured by the pupillary light reflex in RCS and albino rats. Vis Res. 22:1982;1163-1171.
16. Kovalesky G., DiLoreto D. Jr., Wyatt J., del Cerro C., Cox C., del Cerro M. The intensity of the pupillary light reflex does not correlate with the number of retinal photoreceptor cells. Exp. Neurol. 133:1995;43-49.
17. Kaitz M. The effect of light on brightness perception in rats with retinal dystrophy. Vis. Res. 16:1976;141-148.
18. LaVail M. M., Sidman M., Rausin R., Sidman R. L. Discrimination of light intensity by rats with inherited retinal degeneration: A behavioral and cytological study. Vis. Res. 14:1974;693-702.
19. Wecker J. R., Ison J. R. Visual function measured by reflex modification in rats with inherited retinal dystrophy. Behav. Neurosci. 100:1985;679-684.
20. DiLoreto D. Jr., del Cerro M., Reddy S. V., Janardhan S., Cox C., Wyatt J., Balkema G. E. Water escape performance of adult RCS dystrophic and congenic rats: A functional and histomorphometric study. Brain Res. 717:1996;165-172.
21. DiLoreto D. Jr., del Cerro C., Lazar E., Cox C., del Cerro M. Storage of human fetal retina in Optisol prior to subretinal. Brain Res. Cell Transpl. 5:1996;553-561.
22. Castillo B. Jr., Little C., del Cerro C., del Cerro M. An improved method of isolating human fetal RPE. Curr. Eye Res. 14:1995;677-683.
23. Lazar E. S., del Cerro M. A new procedure for multiple intraretinal transplantation into mammalian eyes. J. Neurosci. Methods. 43:1992;157-169.
24. Triarhou L. C., del Cerro M. Colloidal carbon as a multilevel marker for experimental lesions. Experientia. 41:1985;620-621.
25. DiLoreto D., Cox C., Grover D. A. The influences of age, retinal topography, and gender on retinal degeneration in the Fischer 344 rat. Brain Res. 647:1994;181-191.
26. del Cerro M., Notter M. F. D., del Cerro C. Intraretinal transplantation for rod-cone replacement in light-damaged retinas. J. Neurol. Transplant. 1:1989;1-10.
27. del Cerro M., Ison J. R., Bowen G. P., Lazar E., del Cerro C. Intraretinal grafting restores visual function in light-blinded rats. NeuroReports. 2:1991;529-532.
28. Brownlee K. A. Statistical Theory and Methodology in Science and Engineering. 1960;Wiley, New York. p. 570.
29. Crowder M. J., Hand D. J. Analysis of Reported Measures. 1990;Chapman & Hall, London.
30. Armitage J. M., Kormos R. L., Stuart R. S. Posttransplant lymphoproliferative disease in thoracic organ transplant patients: Ten years of cyclosporine-based immunosuppression. J. Heart Lung Transplant. 10:1991;877-886.
31. McNally P. G., Feehally J. Pathophysiology of cyclosporin A nephrotoxicity: Experimental and clinical observations. Nephrol. Dial. Transplant. 7:1992;791-804.
32. Rolls K. A., Phillips P. A. A., Aldred K., Hardy K. J. Vasoconstrictor responses to components of the renin-angiotensin system in cyclosporin-induced hypertension in the rat. Clin. Exp. Pharm. Physiol. 21:1994;227-230.
33. Vilardell J., Oppenheimer F., Talbot-Wright R. Increased risk of malignant tumors in renal transplant recipients receiving cyclosporine. Transplant. Proc. 24:1992;1948.