Brain 5-HT neurotransmission during paroxetine treatment

British Journal of Psychiatry

Volumn 172, Issue JAN., 1998, Pages 49-52

  Sargent, P A ^a   Williamson, D J ^a   Cowen, P J ^a  

^a WARNEFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; CYPROHEPTADINE; HYDROCORTISONE; PAROXETINE; SEROTONIN 2 AGONIST; SEROTONIN 2 ANTAGONIST; SEROTONIN UPTAKE INHIBITOR;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEPRESSION; FEMALE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; MALE; MENTAL DISEASE; NEUROTRANSMISSION; PSYCHOPHARMACOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SEROTONINERGIC TRANSMISSION; SINGLE BLIND PROCEDURE;

EID: 0031938455     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.172.1.49     Document Type: Article

References (21)

1. Anderson, I. M. & Tomenson, B. M. (1994) The efficacy of selective serotonin re-uptake inhibitors in depression: a meta-analysis of studies against tricyclic antidepressants. Journal of Psychopharmacology, 8, 238-249.
2. Arnott, S. & Nutt, D. (1994) Successful treatment of fluvoxamine-induced anorgasmia by cyproheptadine. British Journal of Psychiatry, 164, 838-839.
3. Blier, P. & de Montigny, C. (1994) Current advances and trends in the treatment of depression. Trends in Pharmacological Sciences, 15, 220-226.
4. Conover, W. J. & Iman, R. L. (1981) Rank transformations as a bridge between parametric and non-parametric statistics. American Statistician, 35, 121-129.
5. Cowen, P. J. (1993) Serotonin receptor subtypes in depression: evidence from studies in neuroendocrine regulation. Clinical Neuropharmacology, 16 (suppl. 3), S6-S18.
6. Deakin, J. F. W. & Graeff, F. G. (1791) 5-HT and mechanisms of defence. Journal of Psychopharmacology, 5, 305-315.
7. Erzegovesi, S., Ronchi, P. & Smeraldi, E. (1991) 5-HT-2 receptor and fluvoxamine effect in obsessive compulsive disorder. Human Psychopharmacology, 7, 287-289.
8. Fuller, R. W. (1981) Serotonergic stimulation of pituitary-adrenocortical function in rats. Neuroendocrinology 32, 118-127.
9. 2 receptors. European Journal of Pharmacology, 179, 103-109.
10. _, _ & Sharp, T. (1992) Effect of 5-hydroxy-L-tryptophan on the release of 5-HT in rat hypothalamus in vivo as measured by microdialysis. Neuropharmocology, 31, 9-14.
11. 1C receptors in the antiserotonergic properties of some antidepressant drugs. European Journal of Pharmacology, 231, 223-229.
12. Johnson, A. M. (1991) The comparative pharmacological properties of selective serotonin re-uptake inhibitors in animals. In Selective Serotonin Re-uptake Inhibitors (eds J. P. Feighner & W. F. Boyer), pp. 37-70. Chichester: Wiley.
13. Katsuda, Y., Walsh, A. E. S., Ware, C. J., et al (1993) Meta-chlorophenylpiperazine decreases slow-wave sleep in humans. Biological Psychiatry, 33, 49-51.
14. Lee, M. A., Nash, J. F., Barnes, M., et al (1991) Inhibitory effect of ritanserin on the 5-hydroxy tryptophan-mediated cortisol, ACTH and prolactin secretion in humans. Psychopharmacology, 103, 258-264.
15. Meltzer, H. Y., Lowy, M., Robertson, A., et al (1984) Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. 3. Effects of antidepressants and lithium carbonate. Archives of General Psychiatry, 41, 391-397.
16. _ & Maes, M. (1994) Effects of pindolol on the L-5-HTP-induced increase in plasma prolactin and cortisol concentrations in man. Psychopharmacology 114, 635-643.
17. Piccinelli, M., Pini, S., Bellantuono, C., et al (1995) Efficacy of drug treatment in obsessive-compulsive disorder: a meta-analy tic review. British Journal of Psychiatry, 164, 424-443.
18. Preskorn, S. H. (1995) Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline and venlafaxine. Journal of Clinical Psychiatry, 54 (suppl. 6), 12-21.
19. Price, L. H., Charney, D. S., Delgada, P. L., et al (1989) Effects of desipramine and fluvoxamine treatment on the prolactin response to tryptophan: serotonergic function and the mechanism of antidepressant action. Archives of General Psychiatry, 46, 625-631.
20. Thompson, C., Mezey, G., Corn, T., et al (1985) The effect of desipramine on melatonin and cortisol secretion in depressed and normal subjects. British Journal of Psychiatry, 147, 389-393.
21. Yatham, L. N. & Steiner, M. (1993) Neuroendocrine probes of serotonergic function: a critical review. Life Sciences, 53, 447-463.