The C-kit receptor and its possible signaling transduction pathway in mouse spermatozoa

Molecular Reproduction and Development

Volumn 49, Issue 3, 1998, Pages 317-326

  Feng, Huailiang ^a   Sandlow, Jay I ^a   Sandra, Alexander ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Acrosome reaction; C kit receptor; Mouse; Signal transduction; Sperm; Stem cell factor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIMYCIN; CALCIUM CHANNEL; IMMUNOGLOBULIN G; STEM CELL FACTOR; VERAPAMIL; WORTMANNIN;

ACROSOME REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHOSPHORYLATION; DNA DETERMINATION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SPERMATOZOON; SPERMATOZOON CAPACITATION; STEM CELL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; ENZYME INHIBITORS; IMMUNOENZYME TECHNIQUES; ISOENZYMES; MALE; MICE; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-KIT; RABBITS; RATS; SIGNAL TRANSDUCTION; SPERMATOZOA; STEM CELL FACTOR; TYROSINE;

ANIMALIA;

EID: 0031938242     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2795(199803)49:3<317::AID-MRD12>3.0.CO;2-T     Document Type: Article

References (59)

1. Albanesi C, Geremia R, Giorgio M, Dolci S, Sette C, Rossi P (1996): A cell- and developmental stage-specific promoter drives the expression of truncated c-kit protein during mouse spermatid elogation. Development 122:1291-1302.
2. Anderson DM, Lyman SD, Baird A, Wignall JM, Eisenman J, Rauch C, March CJ, Boswell HS, Gimpel SD, Gasman D, Williams DE (1990): Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms. Cell 63:235-243.
3. Arons DA, Tong HB, Holt G, Poirier GR (1991): Acrosome reaction induced by immunoaggregation of a proteinase inhibitor bound to the murine sperm head. Mol Reprod Dev 30:258-264.
4. Besmer P, Snyder HW, Murphy JE, Hardy WD, Parodi A (1983): The perodi-irgens feline sarcoma virus have homologous oncogenes, but in different contents of the viral genome. J Virol 46:606-613.
5. Besmer P, Murphy PC, George PC, Qiu F, Bergold PT, Lederman L, Snyder HW, Brodeur D, Zuckerman EE, Hardy WD (1986): A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase family. Nature 320:415-121.
6. Blechman JM, Lev S, Givol D, Yarden Y (1993): Structure-function analysis of the kit receptor for the steel factor. Stem Cells 11:12-21.
7. Blume-Jensen P, Wernstedt C, Heldin CH, Rönnstran L (1995): Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor reactor in vitro and intact cells. J Biol Chem 270:14192-14200.
8. Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A (1988): The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature 335:88-89.
9. Dym M, Jia MC, Dirrami G, Price JM, Rabin SJ, Mocchetti I, Ravindranath N (1995): Expression of c-kit receptor and its autophosphorylation in immature rat type A spermatogonia. Biol Reprod 52:8-19.
10. Feng HL (1994): Fertilization in mammalian. In HL Feng (ed): "The Embryo Technology in Mammals." Jilin, China: Changchun Publishing House, pp 57-84.
11. Feng HL, Qin PC, Chen DY (1993a): Ionic changes of pig spermatozoa in pre- and post-capacitation in vitro. Acta Zool Sinica 39:326-333.
12. Feng HL, Yang QZ, Qin PC (1993b): Changes of elements in cattle sperm of pre- and post-capacitation in vitro. Sci Agri Sinica 26:63-69.
13. Feng HL, Sandlow JI, Sandra A (1997a): Expression and function of the c-kit proto-oncogene protein in mouse sperm. Biol Reprod 57:194-203.
14. Feng HL, Sandlow JI, Sandra A (1997b): Localization of intracellular calcium and its possible role during spermatogeneis and sperm capacitation in the hamster. Theriogenology 47:256 (abstract).
15. Fisher HM, Barratt CLR, Looke ID, Moore HDM (1996): Phosphoionositide 3-kinase is involved in the induction of the human sperm acrosome reaction downstream of tyrosine phosphorylation. Biol Reprod 54(suppl):140.
16. d mutant. Cell 64:1025-1035.
17. Geissler EN, Ryan MA, Housman DE (1988): The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene. Cell 55:185-192.
18. Horie K, Takakura, Taii S, Narimoto K, Noda Y, Wishikawa S, Nakayama H, Fujita J, Mori T (1991): The expression of c-kit protein during oogenesis and early embryonic development. Biol Reprod 45:547-552.
19. Huang E, Nocka K, Beier DR, Chu TY, Buck J, Lahm HW, Wellner D, Leder P, Besmer P (1990): The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63:225-233.
20. Huang EJ, Nocka KH, Buck J, Besmer P (1992): Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2. Mol Cell Biol 3:349-362.
21. Kazlauskas A, Ellis C, Pawson T, Cooper JA (1990): Binding of GAP to activated PDGF receptors. Science 247:1578-1581.
22. Kinashi T, Escobedo J, Williams LT, Takatsu K, Springer TA (1995): Receptor tyrosine kinase stimulate cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase Cγ1 pathways. Blood 86:2086-2090.
23. Lev S, Givol D, Yarden Y (1991): A specific combination by the kit-encoded receptor. EMBO J 10:647-654.
24. Llanos MN, Anabalon MC (1996): Studies related to progesterone-induced hamster sperm acrosome reaction. Mol Reprod Dev 45:313-319.
25. Majumder SK, Brown K, Qiu F, Besmer P (1988): C-kit protein, a transmembrane kinase identification in tissues and characterization. MoI Cell Biol 8:4896-4903.
26. Manova K, Nocka K, Besmer P, Bachvarova RF (1990): Gonadal expression of c-kit encoded at the W locus of mice. Development 110:1057-1069.
27. Manova K, Huang EJ, Angeles M, Deleon V, Sanchez S, Pronovost SM, Besmer P, Bachvarova RF (1993): The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia. Dev Biol 157:85-99.
28. Moller CC, Bleil JD, Kinloch RA, Wassarman PM (1990): Structural and functional relationships between mouse and hamster zona pellucrda glycoproteins. Dev Biol 137:276-286.
29. Motro B, Van Der Kooy D, Rossant J, Reith A, Bernstein A (1991): Contiguous patterns of c-kit and stem expression: analysis of mutations at the W&SL loci. Development 113:1207-1221.
30. Nishikawa S, Kusakabe M, Yoshinaga K, Ogawa M, Hayashi SI, Kunisada Era T, Sakakura T, Nishikawa SI (1991): In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: Two distinct waves of c-kit-dependency during melanocyte development. EMBO J 10:2111-2118.
31. Nocka K, Majumder S, Chabot B, Ray P, Cervone M, Bernstein A, Besmer P (1989): Expression of c-kit gene products in cellular targets of W mutations in normal and W mutant mice-evidence for an impaired c-kit kinase in mutant mice. Genes Dev 3:816-826.
32. Packer AI, Hsu YC, Besmer P, Bachvarova RF (1994): The ligand of the c-kit receptor promotes oocytes growth. Dev Biol 161:194-205.
33. Packer AI, Besmer P, Bachvarova RF (1995): Kit ligand mediates survival of type A spermatogonia and dividing spermatocytes in postnatal mouse testes. Mol Reprod Dev 42:303-310.
34. Pawson T (1991): Signal transduction in the control of cell growth and development. Trends Genet 7:343-345.
35. Qiu F, Ray P, Brown K, Barker PE, Jhanwar S, Ruddle FH, Besmer P (1988): Primary structure of c-kit: Relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 7:1003-1011.
36. Rossi P, Albanesi C, Grimaldi P, Geremia R (1991): Expression of the mRNA for the ligand of c-kit in mouse sertoli cells. Biochem Biophys Res Commun 176:910-914.
37. Rossi P, Marziali G, Albanesi C, Charlesworth A, Geremia R, Sorrentina V (1992): A novel c-kit transcript, potentially encoding a truncated receptor, originates within a kit gene intron in mouse spermatids. Dev Biol 152:203-207.
38. Rossi P, Dolci S, Albanesi C, Grimaldi P, Ricca R, Geremia R (1993): Follicle-stimulating hormone induction of steel factor (SLF) mRNA in mouse Sertoli cells and stimulation of DNA synthesis in spermatogonia by soluble SLF. Dev Biol 155:68-74.
39. Rottapel R, Reedijk M, Williams DE, Lyman SD, Anderson DM, Pawson T, Bernstein A (1991): The steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the steel factor. Mol Cell Biol 11:3043-3051.
40. Russell ES (1979): Heredity anemias of the mouse: A review for geneticists. Adv Genet 20:357-459.
41. Sabeur K, Edwards DP, Meizel S (1996): Human sperm plasma membrane progesterone receptor(s) and the acrosome reaction. Biol Reprod 54:993-1001.
42. Saling PM (1986): Mouse sperm antigens that participate in fertilization: A monoclonal antibody prevents zona penetration by inhibition of the acrosome reaction. Dev Biol 117:511-519.
43. Saling PM (1989): Mammalian sperm interaction with extracellular matrices of the egg. Oxf Rev Reprod Biol 11:339-388.
44. Sandlow JI, Cohen MB, Sandra A (1994): Expression of the c-kit ligand in a murine model of human subfertile conditions. In "Program of the 68th Annual Meeting of the North Central Section of the American Urological Association." Boca Raton, FL: CRC Press, abstract 200.
45. Sandlow JI, Feng HL, Sandra A (1996a): Expression of c-kit and its ligand, stem cell factor, in normal and subfertile human testicular tissue. J Androl 17:403-408.
46. Sandlow JI, Feng HL, Sandra A (1996b): Expression of the c-kit receptor in spermatogenic cells and normal sperm. J Androl 17(supp):24 (abstract 6).
47. Sandlow JI, Feng HL, Sandra A (1997): Localization and expression of the c-kit receptor protein in human and rodent testis and sperm. Urology 49:494-500.
48. Serve H, Hsu YC, Besmer P (1994): Tyrosine residue 719 of the c-kit receptor is essential for binding of the p85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells. J Biol Chem 269:6026-6030.
49. Sorrentino V, Giorgi M, Geremia R, Besmer P, Rossi P (1991): Expression of the c-kit proto-oncogene in the murine male germ cells. Oncogene 6:149-151.
50. d mutant mice. Development 113:1031-1035.
51. 42 spotting phenotype results from a missense mutation in the c-kit receptor kinase. Science 247:209-212.
52. Ullrich A, Schlessinger J (1990): Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
53. Walensky LD, Snyder SH (1995): Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosome of mammalian sperm. J Cell Biol 130:857-869.
54. Wassarman PM (1990): Regulation of mammalian fertilization by zona pellucida glycoproteins. J Reprod Fertil 42:79-87.
55. Yanagimachi R (1994): Mammalian fertilization. In: E Knobil, JD Niell, LL Ewing, GS Greenwald, CL Markert, DW Pfaff (eds): "The Physiology of Reproduction," Vol 1. New York: Raven Press, pp 189-319.
56. Yarden Y, Kuang WJ, Yang FT, Coussens L, Munemitsu S, Dull TJ, Chen E, Schlessinger J, Francke U, Ullrich A (1987): Human proto-oncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J 6:3341-3351.
57. Yarden Y, Ullrich A (1988): Growth factor receptor tyrosine kinase. Annu Rev Biochem 57:443-478.
58. Yoshinaga K, Nishikawa S, Ogawa M, Hayashi SI, Kunisada T, Fujomoto T, Nishikawa SI (1991): Role of c-kit in mouse spermatogenesis: Identification of spermatogonia as a specific site of c-kit expression and function. Development 113:689-699.
59. Zhang Z, Anthony RV (1994): Porcine stem cell factor/c-kit ligand: Its molecular cloning and localization within the uterus. Biol Reprod 50:95-102.