Mycophenolate mofetil pharmacokinetics in renal transplant recipients on peritoneal dialysis

Transplant International

Volumn 11, Issue 1, 1998, Pages 53-57

  Morgera, Stanislao ^a   Budde, Klemens ^a   Lampe, Dagmar ^b   Ahnert, Volker ^a   Fritsche, Lutz ^a   Kuchinke, Simone ^a   Neumayer, Hans H ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Inst Clin Pharmacol and Toxicol   (Germany)

Author keywords

Kidney transplantation, mycophenolate mofetil; Mycophenolate mofetil, kidney transplantation; Peritoneal dialysis, mycophenolate mofetil

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; MALE; PERITONEAL DIALYSIS; PRIORITY JOURNAL;

ADULT; AREA UNDER CURVE; FEMALE; GLOMERULAR FILTRATION RATE; GLUCURONATES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; PERITONEAL DIALYSIS; PROSPECTIVE STUDIES;

EID: 0031937989     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001470050102     Document Type: Article

References (12)

1. Allison AC, Eugui EM (1993) Mycophenolate mofetil, a rationally designed immunosuppressive drug. Clin Transplant 7: 96-112
2. Bullingham R, Monroe S, Nicholls A, Hale M (1996) Pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after single-dose oral and intravenous administration. J Clin Pharmacol 36: 315-324
3. Cockroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16: 31
4. European Mycophenolate Mofetil Cooperative Study Group (1995) Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection. Lancet 345: 1321-1325
5. Franklin TJ, Cook JM (1969) The inhibition of nucleic acidsynthesis by mycophenolic acid. Biochem J 113: 515-524
6. Fulton B, Markham A (1996) Mycophenolate mofetil: a review of its pharmacodynamic and pharmacokinetic properties and clinical efficiacy in renal transplantation. Drugs 51: 278-298
7. Lee WA, Gu L, Miksztal AR, Chu N, Leung K, Nelson PH (1990) Bioavailability improvement of mycophenolic acid through amino ester derivatization. Pharm Res 7: 161-166
8. Nowak I, Shaw LM (1995) Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics. Clin Chem 41: 1011-1017
9. Salaman JR, Griffin PJA, Johnson RW, Kohlhaw K, Land W, Moore R, Pichlmayr R, Sells R (1993) Controlled trial of RS-61443 in renal transplant patients recieving cyclosporine monotherapy. Transplant Proc. 25: 695-696
10. Sollinger HW, Deierhoi MH, Belzer FO, Diethelm AG, Kauffman RS (1992) RS-61443 - a phase I clinical trial and pilot rescue study. Transplantation 53: 428-432
11. Twardowski ZJ, Nolph KD, Khanna R, Prowant BF, Ryan LP, Moore HL, Nielsen MP (1987) Pertitoneal equilibration test. Perit Dial Bull 7: 138-147
12. Young CJ, Sollinger HW (1994) RS-61443:A new immunosuppressive agent. Transplant Proc 26: 1264-1276