New clonal karyotypic abnormalities acquired following autologous bone marrow transplantation for acute myeloid leukemia do not appear to confer an adverse prognosis

Bone Marrow Transplantation

Volumn 21, Issue 4, 1998, Pages 395-399

  Imrie, K R ^a,b   Dube I ^a   Prince, H M ^a   Girouard, C ^a   Crump, M ^a   Keating, A ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

Author keywords

Acute myeloid leukemia; Bone marrow transplantation; Cytogenetics; Myelodysplasia

Indexed keywords

ETOPOSIDE; MELPHALAN;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW PURGING; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL FEATURE; FEMALE; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASIA; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; WHOLE BODY RADIATION;

EID: 0031937963     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701105     Document Type: Article

References (19)

1. Larson RA, LeBeau MM, Vardiman JW. The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: a 12 year study (1970-1982). Cancer Genet Cytogenet 1983; 10: 219-236.
2. Arthur DC, Berger R, Golcomb HM. The clinical significance of karyotype in acute myeloid leukemia. Cancer Genet Cytogenet 1989; 40: 203-216.
3. Perot C, Van der Akker J, Laporte JP et al. Multiple chromosomal abnormalities in patients with acute leukemia after autologous bone marrow transplantation using total body irradiation and marrow purged with mafosfamide. Leukemia 1993; 7: 509-515.
4. Swansbury GJ, Lawler SD, Alimena G et al. Long-term survival in acute myelogenous leukemia: a second follow-up of the fourth international workshop on chromosomes in leukemia. Cancer Genet Cytogenet 1994; 73: 1-7.
5. Rowley JD, LeBeau MM. Cytogenetic and molecular analysis of therapy-related leukemias. Ann New York Acad Sci 1989; 567: 130-140.
6. Yunis JJ, Brunning RD. Prognostic significance of chromosomal abnormalities in acute leukemias and myelodysplastic syndromes. Clin Haematol 1986; 15: 597-604.
7. Levine EG, Bloomfield CD. Secondary myelodysplastic syndromes and leukemias. Clin Haematol 1986; 15: 1037-1042.
8. Rohatiner A. Myelodysplasia and acute myeloid leukemia after myeloablative therapy with autologous stem-cell transplantation. J Clin Oncol 1994; 12: 2521-2523.
9. Mitelman F (ed). Guidelines for Cancer Cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature. Karger: Basel, 1991.
10. Traweek ST, Slovak ML, Nademanee AP et al. Clonal karyotypic hematopoietic cell abnormalities occurring after autologous bone marrow transplantation for Hodgkin's disease with non-Hodgkin's lymphoma. Blood 1994; 84: 957-963.
11. LeBeau MM, Albain KS, Larson RA. Clinical and Cytogenetic correlation's in 63 patients with therapy-related myelodysplastic syndrome and acute myeloid leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7. J Clin Oncol 1986; 4: 325-345.
12. Miller JS, Arthur DC, Litz CE et al. Myelodysplastic syndrome after autologous bone marrow transplantation: an additional late complication of curative cancer therapy. Blood 1994; 83: 3780-3786.
13. Darrington DL, Vose JM, Anderson JR et al. Incidence and characterization of secondary myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemoradiotherapy and autologous stem-cell transplantation for lymphoid malignancies. J Clin Oncol 1994; 12: 2527-2534.
14. Stone RM, Neuberg D, Soiffer R et al. Myelodysplastic syndrome as a late complication of autologous bone marrow transplantation for non-Hodgkin's lymphoma. J Clin Oncol 1994, 12: 2535-2542.
15. Pederson-Bjergaard J, Phillip P, Larsen SO et al. Therapy related myelodysplasia and acute myeloid leukemia. Cytogenetic characteristics of 115 cases and risk in seven cohorts of patients treated intensively for malignant disease in the Copenhagen series. Leukemia 1993; 7: 1975-1986.
16. Baker MC, Lawler SD, Harris H et al. Radiation damage in patients treated by total body irradiation, bone marrow grafting, and cyclosporin. Radiat Res 1986; 105: 413-424.
17. Mastrianni DM, Tung NM, Tenen DG. Acute myeloid leukemia: current treatment and future direction. Am J Med 1992; 92: 286-295.
18. Lawler SD, Harris H, Millar J et al. Cytogenetic follow-up studies of recipients of T cell depleted allogeneic bone marrow. Br J Haematol 1986; 65: 143-150.
19. Van der Berg H, Beverstock JP, Westerhof JP, Vossen JM, Chromosomal studies after bone marrow transplantation for leukemia in children. Bone Marrow Transplant 1991; 7: 335-342.