Plasticity in adult and ageing sympathetic neurons

Progress in Neurobiology

Volumn 54, Issue 3, 1998, Pages 249-288

  Cowen, Timothy ^a   Gavazzi, Isabella ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTRANSMITTER; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; TYROSINE KINASE RECEPTOR;

ADULT; AGED; CELL AGING; CELL SURVIVAL; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NERVE FIBER TRANSPORT; NERVE SPROUTING; NEUROTRANSMISSION; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYMPATHETIC NERVE CELL;

EID: 0031937841     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-0082(97)00071-3     Document Type: Article

References (390)

1. Abdel-Rahman T. A., Collins K. J., Cowen T., Rustin M. Immunohistochemical, morphological and functional changes in the peripheral sudomotor neuro-effector system in elderly people. J. Auton. Nerv. Syst. 37:1992;187-198.
2. Abdel-Rahman T. A., Cowen T. Neurodegeneration in sweat glands and skin of aged rats. J. Auton. Nerv. Syst. 46:1993;55-63.
3. Abercrombie M. Estimation of nuclear population from microtome sections. Anat. Rec. 94:1946;239-247.
4. Aberdeen J., Milner P., Lincoln J., Burnstock G. Guanethidine sympathectomy of mature rats leads to increases in calcitonin gene-related peptide and vasoactive intestinal polypeptide-containing nerves. Neuroscience. 47:1992;453-461.
5. Abrahamson I. K., Wilson P. A., Rush R. A. Production and transport of endogenous trophic activity in a peripheral nerve following target removal. Brain Res. 392:1986;117-126.
6. Adler J. E., Black I. B. Plasticity of substance P in mature and aged sympathetic neurons in culture. Science. 225:1984;1499-1500.
7. Airaksinen M. S., Koltzenburg M., Lewin G., Masu Y., Helbig C., Wolf E., Brem G., Toyka K. V., Thoenen H., Meyer M. Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation. Neuron. 16:1996;287-295.
8. Albers K. M., Wright D. E., Davis B. M. Overexpression of nerve growth factor in epidermis of transgenic mice causes hypertrophy of the peripheral nervous system. J. Neurosci. 14:1994;1422-1432.
9. Anderson D. J. Cell fate determination in the peripheral nervous system: the sympathoadrenal progenitor. [Review]. J. Neurobiol. 24:1993;185-198.
10. Andrews T. J., Cowen T. In vivo infusion of NGF induces the organotypic regrowth of perivascular nerves following their atrophy in aged rats. J. Neurosci. 14:1994;3048-3058.
11. Andrews T. J., Cowen T. Nerve growth factor enhances the dendritic arborization of sympathetic ganglion cells undergoing atrophy in aged rats. J. Neurocytol. 23:1994;234-241.
12. Andrews T. J., Li D., Halliwell J., Cowen T. The effect of age on dendrites in the rat superior cervical ganglion. J. Anat. 184:1994;111-117.
13. Andrews T., Lincoln J., Milner P., Burnstock G., Cowen T. Differential regulation of tyrosine hydroxylase protein and activity in rabbit sympathetic neurones following long-term cold exposure: altered responses in ageing. Brain Res. 624:1993;69-74.
14. Andrews T. J., Thrasivoulou C., Nesbit W., Cowen T. Target-specific differences in the dendritic morphology and neuropeptide content of neurons in the rat SCG during development and aging. J. Comp. Neurol. 368:1996;33-44.
15. Angeletti P. U., Levi-Montalcini R., Caramia F. Analysis of the effects of the antiserum to the nerve growth factor in adult mice. Brain Res. 27:1971;343-355.
16. Anton E. S., Weskamp G., Reichardt L. F., Matthew W. D. Nerve growth factor and its low-affinity receptor promote schwann cell migration. Proc. Natl. Acad. Sci. USA. 91:1994;2795-2799.
17. Ayer-Lelievre C. S., Ebendal T., Olson L., Seiger A. Localization of nerve growth factor-like immunoreactivity in rat nervous tissue. Med. Biol. 61:1983;296-304.
18. Baker D. M., Santer R. M. Morphometric studies on pre- and paravertebral sympathetic neurons in the rat: changes with age. Mech. Ageing Dev. 42:1988;139-145.
19. Baker D. M., Santer R. M. A quantitative study of the effects of age on the noradrenergic innervation of Auerbach's plexus in the rat. Mech. Age. Dev. 42:1988;147-158.
20. Balicegordon R. J., Lichtman J. W. In vivo observations of presynaptic and postsynaptic changes during the transition from multiple to single innervation at developing neuromuscular junctions. J. Neurosci. 13:1993;834-855.
21. Barbacid M. Nerve growth factor - a tale of 2 receptors. Oncogene. 8:1993;2033-2042.
22. Beg A. A., Baltimore D. An essential role for NF-kB in preventing TNF-a-induced cell death. Science. 274:1996;782-784.
23. Berzaghi M. D., Cooper J., Castren E., Zafra F., Sofroniew M., Thoenen H., Lindholm D. Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) messenger RNA levels in the developing rat hippocampus. J. Neurosci. 13:1993;3818-3826.
24. Bevan R. D., Tsuru H. Functional and structural changes in the rabbit ear artery after sympathetic denervation. Circ. Res. 49:1981;478-485.
25. Biguet N. F., Rittenhouse A. R., Mallet J., Zigmond R. E. Preganglionic nerve stimulation increases mRNA levels for tyrosine hydroxylase in the rat superior cervical ganglion. Neurosci. Lett. 104:1989;189-194.
26. Birren S. J., Lo L. C., Anderson D. J. Sympathetic neuroblasts undergo a developmental switch in trophic dependence. Development. 119:1993;597-610.
27. Bjerre B., Wiklund L., Edwards D. C. A study of the de- and regenerative changes in the sympathetic nervous system of the adult mouse after treatment with the antiserum to nerve growth factor. Brain Res. 92:1975;257-278.
28. Bjorklund H., Hokfelt T., Goldstein M., Terenius L., Olson L. Appearance of the noradrenergic markers tyrosine hydroxylase and neuropeptide Y in cholinergic nerves of the iris following sympathectomy. J. Neurosci. 5:1985;1633-1643.
29. Black I. B., Adler J. E., Dreyfus C. F., Jonakait G. M., Katz D. M., LaGamma E. F., Markey K. M. Neurotransmitter plasticity at the molecular level. Science. 225:1984;1266-1270.
30. Blottner D., Baumgarten H. G. Basic fibroblast growth factor prevents neuronal death and atrophy of retrogradely labeled preganglionic neurons in vivo. Exp. Neurol. 118:1992;35-46.
31. Borasio G. D., Markus A., Wittinghofer A., Barde Y. A., Heumann R. Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons. J. Cell Biol. 121:1993;665-672.
32. Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu. Rev. Neurosci. 18:1995;223-255.
33. Branco D., Albino-Teixeira A., Azevedo I., Osswald W. Structural and functional alterations caused at the extranueronal level by sympathetic denervation of blood vessels. Naunyn-Schmiedeberg's Arch. Pharmacol. 326:1984;302-312.
34. Brauer M. M., Lincoln J., Blundell D., Corbacho A. Postnatal development of noradrenaline-containing nerves of the rat uterus. J. Auton. Nerv. Syst. 39:1992;37-49.
35. Brauer M. M., Lincoln J., Milner P., Sarner S., Blundell D., Passaro M., Corbacho A., Burnstock G. Plasticity of autonomic nerves: differential effects of long-term guanethidine sympathectomy on the sensory innervation of the rat uterus during maturation. Int. J. Devl. Neurosci. 12:1994;579-586.
36. Brauer M. M., Lincoln J., Sarner S., Blundell D., Milner P., Passaro M., Burnstock G. Maturational changes in sympathetic and sensory innervation of the rat uterus: effects of neonatal capsaicin treatment. Int. J. Dev. Neurosci. 12:1994;157-171.
37. Brownlee M. Advanced protein glycosylation in diabetes and aging. [Review]. Annual Review of Medicine. 46:1995;223-234.
38. Buettner H. M., Pittman R. N. Quantitative effects of laminin concentration on neurite outgrowth in vitro. Dev. Biol. 145:1991;266-276.
39. Buj-Bello A., Buchman V. L., Horton A., Rosenthal A., Davies A. M. GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron. 15:1995;821-828.
40. Buj-Bello A., Pinon L. G. P., Davies A. M. The survival of NGF-dependent but not BDNF-dependent cranial sensory neurons is promoted by several different neurotrophins early in their development. Development. 120:1994;1573-1580.
41. Bunge M. B., Bunge R. P., Kleitman N., Dean A. C. Role of peripheral nerve extracellular matrix in Schwann cell function and in neurite regeneration. [Review]. Dev. Neurosci. 11:1989;348-360.
42. Burnstock, G. (1974) Degeneration and orientated growth of autonomic nerve in relation to smooth muscle in joint tissue cultures and anterior eye chamber transplants. In: Dynamics of Degeneration and Growth In Neurons, pp. 509-519. Eds K. Fuxe, L. Olson and Y. Zotterman. Pergamon: Oxford.
43. Canossa M., Twiss J. L., Verity A. N., Shooter E. M. p75(NGFR) and TrkA receptors collaborate to rapidly activate a p75(NGFR)-associated protein kinase. EMBO J. 15:1996;3369-3376.
44. Carlson S. L., Albers K. M., Beiting D. J., Parish M., Conner J. M., Davis B. M. NGF modulates sympathetic innervation of lymphoid tissues. J. Neurosci. 15:1995;5892-5899.
45. Carter B. D., Kaltschmidt C., Kaltschmidt B., Offenhauser N., Bohm-Matthaei R., Baeuerle P. A., Barde Y.-A. Selective activation of NF-kB by nerve growth factor through the neurotrophic receptor p75. Science. 272:1996;542-545.
46. Carter B. D., Lewin G. R. Neurotrophins live or let die: does p75NTR decide? [Review]. Neuron. 18:1997;187-190.
47. Chaldakov G. N., Andrews T. J., Burnstock G., Cowen T. An ultrastructural study of ageing in cerebral blood vessels of the rat: accumulations of neurofilaments and muscle basal lamina in old age. Neurosci. Lett. 42(Suppl.):1992;S28.
48. Chamley J. H., Campbell G. R., Burnstock G. An analysis of the interactions between sympathetic nerve fibers and smooth muscle cells in tissue culture. Dev. Biol. 33:1973;344-361.
49. Chamley J. H., Campbell G. R., Burnstock G. Dedifferentiation, redifferentiation and bundel formation of smooth msucle cells in tissue culture: the influence of cell number and nerve fibres. J. Embryol. exp. Morph. 32:1974;297-323.
50. Changeux, J.-P. (1985) Neuronal Man, The Biology of Mind. Oxford University Press: Oxford.
51. Chao M. V., Hempstead B. L. p75 and Trk: a two-receptor system. [Review]. Trends Neurosci. 18:1995;321-326.
52. Cho S., Son J. H., Park D. H., Aoki C., Song X., Smith G. P., Joh T. H. Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice. Proc. Natl. Acad. Sci. USA. 93:1996;2862-2866.
53. Clegg D. O., Large T. H., Bodary S. C., Reichardt L. F. Regulation of nerve growth factor mRNA levels in developing rat heart ventricle is not altered by sympathectomy. Dev. Biol. 134:1989;30-37.
54. Cole D. F., Bloom S. R., Burnstock G., Butler J. M., McGregor G. P., Saffrey M. J., Unger W. G., Zhang S. Q. Increase in SP-like immunoreactivity in nerve fibers of rabbit iris and ciliary body one to four months following sympathetic denervation. Exp. Eye Res. 37:1983;191-197.
55. Collins K. J. The autonomic nervous system in old age. Rev. Clin. Gerontol. 1:1991;337-345.
56. Collins, K. J. and Cowen, T. (1997) Disorders of the autonomic nervous system. In: Textbook of Geriatric Medicine and Gerontology. Eds J. C. Brocklehurst, R. C. Tallis and H. M. Fillitt. pp. 539-564. Livingstone: New York (in press).
57. Cooper J. D., Lindholm D., Sofroniew M. V. Reduced transport of [125I]nerve growth factor by cholinergic neurons and down-regulated TrkA expression in the medial septum of aged rats. Neuroscience. 62:1994;625-629.
58. Corbacho, A., Brauer, M. M. and Perez, T. (1997) Development and maturation and noradrenaline-containing nerves of the rat uterine artery. Effects of acute and chronic oestrogen treatment. Int. J. Dev. Neurosci, 15, 363-371.
59. Cordon-Cardo C., Tapley P., Jing S. Q., Nanduri V., O'Rourke E., Lamballe F., Kovary K., Klein R., Jones K. R., Reichardt L. F.et al. The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell. 66:1991;173-183.
60. Cowen T. Ageing in the autonomic nervous system: a result of nerve-target interactions? A review. Mech. Age. Dev. 68:1993;163-173.
61. Cowen T., Haven A. J., Milner P., Lincoln J., Burnstock G. Increase in neuropeptide Y, but not noradrenaline, in the superior cervical ganlion of rabbits chronically exposed to cold. J. Auton. Nerv. Syst. 24:1988;175-178.
62. Cowen T., Haven A. J., Wen Qin C., Gallen D. D., Franc F., Burnstock G. Development and ageing of perivascular adrenergic nerves in the rabbit. A quantitative fluorescence histochemical study using image analysis. J. Auton. Nerv. Syst. 5:1982;317-336.
63. Cowen T., Gavazzi I., Weingartner J., Crutcher K. A. Levels of NGF protein do not correlate with changes in innervation of the rat iris in old age. Neuroreport. 7:1996;2216-2220.
64. Cowen T., Jenner C., Xiao Song Gu, Budi Santoso A. W., Gavazzi I. Responses of mature and aged sympathetic neurons to laminin and NGF: an in vitro study. Neurochem. Res. 22:1997;1003-1011.
65. Cowen T., Thrasivoulou C., Shaw S. A., Abdel-Rahman T. A. Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves. J. Auton. Nerv. Syst. 60:1996;215-224.
66. Creedon D., Tuttle J. B. Nerve growth factor synthesis in vascular smooth muscle. Hypertension. 18:1991;730-741.
67. Crowley C., Spencer S. D., Nishimura M. C., Chen K. S., Pittsmeek S., Armanini M. P., Ling L. H., Mcmahon S. B., Shelton D. L., Levinson A. D., Phillips H. S. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell. 76:1994;1001-1011.
68. Crutcher K. A., Brothers L., Davis J. N. Sprouting of sympathetic nerves in the absence of afferent input. Exp Neurol. 66:1979;778-783.
69. Crutcher K. A. Age-related decrease in sympathetic sprouting is primarily due to decreased target receptivity: implications for understanding brain function. Neurobiol. Aging. 11:1990;175-183.
70. Crutcher, K. A., Weingartner, J. A., Gavazzi, I. and Cowen, T. (1996) NGF in the rat external carotid artery is primarily associated with nerve fibres and shows age-related declines. Soc. Neurosci. Abstr. 22, 1236.
71. Crutcher K. A., Saffran B. N. Developmental remodeling of neuronal projections: evidence for trophomorphism? Comm. Dev. Neurobiol. 1:1991;119-141.
72. Crutcher K. A., Weingartner J. Hippocampal NGF levels are not reduced in the aged Fischer-344 Rat. Neurobiol. Aging. 12:1991;449-454.
73. Curtis R., Adryan K. M., Stark J. L., Park J. S., Compton D. L., Weskamp G., Huber L. J., Chao M. V., Jaenisch R., Lee K. F.et al. Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron. 14:1995;1201-1211.
74. Danielsen N., Pettmann B., Vahlsing H. L., Manthorpe M., Varon S. Fibroblast growth factor effects on peripheral nerve regeneration in a silicone chamber model. J. Neurosci. Res. 20:1988;320-330.
75. Davies A. M. Neurotrophic factors - switching neurotrophin dependence. Curr. Biol. 4:1994;273-276.
76. Davies A. M. The neurotrophic hypothesis: where does it stand? Philos. Trans. R. Soc. Lond. [B]. 351:1996;389-394.
77. Davies A. M. Neurotrophin switching: where does it stand? Current Opinion in Neurobiol. 7:1997;110-118.
78. Davies A. M., Lee K. F., Jaenisch R. p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron. 11:1993;565-574.
79. Davies A. M., Minichiello L., Klein R. Developmental changes in NT3 signalling via TrkA and TrkB in embryonic neurons. EMBO J. 14:1995;4482-4489.
80. Davis B. M., Albers K. M., Seroogy K. B., Katz D. M. Overexpression of nerve growth factor in transgenic mice induces novel sympathetic projections to primary sensory neurons. J. Comp. Neurol. 349:1994;464-474.
81. de Curtis I. Neuronal interactions with the extracellular matrix. Current Opinion in Cell Biol. 3:1991;824-831.
82. de Pablo F., de la Rosa E. J. The developing CNS: a scenario for the action of proinsulin, insulin and insulin-like growth factors. [Review]. Trends in Neurosci. 18:1995;143-150.
83. D'Ercole A. J., Ping Ye., Calikoglu A. S., Gutierrez-Ospina G. The role of the insulin-like growth factors in the central nervous system. Mol. Neurobiol. 13:1996;227-255.
84. Dering M. A., Santer R. M., Watson A. H. Age-related changes in the morphology of preganglionic neurons projecting to the rat hypogastric ganglion. J. Neurocytol. 25:1996;555-563.
85. Dhall U., Cowen T., Haven A. J., Burnstock G. Perivascular noradrenergic and peptide-containing nerves show different patterns of change during development and ageing in the guinea-pig. J. Auton. Nerv. Syst. 16:1986;109-126.
86. Diamond J., Foerster A., Holmes M., Coughlin M. Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF. J. Neurosci. 12:1992;1467-1476.
87. Diamond, J., Gloster, A. and Kitchener, P. (1992b) Regulation of the sensory innervation of skin: trophic control of collateral sprouting. In: Sensory Neurons: Diversity, Development and Plasticity, pp. 309-332. Ed. S. Scott. O.U.P.: Oxford.
88. Diamond J., Holmes M., Coughlin M. Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat. J. Neurosci. 12:1992;1454-1466.
89. Dimitriadou V., Aubineau P., Taxi J., Seylaz J. Ultrastructural changes in the cerebral artery wall induced by long-term sympathetic denervation. Blood Vessels. 25:1988;122-143.
90. Distefano P. S., Friedman B., Radziejewski C., Alexander C., Boland P., Schick C. M., Lindsay R. M., Wiegand S. J. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron. 8:1992;983-993.
91. Donohue S. J., Head R. J., Stitzel R. E. Elevated nerve growth factor levels in young spontaneously hypertensive rats. Hypertension. 14:1989;421.
92. Doyu M., Sobue G., Ken E., Kimata K., Shinomura T., Yamada Y., Mitsuma T., Takahashi A. Laminin-a, laminin-b1, and laminin-b2 chain gene expression in transected and regenerating nerves - regulation by axonal signals. J. Neurochem. 60:1993;543-551.
93. Durbec P., Marcos-Gutierrez C. V., Kilkenny C., Grigoriou M., Wartiowaara K., Suvanto P., Smith D., Ponder B., Costantini F., Saarma M., Sariola H., Pachnis V. GDNF signalling through the Ret receptor tyrosine kinase. Nature. 381:1996;789-793.
94. Ebendal T., Olson L., Seiger A. The level of nerve growth factor (NGF) as a function of innervation. Exp. Cell Res. 148:1983;311-317.
95. Ebendal T., Olson L., Seiger A., Hedlund K.-O. Nerve growth factors in the rat iris. Nature. 286:1980;25-28.
96. Edelman G. M. Modulation of cell adhesion during induction, histogenesis, and perinatal development of the nervous system. Ann. Rev. Neurosci. 7:1984;339-377.
97. Edgar D. Neuronal laminin receptors. Trends Neurosci. 12:1989;248-251.
98. Edgar D. The expression and interactions of laminin in the developing nervous system. Cell Differentiation Develop. 32:1990;377-382.
99. Edgar D., Timpl R., Thoenen H. Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies. J. Cell Biol. 1069:1988;1299-1306.
100. Edwards R. H., Rutter W. J., Hanahan D. Directed expression of NGF to pancreatic beta cells in transgenic mice leads to selective hyperinnervation of the islets. Cell. 58:1989;161-170.
101. Edwards S. N., Tolkovsky A. M. Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal. J. Cell Biol. 124:1994;537-546.
102. Ehrhard P. B., Otten U. Postnatal ontogeny of the neurotrophin receptors trk and trkb mRNA in rat sensory and sympathetic ganglia. Neurosci. Lett. 166:1994;207-210.
103. Eide F. F., Lowenstein D. H., Reichardt L. F. Neurotrophins and their receptors - current concepts and implications for neurologic disease. [Review]. Exp. Neurol. 121:1993;200-214.
104. Eleftheriou C. S., Trakas N. B., Tzartos S. J. Cellular ageing related proteins secreted by human fibroblasts. [Review]. Mutation Res. 256:1991;127-138.
105. Elkabes S., Dreyfus C. F., Schaar D. G., Black I. B. Embryonic sensory development - local expression of neurotrophin-3 and target expression of nerve growth factor. J. Comp. Neurol. 341:1994;204-213.
106. Elshamy W. M., Linnarsson S., Lee K. F., Jaenisch R., Ernfors P. Prenatal and postnatal requirements of NT-3 for sympathetic neuroblast survival and innervation of specific targets. Development. 122:1996;491-500.
107. Engvall E. Laminin variants - why, where and when. Kidney. Int. 43:1993;2-6.
108. Engvall E. Structure and function of basement membranes. [Review]. Int. J. Devl. Biol. 39:1995;781-787.
109. Engvall E., Earwicker D., Haaparanta T., Ruoslahti E., Sanes J. R. Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits. Cell Regul. 1:1990;731-740.
110. Ernfors P., Lee K. F., Jaenisch R. Target derived and putative local actions of neurotrophins in the peripheral nervous system. [Review]. Progress Brain Res. 103:1994;43-54.
111. Ernfors P., Merlio J. P., Lindvall O. Cells expressing messenger-RNA for neurotrophins and their receptors during embryonic rat development. Eur. J. Neurosci. 4:1992;1140-1158.
112. Falckh P. H., Harkin L. A., Head R. J. Nerve growth factor messenger RNA content parallels altered sympathetic innervation in the spontaneously hypertensive rat. Clin. Exp Pharmacol. Physiol. 19:1992;541-545.
113. Falckh P. H., Harkin L. A., Head R. J. Resistance vessel gene expression of nerve growth factor is elevated in young spontaneously hypertensive rats. J. Hypertension. 10:1992;913-918.
114. Fan Q., Smith P. G. Decreased vasoactive intestinal polypeptide-immunoreactivity of parasympathetic neurons and target innervation following long-term sympathectomy. Reg. Pep. 48:1993;337-343.
115. Farinas I., Jones K. R., Backus C., Wang X. Y., Reichardt L. F. Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature. 369:1994;658-661.
116. Farinas I., Yoshida C. K., Backus C., Reichardt L. F. Lack of neurotrophin-3 results in death of spinal senory neurons and premature differentiation of their precursors. Neuron. 17:1996;1065-1078.
117. Federoff H. J., Lawrence D., Brownlee M. Nonenzymatic glycosylation of laminin and the laminin peptide CIKVAVS inhibits neurite outgrowth. Diabetes. 42:1993;509-513.
118. Feher E., Penzes L. Density of substance P, vasoactive intestinal polypeptide and somatostatin-containing nerve fibers in the ageing small intestine of the rats. Gerontology. 33:1987;341-348.
119. Fike E. A., Simons E., Boswell C., Smith P. G. Sensory nerves impair sympathetic reinnervation and recovery of smooth muscle function. Exp. Neurol. 118:1992;85-94.
120. Filogamo G., Marchisio P. C. Choline acetyltransferase activity of rabbit ileum wall. The effects of extrinsic and intrinsic denervation and of combined experimental hypertrophy. Arch. Int. Physiol. Biochimie. 78:1970;141-152.
121. Flaumenhaft R., Rifkin D. B. Extracellular matrix regulation of growth factor and protease activity. Current Opinion in Cell Biol. 3:1991;817-823.
122. Forehand C. J. Density of somatic innervation on mammalian autonomic ganglion cells is inversely related to dendritic complexity and preganglionic convergence. J. Neurosci. 5:1985;3403-3408.
123. Frade J. M., Rodriguez-Tebar A., Barde Y.-A. Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature. 383:1996;166-168.
124. Friedman W. F., Pool P. E., Jacobowitz D., Seagren S. C., Braunwald E. Sympathetic innervation of the developing rabbit heart. Circ. Res. 23:1968;25-31.
125. Fronek K., Bloor C. M., Amiel D., Chvapil M. Effect of long-term sympathectomy on the arterial wall in rabbits and rats. Exp. Mol. Path. 28:1978;279-289.
126. Gabella G. Size of neurons and glial cells in the intramural ganglia of the hypertrophic intestine of the guinea-pig. J. Neurocytol. 13:1984;73-84.
127. Gabella G. Hypertrophic smooth muscle. V. Collagen and other extracellular materials. Vascularization. Cell Tiss. Res. 235:1984;275-283.
128. Gabella G. Fall in the number of myenteric neurons in aging guinea pigs. Gastroenterology. 96:1989;1487-1493.
129. Gabella G. Hypertrophy of visceral smooth muscle. [Review]. Anat. Embryol. 182:1990;409-424.
130. Gabella G., Berggren T., Uvelius B. Hypertrophy and reversal of hypertrophy in rat pelvic ganglion neurons. J. Neurocytol. 21:1992;649-662.
131. Gabella G., Uvelius B. Urinary bladder of rat: fine structure of normal and hypertrophic musculature. Cell Tiss. Res. 262:1990;67-79.
132. Gabella G., Uvelius B. Effect of decentralization or contralateral ganglionectomy on obstruction-induced hypertrophy of rat urinary bladder muscle and pelvic ganglion [published erratum appears in J. Neurocytol. 22, 1113]. J. Neurocytol. 22:1993;827-834.
133. Gabella G., Uvelius B. Reversal of muscle hypertrophy in the rat urinary bladder after removal of urethral obstruction. Cell Tiss. Res. 277:1994;333-339.
134. Garcia I., Martinou I., Tsujimoto Y., Martinou J. C. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science. 258:1992;302-304.
135. Gavazzi I. Collateral sprouting and responsiveness to nerve growth factor of ageing neurons. Neurosci. Lett. 189:1995;47-50.
136. Gavazzi I., Andrews T. J., Thrasivoulou C., Cowen T. Influence of target tissues on their innervation in old age: a transplantation study. NeuroReport. 3:1992;717-720.
137. Gavazzi I., Boyle K. S., Cowen T. Extracellular matrix molecules influence innervation density in rat cerebral blood vessels. Brain Res. 734:1996;167-174.
138. Gavazzi I., Boyle K. S., Edgar D., Cowen T. Reduced laminin immunoreactivity in the blood vessel wall of ageing rats correlates with reduced innervation in vivo and following transplantation. Cell Tiss. Res. 281:1995;23-32.
139. Gavazzi I., Canavan R. E. M., Cowen T. Influence of age and anti-NGF treatment on the sympathetic and sensory innervation of the rat iris. Neurosci. 73:1996;1069-1079.
140. Gavazzi I., Cowen T. Axonal regeneration from transplanted sympathetic ganglia is not impaired by age. Exp. Neurol. 122:1993;57-64.
141. Gavazzi I., Cowen T. NGF can induce a "young" pattern of innervation in transplanted old cerebral blood vessels. J. Comp. Neurol. 334:1993;489-496.
142. Gavazzi I., Cowen T. Can the neurotrophic hypothesis explain degeneration and loss of plasticity in mature and ageing autonomic nerves? J. Auton. Nerv. Syst. 58:1996;1-10.
143. Gavazzi I., Cowen T., Crutcher K. A. Lack of correlation between NGF levels and altered nerve fibre density in peripheral tissues of ageing rats. Soc. Neurosci. Abstr. 20(Part 2):1994;1710.
144. Gavazzi I., Railton K. L., Cowen T. In vivo responsiveness of sensory and sympathetic nerves to NGF in maturity and old age. Soc. Neurosci. Abstr. 21(Part 2):1995.
145. Gibbins I. L. Target-related patterns of co-existence of neuropeptide-Y, vasoactive intestinal peptide, enkephalin and substance-P in cranial parasympathetic neurons innervating the facial skin and exocrine glands of guinea pigs. Neurosci. 38:1990;541.
146. Gibbins I. L. Vasomotor, pilomotor and secretomotor neurons distinguished by size and neuropeptide content in superior cervical ganglia of mice. J. Auton. Nerv. Syst. 34:1991;171-183.
147. Gloster A., Diamond J. Sympathetic nerves in adult rats regenerate normally and restore pilomotor function during an anti-NGF treatment that prevents their collateral sprouting. J. Comp. Neurol. 326:1992;363-374.
148. Glukhova M. A., Thiery J. P. Fibronectin and integrins in development [see comments]. [Review]. Seminars in Cancer Biol. 4:1993;241-249.
149. Goedert M., Otten U., Thoenen H. Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia. Brain Res. 148:1978;264-268.
150. Gong Q. Z., Bailey M. S., Pixley S. K., Ennis M., Liu W., Shipley M. T. Localization and regulation of low affinity nerve growth factor receptor expression in the rat olfactory system during development and regeneration. J. Comp. Neurol. 344:1994;336-348.
151. Gorin P. D., Johnson E. M. J. Effect of long term nerve growth factor deprivation on the nervous system of the adult rat: an experimental autoimmune approach. Brain Res. 198:1980;27-42.
152. Greengard P., Valtorta F., Czernik A. J., Benfenati F. Synaptic vesicle phosphoproteins and regulation of synaptic function. [Review]. Science. 259:1993;780-785.
153. Greenwood D., Coggeshall R. E., Hulsebosch C. E. Sexual dimorphism in the numbers of neurons in the pelvic ganglia of adult rats. Brain Res. 340:1985;160-162.
154. Gresik E. W., Azmitia E. C. Age related changes in NGF, EGF and protease in the granular convoluted tubules of the mouse submandibular gland. A morphological and immunocytochemical study. J. Gerontol. 35:1980;520-524.
155. Grimes M. L., Zhou J., Beattie E. C., Yuen E. C., Hall D. E., Valletta J. S., Topp K. S., LaVail J. H., Bunnett N. W., Mobley W. C. Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes. J. Neurosci. 16:1996;7950-7964.
156. Grumet M., Friedlander D. R., Edelman G. M. Evidence for the binding of Ng-CAM to laminin. Cell Adhesion and Communication. 1:1993;177-190.
157. Gundersen H. J. G. Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson. J. Microsc. 143:1986;3-45.
158. Habecker B. A., Landis S. C. Noradrenergic regulation of cholinergic differentiation. Science. 264:1994;1602-1604.
159. Hamburger V. The history of the discovery of the nerve growth factor. J. Neurobiol. 24:1993;893-897.
160. Handa Y., Nojyo Y., Ishiguro H., Nagatsu I. Plasticity of the sympathetic nervous system innervating the cerebral arteries in rats. Exp. Neurol. 118:1992;324-331.
161. Harper S., Davies A. M. NGF messenger RNA expression in developing cutaneous epithelium related to innervation density. Development. 110:1990;515-519.
162. Harris L. W., Purves D. Rapid remodelling of sensory endings in the corneas of living mice. J. Neurosci. 9:1989;2210-2214.
163. Hassankhani A., Steinhelper M. E., Soonpaa M. H., Katz E. B., Taylor D. A., Andrade-Rozental A., Factor S. M., Steinberg J. J., Field L. J., Federoff H. J. Overexpression of NGF within the heart of transgenic mice causes hyperinnervation, cardiac enlargement, and hyperplasia of ectopic cells. Dev. Biol. 169:1995;309-321.
164. Heaton M. B. Influence of laminin on the responsiveness of early chick embryo neural tube neurons to nerve growth factor. J. Neurosci. Res. 22:1989;390-396.
165. Hempstead B., Martin-Zanca D., Kaplan D. R., Parada L. F., Chao M. V. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low affinity NGf receptor. Nature. 350:1991;678-683.
166. Hendry I. A. The effects of axotomy on the development of the rat superior cervical ganglion. Brain Res. 90:1975;235-244.
167. Hendry I. A. The response of adrenergic neurons to axotomy and nerve growth factor. Brain Res. 94:1975;87-97.
168. Hendry I. A., Johanson S. O., Heydon K. Retrograde axonal transport of the alpha subunit of the GTP-binding protein Gz to the nucleus of sensory neurons. Brain Res. 700:1995;157-163.
169. Hendry I. A., Johanson S. O., Heydon K. Developmental signalling. [Review]. Clin. Exp. Pharmacol. Physiol. 22:1995;563-568.
170. Hendry I. A., Stockel K., Thoenen H., Iversen L. L. The retrograde axonal transport of nerve growth factor. Brain Res. 68:1974;103-121.
171. Heumann R., Korsching S., Scott J., Thoenen H. Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissue. Embo J. 3:1984;3183-3189.
172. Heumann R. Neurotrophin signalling. Current Opinion in Neurobiol. 4:1994;668-679.
173. Heumann R., Thoenen H. Comparison between the time course of changes in nerve growth factor protein levels and those of its messenger RNA in the cultured rat iris. J. Biol. Chem. 261:1986;9246-9249.
174. Hiebert J., Smith P. G. Autonomic and sensory reinnervation of smooth muscle transplanted to the anterior chamber of the eye: effect of target postnatal age. Exp.Neurol. 127:1994;137-144.
175. Hill C. E., Vidovic M. The role of competition in the refinement of the projections of sympathetic neurons to the rat eye during development. Int. J. Dev. Neurosci. 7:1989;539-551.
176. Hirakawa N., Morimoto M., Totoki T. Sympathetic innervation of the young canine heart using anterograde and retrograde axonal tracer methods. Brain. Res Bull. 31:1993;673-680.
177. Hoyle G. W., Mercer E. H., Palmiter R. D., Brinster R. L. Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues. Neuron. 10:1993;1019-1034.
178. Hussain S., Slikker W. Jr., Ali S. F. Age-related changes in antioxidant enzyes, superoxide dismutase, catalase, glutathione peroxidase and glutathione in different regions of mouse brain. Int. J. Devl. Neurosci. 13:1995;811-817.
179. Ip N., Zigmond R. E. Long term regulation of tyrosine hydoxylase activity in the superior cervical ganglion in organ culture: effects of nerve stimulation and dexamethasone. Brain Res. 338:1985;61-70.
180. Isaacson L. G., Crutcher K. A. The duration of sprouted cerebrovascular axons following intracranial infusion of nerve growth factor. Exp. Neurol. 131:1995;174-179.
181. Isaacson L. G., Ondris D., Crutcher K. A. Plasticity of mature sensory cerebrovascular axons following intracranial infusion of nerve growth factor. J. Comp. Neurol. 361:1995;451-460.
182. Isaacson L. G., Saffran B. N., Crutcher K. A. Nerve growth factor-induced sprouting of mature, uninjured sympathetic axons. J. Comp. Neurol. 326:1992;327-336.
183. Isaacson L. G., Schwenk K. L., Billieu S. C., Crutcher K. A. Sympathetic response to intracranial NGF infusion in the absence of afferent input: axonal sprouting without neurotransmitter production. Exp. Neurol. 141:1996;57-66.
184. Ishii D. N., Glazner G. W., Pu S. F. Role of insulin-like growth factors in peripheral nerve regeneration. [Review]. Pharmacol. Ther. 62:1994;125-144.
185. Ishii D. N., Shooter E. M. Regulation of nerve growth factor synthesis in mouse submaxillary glands by testosterone. J. Neurochem. 25:1975;843-851.
186. Itoh H., Bunag R. D. Aging reduces cardiovascular and sympathetic responses to NTS injections of serotonin in rats. Exp. Gerontol. 27:1992;309-320.
187. Jaakkola S., Savunen O., Halme T., Uitto J., Peltonen J. Basement membranes during development of human nerve - schwann cells and perineurial cells display marked changes in their expression profiles for laminin subunits and beta1 and beta4 integrins. J. Neurocytol. 22:1993;215-230.
188. Jaatinen P., Hervonen A. Reactions of rat sympathetic neurons to ethanol exposure are age-dependent. Neurobiol. Aging. 15:1994;419-428.
189. James S., Patel N. J., Thomas P. K., Burnstock G. Immunocytochemical localisation of insulin receptors on rat superior cervical ganglion neurons in dissociated cell culture. J. Anat. 182:1993;95-100.
190. Jiang Z. G., Smith R. A. Effects of nerve growth factor on the survival of primary cultured adult and aged mouse sensory neurons. J. Neurosci. Res. 35:1993;29-37.
191. Jiang Z. G., Smith R. A., Neilson M. M. The effects of nerve growth factor on neurite outgrowth from cultured adult and aged mouse sensory neurons. Exp. Neurol. 130:1995;168-171.
192. Kanje M., Skottner A., Lundborg G. Effects of growth hormone treatment on the regeneration of rat sciatic nerve. Brain Res. 475:1988;254-258.
193. Kanje M., Skottner A., Lundborg G., Sjoberg J. Does insulin-like growth factor I (IGF-1) trigger the cell body reaction in the rat sciatic nerve? Brain Res. 563:1991;285-287.
194. Kanje M., Skottner A., Sjoberg J., Lundborg G. Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve. Brain Res. 486:1989;396-398.
195. Kaplan D. R., Miller F. D. Signal transduction by the neurotrophin receptors. Current Opinion in Cell Biol. 9:1997;213-221.
196. Kasayama S., Oka T. Impaired production of nerve growth factor in the submandibular gland of diabetic mice. Amer. J. Physiol. 257(P1):1989;E400.
197. Katoh-Semba R., Kaisho Y., Shintani A., Nagahama M., Kato K. Tissue distribution and immunocytochemical localization of neurotrophin-3 in the brain and peripheral tissues of rats. J. Neurochem. 66:1996;330-337.
198. Kessler J. A. Parasympathetic, sympathetic, and sensory interactions in the iris: nerve growth factor regulates cholinergic ciliary ganglion innervation in vivo. J. Neurosci. 5:1985;2719-2725.
199. Kessler J. A., Bell W. O., Black I. B. Interactions between the sympathetic and sensory innervation of the iris. J. Neurosci. 3:1983;1301-1307.
200. Klein R., Jing S., Nanduri V., Orourke E., Barbacid M. The trk protooncogene encodes a receptor for nerve growth factor. Cell. 65:1991;189-197.
201. Kojimahara M., Sekiya K., Ooneda G. Age-induced changes of cerebral arteries in rats. An electron microscope study. Virchows Archiv - A: Pathology - Pathologische Anatomie. 361:1973;11-18.
202. Korsching S. The neurotrophic factor concept - a reexamination. J. Neurosci. 13:1993;2739-2748.
203. Korsching S., Thoenen H. Nerve growth factor in sympathetic ganglia and corresponding target organs of the rat: correlation with density of sympathetic innervation. Proc. Natl. Acad. Sci. USA. 80:1983;3513-3516.
204. Kotzbauer P. T., Lampe P. A., Estus S., Milbrandt J., Johnson E. M. Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor. Neuron. 12:1994;763-773.
205. Kuchel G. A. Alterations in target innervation and collateral sprouting in the aging sympathetic nervous system. Exp. Neurol. 124:1993;381-386.
206. Kuchel G. A., Hellendall R., Blum M. Transynaptic regulation of low-affinity p75 nerve growth factor receptor messenger RNA precedes and accompanies lesion-induced collateral neuronal sprouting. Exp. Neurol. 118:1992;73-84.
207. Kuchel G. A., Rowe W., Meaney M. J., Richard C. Neurotrophin receptor and tyrosine hydroxylase gene expression in aged sympathetic neurons. Neurobiol. Aging. 18:1997;67-79.
208. Kuchel G. A., Zigmond R. E. Functional recovery and collateral neuronal sprouting examined in young and aged rats following a partial neural lesion. Brain Res. 540:1991;195-203.
209. Kuromi H. Molecules secreted from target and non-target tissues promote and repel sympathetic fiber distribution invitro. Dev. Brain. Res. 61:1991;268-270.
210. Kuromi H. Characterization of substances which promote or repel sympathetic fiber growth invitro. Neurosci. Res. 14:1992;213-225.
211. Lahtinen T. Age-dependence of the nerve fibre growth-promoting effects of hippocampus and exogenous nerve growth factor on cultured rat septum and superior cervical ganglion. Cell Differentiation Develop. 26:1989;201-209.
212. Lahtivirta S., Koistinaho J., Hervonen A. Effect of sialectomy on the superior cervical ganglion sympathetic neurons in young adult and aged mice. Mech. Ageing Dev. 62:1992;25-33.
213. Landis S. C. Target regulation of neurotransmitter phenotype [Review]. Trends Neurosci. 13:1990;344-350.
214. Larkfors L., Ebendal T., Whittemore S. R., Persson H., Hoffer B., Olson L. Decreased level of nerve growth factor (NGF) and its messenger RNA in the aged rat brain. Mol. Brain Res. 3:1987;55-60.
215. Lee K. F., Bachman K., Landis S., Jaenisch R. Dependence on p75 for innervation of some sympathetic targets. Science. 263:1994;1447-1449.
216. Lee K. F., Davies A. M., Jaenisch R. p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF. Development. 120:1994;1027-1033.
217. Lee K. F., Li E., Huber L. J., Landis S. C., Sharpe A. H., Chao M. V., Jaenisch R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 69:1992;737-749.
218. Lein P. J., Higgins D. Laminin and a basement membrane extract have different effects on axonal and dendritic outgrowths from embryonic rat sympathetic neurons in vitro. Develop. Biol. 136:1989;330-345.
219. Lentz S. I., Miner J. H., Sanes J. R., Snider W. D. Distribution of the ten known laminin chains in the pathways and targets of developing sensory neurons. J. Comp. Neurol. 378:1997;547-561.
220. Letourneau P. C., Condic M. L., Snow D. M. Interactions of developing neurons with the extracellular matrix. J. Neurosci. 14:1994;915-928.
221. Levi-Montalcini R. The nerve growth factor: 35 years later. Science. 237:1987;1154-1162.
222. Levi-Montalcini R., Angeletti P. U. Nerve growth factor. Physiol. Rev. 48:1968;534-569.
223. Lewin G. R., Barde Y.-A. Physiology of the neurotrophins. Ann. Rev. Neurosci. 19:1996;289-317.
224. Lewis M. E., Neff N. T., Contreras P. C., Stong D. B., Oppenheim R. W., Grebow P. E., Vaught J. L. Insulin-like growth factor-I: potential for treatment of motor neuronal disorders. [Review]. Exp. Neurol. 124:1993;73-88.
225. Lindholm D., Heumann R., Hengerer B., Thoenen H. Interleukin-1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts. J. Biol. Chem. 263:1988;16348-16351.
226. Lindsay R. M., Lockett C., Sternberg J., Winter J. Neuropeptide expression in cultures of adult sensory neurones: modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor. Neurosci. 33:1989;53-65.
227. Lipp J. A. M., Rudolph A. M. Sympathetic nerve development in the rat and guinea-pig heart. Biol. Neonate. 21:1972;76-82.
228. Lipton S. A. Janus faces of NF-kB: neurodestruction versus neuroprotection. Nature Medicine. 3:1997;20-22.
229. Liu D. T., Reid M. T., Bridges D. C., Rush R. A. Denervation, but not decentralization, reduces nerve growth factor content of the mesenteric artery. J. Neurochem. 66:1996;2295-2299.
230. Longo F. M., Manthorpe M., Xie Y. M., Varon S. Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism. J. Neurosci. Res. 48:1997;1-17.
231. Low P. A., Okazaki H., Dyck P. J. Splanchnic preganglionic neurons in man. I. Morphometry of preganglionic cytons. Acta Neuropathol. 40:1977;55-61.
232. Luebke J. I., Wright L. L. Characterization of superior cervical ganglion neurons that project to the submandibular glands, the eyes, and the pineal gland in rats. Brain Res. 589:1992;1-14.
233. Madeira M. D., Lieberman A. R. Sexual dimorphism in the mammalian limbic system. [Review]. Prog. Neurobiol. 45:1995;275-333.
234. Maisonpierre P. C., Belluscio L., Friedman B., Alderson R. F., Wiegand S. J., Furth M. E., Lindsay R. M., Yancopoulos G. D. NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron. 5:1990;501-509.
235. Malmfors T., Furness J. B., Campbell G. R., Burnstock G. Re-innervation of smooth muscle of the vas deferens transplanted into the anterior chamber of the eye. J. Neurobiol. 2:1971;193-207.
236. McLachlan E. M., Jang W., Devor M., Michaelis M. Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature. 363:1993;543-546.
237. Mearow K. M., Kril Y., Diamond J. Increased NGF messenger RNA expression in denervated rat skin. NeuroReport. 4:1993;351-354.
238. Mearow K. M., Kril Y., Gloster A., Diamond J. Expression of NGF receptor and gap-43 mrna in DRG neurons during collateral sprouting and regeneration of dorsal cutaneous nerves. J. Neurobiol. 25:1994;127-142.
239. Mendell, L. M. (1994) Neurotrophic factors and the specification of neural function. The Neuroscientist 1, 26-34.
240. Millaruelo A. I., Nieto Sampedro M., Cotman C. W. Cooperation between nerve growth factor and laminin or fibronectin in promoting sensory neuron survival and neuritic outgrowth. Brain Res. 466:1988;219-228.
241. Miller F. D., Mathew T. C., Toma J. G. Regulation of nerve growth factor receptor gene expression by nerve growth factor in the developing peripheral nervous system. J. Cell Biol. 112:1991;303-312.
242. Miller F. D., Speelman A., Mathew T. C., Fabian J., Chang E., Pozniak C., Toma J. G. Nerve growth factor derived from terminals selectively increases the ratio of p75 to trka NGF receptors on mature sympathetic neurons. Dev. Biol. 161:1994;206-217.
243. Mione M. C., Cavanagh J. F., Burnstock G. Uptake of 5-hydroxydopamine into non-sympathetic nerves of guinea-pig uterine artery in late pregnancy. J. Neurocytol. 22:1993;164-175.
244. Mione M. C., Cavanagh J. F. R., Lincoln J., Milner P., Burnstock G. Long-term chemical sympathectomy leads to an increase of neuropeptide Y immunoreactivity in cerebrovascular nerves and iris of the developing rat. Neurosci. 34:1990;369-378.
245. Mione M. C., Dhital K. K., Amenta F., Burnstock G. An increase in the expression of neuropeptidergic vasodilator, but not vasoconstrictor, cerebrovascular nerves in aging rats. Brain Res. 460:1988;103-113.
246. Mione M. C., Gabella G. Nerve fibres in the uterine artery increase in number in pregnant guinea-pigs. NeuroReport. 2:1991;537-540.
247. Mione, M. C., Sancesario, G., D'Angelo, V. and Bernardi, G. (1991) Increase of dopamine b-hydroxylase immunoreactivity in non-noradrenergic nerves of rat cerebral arteries following long-term sympathectomy. Neurosci. Lett. 123, 167-171.
248. Mooradian A. D., Uko-eninn A. Age-related changes in the antioxidative potential of cerebral microvessels. Brain Res. 671:1995;159-163.
249. Moore M. W., Klein R. D., Farinas I., Sauer H., Armanini M., Phillips H., Reichardt L. F., Ryan A. M., Carver-Moore K., Rosenthal A. Renal and neuronal abnormalities in mice lacking GDNF. Nature. 382:1996;76-79.
250. Murphy R. A., Acheson A., Hodges R., Haskins J., Richards C., Reklow E., Chlumecky V., Barker P. A., Alderson R. F., Lindsay R. M. Immunological relationships of NGF, BDNF, and NT-3 - recognition and functional inhibition by antibodies to NGF. J. Neurosci. 13:1993;2853-2862.
251. Navarro X., Kennedy W. R. Changes in sudomotor nerve territories with aging in the mouse. J. Auton. Nerv. Syst. 31:1990;101-107.
252. Nistico G., Ciriolo M. R., Fiskin K., Iannone M., Demartino A., Rotilio G. NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats. Free. Radical. Biol. Med. 12:1992;177-181.
253. Obremski V. J., Wood P. M., Bunge M. B. Fibroblasts promote schwann cell basal lamina deposition and elongation in the absence of neurons in culture. Dev. Biol. 160:1993;119-134.
254. O'Connor T. P., van der Kooy D. Cooperation and competition during development: neonatal lesioning of the superior cervical ganglion induces cell death of trigeminal neurons innervating the cerebral blood vessels but prevents the loss of axon collaterals from the neurons that survive. J. Neurosci. 9:1989;1490-1501.
255. Olson L., Malmfors T. Growth characteristics of adrenergic nerves in the adult rat. Acta physiol. Scand. 348(Suppl.):1970;1-111.
256. Otten U., Goedert M., Schwab M., Thibault J. Immunization of adult rats against 2.5 S NGF: effects on the peripheral sympathetic nervous system. Brain Res. 176:1979;79-90.
257. Owman, C. (1981) Pregnancy induces degenerative and regenerative changes in the autonomic innervation of the female reproductive tract. In: Development of the Autonomic Nervous System, pp. 252-279. CIBA Foundation Symposium 83. Pitman Books Ltd: London.
258. Owman, C. and Stjernquist, M. (1988) Origin, distribution and functional aspects of aminergic and peptidergic nerves in the male and female genital tract. In: Handbook of Chemical Neuroanatomy, pp. 445-544. Eds A. Bjorklund, T. Hokfelt and C. Owman. Elsevier: Amsterdam.
259. Paino C. L., Fernandezvalle C., Bates M. L., Bunge M. B. Regrowth of axons in lesioned adult rat spinal cord: promotion by implants of cultured schwann cells. J. Neurocytol. 23:1994;433-452.
260. Patterson P. H. Cytokines and the function of the mature nervous system. C.R. Acad. Sci. Paris. 316:1993;115-1157.
261. Paula-Barbosa M. M., Sousa N., Madeira M. D. Ultrastructural evidence of sexual dimorphism in supraoptic neurons: a morphometric study. J. Neurocytol. 22:1993;697-706.
262. Potter D. D., Furshpan E. J., Landis S. C. Transmitter status in cultured rat sympathetic neurons: plasticity and multiple function. Fed. Proc. 42:1983;1626-1632.
263. Purves, D. (1988) Body and Brain, A Trophic Theory of Neural Connections. Harvard University Press: Cambridge, MA.
264. Purves D., Hadley R. D., Voyvodic J. T. Dynamic changes in the dendritic geometry of individual neurons visualized over periods of up to three months in the superior cervical ganglion of living mice. J. Neurosci. 6:1986;1051-1060.
265. Purves D., Lichtman J. Geometrical differences among homologous neurons in mammals. Science. 228:1985;298-302.
266. Purves, D., White, L. E., Zheng, D., Andrews, T. J. and Riddle, D. R. (1996) Brain size, behavior and the allocation of neural space. In: The Lifespan Development of Individuals, pp. 162-178. Ed. D. Magnusson. Cambridge University Press: Cambridge, U.K.
267. Rabizadeh S., Oh J., Zhong L.-T., Yang J., Bitler C. M., Butcher L. L., Bredesen D. E. Induction of apoptosis by the low-affinity NGF receptor. Science. 261:1993;345-348.
268. Raivich G., Hellweg R., Kreutzberg G. W. NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration. Neuron. 7:1991;151-164.
269. Rao M. S., Landis S. C. Characterization of a target-derived neuronal cholinergic differentiation factor. Neuron. 5:1990;899-910.
270. Recio-Pinto E., Rechler M. M., Ishii D. N. Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J. Neurosci. 6:1986;1211-1219.
271. Reichardt L. F., Tomaselli K. J. Extracellular matrix molecules and their receptors: functions in neuronal development. Ann. Rev. Neurosci. 14:1991;531-570.
272. Reiter R. J. Oxygen radical detoxification processes during ageing: the functional importance of melatonin. Aging Clin. Exp. Res. 7:1995;340-351.
273. Ren K., Kibbey M. C., Kleinman H. K., Ruda M. A. 110/140 laminin-binding protein immunoreactivity in spinal dorsal root ganglia - a capsaicin-insensitive reduction induced by constriction injury of the sciatic nerve in rats. J. Neurosci. Res. 35:1993;227-236.
274. Rittenhouse A. R., Zigmond R. E. Nerve stimulation in vivo acutely increases tyrosine hydroxylase activity in the superior cervical ganglion and its end organs. Brain Res. 524:1990;156-159.
275. Rodriguez-Tebar A., Rohrer H. Retinoic acid induces NGF-dependent survival response and high-affinity NGF receptors in immature chick sympathetic neurons. Development. 112:1991;813-820.
276. Rohrer H., Heumann R., Thoenen H. The synthesis of nerve growth factor (NGF) is independent of innervation. Dev. Biol. 128:1988;240-244.
277. Rosenheimer J. L., Smith D. O. Age-related increase in soluble and cell surface-associated neurite outgrowth factors from rat muscle. Brain Res. 509:1990;309-320.
278. Rossino P., Gavazzi I., Timpl R., Aumailley M., Abbadini M., Giancotti F., Silengo L., Marchisio P. C., Tarone G. Nerve growth factor induces increased expression of a laminin-binding integrin in rat pheochromocytoma PC12 cells. Exp. Cell Res. 189:1990;100-108.
279. Ruit K. G., Osborne P. A., Schmidt R. E., Johnson E. M., Snider W. D. Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse. J. Neurosci. 10:1990;2412-2419.
280. Ruit K. G., Snider W. D. Administration or deprivation of nerve growth factor during development permanently alters neuronal geometry. J. Comp. Neurol. 314:1991;106-113.
281. Rush R. A., Mayo R., Zettler C. The regulation of nerve growth factor synthesis and delivery to peripheral neurons. Pharmacol. Ther. 65:1995;93-123.
282. Ryden M., Hempstead B., Ibanez C. F. Differential modulation of neuron survival during development by nerve growth factor binding to the p75 receptor. J. Biol. Chem. 272:1997;16322-16328.
283. Saba H., Cowen T., Haven A. J., Burnstock G. Uneven reduction of noradrenergic perivascular nerve densities in the left and right cerebral arteries of old rabbits. J. Cereb. Blood Flow Metab. 4:1984;284-289.
284. Saffran B. N., Woo J., Mobley W. C., Crutcher K. A. Intraventricular infusion of NGF in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth. Brain Res. 492:1989;245-254.
285. Sampath D., Jackson G. R., Werrbach-Perez K., Perez-Polo J. R. Effects of nerve growth factor on glutathione peroxidase and caatalase in PC12 cells. J. Neurochem. 62:1994;2476-2479.
286. Sandrock A. W. Jr., Matthew W. D. Substrate-bound nerve growth factor promotes neurite growth in peripheral nerve. Brain Res. 425:1987;360-363.
287. Sanes J. R. Extracellular matrix molecules that influence neural development. Ann. Rev. Neurosci. 12:1989;491-516.
288. Sanes J. R., Engvall E., Butkowski R., Hunter D. D. Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J.Cell Biol. 111:1990;1685-1699.
289. Sango K., Horie H., Inoue S., Takamura Y., Takenaka T. Age-related changes of DRG neuronal attachment to extracellular matrix proteins invitro. NeuroReport. 4:1993;663-666.
290. Santer R. M. Morphological evidence for the maintenance of the cervical sympathetic system in aged rats. Neurosci. Lett. 130:1991;248-250.
291. Santer R. M. Sympathetic neurone numbers in ganglia of young and aged rats. J. Auton. Nerv. Syst. 33:1991;221-222.
292. Santer R. M., Baker D. M. Enteric neuron numbers and sizes in Auerbach's plexus in the small and large intestine of young adult and aged rats. J. Auton. Nerv. Syst. 25:1988;59-67.
293. Scarisbrick A., Jones E. G., Isackson P. J. Coexpression of mRNAs for NGF, BDNF, and NT-3 in the cardiovascular system of the pre- and postnatal rat. J. Neurosci. 13:1993;875-893.
294. Scheff S. W., Bernardo L. S., Cotman D. W. Decrease in adrenergic axon sprouting in the senescent rat. Science. 202:1978;775-778.
295. Schmidt R. E., Beaudet L., Plurad S. B., Snider W. D., Ruit K. G. Pathologic alterations in pre- and postsynaptic elements in aged mouse sympathetic ganglia. J. Neurocytol. 24:1995;189-206.
296. Schmidt R. E., Chae H. Y., Parvin C. A., Roth K. A. Neuroaxonal dystrophy in aging human sympathetic ganglia. Amer. J. Pathol. 136:1990;1327-1338.
297. Schotzinger R. J., Landis S. C. Acquisition of cholinergic and peptidergic properties by sympathetic innervation of rat sweat glands requires interaction with normal target. Neuron. 5:1990;91-100.
298. Schwarz M. A., Mitchell M., Emerson D. L. Reconstituted basement membrane enhances neurite outgrowth in PC12 cells induced by nerve growth factor. Cell Growth. Differ. 1:1990;313-318.
299. Scott S. A., Liang S., Weingartner J. A., Crutcher K. A. Increased NGF-like activity in young but not aged rat hippocampus after septal lesions. Neurobiol. Aging. 15:1994;337-346.
300. Sebert M. E., Shooter E. M. Expression of messenger RNA for neurotrophic factors and their receptors in the rat dorsal root ganglion and sciatic nerve following nerve injury. J. Neurosci. Res. 36:1993;357-367.
301. Shelton D. L., Reichard L. F. Expression of the β-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs. Proc.Natl.Acad.Sci.USA. 81:1984;7951-7955.
302. Shelton D. L., Reichardt L. F. Studies on the regulation of β-nerve growth factor gene expression in the rat iris: the level of mRNA-encoding nerve growth factor is increased in irises placed in explant cultures in vitro, but not in irises deprived of sensory or sympathetic innervation in vivo. J. Cell Biol. 102:1986;1940-1948.
303. Siironen J., Sandberg M., Vuorinen V., Roytta M. Laminin-b1 and collagen type-IV gene expression in transected peripheral nerve - reinnervation compared to denervation. J. Neurochem. 59:1992;2184-2192.
304. Silos-Santiago I., Molliver D. C., Ozaki S., Smeyne R. J., Fagan A. M., Barbacid M., Snider W. D. Non-TrkA-expressing small DRG neurons are lost in TrkA deficient mice. J. Neurosci. 15:1995;5929-5942.
305. Slavikova J., Goldstein M., Dahlstrom A. The postnatal development of tyrosine hydroxylase immunoreactive nerves in rat atrium, studied with immunofluorescence and confocal laser scanning microscopy. J. Auton. Nerv. Syst. 43:1993;159-170.
306. Smeyne R. J., Klein R., Schnapp A., Long L. K., Bryant S., Lewin A., Lira S. A., Barbacid M. Severe sensory and sympathetic neuropathies in mice carrying a disrupted trk/NGF receptor gene. Nature. 368:1994;246-249.
307. Smith P. G. Role of the sympathetic nervous system in functional maturation of Müller's smooth muscle in the rat. J. Pharm. Exp. Ther. 235:1985;330-334.
308. Smith P. G. Functional plasticity in the sympathetic nervous system of the neonatal rat. Exp. Neurol. 91:1986;136-146.
309. Smith P. G., Beauregard C. L. Conversion of parasympathetic nerve function from prejunctional inhibition to postjunctional excitation following sympathectomy of rat periorbital smooth muscle. Brain Res. 629:1993;319-322.
310. Smith P. G., Bruckert J. W., Mills E. Reinnervation of Müller's smooth muscle by atypical sympathetic pathways following neonatal ganglionectomy in the rat: structural and functional investigations of enhanced neuroplasticity. Neuroscience. 23:1987;781-793.
311. Smith P. G., Fan Qin Sympathetic nerve trajectories to rat orbital targets: role of connective tissue pathways. J. Comp. Neurol. 365:1996;69-78.
312. Smith P. G., Venkataraman P., Reddy H. Smooth muscle growth in the mature rat: role of sympathetic innervation. J. Auton. Nerv. Syst. 31:1990;13-20.
313. Smolen A. J. Retrograde transneuronal regulation of the afferent innervation to the rat superior cervical sympathetic ganglion. J. Neurocytol. 12:1983;27-45.
314. Smolen, A. J. and Beaston-Wimmer, P. (1989) Afferent regulation of neurotransmitter metabolism in perikarya and terminals of developing sympathetic neurons. Dev. Brain Res. 50, 233-240.
315. Smolen A. J., Beaston-Wimmer P., Wright L. L., Lindley T., Cader C. Neurotransmitter synthesis, storage, and turnover in neonatally deafferented sympathetic neurons. Brain Res. 355:1985;211-218.
316. Smolen A. J., Wright L. L., Cunningham T. J. Neuron numbers in the superior cervical sympathetic ganglion of the rat: a critical comparison of methods for cell counting. J. Neurocytol. 12:1983;739-750.
317. Snider W. D. Nerve growth factor enhances dendritic arborization of sympathetic ganglion cells in developing mammals. J. Neurosci. 8:1988;2628-2634.
318. Snider W. D. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. [Review]. Cell. 77:1994;627-638.
319. Spitsbergen J. M., Stewart J. S., Tuttle J. B. Altered regulation of nerve growth factor secretion by cultured VSMCs from hypertensive rats. Amer. J. Physiol. 269:1995;H621-H628.
320. Steers W. D., Ciambotti J., Erdman S., de Groat W. C. Morphological plasticity in efferent pathways to the urinary bladder of the rat following urethral obstruction. J. Neurosci. 10:1990;1943-1951.
321. Steers W. D., Ciambotti J., Etzel B., Erdman S., de Groat W. C. Alterations in afferent pathways from the urinary bladder of the rat in response to partial urethral obstruction. J. Comp. Neurol. 310:1991;401-410.
322. Steers W. D., Kolbeck S., Creedon D., Tuttle J. B. Nerve growth factor in the urinary bladder of the adult regulates neuronal form and function. J. Clin. Invest. 88:1991;1709-1715.
323. Stevens L. M., Landis S. C. Target influences on transmitter choice by sympathetic neurons developing in the anterior chamber of the eye. Dev. Biol. 137:1990;109-124.
324. Stieg P., Stromberg I., Olson L. Effects of donor age on superior cervical ganglion transplants - evaluation by Falck-Hillarp histochemistry and immunocytochemistry. Exp. Brain. Res. 85:1991;55-65.
325. Sturrock R. R. A comparison of age-related changes in neuron number in the dorsal motor nucleus of the vagus and nucleus ambiguus of the mouse. J. Anat. 173:1990;169-176.
326. Suhonen J., Koistinaho J., Hervonen A. Histochemistry of sympathetic neurons allotransplanted from young and aged mice to the submandibular gland. Exp. Neurol. 112:1991;104-111.
327. Suhonen J., Koistinaho J., Hervonen A. Sympathetic neurons outlive the original host after transplantation to the rat submandibular gland. Neurobiol. Aging. 14:1993;383-387.
328. Suhonen J., Hervonen A. Transplanted sympathetic neurons from old rats survive in the anterior eye chamber - a histochemical and electron microscopic study. J. Neural. Transplant Plast. 4:1993;267-278.
329. Sun Y., Landis S. C., Zigmond R. E. Signals triggering the induction of leukemia inhibitory factor in sympathetic superior cervical ganglia and their nerve trunks after axonal injury. Mol. Cell Neurosci. 7:1996;152-163.
330. Sun Y., Rao M. S., Landis S. C., Zigmond R. E. Depolarization increases vasoactive intestinal peptide-like and substance-p-like immunoreactivities in cultured neonatal and adult sympathetic neurons. J. Neurosci. 12:1992;3717-3728.
331. Sun Y., Zigmond R. E. Involvement of leukemia inhibitory factor in the increases in galanin and vasoactive intestinal peptide mRNA and the decreases in neuropeptide Y and tyrosine hydroxylase mRNA in sympathetic neurons after axotomy. J. Neurochem. 67:1996;1751-1760.
332. Szeberenyi J., Erhardt P. Cellular components of nerve growth factor signaling. Biochim. Biophys. Acta. 1222:1994;187-202.
333. Taglialatela G., Hibbert C. J., Hutton L. A., Werrbach-Perez K., Perez-Polo J. R. Suppression of p140trkA does not abolish nerve growth factor-mediated rescue of serum-free PC12 cells. J. Neurochem. 66:1996;1826-1835.
334. Taglialetela G., Robinson G., Perez-Polo J. R. Inhibition of nuclear factor kappa B (NF kappa B) activity induces nerve growth factor-resistant apoptosis in PC12 cells. J. Neurosci. Res. 47:1997;155-162.
335. Takami S., Getchell M. L., Yamagishi M., Albers K. M., Getchell T. V. Enhanced extrinsic innervation of nasal and oral chemosensory mucosae in keratin 14-NGF transgenic mice. Cell Tiss. Res. 282:1995;481-491.
336. Takeda K., Gosiewska A., Peterkofsky B. Similar, but not identical, modulation of expression of extracellular matrix components during in vitro and in vivo aging of human skin fibroblasts. J. Cell Physiol. 153:1992;450-459.
337. Thoenen H. The changing scene of neurotrophic factors. Trends Neurosci. 14:1991;165-170.
338. Thoenen H. Neurotrophins and neuronal plasticity. [Review]. Science. 270:1995;593-598.
339. Thoenen H., Angeletti P. U., Levi-Montalcini R., Kettler R. Selective induction by nerve growth factor of tyrosine hydroxylase and dopamine-B-hydroxylase in the rat superior cervical ganglia. Proc. Natl. Acad. Sci. USA. 68:1971;1598-1602.
340. Thoenen H., Kettler R., Burkard W., Saner A. Neurally mediated control of enzymes involved in the synthesis of norepinephrine; are they regulated as an operational unit? Naunyn-Schmied. Arch. Pharmacol. 270:1971;146-160.
341. Thomas P. K. Growth factors and diabetic neuropathy. [Review]. Diabetic Medicine. 11:1994;732-739.
342. Thrasivoulou C., Cowen T. Regulation of rat sympathetic nerve density by target tissues and NGF in maturity and old age. Eur. J. Neurosci. 7:1995;381-387.
343. Timpl R., Dziadek M. Structure, development and molecular pathology of basement membranes. Int. Rev. Exp. Pathol. 29:1986;1-112.
344. Todd M. E. Trophic interactions between rat nerves and blood vessels in denervated peripheral arteries and in anterior eye chamber transplants. Circ. Res. 58:1986;641-652.
345. Trupp M., Ryden M., Jornvall H., Funakoshi H., Timmusk T., Arenas E., Ibanez C. F. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J. Cell Biol. 130:1995;137-148.
346. Tsai S. H., Tew J. M., Shipley M. T. Development of cerebral arterial innervation - synchronous development of neuropeptide-y (NPY)-containing and vasoactive intestinal polypeptide (VIP)-containing fibers and some observations on growth cones. Brain. Res. Dev. Brain. Res. 69:1992;77-83.
347. Tucker D. C., Askari M., Bishop S. P. Effects of sympathetic innervation on size of myocytes in embryonic rat heart cultured in-oculo. J. Mol. Cell Cardiol. 24:1992;925-935.
348. Turner C. J. Growth of sympathetic nerve terminals in the adult rat. Brain Res. 207:1981;449-452.
349. Tuttle J. B., Creedon D. J. Pharmacology of nerve growth factor output by target cells. Ann. N.Y. Acad. Sci. 692:1993;273-276.
350. Tuttle J. B., Etheridge R., Creedon D. J. Receptor-mediated stimulation and inhibition of nerve growth factor secretion by vascular smooth muscle. Exp. Cell Res. 208:1993;350-361.
351. Tuttle J. B., Steers W. D., Albo M., Nataluk E. Neural input regulates tissue NGF and growth of the adult rat urinary bladder. J. Auton. Nerv. Syst. 49:1994;147-158.
352. Uchida Y., Tomonaga M. Effects of nerve growth factor and heart cell conditioned medium on neurite regeneration of aged sympathetic neurones in culture. Brain Res. 348:1985;100-106.
353. Uchida Y., Tomonaga M. Nerve growth factor accelerates regeneration of cultured adult sympathetic ganglion cells. Age. 8:1985;19-20.
354. Uchida Y., Tomonaga M. Loss of nerve growth factor receptors in sympathetic ganglia from aged mice. Biochem. Biophys. Res. Commun. 146:1987;797-801.
355. Ursell P. C., Ren C. L., Danilo P. Anatomic distribution of autonomic neural tissue in the developing dog heart. 2. Nonadrenergic noncholinergic innervation by calcitonin gene-related peptide-immunoreactive tissue. Anat. Rec. 230:1991;531-538.
356. Van der Zee C. E. E. M., Ross G. M., Riopelle R. J., Hagg T. Survival of cholinergic forebrain neurons in developing p75 NGFR-deficient mice. Science. 274:1996;1729-1732.
357. Vega J. A., Vazquez E., Naves F. J., Del Valle M. E., Calzada B., Represa J. J. Immunohistochemical localization of the high-affinity NGF receptor (gp140-trkA) in the adult human dorsal root and sympathetic ganglia and in the nerves and sensory corpuscles supplying digital skin. Anat. Rec. 240:1994;579-588.
358. Venstrom K. A., Reichardt L. F. Extracellular matrix. 2. role of extracellular matrix molecules and their receptors in the nervous system. FASEB J. 7:1993;996-1003.
359. Vera P. L., Nadelhaft I. Afferent and sympathetic innervation of the dome and the base of the urinary bladder of the female rat. Brain Res. Bull. 29:1992;651-658.
360. Verdi J. M., Groves A. K., Farinas I., Jones K., Marchionni M. A., Reichardt L. F., Anderson D. J. A reciprocal cell-cell interaction mediated by NT-3 and neuregulins controls the early survival and development of sympathetic neuroblasts. Neuron. 16:1996;515-527.
361. Verge V. M. K., Merlio J. P., Grondin J., Ernfors P., Persson H., Riopelle R. J., Hokfelt T., Richardson P. M. Colocalization of NGF binding sites, trk messenger RNA, and low-affinity NGF receptor messenger RNA in primary sensory neurons - responses to injury and infusion of NGF. J. Neurosci. 12:1992;4011-4022.
362. Verge V. M. K., Riopelle R. J., Richardson P. M. Nerve growth factor receptors on normal and injured sensory neurons. J. Neurosci. 99:1989;14-922.
363. Vogel K. S. Development of trophic interactions in the vertebrate peripheral nervous system. [Review]. Mol. Neurobiol. 7:1993;363-382.
364. von Bartheld C. S., Kinoshita Y., Prevette D., Yin Q. W., Oppenheim R. W., Bothwell M. Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos. Neuron. 12:1994;639-654.
365. Voyvodic J. T. Development and regulation of dendrites in the rat superior cervical ganglion. J. Neurosci. 7:1987;904-912.
366. Voyvodic J. T. Peripheral target regulation of dendritic geometry in the rat superior cervical ganglion. J. Neurosci. 9:1989;1997-2010.
367. Waldhauser F., Weiszenbacher G., Tatzer E., Gisinger B., Waldhauser M., Schemper M., Frisch H. Alterations in nocturnal serum melatonin levels in humans with growth and aging. J. Clin. Endocrinol. Metab. 66:1988;648-652.
368. Warburton A. L., Santer R. M. Localisation of NADPH-diaphorase and acetylcholinesterase activities and of tyrosine hydroxylase and neuropeptide-Y immunoreactivity in neurons of the hypogastric ganglion of young adult and aged rats. J. Auton. Nerv. Syst. 45:1993;155-163.
369. Warburton A. L., Santer R. M. Decrease in synapsin I staining in the hypogastric ganglion of aged rats. Neurosci. Lett. 194:1995;157-160.
370. Warburton A. L., Santer R. M. The hypogastric and thirteenth thoracic ganglia of the rat: effects of age on the neurons and their extracellular environment. J. Anat. 190:1995;115-124.
371. Wheeler E. F., Bothwell M. Spatiotemporal patterns of expression of NGF and the low-affinity NGF receptor in rat embryos suggest functional roles in tissue morphogenesis and myogenesis. J. Neurosci. 12:1992;930-945.
372. Williams T. H., Zhang M. Q., Jew J. Y. Hypertrophy of rat sensory ganglion neurons following intestinal obstruction. Gastroenterology. 105:1993;8-14.
373. Windebank A. J., Poduslo J. F. Neuronal growth factors produced by adult peripheral nerve after injury. Brain Res. 385:1986;197-200.
374. Wright L. L., Luebke J. I., Elshaar A. E. Target-specific subpopulations of rat superior cervical ganglion neurones. J. Auton. Nerv. Syst. 33:1991;105-106.
375. Wright L. L., Smolen A. J. Neonatal testosterone treatment increases neuron and synapse numbers in male rat superior cervical ganglion. Brain Res. 284:1983;145-153.
376. Wright L. L., Smolen A. J. The role of neuron death in the development of the gender difference in the number of neurons in the rat superior cervical ganglion. Int. J. Devl. Neuroscience. 5:1987;305-311.
377. Wuarin L., Guertin D. M., Ishii D. N. Early reduction in insulin-like growth factor gene expression in diabetic nerve. Exp. Neurol. 130:1994;106-114.
378. Wyatt S., Davies A. M. Regulation of expression of mRNAs encoding the nerve growth factor receptors p75 and trka in developing sensory neurons. Development. 119:1993;635-648.
379. Wyatt S., Davies A. M. Regulation of nerve growth factor receptor gene expression in sympathetic neurons during development. J. Cell Biol. 130:1993;1435-1446.
380. Yamamoto M., Sobue G., Li M., Arakawa Y., Mitsuma T., Kimata K. Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and low-affinity nerve growth factor receptor (LNGFR) messenger RNA levels in cultured rat schwann cells - differential time-dependent and dose-dependent regulation by cAMP. Neurosci. Lett. 152:1993;37-40.
381. Yancopoulos G. D., Maisonpierre P. C., Ip N. Y., Aldrich T. H., Belluscio L., Boulton T. G., Cobb M. H., Squinto S. P., Furth M. E. Neurotrophic factors, their receptors, and the signal transduction pathways they activate. Cold Spring Harbour Symposium on Quantitative Biology. 55:1990;371-379.
382. Yawo H. Changes in the dendritic geometry of mouse superior cervical ganglion cells following postganglionic axotomy. J. Neurosci. 7:1987;3703-3711.
383. Yoshida K., Gage F. H. Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines. Brain Res. 569:1992;14-25.
384. Zettler C., Head R. J., Rush R. A. Chronic nerve growth factor treatment of normotensive rats. Brain Res. 538:1991;251-262.
385. Zettler C., Rush R. A. Elevated concentrations of nerve growth factor in heart and mesenteric arteries of spontaneously hypertensive rats. Brain Res. 614:1993;15-20.
386. Zhang Z. Y., Tarone G., Turner D. C. Expression of integrin-alpha1beta1 is regulated by nerve growth factor and dexamethasone in PC12 cells - functional consequences for adhesion and neurite outgrowth. J. Biol. Chem. 268:1993;5557-5565.
387. Zhou X.-F., Rush R. A. Sympathetic neurons in neonatal rats require endogenous neurotrophin-3 for survival. J. Neurosci. 15:1995;6521-6530.
388. Zhou X. F., Rush R. A. Functional roles of neurotrophin 3 in the developing and mature sympathetic nervous system. Mol. Neurobiol. 13:1996;185-197.
389. Zigmond R. E., Baldwin C., Hyattsachs H., Rittenhouse A., Sasek C., Schwarzschild M. A. Regulation of catecholamine biosynthesis in sympathetic neurones by neuropeptides and by depolarization. J. Auton. Nerv. Syst. 33:1991;120-121.
390. Zigmond R. E., Hyattsachs H., Baldwin C., Qu X. M., Sun Y., Mckeon T. W., Schreiber R. C., Vaidyanathan U. Phenotypic plasticity in adult sympathetic neurons - changes in neuropeptide expression in organ culture. Proc. Natl. Acad. Sci. USA. 89:1992;1507-1511.