Bone turnover is reduced in children with juvenile rheumatoid arthritis

Journal of Endocrinological Investigation

Volumn 21, Issue 1, 1998, Pages 31-36

  Falcini, F ^a,c   Ermini, M ^a   Bagnoli, F ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c NONE   (Italy)

Author keywords

JRA bone turnover; JRA osteoporosis; Juvenile rheumatoid arthritis

Indexed keywords

ALKALINE PHOSPHATASE; CALCIFEDIOL; CALCITRIOL; CALCIUM ION; CARBOXYTERMINAL PROPEPTIDE; CARBOXYTERMINAL TELOPEPTIDE; COLLAGEN TYPE 1; MAGNESIUM ION; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; OSTEOCALCIN; PARATHYROID HORMONE; PEPTIDE; PHOSPHORUS; STEROID; UNCLASSIFIED DRUG;

ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BONE DESTRUCTION; BONE METABOLISM; BONE TURNOVER; CALCIUM BLOOD LEVEL; CHILD; CLINICAL ARTICLE; COLLAGEN DEGRADATION; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; MAGNESIUM BLOOD LEVEL; MALE; OSSIFICATION; OSTEOLYSIS; OSTEOPOROSIS; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; REMISSION;

EID: 0031937806     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03347283     Document Type: Article

References (34)

1. Hopp R., Degan J.A., Gallagher J.C., Cassidy J.T. Estimation of bone mineral density in children with juvenile rheumatoid arthritis. J. Rheumatol. 18: 1235, 1991.
2. Cassidy J.T., Petty R.E. Juvenile rheumatoid arthritis. In: Cassidy J.T., Petty R.E. (Eds.), Textbook of pediatric rheumatology. Churchill Livingstone, New York, 1990, p. 113.
3. Elsasser U., Wilkins B., Hesp R., Thurnham D.I., Reeve J., Ansell B.M. Bone rarefaction and crush fractures in juvenile chronic arthritis. Arch. Dis. Child. 57: 377, 1982.
4. Brewer E.J. Jr., Giannini E.H. Standard methodology for segment I, II and III pediatric rheumatology collaborative study group studies. I. Design. J. Rheumatol. 9: 109, 1982.
5. Giannini E.H., Brewer E.J. Jr. Standard methodology for segment I, II and III pediatric rheumatology collaborative study group studies. II. Analysis and presentation of data. J. Rheumatol. 9: 1144, 1982.
6. Mundy G.R. Immune system and bone remodelling. Trends Endocrinol. Metab. 1: 307, 1990.
7. Bouxsein M.L., Marcus R. Overview of exercise and bone mass. Clin. North Am. 20: 787, 1994.
8. Bacon M.C., White P.H., Raiten D.J. Nutritional status and growth in juvenile rheumatoid arthritis? Semin. Arthrithis Rheum. 20: 97, 1990.
9. Suskind D., Murthy K.K., Suskind R.M. The malnourished child: an over review. Nestlé Nutrition Workshop Series. Nestec, Ltd. Raven Press, New York, 19: 1, 1990.
10. Joffe I., Epstein S. Osteoporosis associated with rheumatoid arthritis: pathogenesis and management. Semin. Arthritis Rheum. 20: 256, 1991.
11. Als O.S., Gotfredsen A., Christiansen C. The effect of glucocorticoids on bone mass in rheumatoid arthritis patients. Arthritis Rheum. 28: 369, 1985.
12. Reed A., Haughen M., Pachman L.M., Langman C.B. Abnormalities in serum osteocalcin values in children with chronic rheumatic diseases. J. Pediatr. 116: 574, 1990.
13. Bianchi M.L., Bardare M., Caraceni M.P., Cohen E., Falvella S., Borzani M., De Gaspari M.G. Bone metabolism in juvenile rheumatoid arthritis. Bone Miner. 9: 153, 1990.
14. Reed A., Haughen M., Pachman LM., Langman CB. 25-hydroxyvitamin D therapy in children with active juvenile rheumatoid arthritis: short-term effects on serum osteocalcin levels and bone mineral density. J. Pediatr. 119: 657, 1991.
15. Reed A., Haugen M., Pachman L., Langman C. Repair of osteopenia in children with juvenile rheumatoid arthritis. J. Pediatr. 122: 693, 1993.
16. Hillman L., Cassidy J.T., Johnson L., Lee D., Allen S.H. Vitamin D metabolism and bone mineralization in children with juvenile rheumatoid arthritis. J. Pediatr. 124: 9104, 1994.
17. Pepmueller P.H., Cassidy J.T., Allen S.H., and Hillman L.S. Bone mineralization and bone mineral metabolism in children with juvenile rheumatoid athritis. Arthritis Rheum. 39: 746, 1996.
18. Cecchettin M., Tarquini B., Manente P., Conte N., Albertini A. Serum osteocalcin assay and its clinical application. In: Cecchettin M., Segre G. (Eds.), Calciotropic hormones and calcium metabolism. Excerpta Medica, Amsterdam, 1986, p 7.
19. Risteli J., Melkko J., Niemi S., Risteli L. Use of a marker of collagen formation in osteoporosis studies. Calcif. Tissue Int. 49 (Suppl.): 24, 1991.
20. Risteli J., Niemi S., Elomaa I., Risteli L. Bone resorption assay based on a peptide liberated during type I collagen degradation. J. Bone Miner Res. 6 (Suppl 1): S251, 1991.
21. EULAR standing Committee on Pediatric Rheumatology. Moscow, June 22, 1983.
22. Nishimoto S.K., Price P.A. Proof that the γ-carboxyglutamic acid-containing bone protein is synthesized in calf bone. J. Biol. Chem. 254: 437, 1979.
23. Hauschka P.V., Frenkel J., De Muth R., Gundberg C.M. Presence of osteocalcin and related higher molecular weight γ-carboxyglutamic acid-containing proteins in developing bone. J. Biol. Chem. 258: 176, 1983.
24. Carmel R., Lau K.H.W., Baylink D.J., Saxena S., Singer F.R. Cobalamin and osteoblast-specific proteins. N. Engl. J. Med. 319: 70, 1988.
25. Falcini F., Trapani S., Civinini R., Capone A., Ermini M., Bartolozzi G. The primary role of steroids on the osteoporosis in juvenile rheumatoid arthritis patients evaluated by dual energy X-ray absorptiometry. J. Endocrinol. Invest. 19: 165, 1996.
26. Luckert B.P., Higgins J.C., Stoskops M.M. Serum osteocalcin is increased in patients with hyperthyroidism and decreased in patients receiving glucocorticoids. J. Clin. Endocrinol. Metab. 62: 1056, 1986.
27. Sambrook P.N., Eisman J.A., Champion G.D., Yeates M.G., Pocock N.A., Eberl S. Determinants of axial bone loss in rheumatoid arthritis. Arthritis Rheum. 30: 721, 1987.
28. Barden H.S., Mazess R.B. Bone densitometry in infants. J. Pediatr. 113: 172, 1988.
29. Pettipher E.R., Henderson B., Edwards J.C., Higgs G.A. Effect of indomethacin on swelling, lymphocyte influx, and cartilage proteoglycan depletion in experimental arthritis. Ann. Rheum Dis. 48: 623, 1989.
30. Kikuchi K., Ihn H., Sato S., Igarashi A., Soma Y., Ishibashi Y., Takehara K. Serum concentration of procollagen type I carboxyterminal propeptide in systemic sclerosis. Arch. Dermatol. Res. 286: 77, 1994.
31. Risteli J., Elomaa I., Niemi S., Novamo A., Risteli L. Radioimmunoassay for the Pyridinoline Cross Linked Carboxy-Terminal Telopeptide of Type 1 Collagen; A new serum marker of bone collagen degradation. Clin. Chem. 39: 635, 1993.
32. Eriksen E.F., Charles P., Melsen F. Mosekilde L., Risteli L., Risteli J. Serum markers of type 1 collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry. Bone Miner. Res. 8: 127, 1993.
33. Lepore L., Pennesi M., Longo F., Lucchesi A. Serum cytokines levels in polyarticular and in systemic juvenile chronic arthritis. Clin. Exp. Rheumatol. 1: S-9, 1993.
34. May K.P., West S.G., Mc Dermott M.T., Huffer W.E. The effect of low dose methotrexate on bone metabolism and histomorphometry in rats. Arthritis Rheum. 37: 201, 1994.