Differential expression of CD44v6 in metastases of intestinal and diffuse types of gastric carcinoma

Journal of Clinical Pathology

Volumn 51, Issue 2, 1998, Pages 134-137

  Castella E M ^a   Ariza, A ^a   Pellicer, I ^a   Fernandez Vasalo A ^a   Ojanguren, I ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

CD44; Diffuse carcinoma; Gastric adenocarcinoma; Immunohistochemistry; Intestinal carcinoma; Invasion; Metastasis

Indexed keywords

CD44V ANTIGEN; CELL ADHESION MOLECULE;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; EXON; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CARCINOMA; STOMACH MUCOSA;

EID: 0031937661     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.51.2.134     Document Type: Article

References (16)

1. Fox SB, Fawcett J, Jackson DG, et al. Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms. Cancer Res 1994;54:4539-46.
2. Picker LJ, Nackache M, Butcher EC. Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types. J Cell Biol 1989;109:927-37.
3. Denning SM, Le PT, Singer KH, et al. Antibodies against the CD44 p80, lymphocyte homing receptor augment human peripheral blood T cell activation. J Immunol 1990; 144:7-15.
4. Lesley J, Hyman R, Kinkade PW. CD44 and its interaction with the extracellular matrix. Adv Immunol 1993;54:271-335.
5. Herrlich P, Zoller M, Pals ST, et al. CD44 splice variants: metastases meet lymphocytes. Immunol Today 1993;14: 395-9.
6. Günthert U, Hofmann M, Wolfgang R, et al. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991;65:13-24.
7. Hofmann M, Rudy W, Zöller M, et al. CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines. Cancer Res 1991; 51:5292-7.
8. Seiter S, Arch R, Reber S, et al. Prevention of tumor metastasis formation by antivariant CD44. J Exp Med 1993;177: 433-55.
9. Heider KH, Dämmrich J, Skroh-Angel P, et al. Differential expression of CD44 splice variants in intestinal and diffuse-type human gastric carcinomas and normal gastric mucosa.Cancer Res 1993;53:4197-203.
10. Washington K, Gottfried MR, Telen MJ. Expression of the cell adhesion molecule CD44 m gastric adenocarcinoma. Hum Pathol 1994;25:1043-9.
11. Mayer B, Jauch KW, Günthert U, et al. De-novo expression of CD44 and survival in gastric cancer. Lancet 1993;342: 1019-22.
12. Wielenga VJM, Heider KH, Offerhaus GJA, et al. Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. Cancer Res 1993;53:4754-6.
13. Ristamäki R, Joensuu H, Söderström K, et al. CD44v6 expression in non-Hodgkin lymphoma: an association with low histological grade and poor prognosis. J Pathol 1995;176:259-67.
14. Kaufmann M, Heider KJ, Sinn HP, et al. CD44 variant exon epitopes in primary breast cancer and length of survival. Lancet 1995;345:615-19.
15. Mulder JW, Kruyt PM, Sewnath M, et al. Colorectal cancer prognosis and expression of v6-containing CD44 proteins. Lancet 1994:334:1470-2.
16. Dammrich J, Vollmers HP, Heider KH, et al. Importance of different CD44v6 expression in human gastric intestinal and diffuse type cancers for metastatic lymphogenic spreading. J Mol Med 1995;73:395-401.