Dexamethasone in the diagnostic work-up of growth hormone deficiency

Clinical Endocrinology

Volumn 48, Issue 2, 1998, Pages 223-228

  Pellini, Cristina ^a   De Angelis, Riccardo ^a   Di Natale, Berardo ^a,b   Lukezic, Monica ^a   Mora, Stefano ^a   Chiumello, Giuseppe ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; DEXAMETHASONE; GROWTH HORMONE; MONOCOMPONENT INSULIN; NEUTRAL INSULIN;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; CHILD; DIAGNOSTIC ACCURACY; DIAGNOSTIC APPROACH ROUTE; FEMALE; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE DEFICIENCY; GROWTH HORMONE RELEASE; HORMONAL REGULATION; HUMAN; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0031937069     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1998.3841202.x     Document Type: Article

References (28)

1. Adams, E.F., Brajkovich, I.E. & Mashiter, K. (1981) Growth hormone and prolactin secretion by dispersed cell cultures of human pituitary adenomas: long-term effects of hydrocortisone. estradiol, insulin, 3,5,3′-triiodothyronine and thyroxine. Journal of Clinical Endocrinology and Metabolism, 53, 381-386.
2. Bridson, W.E. & Kohler, P.O. (1970) Cortisol stimulation of growth hormone production by human pituitary tissue in culture. Journal of Clinical Endocrinology and Metabolism, 30, 538-543.
3. Brook, C.G.D. & Hindmarsh, P.C. (1991) Tests for growth hormone secretion. Archives of Disease in Childhood, 66, 85-87.
4. Burguera, B., Muruais, C., Penalva, A., Dieguez, C. & Casanueva, F.F. (1990) Dual and selective actions of glucocorticoids upon basal and stimulated growth hormone release in man. Neuroendocrinology, 51, 51-58.
5. Casanueva, F.F., Burguera, B., Muruais, C. & Dieguez, C. (1990) Acute administration of corticoids: a new and peculiar stimulus of growth hormone secretion in man. Journal of Clinical Endocrinology and Metabolism, 70, 234-237.
6. Casanueva, F.F., Burguera, B., Tome, M.A., Lima, L., Tresguerres, J.A.F., Devesa, J. & Dieguez, C. (1988) Depending on the time of administration, dexamethasone potentiates or blocks growth hormone-releasing hormone-induced growth hormone release in man. Neuroendocrinology, 47, 46-49.
7. Ceda, G.P., Davis, R.G. & Hoffman, A.R. (1987) Glucocorticoid modulation of growth hormone secretion in vitro. Evidence for a biphasic effect on GH-releasing hormone mediated release. Acta Endocrinologica (Copenh). 114, 465-469.
8. De Kloet, E.R. & Reul, J.M.H.M. (1987) Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems. Psychoneuroendocrinology, 12, 83-105.
9. Devesa, J., Lima, L. & Tresguerres, J.A.F. (1992) Neuroendocrine control of growth hormone secretion in humans. Trends in Endocrinology and Metabolism, 3, 175-183.
10. Greulich, W.W. & Pyle, S.I. (1959) Radiographic Atlas of Skeletal Development of the Hand and Wrist. Second edition. Stanford University Press, Stanford.
11. Hindmarsh, P.C. & Swift, P.G.F. (1995) An assessment of growth hormone provocation tests. Archives of Disease in Childhood. 72, 362-368.
12. Lima, L., Arce, V., Diaz, M.J., Tresguerres, J.A.F. & Devesa, J. (1993) Glucocorticoids may inhibit growth hormone release by enhancing B-Adrenergic responsiveness in hypothalamic somatostatin neurons. Journal of Clinical Endocrinology and Metabolism, 76, 439-444.
13. Martial, J.A., Seeburg, P.H., Guenzi, D., Goodman, H.M. & Baxter, J.D. (1977) Regulation of growth hormone gene expression: synergistic effects of thyroid and giucocorticoid hormones. Proceedings of the National Academy of Sciences USA, 74, 4293-4295.
14. Martul, P., Pineda, J., Dieguez, C. & Casanueva, F.F. (1992) Corticoid-induced growth hormone (GH) secretion in GH-deficient and normal children. Journal of Clinical Endocrinology and Metabolism. 75, 536-539.
15. Mulchachey, J.J., Di Blasio, A.M. & Jaffe, R.B. (1988) Effect of growth hormone (GH) releasing hormone and somatostatin on GH secretion from individual human and monkey fetal anterior pituitary cells: modulation by thyroid hormone and glucocorticoids. Journal of Clinical Endocrinology and Metabolism, 60, 395-400.
16. Muruais, C., Cordido, F., Morales, M.J., Casanueva, F.F. & Dieguez, C. (1991) Corticosteroid-induced growth hormone secretion in normal and obese subjects. Clinical Endocrinology, 35, 485-490.
17. Nakagawa, K., Ishizuka, T., Obara, T., Matsubara, M. & Akikawa, K. (1987) Dichotomic action of glucocorticoids on growth hormone secretion. Acta Endocrinologica (Copenh). 116, 165-171.
18. Nyborg, J.K., Nguyen, A.P. & Spindler, S.R. (1984) Relationship between thyroid and glucocorticoid hormone gene transcription and mRNA accumulation. Journal of Biological Chemistry. 259, 12377-12381.
19. Onigata, K., Yagi, H., Yutani, S., Nagashima, K. & Kuroume, T. (1992) Growth hormone secretion induced by dexamethasone in children with short stature. Proceedings of the International Symposium Growth and Growth Disorders, The Hague: 52.
20. Pineda, J., Martul, P., Casanueva, F.F., Dieguez, C., Rica, I. & Loridan, L. (1994) Oral dexamethasone administrative new pharmacological test for the assessment of growth hormone secretion. European Journal of Endocrinology, 131, 598-601.
21. Rosenfeld, R.G., Albertsson-Wikland, K., Cassorla, F., Frasier, S.D., Hasegawa, Y., Hintz, R.L., Lafranchi, S., Lippe, B., Loriaux, L., Melmed, S., Preece, M.A., Ranke, M.B., Reiter, E.O., Rogol, A.D., Underwood, L.E. & Werther, G.A. (1995) Diagnostic controversy: the diagnosis of childhood growth hormone deficiency revisited. Journal of Clinical Endocrinology and Metabolism. 80, 1532-1540.
22. Seifert, H., Perrin, M., Rivier, J. & Vale, W. (1985) Growth hormone-releasing factor binding sites in rat anterior pituitary membrane homogenates: modulation by glucocorticoids. Endocrinology, 117, 424-426.
23. Shah, A., Stanhope, R. & Matthew, D. (1992) Hazards of pharmacological tests of growth hormone secretion in childhood. British Medical Journal. 304, 173-174.
24. Tanner, J.M. & Whitehouse, R.H. (1976) Clinical longitudinal standard for height, weight, height velocity, weight velocity and stages of puberty. Archives of Disease in Childhood, 51, 170-179.
25. Thakore, J.H. & Dinan, T.G. (1995) Diurnal variation of growth hormone responses to acutely administered dexamethasone in healthy male volunteers. Hormone Metabolism Research, 27, 23-25.
26. Vale, W., Vaughun, G., Yamamoto, G., Spiess, J. & Rivier, J. (1983) Effects of synthetic human pancreatic (tumor) GH releasing factor and somatostatin, triiodothyronine and dexamethasone on GH secretion in vitro. Endocrinology, 112, 1553-1555.
27. Wehrenberg, W.B., Baird, A. & Ling, N. (1983) Potent interaction between glucocorticoids and growth hormone releasing factor in vivo. Science, 221, 556-558.
28. Wehrenberg, W.B., Janowski, B.A., Piering, A.W., Culler, F. & Jones, K.L. (1990) Glucocorticoids: potent inhibitors and stimulators of growth hormone secretion. Endocrinology, 126, 3200-3203.