Gender, autoantibodies, and obesity in newly diagnosed diabetic patients aged 40-75 years

Diabetes Care

Volumn 21, Issue 2, 1998, Pages 250-255

  Wroblewski, Marek ^a   Gottsater, Anders ^a   Lindgarde, Folke ^a   Fernlund, Per ^a   Sundkvist, Goran ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; ENZYME ANTIBODY; GLUTAMATE DECARBOXYLASE; PANCREAS ISLET CELL ANTIBODY;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CLINICAL FEATURE; FEMALE; HUMAN; INCIDENCE; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; REFERENCE VALUE; SEX DIFFERENCE;

EID: 0031936910     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.21.2.250     Document Type: Article

References (32)

1. Melton LJ III, Palumbo PJ, Chu C-P: Incidence of diabetes mellitus by clinical type. Diabetes Care 6:75-86, 1983
2. Laakso M, Pyörälä K: Age of onset and type of diabetes. Diabetes Care 8:114-117, 1985
3. Molback AG, Christau B, Marner B, Borch-Johnsen K, Nerup J: Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark. Diabet Med 11:650-655, 1994
4. Dahlquist G, Blom L, Holmgren G, Hägglöf B, Larsson Y, Sterky G, Wall S: The epidemiology of diabetes in Swedish children 0-14 years. Diabetologia 28:802-808, 1985
5. Östman J, Arnqvist H, Blohmé G, Lithner F, Littorin B, Nyström L, Sandström A, Scherstén B, Wall S, Wibell L: Epidemiology of diabetes mellitus in Sweden: results of the first year of a prospective study in the population age group 15-34 years. Acta Med Scand 220:437-445, 1986
6. Landin-Olsson M, Karlsson A, Dahlquist G, Blom L, Lernmark Å, Sundkvist G: Islet cell and other organ-specific autoantibodies in all children developing type 1 (insulin dependent) diabetes in Sweden during one year and in matched control children. Diabetologia 32:387-395, 1989
7. 35S] GAD 65-ligand binding assay. Clin Chem 43:779-785, 1997
8. Landin-Olsson M, Nilsson K-O, Lernmark A, Sundkvist G: Islet cell antibodies and fasting C-peptide predict insulin requirement at diagnosis of diabetes mellitus. Diabetologia 33:561-568, 1990
9. Landin-Olsson M, Karlsson FA, Lernmark Å, Sundkvist G, the Diabetes Incidence Study in Sweden Group: Islet cell and thyrogastric antibodies in 633 consecutive 15-to 34-yr-old patients in the Diabetes Incidence Study in Sweden. Diabetes 41:1022-1027, 1992
10. Hagopian WA, Karlsen AK, Gottsäter A, Landin-Olsson M, Grubin CE, Sundkvist G, Petersen JS, Boel E, Dyrberg T, Lernmark Å: Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD-65) shows 65 K autoantibody positivity at onset predicts diabetes type. J Clin Invest 91:368-374, 1993
11. Tuomi T, Groop LC, Zimmet PZ, Rowley MJ, Knowles W, Mackay IR: Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of disease. Diabetes 42:359-362, 1993
12. Gottsäter A, Landin-Olsson M, Fernlund P, Lernmark Å, Sundkvist G: β-cell function in relation to islet cell antibodies during the first 3 yr after clinical diagnosis of diabetes in type II diabetic patients. Diabetes Care 16:902-910, 1993
13. Gottsäter A, Landin-Olsson M, Lernmark Å, Fernlund P, Sundkvist G: Islet cell antibodies are associated with β-cell failure also in obese adult onset diabetic patients. Acta Diabetol 31:226-231, 1994
14. World Health Organization: Diabetes Mellitus: Report of a WHO Study Group. Geneva, World Health Org., 1985 (Tech. Rep. Ser., no. 727)
15. National Diabetes Data Group: Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28:1039-1057, 1979
16. Lillioja S, Mott DM, Spraul M, Ferraro R, Foley JE, Ravussin E, Knowler WC, Bennett PH, Bogardus C: Insulin resistance and insulin secretory dysfunction as precursors of non-insulin dependent diabetes mellitus: prospective studies of Pima Indians. N Engl J Med 329:1988-1992, 1993
17. Haffner SM, Miettinen H, Gaskill SP, Stern MP: Decreased insulin secretion and increased insulin resistance are independently related to the 7-year risk of NIDDM in Mexican-Americans. Diabetes 44:1386-1391, 1995
18. Abate N: Insulin resistance and obesity: the role of fat distribution pattern. Diabetes Care 19:292-294, 1996
19. 1c by a new liquid-chromatographic assay. Clin Chem 32:1867-72, 1986
20. Heding LS: Radioimmunological determination of C-peptide in serum. Diabetologia 11:544-548, 1975
21. Landin-Olsson M, Sundkvist G, Lernmark Å: Prolonged incubation on the two-color immunofluorescent test increases the prevalence and titres of islet cell antiobidies in type 1 diabetes mellitus. Diabetologia 30:327-332, 1987
22. Boiltard C, Bonifacio E, Botazzo GF, Gleishmann H, Molenaar J: Immunology and Diabetes Workshop: Report on the Third International Workshop on the Standardisation of Cytoplasmic Islet Cell Antibodies. Diabetologia 31:451-452, 1983
23. Clauson P, Linnarsson R, Gottsäter A, Sundkvist G, Grill V: Relationships between diabetes duration, metabolic control and β-cell function in a representative population of type 2 diabetic patients in Sweden. Diabet Med 11:794-801, 1994
24. Falorni A, Grubin CE, Takei I, Shimada A, Kasuga A, Maruyama T, Ozawa Y, Kasatani T, Saruta T, Li L: Radioimmunoassay detects the frequent occurrence of autoantibodies to the Mr 65,000 isoform of glutamic acid decarboxylase in Japanese insulin-dependent diabetes. Autoimmunity 19:113-125, 1994
25. Grubin CE, Daniels T, Toivola B, Landin-Olsson M, Hagopian WA, Li L, Karlsen AE, Boel E, Michelsen B, Lernmark Å: A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetologia 37:344-350, 1994
26. Eriksson KF, Lindgärde F: Prevention of type 2 diabetes mellitus by diet and physical exercise. Diabetologia 34:891-898, 1991
27. Gottsäter A, Landin-Olsson M, Lernmark Å, Fernlund P, Sundkvist G, Hagopian WA: Glutamate decarboxylase autoantibody levels predict the rate of β-cell decline in adult-onset diabetes. Diabetes Res Clin Pract 27:133-140, 1995
28. Eriksson J, Forsen B, Häggblom M, Teppo A-M, Groop L: Clinical and metabolic characteristics of type 1 and type 2 diabetes. Diabet Med 9:654-660, 1992
29. Andersson DGK, Svärdsudd K, Tibblin G: Prevalence and incidence of diabetes in a Swedish community 1972-1987. Diabet Med 8:428-434, 1991
30. Welborn TA, Glatthaar Ch, Whittall D, Bennett S: An estimate of diabetes prevalence from a national population sample: a male excess. Med J Australia 150:78-91, 1989
31. Blohmé G, Nystrom L, Arnqvist HJ, Lithner F, Littorin B, Olsson PO, Schersten B, Wibell L, Ostman J: Male predominance of type 1 insulin dependent diabetes mellitus in young adults. Diabetologia 35:55-62, 1992
32. Niskanen LK, Uusitupa MI, Sarlund H, Siitonen O, Pyörälä K: Five-year follow up study on plasma insulin levels in newly diagnosed NIDDM patients and nondiabetic subjects. Diabetes Care 13:41-48, 1990