Using capillary electrophoresis/frontal analysis to screen drugs interacting with human serum proteins

Electrophoresis

Volumn 19, Issue 3, 1998, Pages 448-454

  McDonnell, Patricia A ^a   Caldwell, Gary W ^a   Masucci, John A ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

Capillary electrophoresis; Frontal analysis; Serum protein binding; Blockers

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; LIPOPROTEINS;

BLOCKINGS; DRUG CONCENTRATION; FRONTAL ANALYSIS; HIGH DENSITY LIPOPROTEIN; HUMAN SERUM ALBUMINS; PROTEIN MIXTURES; PROTEIN-BINDING; SERUM PROTEIN BINDING; SERUM PROTEINS; Β-BLOCKER;

CAPILLARY ELECTROPHORESIS;

ACEBUTOLOL; ALPRENOLOL; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; HIGH DENSITY LIPOPROTEIN; HUMAN SERUM ALBUMIN; LOW DENSITY LIPOPROTEIN; METOPROLOL; OROSOMUCOID; OXPRENOLOL; PINDOLOL; PROPRANOLOL; TIMOLOL;

ARTICLE; AUTOMATION; BINDING AFFINITY; CALIBRATION; CAPILLARY ELECTROPHORESIS; DRUG BINDING; HUMAN; IN VITRO STUDY; MOLECULAR WEIGHT; PLASMA PROTEIN BINDING; SCREENING; TECHNIQUE;

EID: 0031936330     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.1150190315     Document Type: Article

References (33)

1. Moos, W. H., Green, G. D., Annu. Rep. Med. Chem. 1993, 28, 315-324.
2. Vailner, J. J., J. Pharm. Sci. 1977, 66, 447-465.
3. Li, K. L., Thakur, A. K., Kapoor, A. L., J. Pharm. Sci. 1988, 77, 251-254.
4. Chignell, C. F., in: Garrett, E. R., Hirtz, J. L. (Eds.), Drug Fate and Metabolism, Marcel Dekker, New York 1977, Chapter 5.
5. Bowers, W. F., Fulton, S., Thompson, J., Clin. Pharmacokinet. 1984, 9, 49-60.
6. Nichol, L. W., Winzor, D. J., J. Physiol. Chem. 1964, 68, 2455.
7. Ascoli, G., Bertucci, C., Salvadori, P., J. Pharm. Sci. 1995, 84, 737-741.
8. Alexander, K. A., Phelps, W. C., Biochemistry 1996, 55, 9864-9872.
9. Tanaka, M., Asahi, Y., Masuda, S., Ota, T., Chem. Pharm. Bull. 1991, 39, 1-4.
10. Noctor, T. A. G., Diaz-Perez, J., Wainer, I. W., J. Pharm. Sci. 1993, 82, 675-676.
11. Hermansson, J. J., J. Chromatogr. 1983, 269, 71-80.
12. Jewell, R. C., Brouwer, K. L. R., McNamara, P. J., J. Chromatogr. 1989, 487, 257-264.
13. Pinkerton, T. C., Miller, T. D., Janis, L. J., Anal. Chem. 1989, 61, 1171-1174.
14. Shibukawa, A., Nishimura, N., Nomura, K., Kuroda, Y., Nakagawa, T., Chem. Pharm. Bull. 1990, 38, 443-447.
15. Chu, Y.-H., Avila, L. Z., Gao, J., Whitesides, G. M., Acc. Chem. Res. 1995, 28, 461-468.
16. Kraak, J. C., Busch, S., Poppe, H., J. Chromatogr. 1992, 608, 257-264.
17. Shibukawa, A., Yoshimoto, Y., Ohara, T., Nakagawa, T., Pharm. Sci. 1994, 83, 616-619.
18. Ohara, T., Shibukawa, A., Nakagawa, T., Anal. Chem. 1995, 67, 3520-3525.
19. Belpaire, F. M., Bogaert, M. G., Rosseneu, M., Eur. J. Clin. Pharmacol. 1982, 22, 253-256.
20. Glason, S., Zini, R., D'Athis, P., Tillement, J.-P., Boissier, J. R., Mol. Pharm. 1980, 17, 187-191.
21. Reif, W., Lausch, R., Freitag, R., Adv. Chromatogr. 1994, 34, 1-47.
22. Shibukawa, A., Nakagawa, T., Anal. Chem. 1996, 68, 447-454.
23. McDonnell, P. A., Caldwell, G. W., Recent Advances in Analytical Techniques, Gordon and Breach Science Publisher, Amsterdam 1997, in press.
24. Kremer, J. M. H., Wilting, J., Janssen, L. H. M., Pharm. Rev. 1988, 40, 1-47.
25. Kragh-Hansen, U., Pharm. Rev. 1981, 33, 17-53.
26. Jaulmes, A., Vidal-Madjar, C., Adv. Chromatogr. 1989, 28, 1-64.
27. Lemaire, M., Tillement, J. P., Biochem. Pharmacol. 1982, 31, 359-365.
28. Bree, F., Tillement, J.-P., J. Chromatogr. 1986, 375, 416-422.
29. Soltes, L., Bree, F., Sebille, B., Tillement, J.-P., Durisova, M., Trnovec, T., Biochem. Pharmacol. 1985, 34, 4331-4334.
30. Belpaire, F. M., Braeckman, R. A., Bogaert, M. G., Biochem. Pharmacol. 1984, 33, 2065.
31. Kornguth, M. L., Hutchins, L. G., Eichelman, B. S., Biochem. Pharmacol. 1981, 50, 2435-2441.
32. Pike, E., Skuterud, B., Kierulf, P., Bredesen, J. E., Lunde, P. K. M., Clin. Pharmacokin. 1984, 9, 84-85.
33. Pike, E., Skuterud, B., Kierulf, P., Bredesen, J. E., Lunde, P. K. M., Br. J. Clin. Pharmacol. 1983, 16, 233-239.