Structural similarities between hammerhead ribozymes and the spliceosomal RNAs could be responsible for lack of ribozyme cleavage in yeast

Antisense and Nucleic Acid Drug Development

Volumn 8, Issue 1, 1998, Pages 1-13

  Castanotto, Daniela ^a   Li, Haitang ^a   Chow, Warren ^a   Rossi, John J ^a   Deshler, James O ^a,b  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL RNA; RIBOZYME;

ARTICLE; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SPLICEOSOME; TRANSLATION INITIATION;

EID: 0031935854     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1998.8.1     Document Type: Article

References (7)

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2. BASS, B.L., and WEINTRAUB, H. (1988). An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell 55, 1089-1098.
3. BERTRAND, E., PICTET, R., and GRANGE, T. (1994). Can hammerhead ribozyme be efficient tools to inactivate gene function? Nucleic Acids Res. 22, 293-300.
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5. CAMERON, F.H., and JENNINGS, P.A. (1989). Specific gene suppression by engineered ribozymes in monkey cells. Proc. Natl. Acad. Sci. USA 86, 9139-9143.
6. CASABADAN, M.J., and COHEN, S. (1980). In vitro gene fusions that join an enzymatically active β-galactosidase segment to ammo-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational signals. J. Bacteriol. 143, 971-980.
7. ZWEIB, C. (1992). Conformity of RNAs that interact with tetranucleotide loop binding proteins. Nucleic Acids Res. 20, 497-4400.