Immunocytochemical discrimination between early and late S phase: A new approach to the study of gingival epithelium proliferation in rats

Journal of Periodontology

Volumn 69, Issue 1, 1998, Pages 84-91

  Breschi, Lorenzo ^a   Mazzotti, Giovanni ^a   Baratta, Brunella ^a   Galanzi, Angela ^a   Strocchi, Paola ^b   Falconi, Mirella ^c   Centurione, Maria Antonietta ^c   Ferrari, Carlo ^d   Rizzoli, Riccardo ^e,f  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Centro di Farmacologia Respiratoria   (Italy)

^c CNR   (Italy)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e UNIVERSITY OF CHIETI   (Italy)

^f c/o Ist Morfologia Umana Normale ^*  (Italy)

Author keywords

Bromodeoxyuridine therapeutic use; Epithelium; Gingival regeneration; Immunocytochemistry

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA SYNTHESIS; EPITHELIUM CELL; GINGIVA; HETEROCHROMATIN; IMMUNOCYTOTOXICITY; NONHUMAN; RAT; TISSUE DISTRIBUTION; TISSUE REGENERATION;

EID: 0031935771     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.1998.69.1.84     Document Type: Article

References (17)

1. Mazzotti G, Rizzoli R, Galanzi A, et al. High-resolution detection of newly synthesised DNA by anti-bromodeoxyuridine antibodies identifies specific chromatin domains. J Histochem Cytochem 1990; 38:13-22.
2. Rizzoli R, Baratta B, Maraldi NM, et al. DNA synthesis progression in 3T3 synchronised fibroblasts: A high-resolution approach. Histochemistry 1992;97:181-187.
3. Newman GR, Hobot JA. Modem acrylics for post-embedding immunostaining techniques. J Histochem Cytochem 1987;35:971-981.
4. Zini N, Maraldi NM, Martelli AM, et al. Phospholipase C digestion induces the removal of nuclear RNA: A cytochemical quantitative study. Histochem J 1989;21:491-500.
5. Hume WJ, Thompson J. Double labelling of cells with tritiated thymidine and bromodeoxyuridine reveals a circadian rhythm-dependent variation in duration of DNA synthesis and S phase flux rates in rodent oral epithelium. Cell Tissue Kinet 1990;23:313-323.
6. Karring T. Mitotic activity in the oral epithelium. J Periodont Res 1973;13(suppl):11-47.
7. Kellet M, Hume WJ, Potten CS. A topographical study of the circadian rhythm in labelling index of mouse gingival and floor-of-mouth epithelium, including changes in labelling activity with individual cell position on the epithelial ridges. Arch Oral Biol 1989; 34:321-328.
8. Sandhu HS, Tonna EA, Singh LJ. Circadian rhythms of gingival epithelium in young mice. J Periodontol 1987;58:345-348.
9. Brown JM, Berry RJ. The relationship between diurnal variation of the number of cells in mitosis and the number of cells synthesizing DNA in the epithelium of the hamster cheek pouch. Cell Tissue Kinet 1968;1:23-33.
10. Lin LM, Goepp RA, Sewell AE. Diurnal variation of epithelial cell population kinetics of young mouse tongue. J Dent Res 1977;59: 425-436.
11. Zagon IS, Wu Y, McLaughlin PJ. Opioid antagonist modulation of DNA synthesis in mouse tongue epithelium is circadian dependent. Pharmacol Biochem Behav 1994;48:709-714.
12. Christophers E. The columnar structure of the epidermis: Possible mechanism of differentiation. Z Zellforsch mikrosk Anat 1971;114: 441-447.
13. Christophers E. Correlation between column formation, thickness and rate of new cell production in guinea pig epidermis. Virchows Arch Path Anat Physiol, 1972;10:286-292.
14. Allen JD, Potten CS. Fine structural identification and organisation of the epidermal proliferative units. J Cell Sci 1974;15:291-319.
15. Potten CS. The epidermal proliferative unit (EPU). The possible role of the central basal cell. Cell Tissue Kinet 1974;7:77-80.
16. Sengel P. Morphogenesis of Skin. Cambridge, UK: Cambridge University Press; 1976.
17. Hume WJ, Potten CS. Proliferative units in stratified squamous epithelium. Clin Exp Dermatol 1983;8:95-106.