Induction of proliferating cell nuclear antigen and Ki-67 expression by cytomegalovirus infection

Journal of Pathology

Volumn 184, Issue 3, 1998, Pages 279-282

  Mate, José L ^a,c   Ariza, Aurelio ^a   Muñoz, Ana ^a   Molinero, José L ^a   López, Dolores ^b   Navas Palacios, José J ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b Department of Gastroenterology   (Spain)

^c HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Cell cycle; Cytomegalovirus; Ki 67; PCNA

Indexed keywords

AVIDIN; BIOTIN; CYCLINE; KI 67 ANTIGEN; PEROXIDASE; VIRUS ANTIGEN;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; GASTROINTESTINAL BIOPSY; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; PRIORITY JOURNAL; SKIN BIOPSY; VIRUS INCLUSION;

CELL DIVISION; CELL NUCLEUS; CYTOMEGALOVIRUS INFECTIONS; HUMANS; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; PROLIFERATING CELL NUCLEAR ANTIGEN;

EID: 0031935693     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199803)184:3<279::AID-PATH7>3.0.CO;2-4     Document Type: Article

References (18)

1. Jault FM, Jault JM, Ruchti F, et al. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest. J virol 1995; 69: 6697-6704
2. Speir E, Mondali ES, Huang MB, et al. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 1994; 265: 391 -394.
3. Muganda P, Mendoza J, Hernandez J, Quian Q. Human cytomegalovirus elevates levels of the cellular protein p53 in infected fibroblasts. J virol 1994; 68: 8028-8034.
4. Lu M, Shenk T. Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from Gl to S. J Virol 1996 70: 8850-8857.
5. 1/S transition. J Virol 1977; 71: 1629-1634.
6. Shadan FF, Cowsert LM, Villarreal LP. n-Butyrate, a cell cycle blocker, inhibits the replication of polyomavirus and papillomaviruses but not that of adenoviruses and herpesviruses. J Virol 1994; 68: 4785-4796.
7. Hall PA, Levison DA, Woods AL, et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms. J Pathol 1990; 162: 285-294.
8. McCormick D, Chong H, Hobbs C, Datta C, Hall PA. Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1. Histopatholgy 1993; 22: 355-360.
9. Ariza A, Mate JL, Fernández-Vasalo A, et al. p53 and proliferating cell nuclear antigen expression in JC virus-infected cells of progressive multifocal leukoencephalopathy. Hum Pathol 1994; 25: 1341-1345.
10. Penneys NS, Bogaert M, Serfling U, Sisto M. PCNA expression in cutaneous keratinous neoplasms and verruca vulgaris. Am J pathol 1992; 141: 139-142.
11. Boon ME, Howard CV, van Velzen D. PCNA independence of Ki-67 expression in HPV infection. Cell Biol Int 1993; 17: 1001-1004.
12. Demeter LM, Stoler MH, Broker TR, Chow LT. Induction of proliferating cell nuclear antigen in differentiated keratinocytes of human papillomavirus-infected lesions. Hum Pathol 1994; 25: 343-348.
13. Blanton RA, Coltrera MD, Gown AM, Halbert CL, McDougall JK. Expression of the HPV 16 E7 gene generates proliferation in stratified squamous cell cultures which is independent of endogenous p53 levels. Cell Growth Differ 1992; 3: 791-802.
14. Hinchliffe SA, Smith MD, Boon ME, Howard CV, van Velzen D, Rees JL. Evidence for dissociation of histone mRNA expression from cellular proliferation in cutaneous human papillomavirus infection. J Pathol 1996; 178: 249-254.
15. Lehman JM, Laffin J, Jacobberger J, Fogelman D. Analysis of simian virus 40 infection of CV-1 cells by quantitative two-color fluorescence with flow cytometry. Cytometry 1988; 9: 52-59.
16. Ariza A, Mate JL, Serrano S, et al. DNA amplification in glial cells of progressive multifocal leukoencephalopathy: an image analysis study. J Neuropathol Exp Neurol 1996; 55: 729-733.
17. Cross SM, Sánchez CA, Morgan CA, et al. A p53-dependent mouse spindle checkpoint. Science 1995; 267: 1353-1356.
18. Hall PA, McKee PH, Menage HD, Dover R, Lane DP. High levels of p53 protein in UV-irradiated normal human skin. Oncogene 1993; 8: 203-207.