Protective effect of linoleic acid on IFN γ-induced cellular injury in primary culture hepatocytes

Journal of Biochemistry

Volumn 123, Issue 2, 1998, Pages 213-218

  Liang, Jun Feng ^a   Akaike, Toshihiro ^b  

^a TSINGHUA UNIVERSITY   (China)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Cellular injury; Hepatocyte; IFN ; Linoleic acid; Nitric oxide

Indexed keywords

4 BROMOPHENACYL BROMIDE; ARACHIDONIC ACID; CLOFIBRATE; GAMMA INTERFERON; LINOLEIC ACID; LIPOXYGENASE INHIBITOR; LIVER PROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE; NORDIHYDROGUAIARETIC ACID; PEROXISOME PROLIFERATOR; PHOSPHOLIPASE INHIBITOR; POLYUNSATURATED FATTY ACID; PROTEIN;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL RESPIRATION; CONTROLLED STUDY; LIVER CELL CULTURE; LIVER PROTECTION; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; SERUM;

EID: 0031935109     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021924     Document Type: Article

References (38)

1. McClain, C.J. and Cohen, D.A. (1989) Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 9, 349-351
2. Satoh, M. and Yamazaki, M. (1992) Tumor necrosis factor stimulates DNA synthesis of mouse hepatocytes in primary culture and is suppressed by transforming growth factor beta and interleukin 6. J. Cell Physiol. 150, 134-139
3. Tiegs, G., Wolter, M., and Wendel, A. (1989) Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. Biochem. Pharmacol. 38, 627-631
4. Gilles, P.N., Guerrette, D.L., Ulevitch, R.J., Schreiber, R.D., and Chisari, F.V. (1992) HBsAg retention sensitizes the hepatocyte to injury by physiological concentrations of interferon-gamma. Hepatology 16, 655-663
5. Yoshioka, K., Kakumu, S., Arao, M., Tsutsumi, Y., and Inoue, M. (1989) Tumor necrosis factor alpha production by peripheral blood mononuclear cells of patients with chronic liver disease. Hepatology 10, 769-773
6. Ehlers, S., Mielke, M.E.A., Blankenstein, T., and Hahn, H. (1992) Kinetic analysis of cytokine gene expression in the livers of naive and immune mice infected with Listeria monocytogenes. The immediate-early phase in innate resistance and acquired immunity. J. Immunol. 149, 3016-3022
7. Volpes, R., Oord, J.J., Vos, R.D., Depla, E., Ley, M.D., and Desmet, V.J. (1991) Expression of in terferon-gamma receptor in normal and pathological human liver tissue. J. Hepatol. 12, 195-202
8. Morita, M., Watanabe, Y., and Akaike, T. (1995) Protective effect of hepatocyte growth factor on interferon-gamma-induced cytotoxicity in mouse hepatocytes. Hepatology 21, 1585-1693
9. Peters, M., Vierling, J., Gershwin, M.E., Milich, D., Chisari, F.V., and Hoofnagle, J.H. (1991) Immunology and the liver. Hepatology 13, 977-994
10. Koromilas, A.E., Roy, S., Barber, G.N., Katze, M.G., and Sonenbery, N. (1992) Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. Science 257, 1685-1689
11. Harada, H., Kitagawa, M., Tanaka, N., Yamamoto, H., Harada, K., Ishihara, M., and Taniguchi, T. (1993) Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2. Science 259, 971-974
12. Peters, M. (1989) Mechanisms of action of interferons. Semin. Liver Dis. 9, 235-239
13. Bornstein, J., Lahat, N., Kinarty, A., Revel, M., Abramovici, H., and Shapiro, S. (1997) Interferon-beta and -gamma, but not tumor necrosis factor-alpha, demonstrate immunoregulatory effects on carcinoma cell lines infected with human papillomavirus. Cancer 79, 924-934
14. Deiss, L.P. and Kimchi, A. (1991) A genetic tool used to identify thioredoxin as a mediator of a growth inhibitory signal. Science 252, 117-120
15. Deiss, L.P., Feinstein, E., Berissi, H., Cohen, O., and Kimchi, A. (1995) Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 9, 15-30
16. Shimaoka, S., Nakamura, T., and Ichihara, A. (1987) Stimulation of growth of primary cultured adult rat hepatocytes without growth factors by coculture with nonparenchymal liver cells. Exp. Cell. Res. 172, 228-242
17. Gross, S.S. and Levi, R. (1992) Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J. Biol. Chem. 267, 25722-25729
18. Skehan, P. and Friedman, S.J. (1985) A rapid naphthol yellow S method for measuring the cellular protein content of anchorage cultures. In Vitro Cell. Dev. Biol. 21, 288-290
19. Bublitz, C. and Lawler, C.A. (1987) The levels of nicotinamide nucleotides in liver microsomes and their possible significance to the function of hexose phosphate dehydrogenase. Biochem. J. 245, 263-267
20. Flatmark, T., Nilsson, A., Kvannes, J., Eikhom, T.S., Fukami, M.H., Kryvi, H., and Christiansen, E.N. (1988) On the mechanism of induction of the enzyme systems for peroxisomal beta-oxidation of fatty acids in rat liver by diets rich in partially hydrogenated fish oil. Biochim. Biophys. Acta 962, 122-130
21. Zhang, J., Dawson, V.L., Dawson, T.M., and Snyder, S.H. (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263, 687-689
22. Inoue, C., Yamamoto, H., Nakamura, T., Ichihara, A., and Okamoto, H. (1989) Nicotinamide prolongs survival of primary cultured hepatocytes without involving loss of hepatocyte-specific functions. J. Biol. Chem. 264, 4747-4750
23. Ehringer, W., Belcher, D., Wassall, S.R., and Stillwell, W. (1990) A comparison of the effects of linolenic (18:3 omega 3) and docosahexaenoic (22:6 omega 3) acids on phospholipid bilayers. Chem. Phys. Lipids 54, 79-88
24. Muriana, F.J., Vazquez, C.M., and Ruiz-Gutierrez, V. (1992) Fatty acid composition and properties of the liver microsomal membrane of rats fed diets enriched with cholesterol. J. Biochem. 112, 562-567
25. 2+]-increase in differentiated monocytic U937 cells. Biochim. Biophys. Acta 1133, 38-45
26. Swann, P.G., Parent, C.A., and Croset, M. (1990) Enrichment of platelet phospholipids with eicosapentaenoic acid and docosahexaenoic acid inhibits thromboxane A2/prostaglandin H2 receptor binding and function. J. Biol. Chem. 265, 21692-21697
27. Sellmayer, A., Uedelhoven, W.M., Weber, P.C., and Bonventer, J.V. (1991) Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells. J. Biol. Chem. 266, 3800-3807
28. Danesch, U., Weber, P.C., and Sellmayer, A. (1994) Arachidonic acid increases c-fos and Egr-1 mRNA in 3T3 fibroblasts by formation of prostaglandin E2 and activation of protein kinase C. J. Biol. Chem. 269, 27258-27263
29. Kondrup, J. and Lazarow, P.B. (1985) Flux of palmitate through the peroxisomal and mitochondrial beta-oxidation systems in isolated rat hepatocytes. Biochim. Biophys. Acta 835, 147-153
30. Tanaka, K. (1972) On the mode of action of hypoglycin A. 3. Isolation and identification of cis-4-decene-1,10-dioic, cis,cis-4,7-decadiene-1,10-dioic, cis-4-octene-1,8-dioic, glutaric, and adipic acids, N-(methylenecyclopropyl)acetylglycine, and N-isovalerylglycine from urine of hypoglycin A-treated rats. J. Biol. Chem. 247, 7465-7478
31. Mortensen, P.B. and Gregersen, N. (1981) The biological origin of ketotic dicarboxylic aciduria. In vivo and in vitro investigations of the omega-oxidation of C6-C16-monocarboxylic acids in unstarved, starved and diabetic rats. Biochim. Biophys. Acta 666, 394-404
32. Osmundsen, H., Thomassen, M.S., Hiltunen, J.K., and Berge, R.K. (1987) Peroxisome in Biology and Medicine (Fahimi, H.D. and Sies, H., eds.) pp. 152-165, Springer-Verlag, Heidelberg
33. Hiltunen, J.K., Filpulla, S.A., Hayrinen, H.M., Koivuranta, K.T., and Hakkola, E.H. (1993) Peroxisomal beta-oxidation of polyunsaturated fatty acids. Biochimie 75, 175-182
34. + biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet. Biochem. Pharmacol. 52, 247-252
35. Duval, D.L., Sieg, D.J., and Billings, R.E. (1995) Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione. Arch. Biochem. Biophys. 316, 699-706
36. Liang, J.F. and Akaike, T. (1997) Role of metabolic intermediates in lipopolysaccharide/cytokine-mediated production of nitric oxide in isolated mouse hepatocytes. Biochem. Biophys. Res. Commun. 236, 379-382
37. Harbrecht, B.C., Billiar, T.R., Stadler, J., Demetris, A.J., Ochoa, J., Curran, R.D., and Simmons, R.L. (1992) Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury. J. Leukocyte Biol. 52, 390-394
38. Sergent, O., Griffon, B., Morel, I., Chevanne, M., Dubos, M.P., and Cillard, J. (1997) Effect of nitric oxide on iron-mediated oxidative stress in primary rat hepatocyte culture. Hepatology 25, 122-127