In vivo studies on lysosubtilin. 2. Efficacy for treatment of post-partum endometritis in cows

Veterinary Research

Volumn 29, Issue 1, 1998, Pages 47-58

  Biziulevichius, Gediminas Arvydas ^a   Lukauskas, Kazimieras ^b  

^a VILNIUS UNIVERSITY   (Lithuania)

^b State Veterinary Service   (Lithuania)

Author keywords

Calving to conception interval; Cow; Enzymotherapy; Lysosubtilin; Post partum endometritis

Indexed keywords

ANIMALIA; BACILLUS SUBTILIS; FUNGI; NEGIBACTERIA; POSIBACTERIA; BACTERIA (MICROORGANISMS);

ANTIBIOTIC AGENT; LYSOSUBTILIN; NEOFUR; SUBTILIN; UNCLASSIFIED DRUG; UTEROSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACILLUS SUBTILIS; BACTERIAL INFECTION; BELARUS; CONTROLLED STUDY; COW; DRUG EFFECT; DRUG SCREENING; ENDOMETRITIS; FEMALE; GRAM NEGATIVE INFECTION; INTRAUTERINE DRUG ADMINISTRATION; LITHUANIA; MYCOSIS; NONHUMAN; PUERPERIUM; RUSSIAN FEDERATION;

EID: 0031935077     PISSN: 09284249     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (96)

1. Aknazarov B.K., Humoral factors of local protection of uterus in cows, Veterinariya (Moscow) 8 (1988) 41-43 (in Russian, English abstract).
2. Anyulis E., Proteolytic enzymes in treatment of endometritis in cows, LVA mokslo darbai. Veterinariya/Proceedings of the Lithuanian, Academy of Veterinary Medicine, Vet. Med. 19 (1989) 117-122 (in Lithuanian, Russian abstract).
3. Anyulis E., Antimicrobial preparations and proteolytic enzymes in treatment of endometritis in cows, LVA mokslo darbai. Veterinariya/Proceedings of the Lithuanian Academy of Veterinary Medicine, Vet. Med. 20 (1991) 3-7 (in Lihuanian, English and Russian abstrais).
4. Aurich J.E., Grunert E., Pathogenese und Therapie postpuerperaler Endometritiden beim Rind, Collegium. Vet. 26 (1996) 28-30.
5. Bach S., Haase H., Zur Bedeutung genitaler Infektionen beim Rind, Monatshefte fur Veterinärmedizin 44 (1989) 86-89.
6. Barlett P.C., Kirk J.H., Wilke M.A., Kaneene J.B., Mather E.C., Metritis complex in Michigan Holstein-Friesian cattle: incidence, descriptive epidemiology and estimated economic impact, Prev. Vet. Med. 4 (1986) 235-248.
7. Barragry T., Therapy of bovine metritis, Irish. Vet. J 49 (1996) 303-305.
8. Bazhenova N.B., Davydov V.U., Stepanov G.S., Treatment of acute post-partum endometritis in cows. Veterinariya (Moscow) 2 (1989) 42-43 (in Russian, English abstract).
9. Bekana M., Jonsson P., Kindahl H., Intrauterine bacterial findings and hormonal profiles in post-partum cows with normal puerperium, Acta. Vet. Scand. 37 (1996) 251-263.
10. Bezborodin V.V , Niyatbekov A., Yangalichev Ya Kh., Treatment of post-partum endometritis, Veterinariya (Moscow) 6 (1984) 48-49 (in Russian).
11. Biziulevichius G.A., Arestov I.G., In vivo studies on lysosubtiun. 1. Efficacy for prophylaxis and treatment of gastrointestinal disorders in newborn calves. Vet. Res. 28 (1997) 19-35.
12. Biziulevichius G.A., Arestov I.G., Safety of lysosubtilin per os in mice, rabbits, and calves, Vet. Res. 28 (1997) 385-395.
13. Biziulevichius G -A.S., Kislukhina O.V., Lytic enzymes in veterinary medicine. A review, Veterinariya (Moscow) 3 (1988) 56-59 (in Russian).
14. Biziulevichius G.S., Kislukhina O.V., Avizhienis V.J., On the technology of receipt and specificity of action of the preparation lysosubtilin G10X, Trudy VNII prikladnoi enzimologii/Proceedings of the All-Union Research Institute of Applied Enzymology 'Production and application of microbial enzymatic preparations' 3. Mokslas, Vilnius (in Russian, English abstract) (1976) 105-116.
15. Biziulevichius G.-A.S., Shablinskas A.J., Zhukaite V.P., Kislukhina O.V., Lysosubtilin G10X, a new antimicrobial agent for treatment and prophylaxis. Physicochemical properties, Antibiotiki i meditsinskaya biotekhnologiya/Antibiotics and Medical Biotechnology 32 (1987) 331-333 (in Russian, English abstract),
16. Biziulevichius G.-A.S., Shablinskas A.J., Zhukaite V.P , Kislukhina O.V., Antibacterial spectrurh of lysosubtilin G10X, Antibiotiki i khimioterapiya/Antibiotics and Chemotherapy 34 (1989) 579-581 (in Russian, English abstract).
17. Biziulevichius G.A., Zhukaite W., Kislukhina O., Lysosubtilin - a broad-spectrum action preparation of lytic enzymes for veterinary use: in vitro studies on activators and inhibitors, complex structure and antifungal action, Biomed. Lett. 52 (1995) 43-57.
18. Carter G.R., Cole J.R.Jr., Diagnostic Procedures in Veterinary Bacteriology and Mycology (1990), 5th ed, Academic Press, New York.
19. Chaffaux S., Lakhdissi H., Thibier M., Étude épidémioiogique et clinique des endométrites post-puerpérales chez les vaches laitières. Recl. Méd. Vét. Ec Alfort 167 (1991) 349-358.
20. Cohen R.O., Bernstein M., Ziv G., Isolation and antimicrobial susceptibility of A. Pyogenes recovered from the uterus of dairy cows with retained fetal membranes and post parturient endometritis. Theriogenology 43 (1995) 1389-1397.
21. [21 ] Cohen R.O., Colodner R., Ziv G., Keness J., Isolation and antimicrobial susceptibility of obligate anaerobic bacteria recovered from the uteri of dairy cows with retained fetal membranes and post parturient endometritis, J. Vet. Med. B 43 (1996) 193-199.
22. Davies D.A.L., Method for treating fungal infections using cell lytic enzymes, US patent 4062941, 1979
23. Davies D.A.L., Pope A.M.S., Antimicrobial composition comprising lytic enzymes from physarum and an antimycotic agent, US patent 4144327, 1979.
24. De Kruif, Postpartale Endometritis beim Rind, Prakt. Tierarzt. 12 (1994), 1071-1078.
25. Dermidova L.D., Yurkov V.M., Balkovoi I.I., Inozemtsev V.P., Cherkasov A.S., Svirin V.N., Application of laser veterinary apparatus "Vega-MV" for mastitis in cows. Veterinariya (Moscow) 5 (1996) 9-12 (in Russian).
26. Dhaliwal D.S., Murray R.D., Dobson H., Effects of milk yield, and calving to first service interval, in determining herd fertility in dairy cows. Arum. Reprod. Sci. 41 (1996) 109-117.
27. Diskin M.G., Factors affecting conception rate in cows, Irish. Vet. J. 49 (1996) 245-251.
28. Diskin M.G., Regulation of post-partum interval in cattle, Irish Vet. J. 50 (1997) 238-247.
29. 2α and oxytocin on the post partum cow, Am. J. Vet. Res. 45 (1984) 1011-1014.
30. Esslemont R.J., Kossaibati M.A., Culling in 50 dairy herds in England, Vet. Rec. 140 (1997) 36-39.
31. [31 ] Fraser C.M. (ed), The Merck Veterinary Manual. A Handbook of Diagnosis, Therapy and Disease Prevention and Control for the Veterinarian, 7th ed., Merck and Co Inc, Rahway, New Jersey 1991, pp. 692-693.
32. Gavrish V.G., Rodin V.P., Semenov S.V., Hysterofur for therapy of cow endometritis, Veterinariya (Moscow) 5 (1996) 40-43 (in Russian).
33. Gilbert R.O., Bovine endometritis: the burden of proof, Cornell Vet. 82 (1992) 11-13.
34. Gonchar A.M., Semenov B.S., Perspectives of application of preparations of immobilized bacterial proteases, Veterinariya (Moscow) 7 (1988) 57-59 (in Russian).
35. Gonchar A.M., Shelyugina Z.G., Bogdanova L.A., Salganik R.I., Avdeenko V.S., Application of immobilized proteases for treatment of purulent processes, Veterinariya (Moscow) 4 (1989) 52-55 (in Russian, English abstract).
36. Grigorieva T.E., Treatment and Prophylaxis of Endometritis in Cows, Rosseljkhozizdat, Moscow (in Russian) 1988.
37. Grubliauskas L., Znaidauskas B., Antibacterial effect of lytic enzyme preparation lysosubtilin G10X and its influence on activity of antibiotics. Trudy LVA i LNIIV/Proceedings of the Lithuanian Academy of Veterinary Medicine and the Lithuanian Research Institute of Veterinary Medicine 18 (1987) 62-65 (in Russian).
38. Gudimova T.E., Genital diseases and mastitis, Veterinariya (Moscow) 8 (1986) 62 (in Russian).
39. Harman J.L., Gröhn Y.T., Erb H.N., Casella G., Event-time analysis of the effect of 60-day milk production on the parturition-toconception interval in dairy cows. Am. J. Vet. Res. 57 (1996) 634-639.
40. Hussain A.M., Daniel R.C.W., Boyle O., Post-partum uterine flora following normal and abnormal puerperium in cows. Thenogenology 34 (1990) 291-302.
41. Iliynskii Ye V., Troshin A.N., Nazarov M.V., New medicines of plant origin for treatment of uteri, Veterinariya (Moscow) 8 (1996) 56-58 (in Russian, English abstract).
42. Inozemtsev V.P., Balkovoi I I., Sochnev V.V., Samodelkin A.G., UHF electromagnetic Read for endometritis therapy in cows, Veterinariya (Moscow) 11 (1996) 29-31 (in Russian, English abstract).
43. Inozemtsev V.P., Balkovoi I.I., Krylova T.V., Siniaev V.A., Kuklin A.D., Kosorlukova Z. Ya, Miakin N.A., Batrakova Ye A., Nikulin D.M., Pakhomov A.P., Gusev V.A., Doszhanov Yu D., Experience of using laser apparatus STP-3 in veterinary practice, Veterinariya (Moscow) 5 (1997) 32-36 (in Russian).
44. Ivanovskii A.A., New probiotic bactocellolactin for treatment of various pathologies in animals, Veterinariya (Moscow) 11 (1996) 34-35 (in Russian, English abstract).
45. Khiljkevich N.M., Timoshenko O. V., Dzhumaniazov K. Kh., Khiljkevich S.N., Use of anitimicrobial preparations in combination with oxygen for mastitis and some uterus diseases in cows, Veterinariya (Moscow) 3 (1994) 37-39 (in Russian, English abstract).
46. Kislukhina O. V., Determination of lytic activity of lysosubtilin by action towards Escherichia coli cells, Mikrobiologicheskaya promyshlennostj/Mikrobiological industry 141 (1976) 43-45 (in Russian).
47. Kondrakhin I.P., Perspectives of application of enzymes in veterinary practice, Veterinariya (Moscow) 8 (1990) 61-64 (in Russian, English abstract).
48. Kremlev E.P., Prophylaxis of infertility in cows, Veterinariya (Moscow) 3 (1982) 46-48 (in Russian).
49. Kremlev E.P., Banakova L.A., Tkachenko Yu G., Iodine containing preparations for therapy of endometritis, Veterinariya (Moscow) 1 (1985) 49-51 (in Russian).
50. Kuklin A.D., Kosorlukova Z. Ya, Treatment of cows with endometritis, Veterinariya (Moscow) 1 (1987) 47-48 (in Russian).
51. Lacombe J.-F.P.L., Nouveau médicament vétérinaire destiné au traitment des mammites infectieuses des bovins et des caprins à base de polymixine, d'éritromycine et de lysozyme, French patent 2528703, 1983.
52. Mac Gregor R.G., Evaluation of calving date and calving interval as measures of reproductive efficiency in beef cows, J. S. Afr. Vet. Assoc. 66 (1995) 235-238.
53. Malashenko N.P., Furazolidone sticks 'Ultra' for treatment of inflammatory processes in uterus, Veterinariya (Moscow) 3 (1997) 44-45 (in Russian, English abstract).
54. Markusfeld O., Factors responsible for post-parturient metritis in dairy cattle. Vet. Rec. 114 (1984) 539-542.
55. Marushka R., Treatment of cow uterus with enzyme and antimicrobial preparations, LVA mokslo darbai. Veterinariya/Proceedings of the Lithuanian Academy of Veterinary Medicine. Vet. Med. 19 (1989) 153-156 (in Lithuanian, Russian abstract).
56. Miroliubov M.G., Borskov A.A., Vagina and uterus diseases in cows, Veterinariya (Moscow) 7 (1984) 51-52 (in Russian).
57. Money I.A.L., Efficacy of pefloxacin treatment for endometritis in cow, Indian Vet. J. 73 (1996) 1072-1073.
58. Murtazin B.F., Pulatov G.S., On etiology of endometritis in cows, Veterinariya (Moscow) 4 (1995) 41-44 (in Russian, English abstract).
59. Nakao T., Moriyoshi M., Kawata K., Effect of post-partum intrauterine treatment with 2 percent polyvinylpyrrolidone-todine solution on reproductive efficiency in cows, Theriogenology 30 (1988) 1033-1043
60. Nezhdanov A.G., Koniaev M.T., Treatment of cows with endometritis and subinvolution of the uterus, Veterinariya (Moscow) 1 (1982) 45-46 (in Russian).
61. Nikolaevskii I.I., Lysozyme in treatment of gynaecological diseases of agricultural animals, Doct Diss Vet Sci., Moscow Veterinary Academy, Moscow (in Russian).
62. Noakes D.E., Till D., Smith R.G., Bovine uterine flora post partum: a comparison of swabbing and biopsy. Vet. Rec. 124 (1989) 563-564.
63. Opekunov K.A., Ivanovskii A.A., Vepreva N.S., Dry biosan for treatment of endometritis in cows, Veterinariya (Moscow) 2 (1994) 39-40 (in Russian, English abstract).
64. On R.S., Gustafsson R.K., Use of prostaglandins for the treatment of bovine pyometra and post-partum infections, A review. Compendium on Continuing Education for the Practicing Veterinarian 3 (1981) 184-188.
65. Plakhotin M.V., Gafurov D.S., Filippov Yu I., Enzymotherapy of purulent-necrotic processes, Veterinariya (Moscow) 11 (1985), 58-59 (in Russian).
66. Prescott J.F., Baggot J.D., Antimicrobial Therapy in Veterinary Medicine, 2nd ed., Iowa State University Press, Ames, Iowa, 1993
67. Proctor V.A., Cunningham F.E., The chemistry of lysozyme and its use as a food preservative and a pharmaceutical, Crit. Rev. Food. Sci. Nutr. 26 (1988) 359-395.
68. Rabochev V.K., Rodina A.I., Serov V.M., Volkov V.I., Alimbekov M., Akbaev A., Getas for therapy of genital organ diseases, Veterinariya (Moscow) 3 (1983) 50-51 (in Russian).
69. Reynolds J.E.F. (ed), Martindale the Extra Pharmacopoeia, 28th ed., Pharmaceutical Press, London, 1982, pp. 651-652.
70. Rokitskii P.F., Biological Statistics Vysheisha shkola , Minsk (in Russian) 1973.
71. Rubanets L.N., Desoxyfur for therapy of postpartum endometritis, Veterinanya (Moscow) 6 (1986) 51-53 (in Russian).
72. Sava G., Pharmacological aspects and therapeutic applications of lysozymes, in: Jolles P. (Ed.), Lysozymes: Model Enzymes in Biochemistry and Biology, Birkhauser Verlag, Basel, 1996, pp. 433-449.
73. Selivanova A.S., Morozov A.P., Kovalev V.F., Avsjukevich V.S., Antibiotics for practice, Veterinariya (Moscow) 4 (1984) 53-56 (in Russian).
74. Shatalov V.F., Nekhaev E.E., Khrapkovskaya L.P., Susceptibility of bacteria from genital organs of animals to preparations, Veterinariya (Moscow) 9 (1985) 46-47 (in Russian).
75. Shelyugina Z.G., Avdeenko V.S., Gonchar A.M., Salganik RJ., Pankov B.C., Goncharov V.P., Stradina Yu N., Immobilized proceolytic enzymes for post-partum purulent-catarrhal endometritis in cows, Veterinariya (Moscow) 6 (1989) 41-42 (in Russian, English abstract).
76. Sherenas A.J., Struggle Against Infertility in Cows, Komi Knizhnoe Izdateljstvo, Syktyvkar (in Russian) 1984.
77. Sherenas A.J., Treatment and Prophylaxis of Gynaecological Diseases in Cows, Komi Knizhnoe Izdateljstvo, Syktyvkar (in Russian) 1989.
78. Slimane N., Ahmadi C., Ouali F., Kachti M., Thibier M., Analyses épidémiologique et clinique des endométrites post-puerpérales chez les bovins laitiers en Tunisie, Recl. Méd. Vét. Ec Alfort 170 (1994) 823-832.
79. Slipchenko S.N., Timchenko L.D., Lactobril for therapy of acute purulent-catarrhal endometritis in cows. Veterinariya (Moscow) 11 (1994) 34-36 (in Russian).
80. Studentsov A.P., Shipilov V.S., Subbotina L.G., Preobrazhenskii O.N., Veterinary Obstetrics and Gynaecology, 6th ed., Agropromizdat, Moscow (in Russian) 1986.
81. Sundlof S.F., Kaneene J.B., Miller R.A., National survey on veterinarian-initiated drug use in lactatins dairy cows, J. Am. Vet. Med. Assoc. 207 (1995) 347-352.
82. Sutka P., Candida guillermondii var-guillermondii infection in cows slaughtered because of infertility and udder inflammation, Acta. Vet. (Belgrade) 5-6 (1983) 287-289.
83. Tainturier D., Fieni F., Bruyas J.F., Beloeil V., Lyoen A., Candidose et troubles de la reproduction chez la vache. 1. Premiers essais d'un traitement de desensibilisation en fin de gestalion, Rev. Méd. Vét. (Toulouse) 144 (1993) 411-414.
84. Tainturier D., Chatagnon G., Fieni F., Bruyas J.F., Batut I., Candidose et troubles de la reproduction chez la vache: enquête sérologique. Rev. Méd. Vét. (Toulouse) 146 (1995) 35-40.
85. Tainturier D., Fieni F., Bruyas J.F., Batut I., Candidose et troubles de la reproduction chez la vache. 3. Essais d'un traitement de désensibilisation chez les vaches infécondes à chaleurs régulières, Rev. Méd. Vét. (Toulouse) 146 (1995) 497-500.
86. Thurmond M.C., Jameson C.M., Picanso J.P., Effect of intrauterine antimicrobial treatment in reducing calving-to-conception interval in cows with endometritis, J. Ann. Vet. Med. Assoc. 203 (1993) 1576-1578,
87. Trishkina E.T., Galushko L. Kh., Microbial factor in etiology of post-partum endometritis in cows, Veterinariya (Moscow) 11 (1985) 52-53 (in Russian).
88. Vallet A., Carteau M., Salmon A., Chatelin Y., Épidémiologie des endométrites des vaches laitières. Recl. Méd. Vét. Ec Alfort 163 (1987) 189-194.
89. Veremei E.I., Magnetotherapy in clinical veterinary medicine, Veterinariya (Moscow) 5 (1996) 45-48 (in Russian, English abstract).
90. Voskoboinik V.F., Treatment of post-partum endometritis in cows, Veterinariya (Moscow) 5 (1987) 54-56 (in Russian).
91. Yarushin A.D., Prophylaxis of reproduction organ diseases in cows, Veterinariya (Moscow) 3 (1992) 41-43 (in Russian, English abstract).
92. Youngquist R.S., Fertility and Infertility in Veterinary Practice, Baliere Tindail, London, 1988.
93. Znaidauskas B., Marushka R., Malakauskas V., Laurusevichius S., Toxicity assessment of enzyme preparation lysosubtilin G10X, LVA mokslo darbai. Veterinariya/Proceedings of the Lithuanian Academy of Veterinary Medicine, Vet. Med. 19 (1989) 184-187 (in Lithuanian, Russian abstract).
94. Znaidauskas B., Marushka R., Biziulevichius G., Laurusevichius S., Application of enzyme preparation lysosubtilin G10X for treatment of endometrilis in cows, LVA ir LVI mokslo darbai. Veterinariya/Proceedings of the Lithuanian Academy of Veterinary Medicine and the Lithuanian Institute of Veterinary Medicine, Vet. Med. 21 (1994) 85-88 (in Lithuanian, English and Russian abstracts).
95. Zyubin I N., Bovine Metritis, Agropromizdat, Moscow (in Russian) 1988.
96. Zyubin I.N., Zyubina M.F., Microflora of genitals in cows, Veterinariya (Moscow) 9 (1982) 50-52 (in Russian).