Expression of CD54 (intercellular adhesion molecule-1) and the β1 integrin CD29 is modulated by a cyclic AMP dependent pathway in activated primary rat microglial cell cultures

Inflammation

Volumn 22, Issue 1, 1998, Pages 95-106

  Zuckerman, Steven H ^a   Gustin, Jason ^b   Evans, Glenn F ^a  

^a ELI LILLY AND COMPANY   (United States)

^b DEPAUW UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CD11B ANTIGEN; CYCLIC AMP; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; ISOBUTYLMETHYLXANTHINE; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; FLOW CYTOMETRY; MICROGLIA; NERVE CELL CULTURE; NONHUMAN; RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; ANTIGENS, CD29; CELLS, CULTURED; CYCLIC AMP; FETUS; FLOW CYTOMETRY; FORSKOLIN; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MICROGLIA; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0031933761     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022351908951     Document Type: Article

References (32)

1. KREUTZBERG, G. W. 1996. Microglia: A sensor for pathological events in the CNS. Trends Neurosci. 19:312.
2. MOORE, S. and S. THANOS. 1996. The concept of microglia in relation to central nervous system disease and regeneration. Progr. Neurobiol. 48:441.
3. ZIELASEK, J. and H.-P. HARTUNG. 1996. Molecular mechanisms of microglial activation. Adv. Neuroimmunol. 6:191.
4. FREI, K., H. LINS, C. SCHWERDEL, and A. FONTANA. 1994. Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed. J. Immunol. 152:2720.
5. FREI, K., C. SIEPL, P. GROSCURTH, S. BODMER, C. SCHWERDEL, and A. FONTANA. 1987. Antigen presentation and tumor cytotoxicity by interferon-γ-treated microglial cells. Eur. J. Immunol. 17:1271.
6. SMYTH, S. S., C. C. JONECKIS, and L. V. PARISE. 1993. Regulation of vascular integrins. Blood 81:2827.
7. PRIETO, J., A. EKLUND, and M. PATARROYO. 1994. Regulated expression of integrins and other adhesion molecules during differentiation of monocytes into macrophages. Cell Immunol. 156:191.
8. LAFRENIE, R. M. and K. M. YAMADA. 1996. Integrin-dependent signal transduction. J. Cell Biochem. 61:543.
9. HEMLER, M. E. 1990. VLA proteins in the integrin family: Structures, functions and their role on leukocytes. Ann. Rev. Immunol. 8:365.
10. LAVENS, S. E., K. GOLDRING, L. H. THOMAS, and J. A. WARNER. 1996. Effects of integrin clustering on human lung mast cells and basophils. Am. J. Respir. Cell Mol. Biol. 14:95.
11. FAULL, R. J. and M. H. GINSBERG. 1995. Dynamic regulation of integrins. Stem Cells 13:38.
12. STEWART, M. and N. HOGG. 1996. Regulation of leukocyte integrin function: Affinity vs. avidity. J. Cell Biochem. 61:554.
13. CLARK, W. M., J. D. LAUTEN, N. LESSOV, W. WOODWARD, and B. M. COULL. 1995. Time course of ICAM-1 expression and leukocyte subset infiltration in rat forebrain ischemia. Molec. and Chemical Neuropathol. 26:213.
14. SOBEL, R., M. MITCHELL, and G. FINDREN. 1990. Intercellular adhesion molecule-1 (ICAM) in cellular immune reactions in the human central nervous system. Am. J. Pathol. 136:1309.
15. WILCOX, C., A. WARD, A. EVANS, D. BAKER, R. ROTHELEIN, and J. TURK. 1990. Endothelial cell expression of the intercellular adhesion molecule-1 (ICAM-1) in the central nervous system of guinea pigs during acute and chronic relapsing experimental allergic encephalomyelitis. J. Neumimmunol. 30:43.
16. BENVENISTE, E. N., B. S. HUNEYCUTT, P. SHRIKANT, and M. E. BALLESTAS. 1995. Second messenger systems in the regulation of cytokines and adhesion molecules in the central nervous system. Brain Behavior and Immunity 9:304.
17. SHRIKANT, P., E. WEBER, T. JILLING, and E. N. BENVENISTE. 1995. Intercellular adhesion molecule-1 gene expression by glial cells. J. Immunol. 155:1489.
18. SHRIKANT, P., D. J. BENOS, L. P. TANG, and E. N. BENVENISTE. 1996. HIV glycoprotein 120 enhances intercellular adhesion molecule-1 gene expression in glial cells. Involvement of Janus kinase signal transducer and activator of transcription and protein kinase C signaling pathways. J. Immunol. 156:1307.
19. SHRIKANT, P., S. J. LEE, I. KALVAKOLANU, R. M. RANSOHOFF, and E. N. BENVENISTE. 1996. Stimulus-specific inhibition of intracellular adhesion molecule-1 gene expression by TGF-beta. J. Immunol. 157:892.
20. TOMOZAWA, Y., T. INOUE, M. TAKAHASHI, M. ADACHI, and M. SATOH. 1996. Apoptosis of cultured microglia by the deprivation of macrophage colony-stimulating factor. Neuroscience Res. 25:7.
21. DING, A. H., C. F. NATHAN, and D. J. STUEHER. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. J. Immunol. 141:2407.
22. DEL RIO-HORTEGA, P. 1932. Microglia. In Cytology and Cellular Pathology of the Nervous System. Vol. II. W. Penfield, editor. Paul B. Hoeber, New York. p. 481.
23. BARRON, K. D. 1995. The microglial cell. A historical review. J. Neurol. Sci. 134:57.
24. VINCENT, V. A. M., F. J. H. TILDERS, and A.-M. VAN DAM. 1997, Inhibition of endotoxin-induced nitric oxide synthase production in microglial cells by the presence of astroglial cells: A role for transforming growth factor β. Glia 19:190.
25. LODGE, P. A. and S. SRIRAM. 1996. Regulation of microglial activation by TGF-β, IL-I0, and CSF-1. J. Leuk. Biol. 60:502.
26. MONTERO-MENEI, C. N., L. SINDJI, E. GARCION, M. MEGE, D. COUEZ, E. GAMELIN, and F. DARCY. 1996. Early events of the inflammatory reaction induced in rat brain by lipopolysaccharide intracerebral injection: relative contribution of peripheral monocytes and activated microglia. Brain Res. 724:55.
27. KATO, H., K. KOGURE, X. H. LIU, T. ARAKI, and Y. ITOYAMA. 1996. Progressive expression of immunomolecules on activated microglia and invading leukocytes following focal cerebral ischemia in the rat. Brain Res. 734:203.
28. 2 and cyclic AMP-elevating agents. J. Neuroimmunol. 72:83.
29. HELLENDALL, R. P., and J. P. Y. TING. 1997. Differential regulation of cytokine-induced major histocompatibility complex class II expression and nitric oxide release in rat microglia. J. Neuroimmunol. 74:19.
30. BOUILLON, M., M. A. FORTIER, R. BOULIANNE, and M. AUDETTE. 1992. Biphasic effect of cAMP-elevating agents on ICAM-1 expression stimulated by retinoic acid and interferon gamma. Internatl. J. Cancer 50:281.
31. POBER, J. S., M. R. SLOWIK, L. G. DE LUCA, and A. J. RITCHIE. 1993. Elevated cyclic AMP inhibits endothelial cell synthesis and expression of TNF-induced endothelial leukocyte adhesion molecule-1, and vascular cell adhesion molecule-1, but not intercellular adhesion molecule-1. J. Immunol 150:5114.
32. OCHI, H., N. KUME, E. NlSHI, and T. KITA. 1995. Elevated levels of cAMP inhibit protein kinase C-independent mechanisms of endothelial platelet-derived growth factor-B chain and intercellular adhesion molecule-1 gene induction by lysophosphatidylcholine. Circ. Res. 77:530.