Multiple organ involvement during experimental cytomegalovirus infection is associated with disseminated vascular pathology

Journal of Pathology

Volumn 184, Issue 1, 1998, Pages 103-109

  Persoons, Maike C J ^a   Stals, Frans S ^a   Van Dam Mieras, Maria C E ^a   Bruggeman, Cathrien A ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cytomegalovirus; Diffuse intravascular coagulation; Endothelium; Multiple organ disease; Vasculitis

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; DISSEMINATED INTRAVASCULAR CLOTTING; ENDOTHELIUM INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM;

ANIMALS; CYTOMEGALOVIRUS INFECTIONS; DISEASE MODELS, ANIMAL; DISSEMINATED INTRAVASCULAR COAGULATION; ENDOTHELIUM, VASCULAR; HEMORRHAGE; IMMUNOENZYME TECHNIQUES; MALE; RATS; RATS, INBRED WKY; SKIN; STOMACH ULCER; VASCULITIS;

EID: 0031933692     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199801)184:1<103::AID-PATH964>3.0.CO;2-C     Document Type: Article

References (35)

1. Minick CR, Dreesman GR, McCollum CH, Petrie BL, Burek J, De Bakey ME. Cytomegalovirus antigen within human arterial smooth muscle cells. Lancet 1983; 2: 644-647.
2. Yamashiroya HM, Ghosh L, Yang R, Robertson AL. Herpesviridae in the coronary arteries and aorta of young trauma victims. Am J Pathol 1988; 130: 71-79.
3. Hendrix MGR, Daemen MJAP, Bruggeman CA. Cytomegalovirus nucleic acids distribution within the human vascular tree. Am J Pathol 1991; 138: 563-567.
4. Persoons MCJ, Daemen MJAP, Bruning JH, Bruggeman CA. Active cytomegalovirus infection of arterial smooth muscle cells in immunocompromised rats. A clue to herpesvirus-associated atherogenesis? Circ Res 1994; 75: 214-220.
5. Grattan MT, Moreno-Cabral CE, Starnes VA, Oyer PE, Stinson EB, Shumway NE. Cytomegalovirus infection is associated with cardiac allograft rejection and atherosclerosis. J Am Med Assoc 1989; 261: 3561-3566.
6. Bruning JH, Persoons MCJ, Lemstrom KB, Stals FS, De Clereq E, Bruggeman CA. Enhancement of transplantation associated atherosclerosis by CMV, which can be prevented by antiviral therapy in the form of HPMPC. Transplant Int 1994; 7 (Suppl 1): 365-370.
7. Koskinen P, Lemström K, Bruggeman C, Lautenschlager I. Häry P. Acute cytomegalovirus infection induces a subendothelial inflammation (endothelialitis) in the allograft vascular wall. A possible linkage with enhanced allograft arteriosclerosis. Am J Pathol 1994; 144: 41-50.
8. Foucar E, Mukai K, Foucar K, Sutherland DER, Van Buren CT. Colon ulceration in lethal cytomegalovirus infection. Am J Clin Pathol 1981; 76: 788-801.
9. Francis ND, Boylston AW, Roberts AHG, Parkin JM, Pinching AJ. Cytomegalovirus infection in gastrointestinal tracts of patients with HIV-1 or AIDS. J Clin Pathol 1989; 42: 1055-1064.
10. Wilcox CM, Diehl DL, Cello JP, Margaretten W, Jacobson MA. Cytomegalovirus esophagitis in patients with AIDS. A clinical, endoscopic, and pathologic correlation. Ann Intern Med 1990; 113: 589-593.
11. Lin CS, Penha PD, Krishnan MN, Zak FG. Cytomegalic inclusion disease of the skin. Arch Dermatol 1981; 117: 282-284.
12. Lee JYY. Cytomegalovirus infection involving the skin in immunocompromised hosts. A clinicopathologic study. Am J Pathol 1989; 92: 96-100.
13. Percivalle E, Revello MG, Vago L, Morini F, Gerna G. Circulating endothelial giant cells permissive for human cytomegalovirus (HCMV) are detected in disseminated HCMV infections with organ involvement. J Clin Invest 1993; 92: 663-670.
14. Grefte JMM, van der Giessen M, van Son WJ, The TH. Circulating human cytomegalovirus (HCMV)-infected endothelial cells in patients with an active HCMV infection. J Infect Dis 1993; 167: 270-277.
15. Alford CA, Stagno S, Pass RF, Britt WJ. Congenital and perinatal cytomegalovirus infections. Rev Infect Dis 1990; 12 (Suppl 7): S745-S753.
16. Bruggeman CA, Meijer H, Bosman F, van Boven CPA. Biology of rat cytomegalovirus infection. Intervirology 1985; 24: 1-9.
17. Stals FS, Bosman F, van Boven CPA, Bruggeman CA. An animal model for therapeutic intervention studies of CMV infection in the immunocompromised host. Arch Virol 1990; 114: 91-108.
18. Bruning JH, Debie WHM, Dormans PHJ, Meijer H, Bruggeman CA. The development and characterization of monoclonal antibodies against rat cytomegalovirus induced antigens. Arch Virol 1987; 94: 55-70.
19. Van Dam-Mieras MCE, Muller AD, van Dieyen G, Hemker HC. Blood coagulation Factors II, V, VII, IX, and XI. Determination by clotting assays. In: Methods of Enzymatic Analysis. Vol. V. Weinheim: Verlag Chemie, 1984.
20. Span AHM, Frederik PM, Grauls G, van Boven CPA, Bruggeman CA. CMV induced vascular injury: an electron microscopic study in the rat. In vivo 1993; 7: 567-574.
21. Span AHM, Endert J, van Boven CPA, Bruggeman CA. Virus induced adherence of monocytes to endothelial cells. FEMS Microbiol Immunol 1989; 47: 237-244.
22. Span AHM, van Dam-Mieras MCE, Muller W, Endert J, Muller AD, Bruggeman CA. The effect of virus infection on the adherence of leucocytes or platelets to endothelial cells. Eur J Clin Invest 1991; 21: 721-731.
23. 2+ responses in cytomegalovirus infected fibroblasts of human origin. Virology 1987; 157: 259-267.
24. Van Dam-Mieras MCE, Bruggeman CA, Muller AD, Debie WHM, Zwaal RFA. Induction of endothelial cell procoagulant activity by cytomegalovirus infection. Thromb Res 1987; 47: 69-75.
25. Dankner WM, McCutchan JM, Richman DD, Hirata K, Spector SA. Localization of human cytomegalovirus in peripheral blood leucocytes by in situ hybridization. J Infect Dis 1990; 161: 31-36.
26. Salzman RL, Quirk MR, Jordan MC. High levels of circulating cytomegalovirus DNA reflect visceral organ disease in viremic immunosuppressed patients other than marrow recipients. J Clin Invest 1992; 90: 1832-1838.
27. Waldman WJ, Knight DA, Huang EH, Sedmak DD. Bidirectional transmission of infectious cytomegalovirus between monocytes and vascular endothelial cells: an in vitro model. J Infect Dis 1995; 171: 263-272.
28. Scholz M, Cinatl J, Gross V, et al. Impact of oxidative stress on human cytomegalovirus replication and on cytokine-mediated stimulation of endothelial cells. Transplantation 1996; 61: 1763-1770.
29. Vossen RcRM, Persoons MCJ, Slobbe van Drunen MEP, Bruggeman CA, van Dam Mieras MCE. Intracellular thiol redox status affects cytomegalovirus infection of vascular cells. Virus Res 1997; 46: 65-74.
30. Golden MP, Hammer SM, Wanke CA, Albrecht MA. Cytomegalovirus vasculitis. Case reports and reviews of the literature. Medicine 1994; 73: 246-255.
31. Muldoon J, O'Riordan K, Rao S, Abecassis M. Ischaemic colitis secondary to venous thrombosis. A rare presentation of cytomegalovirus vasculitis following renal transplantation. Transplantation 1996; 61: 1651-1653.
32. Morgello S, Cho E-S, Nielsen S, Devinsky O, Petito CK. Cytomegalovirus encephalitis in patients with the acquired immunodeficiency syndrome: an autopsy study of 30 cases and a review of the literature. Hum Pathol 1987; 18: 289-297.
33. Van Dam-Mieras MCE, Muller AD, Van Hinsbergh VWM, Mullers WJHA, Bomans PHH, Bruggeman CA. The procoagulant response of cytomegalovirus infected endothelial cells. Thromb Haemostasis 1992; 68: 364-370.
34. Woodroffe SB, Garnett HM, Danis VA, Interleukin-1 production and cell activation response to cytomegalovirus infection of vascular cells. Arch virol 1993; 133: 295-308.
35. Bevilacqua MP, Pober JS, Majeau GR, Fiers W, Cotran RS, Gimbrone JR. Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc Natl Acad Sci USA 1986; 83: 4533-4537.