Apa I polymorphism in the vitamin D receptor gene may affect the parathyroid response in Japanese with end-stage renal disease

Kidney International

Volumn 53, Issue 2, 1998, Pages 454-458

  Yokoyama, Keitaro ^a   Shigematsu, Takashi ^b   Tsukada, Toshihiko ^b   Ogura, Yousuke ^b   Takemoto, Fumi ^b   Hara, Sigeko ^b   Yamada, Akira ^b   Kawaguchi, Yoshindo ^b   Hosoya, Tatsuo ^b  

^a TORANOMON HOSPITAL   (Japan)

^b NONE

Author keywords

End stage renal disease; Gene polymorphism; Intact osteocalcin; Secondary hyperparathyroidism; Vitamin D receptor

Indexed keywords

OSTEOCALCIN; PARATHYROID HORMONE; RESTRICTION ENDONUCLEASE; VITAMIN D RECEPTOR;

ADULT; ARTICLE; FEMALE; GENE FREQUENCY; HUMAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; PARATHYROID HORMONE BLOOD LEVEL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SECONDARY HYPERPARATHYROIDISM; UREMIA;

EID: 0031933280     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00781.x     Document Type: Article

References (39)

1. DELMEZ JA, SLATOPOLSKY E: Recent advances in the pathogenesis and therapy of uremic secondary hyperparathyroidism. J Clin Endocrinol Metab 72:735-739, 1991
2. SLATOPOLSKY E, WEERTS C, THIELAN J, HORST R, HARTER H, MARTIN KJ: Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25 dihydroxy cholecalciferol in uremic patients. J Clin Invest 74:2136-2143, 1984
3. PORTALE PA, BOOTH BE, HALLORAN BP, MORRIS RC JR: Effect of dietary phosphorus on circulating concentrations of 1,25 dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency. J Clin Invest 73:1580-1589, 1994
4. 3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients. J Clin Invest 92:1436-1443, 1993
5. REICHEL H, KOEFFLER HP, NORMAN AW: The role of the vitamin D endocrine system in health and disease. N Engl J Med 320:980-991, 1989
6. NORMAN AW: Intestinal calcium absorption: A vitamin D hormone-mediated adaptive response. Am J Clin Nutr 51:290-300, 1990
7. 3, and radiology in end-stage renal disease. Kidney Int 44:1071-1077, 1993
8. CHARHON SA, DELMAS PD, MALAVAL L, CHAVASSIEUX PM, ARLOT M, CHAPUY MC, MEUNIER PJ: Serum bone Gla-protein in renal osteodystrophy: Comparison with bone histomorphometry. J Clin Endocrinol Metab 63:892-897, 1986
9. TOKITA A, KELLY PJ, NGUYEN TV, QI JC, MORRISON NA, RISTELI L, RISTELI J, SAMBROOK PN, EISMAN JA: Genetic influences on type I collagen synthesis and degradation: Further evidence for genetic regulation of bone turnover. J Clin Endocrinol Metab 78:1461-1466, 1994
10. MORRISON NA, QI JC, TOKITA A, KELLY PJ, CROFTS L, NGUYEN TV, SAMBROOK PN, EISMAN JA: Prediction of bone density from vitamin D receptor alleles. Nature 367:284-287, 1994
11. HUSTMYER FG, PEACOCK M, HUI S, JOHNSTON CC, CHRISTIAN J: Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus. J Clin Invest 94:2130-2134, 1994
12. RIGGS BL, NGUYEN TV, MELTON LJ 3RD, MORRISON NA, O'FALLON WM, KELLY PJ, EGAN KS, SAMBROOK PN, MUHS JM, EISMAN JA: The contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women. J Bone Miner Res 10:991-996, 1995
13. KRALL EA, PARRY P, LICHTER JB, DAWSON-HUGHES B: Vitamin D receptor alleles and rates of bone loss: Influences of years since menopause and calcium intake. J Bone Miner Res 10:978-984, 1995
14. TOKITA A, MATSUMOTO H, MORRISON NA, TAWA T, MIURA Y, FUKAMAUCHI K, MITSUHASHI N, KUWABARA M, YAMAMORI S, MIURA M, WATANABE T, KUWABARA Y, YABUTA K, EISMAN JA: Vitamin D receptor alleles, bone mineral density and turnover in premenopausal Japanese women. J Bone Miner Res 11:1003-1009, 1996
15. OWADA M, SUZUKI K, HONDA T, YAMADA H, TSUKIKAWA S, HOSHI K, SATO A: Effect of vitamin D receptor gene polymorphism on vitamin D therapy for post menopausal bone loss. (Japanese) Acta Obstetr Gynaecol Jpn 48:799-805, 1996
16. PAYNE RB, LITTLE AJ, WILLIAMS RB, MILNER JR: Interpretation of serum calcium in patients with abnormal serum proteins. Br Med J 4:643-646, 1973
17. 3. J Biol Chem 263:2203-2208, 1988
18. SILVER J, NAVEH-MANY T, MAYER H, SCHMELZER HJ, POPOVTZER MM: Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rats. J Clin Invest 78:1296-1306, 1988
19. LEE EJ, KIM KR, LEE HC, HUH KB: Lack of association between vitamin D receptor genotypes and osteoporosis in Koreans. J Clin Endocrinol Metab 80:3677-3681, 1995
20. TSUKAMOTO T, HEISHI M, NAGABA Y, KOBAYASHI N, NOMURA Y, TAKAHASHI K, TAZAWA H: More on hyperparathyroidism and the vitamin D receptor. Nature Med 1:1309, 1995
21. EBIHARA K, MASUHIRO Y, KITAMOTO T, SUZAWA M, UEMATSU Y, YOSHIZAWA T, ONO T, HARADA H, MATSUDA K, HASAGAWA T, MASUSHIGE S, KATO S: Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathway. Mol Cell Biol 16:3393-3400, 1996
22. HAWA NS, COCKERILL FJ, VADHER S, HEWISON M, RUT AR, PIKE JW, O'RIORDAN JLH, FARROW SM: Identification of a novel mutation in hereditary vitamin D resistant rickets causing exon skipping. Clin Endocrinol 45:85-92, 1996
23. CARLING T, RIDEFELT P, HELLMAN P, RASTAD J, AKERSTROM G: Vitamin D receptor polymorphisms correlate to parathyroid cell function in primary hyperparathyroidism. J Clin Endocrinol Metab 82:1772-1775, 1997
24. BROWN AJ, ZHONG M, FINCH J, RITTER C, MCCRACKEN R, MORRISSEY J, SLATOPOLSKY E: Rat calcium sensing receptor is regulated by vitamin D but not by calcium. Am J Physiol 270:F454-F460, 1996
25. DELMEZ JA, TINDIRA C, GROOMS P, DUSSO A, WINDUS DW, SLATOPOLSKY E: Parathyroid hormone suppression by intravenous 1,25 dihydroxyvitamin D: A role for increased sensitivity to calcium. J Clin Invest 83:1349-1355, 1989
26. MOCHARLA H, BUTCH AW, PAPPAS AA, FLICK JT, WEISTEIN RS, TOGNI PD, JILKA RL, ROBERSON PK, PARFITT AM, MANOLAGAS SC: Quantification of vitamin D receptor mRNA by competitive polymerase chain reaction in PBMC: Lack of correspondence with common allelic variants. J Bone Miner Res 12:726-733, 1997
27. MATSUYAMA T, ISHII S, TOKITA A, YABUTA K, YAMAMORI S, MORRISON NA, EISMAN JA: Vitamin D receptor genotypes and bone mineral density. Lancet 345:1238-1239, 1995
28. HOWARD G, NGUYEN T, MORRISON N, WATANABE T, SAMBROOK P, EISMAN J, KELLY PJ: Genetic influences on bone density: Physiological correlates of vitamin D receptor gene alleles in premenopausal women. J Clin Endocrinol Metab 80:2800-2805, 1995
29. SLATOPOLSKY E, FINCH J, DENDA M, RITTER C, ZHONG M, DUSSO A, MACDONALD PN: Phosphorus restriction prevents parathyroid growth. High phosphorus directly stimulates PTH secretion in vitro. J Clin Invest 97:2534-2540, 1996
30. NIELSEN PK, RASMUSSEN UF, OLGAARD K: A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices hut not from dispersed parathyroid cells. Nephrol Dial Transplant 11:1762-1768, 1996
31. ALMANDEN Y, CANALEJOM A, HERNANDEZ A, BALLESTEROS E, NAVARRO SG, TORRES A, RODRIGUEZ M: Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro. J Bone Miner Res 11:970-976, 1996
32. YAMAMOTO H, YOKOYAMA K, HAYAKAWA H, KATO N, NAKAYAMA M, KUBO H, SHIGEMATSU T, KAWAGUCHI Y, SAKAI O: A rapid increase of serum phosphorus directly raises serum parathyroid hormone in patients with chronic renal failure. (abstract). J Am Soc Nephrol 7:1820, 1996
33. DAWSON HUGHES B, HARRIS SS, FINNERAN S: Calcium absorption on high and low calcium intakes in relation to vitamin D receptor genotype. J Clin Endocrinol Metab 80:3657-3661, 1995
34. PIRAINO B, CHEN T, COOPERSTEIN L, SEGRE G, PUSCHETT J: Renal osteodystrophy in patients on hemodialysis for more than 10 years. Miner Electrolyte Metab 12:390-397, 1986
35. EISENBERG B, TZAMALOUKAS AH, MURATA GH, ELLIOTT TM, JACKSON JE: Factors affecting bone mineral density in elderly men receiving chronic in center hemodialysis. Clin Nucl Med 16:30-41, 1991
36. PEI Y, HERCZ G, GREENWOOD C, SEGRE G, MANUEL A, SAIPHOO C, FENTON S, SHERRARD D: Renal osteodystrophy in diabetic patients. Kidney Int 43:159-164, 1993
37. FLICKER L, LICHTENSTEIN M, COLMAN P, BUIRSKI G, KAYMAKCI B, HOPPER JL, WARK JD: The effect of aging on intact PTH and bone density in women. J Am Geriatrics Soc 40:1135-1138, 1992
38. ATERINI S, SALVADORI M, IPPOLITO E, PETROCELLI P, PACINI S, SINEO L, MARTINI R, FAILLI M, AMATO M, RUGGIERO M: The role of vitamin D receptor gene alleles in the secondary hyperparathyroidism of hemodialysis patients. J Nephrol 9:201-206, 1996
39. CARLING T, KINDMARK A, HELLMAN P, LUNDGREN E, LJUNGHALL S, RASTAD J, AKERSTROM G, MELHUS H: Vitamin D receptor genotypes in primary hyperparathyroidism. Nature Med 1:1309-1311, 1996