The influence of recombinant human erythropoietin on tumor necrosis factor α and interleukin-10 production by whole blood cell cultures in hemodialysis patients

Artificial Organs

Volumn 22, Issue 3, 1998, Pages 177-181

  Bryl, Ewa ^a   Myśliwska, Jolanta ^a   Dȩbska Ślizień, Alicja ^a   Rachoń, Dominik ^a   Bułło, Barbara ^a   Lizakowski, Sławomir ^a   Myśliwski, Andrzej ^a   Rutkowski, Bolesław ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Antiinflammatory cytokines; Erythropoietin; Hemodialysis; Interleukin 10; Proinflammatory cytokines; Tumor necrosis factor

Indexed keywords

BLOOD; CELL CULTURE; DIALYSIS; HEMODIALYZERS; MACROPHAGES; PATIENT TREATMENT; TUMORS;

ANTI-INFLAMMATORIES; ANTIINFLAMMATORY CYTOKINE; CYTOKINES; ERYTHROPOIETIN; HAEMODIALYSIS; HEMODIALYSIS PATIENT; INTERLEUKIN-10; PROINFLAMMATORY CYTOKINES; TUMOR NECROSIS FACTORS; WHOLE BLOOD;

GLYCOPROTEINS;

INTERLEUKIN 10; RECOMBINANT ERYTHROPOIETIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD CELL; CLINICAL ARTICLE; CLINICAL TRIAL; CYTOKINE PRODUCTION; DRUG EFFECT; HEMODIALYSIS PATIENT; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MACROPHAGE ACTIVATION; MONOCYTE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; T LYMPHOCYTE ACTIVATION;

EID: 0031932675     PISSN: 0160564X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1594.1998.06002.x     Document Type: Article

References (27)

1. Revillard JP. Immunological alterations in chronic renal insufficiency. Adv Nephrol 1979;8:365-82.
2. Raska K, Raskova J, Shea SM, Frankel RM, Wood RH. T cell subsets and cellular immunity in end-stage renal disease. Am J Med 1983;75:734-40.
3. Chatenoud L, Dugas B, Beaurain G, Touam M, Drucke T, Vasquez A, Galanoud P, Bach JF, Delfraissy JF. Presence of preactivated T cells in hemodialyzed patients: Their possible role in altered immunity. Proc Natl Acad Sci USA 1986;83: 7457-61.
4. Herbelin A, Urena P, Zingraff J, Descamps-Latscha B. Influence of first long-term dialysis on uremia-associated increased basal production of interleukin-1 and tumor necrosis factor α by circulating monocytes. Nephrol Dial Transplant 1991;6: 349-57.
5. 2-microglobulin. Nephrol Dial Transplant 1991;(Suppl 2):18-23.
6. Cavaillon JM, Poignet JL, Fitting C, Delons S. Serum interleukin-6in long-term hemodialysis patients. Nephron 1991;60: 307-13.
7. 2 by macrophages in uremia. Nephrol Dial Transplant 1991;6:966-70.
8. Beaurain B, Naret C, Marcon L, Grateau G, Drucke T, Urena P, Nelson DL, Bach JF, Chatenoud L. In vivo T cell preactivation in chronic uremic hemodialyzed and non-hemodialyzed patients. Kidney Int 1989;36:636-44.
9. Herbelin A, Nguyen AT, Zingraff J, Urena P, Descamps-Latscha B. Influence of uremia and hemodialysis on circulating interleukin-1 and tumor necrosis factor. Kidney Int 1990; 37:116-25.
10. Andrew OT, Schoenfeld PY, Hopewell C, Hunphreys MH. Tuberculosis in patients with end-stage renal disease. Am J Med 1980;68:59-65.
11. Lindner A, Farewell VT, Sherrard DJ. High incidence of neoplasia in uremic patients receiving long-term dialysis. Nephron 1981;27:292-6.
12. Sethi D, Brown EA, Gower PE. CAPD, protective against developing dialysis-associated amyloid? Nephron 1988;50: 85-6.
13. Sennesael JJ, Van der Niepen P, Verbeelen DL. Treatment with recombinant human erythropoietin increases antibody titers after hepatitis B vaccination in dialysis patients. Kidney Int 1991;40:121-8.
14. Paczek L, Schaefer MR, Heidland A. Improved function of B lymphocytes in dialysis patients treated by recombinant human erythropoietin. In: Schaefer RM. Heidland A, Horl WH, eds. Erythropoietin in the 90s. Basel: Karger, Contrib Nephrol 1990;87:36-41.
15. Imiela J, Korczak-Kowalska G, Małecki R, Nowaczyk M, Stȩpień-Sopniewska B, Górski A. Immunomodulatory action of human recombinant erythropoietin in man. Immunol Lett 1993;35:271-6.
16. Grimm PC, Sinai-Trieman L, Sekiya NM, Robertson LS, Robinson BJ, Fine RN, Ettenger RB. Effect of recombinant human erythropoietin in HLA sensitization and cell mediated immunity. Kidney Int 1990;38:12-8.
17. Barany P, Fehrman I, Godoy C. Long-term effects on lymphocytotoxic antibodies and immune reactivity in hemodialysis patients treated with recombinant human erythropoietin. Clin Nephrol 1992;37:90-6.
18. Buemi M, Allegra A, Alosi C, Fristina N. Influence of therapy with recombinant erythropoietin on serum levels of neopterin in hemodialyzed patients. Am J Nephrol 1991;11:281-3.
19. Kang XX, Hirano T, Oka K, Tamaki T, Sakurai E, Kaji N, Yoshida M, Kozaki M. Recovery of decreased ability of peripheral-blood mononuclear cells from chronic renal failure to produce interleukin-1 and β after renal transplantation. Nephron 1991;58:450-5.
20. Myśliwska J, Bryl E, Szołkiewicz M, Manitius J, Myśliwski A, Rutkowski B. Low doses of recombinant erythropoietin raise serum interleukin-2 levels in hemodialysis patients. J Nephrol 1996;9:30-4.
21. Boswell RN, Yard BA, Schrama E, van Es LA, Daha MR, van der Woude FJ. Interleukin-6 production by human proximal tubular epithelial cells in vitro: Analysis of the effect of interleukin-1α and others cytokines. Nephrol Dial Transplant 1994;9:599-606.
22. Paczek L, Schaefer RM, Heidland A. Dialysis membranes decrease immunoglobulin and interleukin-6 production by peripheral blood mononuclear cells in vitro. Nephrol Dial Transplant 1991;(Suppl. 3):41-4.
23. De Waal Malefyt R, Abrams J, Bennett B, Fidgor C, de Vries JE. IL-10 inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;174:1209-14.
24. Fiorentino DF, Zlotnik A, Mosmann TR, Howard M, O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J Immunol 1991;147:3815-9.
25. De Waal Malefyt R, Haanen J, Spits H, Roncardo MG, te Velde A, Figdor C, Johnson K, Kastelein R, Yssel H, de Vries JE. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991;174:915-24.
26. Burdin N, van Kooten C, Galibert L, Abrams JS, Wijdenes J, Banchereau J, Rousset F. Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 1995;154:2533-44.
27. Itoh K, Hirohata S. The role of IL-10 in human B cell activation, proliferation, and differentiation. J Immunol 1995;154: 4341-50.