Inhibition of N-nitrosation of secondary amines in vitro by tea extracts and catechins

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 412, Issue 1, 1998, Pages 91-98

  Tanaka, Kuniyuki ^a   Hayatsu, Toshiko ^b   Negishi, Tomoe ^b   Hayatsu, Hikoya ^b  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

Catechin; Epigallocatechin; Epigallocatechin gallate; N nitrosation inhibition; Tea extract

Indexed keywords

AMINE; ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; ASCORBIC ACID; CATECHIN; DIMETHYLAMINE; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; MORPHOLINE; NITROSAMINE; PLANT EXTRACT;

ARTICLE; NITROSATION; PRIORITY JOURNAL; TEA;

AMINES; ANIMALS; ANTIMUTAGENIC AGENTS; ASCORBIC ACID; BIOTRANSFORMATION; CATECHIN; JAPAN; MICROSOMES, LIVER; MUTAGENICITY TESTS; NITROSAMINES; NITROSATION; PLANT EXTRACTS; RATS; SALMONELLA TYPHIMURIUM; SODIUM NITRITE; TEA;

CAMELLIA SINENSIS;

EID: 0031932339     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(97)00178-2     Document Type: Article

References (14)

1. Katiyar S.K., Agarwal R., Wood G.S., Mukhtar H. Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea. Cancer Res. 52:1992;6890-6897.
2. Oguni I., Nasu K., Kanaya S., Ota Y., Yamamoto S., Nomura T. Epidemiological and experimental studies on the antitumor activity by green tea extracts. Jpn. J. Nutr. 47:1989;93-102.
3. Wang Z.Y., Khan W.A., Bickers D.R., Mukhtar H. Protection against polycyclic aromatic hydrocarbon-induced skin tumor initiation in mice by green tea polyphenols. Carcinogenesis. 10:1989;411-415.
4. Wang Z.Y., Agarwal R., Bickers D.R., Mukhtar H. Protection against ultraviolet B radiation-induced photocarcinogenesis in hairless mice by green tea polyphenols. Carcinogenesis. 12:1991;1527-1530.
5. Yoshizawa S., Horiuchi T., Fujiki H., Yoshida T., Okuda T., Sugimura T. Antitumor promoting activity of (-)-epigallocatechin gallate, the main constituent of 'tannin' in green tea. Phytother. Res. 1:1987;44-47.
6. H. Bartsch, B. Pignatelli, S. Calmels, H. Ohshima, Inhibition of nitrosation, in: G. Bronzetti, H. Hayatsu, S. De Flora, M. Waters, D. Shankel (Eds.) Antimutagenesis and Anticarcinogenesis Mechanisms III, Plenum, New York, 1993, pp. 27-44.
7. Gichner T., Veleminsky J. Inhibitors of N-nitroso compounds-induced mutagenicity. Mutation Res. 195:1988;21-43.
8. Mirvish S.S., Wallcave L., Eagen M., Shubik P. Ascorbate-nitrite reaction: possible means of blocking the formation of carcinogenic N-nitroso compounds. Science. 177:1972;65-69.
9. Nakamura M., Kawabata T. Effect of Japanese green tea on nitrosamine formation in vitro. J. Food Sci. 46:1981;306-307.
10. Terada K., Suzuki A., Tanaka H., Yamamoto K. Determination of catechins and methylxanthines in foodstuffs by semi-micro high performance liquid chromatography. J. Food Hyg. Soc. Japan. 33:1992;347-354.
11. Tanaka K., Chung K.C., Kada T., Hayatsu H. Inhibition of nitrosamine formation in vitro by sorbic acid. Food Cosmet. Toxicol. 16:1978;209-215.
12. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutation Res. 113:1983;173-215.
13. Graham H.N. Green tea composition, consumption, and polyphenol chemistry. Prev. Med. 21:1992;334-350.
14. Pignatelli B., Bereziat J.C., Descotes G., Bartsch H. Catalysis of nitrosation in vitro and in vivo in rats by catechin and resorcinol and inhibition by chlorogenic acid. Carcinogenesis. 3:1982;1045-1049.