her, a gene required for sexual differentiation in Drosophila, encodes a zinc finger protein with characteristics of ZFY-like proteins and is expressed independently of the sex determination hierarchy

Development

Volumn 125, Issue 2, 1998, Pages 225-235

  Li, Hao ^a   Baker, Bruce S ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Doublesex; Drosophila; Hermaphrodite; Sexual differentiation; ZFY

Indexed keywords

ZINC FINGER PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; GENE; GENE EXPRESSION; HERMAPHRODITISM; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENTIATION;

ABDOMINAL MUSCLES; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; CAENORHABDITIS ELEGANS PROTEINS; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; HELMINTH PROTEINS; INSECT PROTEINS; MALE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; RNA SPLICING; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SEX DETERMINATION (GENETICS); SEX DIFFERENTIATION; TRANSCRIPTION FACTORS; ZINC FINGERS;

ANIMALIA; HEXAPODA; VERTEBRATA;

EID: 0031931932     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Amrein, H., Gorman, M. and Nöthiger, R. (1988). The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein. Cell 55, 1025-1035.
2. Anderson, K. V. and Lengyel, J. A. (1981). Changing rates of DNA and RNA synthesis in Drosophila embryos. Dev. Biol. 82, 127-138.
3. Ashburner, M. (1989). Drosophila: a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
4. Ashburner, M., Thompson, P., Roote, J., Lasko, P. F., Grau, Y., El Messal, M., Roth, S. and Simpson, P. (1990). The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. VII. Characterization of the region around the snail and cactus loci. Genetics 126, 679-694.
5. Baker, B. S., Gorman, M. and Marin, I. (1994). Dosage compensation in Drosophila. Annu. Rev. Genet. 28, 491-521.
6. Baker, B. S. and Ridge, K. (1980). Sex and the single cell: On the action of major loci affecting sex determination in Drosophila melanogaster. Genetics 94, 383-423.
7. Bownes, M. (1994). The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster. Bioessays 16, 745-752.
8. Burtis, K. C. (1993). The regulation of sex determination and sexually dimorphic differentiation in Drosophila. Curr. Opin. Cell. Biol. 5, 1006-1014.
9. Burtis, K. C., Coschigano, K. T., Baker, B. S. and Wensink, P. C. (1991). The doublesex proteins of Drosophila melanogaster bind directly to a sex-specific yolk protein gene enhancer. EMBO J. 10, 2577-2582.
10. Burtis, K. C. and Wolfner, M. F. (1992). The view from the bottom: Sex-specific traits and their control in Drosophila. Semin. Dev. Biol. 3, 331-340.
11. Cai, H., Kiefel, P., Yee, J. and Duncan, I. (1994). A yeast artificial chromosome clone map of the Drosophila genome. Genetics 136, 1385-1399.
12. Chase, B. A. and Baker, B. S. (1995). A genetic analysis of intersex, a gene regulating sexual differentiation in Drosophila melanogaster females. Genetics 139, 1649-1661.
13. Chong, J. A., Tapia-Ramirez, J., Kim, S., Toledo-Aral, J. J., Zheng, Y., Boutros, M. C., Altshuller, Y. M., Frohman, M. A., Kraner, S. D. and Mandel, G. (1995). REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80, 949-957.
14. Cline, T. W. and Meyer, B. J. (1996). VIVE LA DIFFÉRENCE: Males vs Females in Flies vs Worms. Annu. Rev. Genet. 30, 637-702.
15. Davis, R. L. and Davidson, N. (1984). Isolation of the Drosophila melanogaster dunce chromosomal region and recombinational mapping of dunce sequences with restriction site polymorphisms as genetic markers. Mol. Cell. Biol. 4, 358-367.
16. DiAntonio, A., Burgess, R. W., Chin, A. C., Deitcher, D. L., Scheller, R. H. and Schwarz, T. L. (1993). Identification and characterization of Drosophila genes for synaptic vesicle proteins. J. Neurosci. 13, 4924-4935.
17. Dilella, A. G., Page, D. C. and Smith, R. G. (1990). A bird zinc-finger protein closely related to ZFY. New Biol. 2, 49-56.
18. Erdman, S. E., Chen, H. and Burtis, K. C. (1996). Functional and genetic characterization of the oligomerization and DNA binding properties of the Drosophila doublesex proteins. Genetics 144, 1639-1652.
19. Filippova, G. N., Fagerlie, S., Klenova, E. M., Myers, C., Dehner, Y., Goodwin, G., Neiman, P. E., Collins, S. J. and Lobanenkov, V. V. (1996). An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol. Cell. Biol. 16, 2802-2813.
20. Gailey, D. A., Taylor, B. J. and Hall, J. C. (1991). Elements of the fruitless locus regulate development of the muscle of Lawrence, a male-specific structure in the abdomen of Drosophila melanogaster adults. Development 113, 879-890.
21. Gibson, T. J., Postma, J. P., Brown, R. S. and Argos, P. (1988). A model for the tertiary structure of the 28 residue DNA-binding motif ('zinc finger') common to many eukaryotic transcriptional regulatory proteins. Protein Eng. 2, 209-218.
22. Goodfellow, P. D. and Lovell-Badge, R. (1993). Sry and sex determination in mammals. Annu. Rev. Genet. 27, 71-92.
23. Goralski, T. J., Edstrom, J. E. and Baker, B. S. (1989). The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins. Cell 56, 1011-1018.
24. Granadino, B., Penalva, L. O. F. and Sánchez, L. (1996). The gene fl(2)D is needed for the sex-specific splicing of transformer pre-messenger-RNA in Drosophila melanogaster. Mol. Gen. Genet. 253, 26-31.
25. Hall, J. C. (1994). The mating of a fly. Science 264, 1702-1714.
26. Horabin, J. I. and Schedl, P. (1993). Sex-lethal autoregulation requires multiple cis-acting elements upstream and downstream of the male exon and appears to depend largely on controlling the use of the male exon 5′ splice site. Mol. Cell. Biol. 13, 7734-7746.
27. Innis, M. A., Gelfand, D. H., Sninsky, J. J. and White, T. J. (1990). PCR Protocols: a Guide to Methods and Applications. San Diego: Academic Press, Inc.
28. Ito, H., Fujitani, K., Usui, K., Shimizu-Nishikawa, K., Tanaka, K. and Yamamoto, K. (1996). Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain. Proc. Natl. Acad. Sci. USA 93, 9687-9692.
29. Jursnich, V. A. and Burtis, K. C. (1993). A positive role in differentiation for the male doublesex protein of Drosophila. Dev. Biol. 155, 235-249.
30. Klenova, E. M., Nicolas, R. H., Paterson, H. F., Carne, A. F., Heath, C. M., Goodwin, G. H., Neiman, P. E. and Lobanenkov, V. V. (1993). CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms. Mol. Cell. Biol. 13, 7612-7624.
31. Klug, A. and Schwabe, J. W. R. (1995). Zinc fingers. FASEB J. 9, 597-604.
32. Kochoyan, M., Keutmann, H. T. and Weiss, M. A. (1991). Alternating zinc-fingers in the human male associated protein ZFY: refinement of the NMR structure of an even finger by selective deuterium labeling and implications for DNA recognition. Biochemistry 30, 7063-7072.
33. Krizek, B. A., Amann, B. T., Kilfoil, V. J., Merkle, D. L. and Berg, J. M. (1991). A consensus zinc finger peptide: Design, high-affinity metal binding, a pH-dependent structure, and a His to Cys sequence variant. J. Amer. Chem. Soc. 113, 4518-4523.
34. Lamond, A. I. (1995). Pre-mRNA processing. R. G. Landes Company, Austin, Texas.
35. Lawrence, P. A. and Johnston, P. (1986). The muscle pattern of a segment of Drosophila may be determined by neurons and not by contributing myoblasts. Cell 45, 505-513.
36. Mahowald, A. P. and Wei, G. (1994). Sex determination of germ cells in Drosophila. Ciba. Found. Symp. 182, 193-202; discussion 202-209.
37. Mattox, W., Palmer, M. J. and Baker, B. S. (1990). Alternative splicing of the sex determination gene transformer-2 is sex-specific in the germ line but not in the soma. Genes Dev. 4, 789-805.
38. McKeown, M. (1992). Alternative messenger-RNA splicing. Ann. Rev. Cell. Biol. 8, 133-155.
39. McKeown, M., Belote, J. M. and Boggs, R. T. (1988). Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male Drosophila. Cell 53, 887-895.
40. McKeown, M. and Madigan, S. J. (1992). Sex determination and differentiation in invertebrates: Drosophila and Caenorhabditis elegans. Curr. Opin. Cell. Biol. 4, 948-954.
41. Nagoshi, R. N., Mckeown, M., Burtis, K. C., Belote, J. M. and Baker, B. S. (1988). The control of alternative splicing at genes regulating sexual differentiation in Drosophila melanogaster. Cell 53, 229-236.
42. Parkhurst, S. M. and Meneely, P. M. (1994). Sex determination and dosage compensation: lessons from flies and worms. Science 264, 924-932.
43. Pirrotta, V. (1988). Vectors for P-mediated transformation in Drosophila. In Vectors, a Survey of Molecular Cloning Vectors and their Uses (ed. R. L. Rodriguez and D. T. Denhardt), pp. 437-456. Butterworths, Boston, MA.
44. Pultz, M. A. and Baker, B. S. (1995). The dual role of hermaphrodite in the Drosophila sex determination regulatory hierarchy. Development 121, 99-111.
45. Pultz, M. A., Carson, G. S. and Baker, B. S. (1994). A genetic analysis of hermaphrodite, a pleiotropic sex determination gene in Drosophila melanogaster. Genetics 136, 195-207.
46. Redfield, H. (1924). A case of maternal inheritance in Drosophila. Amer. Nat. 58, 566-569.
47. Robertson, H. M., Preston, C. R., Phillis, R. W., Johnson-Schlitz, D. M., Benz, W. K. and Engels, W. R. (1988). A stable genomic source of P element transposase in Drosophila melanogaster. Genetics 118, 461-470.
48. Rubin, G. and Spradling, A. (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.
49. Ryner, L., Goodwin, S. F., Castrillon, D. H., Anand, A., Villella, A., Baker, B. S., Hall, J. C., Taylor, B. J. and Wassserman, S. A. (1996). Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene. Cell 87, 1079-1089.
50. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
51. Sánchez, L., Granadino, B. and Torres, M. (1994). Sex determination in Drosophila melanogaster: X-linked genes involved in the initial step of Sex-lethal activation. Dev. Genet. 15, 251-264.
52. Schafer, A. J. (1995). Sex determination and its pathology in man. Adv. Genet. 33, 275-329.
53. Spradling, A. and Rubin, G. (1982). Transposition of cloned P elements into Drosophila germ line chromosomes. Science 218, 341-347.
54. Taylor, B. J. (1992). Differentiation of a male-specific muscle in Drosophila melanogaster does not require the sex-determining genes doublesex or intersex. Genetics 132, 179-191.
55. Taylor, B. J. and Truman, J. W. (1992). Commitment of abdominal neuroblasts in Drosophila to a male or female fate is dependent on genes of the sex-determining hierarchy. Development 114, 625-642.
56. Taylor, B. J., Villella, A., Ryner, L. C., Baker, B. S. and Hall, J. C. (1994). Behavioral and neurobiological implications of sex-determining factors in Drosophila. Dev. Genet. 15, 275-296.
57. Thaker, H. M. and Kankel, D. R. (1992). Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster. Genetics 131, 883-894.
58. Villares, R. and Cabrera, C. V. (1987). The achaete-scute gene complex of D. melangaster: Conserved domains in a subset of genes required for neurogenesis and their homology to myc. Cell 50, 415-424.
59. Villella, A. and Hall, J. C. (1996). Courtship anomalies caused by doublesex mutations in Drosophila melanogaster. Genetics 143, 331-344.
60. Zambrowicz, B. P., Zimmermann, J. W., Harendza, C. J., Simpson, E. M., Page, D. C., Brinster, R. L. and Palmiter, R. D. (1994). Expression of a mouse zfy-1/lacZ transgene in the somatic cells of the embryonic gonad and germ cells of the adult testis. Development 120, 1549-1559.
61. Zeller, R. W., Britten, R. J. and Davidson, E. H. (1995). Developmental utilization of SpP3A1 and SpP3A2: two proteins which recognize the same DNA target site in several sea urchin gene regulatory regions. Dev. Biol. 170, 75-82.