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The PAX2 transcription factor is expressed in cystic and hyperproliferative dysplastic epithelia in human kidney malformations
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Winyard PJD, Risdon RA, Sams VR, Dressler GR, Woolf AS: The PAX2 transcription factor is expressed in cystic and hyperproliferative dysplastic epithelia in human kidney malformations. J Clin Invest 1996;98:451-459.
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Unravelling the genetics of vesicoureteric reflux: A common familial disorder
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PAX8, a human paired box gene: Isolation and expression in developing thyroid, kidney and Wilms' tumors
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PAX8, a murine paired box gene expressed in the developing excretory system and thyroid gland
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Expression of the PAX2 gene in human fetal kidney and Wilms' tumor
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Eccles MR, Wallis LJ, Fidler AF, Spurr NK, Goodfellow PJ, Reeve AE: Expression of the PAX2 gene in human fetal kidney and Wilms' tumor. Cell Growth Different 1992;3:279-289.
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Alternative messenger RNA form and open reading frames within an additional conserved region of the human PAX2 gene
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Ward TA, Nebel A, Reeve AE, Eccles MR: Alternative messenger RNA form and open reading frames within an additional conserved region of the human PAX2 gene. Cell Growth Different 1994;5:1015-1021.
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Alternative splicing of PAX8 transcripts is developmentally regulated and generates isoforms with different transactivation properties
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Kozmik Z, Kurzbauer P, Dopfler P, Busslinger M: Alternative splicing of PAX8 transcripts is developmentally regulated and generates isoforms with different transactivation properties. Mol Cell Biol 1993;13:6024-6035.
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Deregulation of PAX2 expression in transgenic mice denerates severe kidney abnormalities
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Dressler GR, Wilkinson E, Rothenpieler U, Patterson L, Williams-Simons L, Westphal H: Deregulation of PAX2 expression in transgenic mice denerates severe kidney abnormalities. Nature 1993;362:65-67.
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Mutation of the PAX2 gene in a family with optic nerve colobomas, renal abnormalities and vesicoureteral reflux
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Sanyanusin P, Schimmenti L, McNoe L, Ward T, Pierpont M, Sullivan M, Dobyns W, Eccles MR: Mutation of the PAX2 gene in a family with optic nerve colobomas, renal abnormalities and vesicoureteral reflux. Nature Genet 1995;9:358-363.
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Mutation of PAX2 in two siblings with renal-coloboma syndrome
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Sanyanusin P, McNoe LA, Sullivan MJ, Weaver RG, Eccles MR: Mutation of PAX2 in two siblings with renal-coloboma syndrome. Human Mol Genet 1995;4:2183-2184.
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The mouse PAX2 (1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney
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Favour J, Sandulache R, Neuhauser-Klaus A, Pretsch W, Chatterjee B, Senft E, Worst W, Blanquet V, Grimes P, Sporle R, Schughart K: The mouse PAX2 (1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney. PNAS 1996;93:13870-13875.
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Expression of PAX2 in human renal carcinoma and growth inhibition by antisense oligonucleotides
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Gnarra JR, Gressler GR: Expression of PAX2 in human renal carcinoma and growth inhibition by antisense oligonucleotides. Cancer Res 1995;55:4092-4098.
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The oncogenic potential of PAX genes
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Repression of PAX-2 by WT1 during normal kidney development
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Ryan G, Steele-Perkins V, Morris JF, Rauscher FJ III, Dressler GR: Repression of PAX-2 by WT1 during normal kidney development. Development 1995;121:867-875.
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PAX8-mediated activation of the WT1 tumor suppressor gene
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The paired-box transcription factor, PAX2, positively modulates expression of the Wilms" tumor suppressor gene (WT1)
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Dehbi M, Ghahremani M, Lechner M, Dressler GR, Pelletier J: The paired-box transcription factor, PAX2, positively modulates expression of the Wilms" tumor suppressor gene (WT1). Oncogene 1996;13:447-453.
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PAX2 is required for mesenchyme-to-epithelium conversion during kidney development
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Rothenpieler U, Dressler GR: PAX2 is required for mesenchyme-to-epithelium conversion during kidney development. Development 1993;119:711-720.
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