메뉴 건너뛰기




Volumn 27, Issue 1, 1998, Pages 1-6

Antibodies to DNA - Towards an understanding of their origin and pathophysiological impact in systemic lupus erythematosus

Author keywords

Anti DNA antibodies; B cells; DNA immunogenicity; Pathophysiology; SLE; T cells

Indexed keywords

AUTOANTIBODY; DNA; DNA ANTIBODY; HISTONE; VIRUS LARGE T ANTIGEN;

EID: 0031931521     PISSN: 03009742     EISSN: None     Source Type: Journal    
DOI: 10.1080/030097498441100     Document Type: Review
Times cited : (15)

References (42)
  • 1
    • 0028189658 scopus 로고
    • Anti-DNA antibodies - Some enigma variations
    • Isenberg DA. Anti-DNA antibodies - some enigma variations. The Immunologist 1994;2:190-3.
    • (1994) The Immunologist , vol.2 , pp. 190-193
    • Isenberg, D.A.1
  • 2
    • 0028292951 scopus 로고
    • Genetic and structural evidence for antigen selection of anti-DNA antibodies
    • Radic MZ, Weigert M. Genetic and structural evidence for antigen selection of anti-DNA antibodies. Annu Rev Immunol 1994;12:487-520.
    • (1994) Annu Rev Immunol , vol.12 , pp. 487-520
    • Radic, M.Z.1    Weigert, M.2
  • 3
    • 0026612988 scopus 로고
    • Selection of immunoglobulin variable regions in autoimmunity to DNA
    • 1992
    • Marion TN, Tillman DM, Jou N-T, Hill RJ. 1992. Selection of immunoglobulin variable regions in autoimmunity to DNA. Immunol Rev 1992;128:123-49.
    • (1992) Immunol Rev , vol.128 , pp. 123-149
    • Marion, T.N.1    Tillman, D.M.2    Jou, N.-T.3    Hill, R.J.4
  • 6
    • 0026740330 scopus 로고
    • Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas
    • Winkler TH, Fehr H, Kalden JR. Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas. Eur J Immunol 1992;22:1719-28.
    • (1992) Eur J Immunol , vol.22 , pp. 1719-1728
    • Winkler, T.H.1    Fehr, H.2    Kalden, J.R.3
  • 8
    • 0023718496 scopus 로고
    • V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice
    • Eilat D, Webster DM, Rees AR. V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice. J Immunol 1988;141:1745-53.
    • (1988) J Immunol , vol.141 , pp. 1745-1753
    • Eilat, D.1    Webster, D.M.2    Rees, A.R.3
  • 10
    • 0027532192 scopus 로고
    • B lymphocytes may escape tolerance by revising their antigen receptors
    • Radic MZ, Erikson J, Litwin S, Weigert M. B lymphocytes may escape tolerance by revising their antigen receptors. J Exp Med 1993;177:1165-73.
    • (1993) J Exp Med , vol.177 , pp. 1165-1173
    • Radic, M.Z.1    Erikson, J.2    Litwin, S.3    Weigert, M.4
  • 12
    • 0026490766 scopus 로고
    • Immunochemical analyses of nucleic acids
    • Stollar BD. Immunochemical analyses of nucleic acids. Prog Nucleic Acid Res Mol Biol 1992;42:39-77.
    • (1992) Prog Nucleic Acid Res Mol Biol , vol.42 , pp. 39-77
    • Stollar, B.D.1
  • 13
  • 14
    • 0027182519 scopus 로고
    • Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice
    • Desai DD, Krishnan MR, Swindle JT, Marion TN. Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice. J Immunol 1993;151:1614-26.
    • (1993) J Immunol , vol.151 , pp. 1614-1626
    • Desai, D.D.1    Krishnan, M.R.2    Swindle, J.T.3    Marion, T.N.4
  • 15
    • 0027232793 scopus 로고
    • Structural similarity of antibody variable regions from immune and autoimmune anti-DNA antibodies
    • Krishnan MR, Marion TN. Structural similarity of antibody variable regions from immune and autoimmune anti-DNA antibodies. J Immunol 1993;150:4948-57.
    • (1993) J Immunol , vol.150 , pp. 4948-4957
    • Krishnan, M.R.1    Marion, T.N.2
  • 16
    • 0029558337 scopus 로고
    • In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones
    • Moens U, Seternes O-M, Hey AW, Silsand Y, Traavik T, Johansen B, et al. In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones. Proc Natl Acad Sci USA 1995;92:12393-7.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12393-12397
    • Moens, U.1    Seternes, O.-M.2    Hey, A.W.3    Silsand, Y.4    Traavik, T.5    Johansen, B.6
  • 17
    • 0030951002 scopus 로고    scopus 로고
    • Experimental expression in mice and spontaneous expression in human SLE of polyomavirus T-antigen: A molecular bases for induction of antibodies to DNA and eukaryotic transcription factors
    • Rekvig OP, Moens U, Sundsfjord A, Bredholt G, Osei A, Haaheim H, et al. Experimental expression in mice and spontaneous expression in human SLE of polyomavirus T-antigen: a molecular bases for induction of antibodies to DNA and eukaryotic transcription factors. J Clin Invest 1997;99:2045-54.
    • (1997) J Clin Invest , vol.99 , pp. 2045-2054
    • Rekvig, O.P.1    Moens, U.2    Sundsfjord, A.3    Bredholt, G.4    Osei, A.5    Haaheim, H.6
  • 19
    • 0031001840 scopus 로고    scopus 로고
    • Human polyomavirus BK and immunogenicity of mammalian DNA:A conceptual framework
    • Rekvig OP, Moens U, Fredriksen K, Traavik T. Human polyomavirus BK and immunogenicity of mammalian DNA:A conceptual framework. Methods 1997;11:44-54.
    • (1997) Methods , vol.11 , pp. 44-54
    • Rekvig, O.P.1    Moens, U.2    Fredriksen, K.3    Traavik, T.4
  • 20
    • 0023733505 scopus 로고
    • Inoculation of BK virus may lead to break of immunological tolerance to histone and DNA antigens
    • Flaegstad T, Fredriksen K, Dahl B, Traavik T. Rekvig OP. Inoculation of BK virus may lead to break of immunological tolerance to histone and DNA antigens. Proc Natl Acad Sci USA 1988;85:8171-5.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8171-8175
    • Flaegstad, T.1    Fredriksen, K.2    Dahl, B.3    Traavik, T.4    Rekvig, O.P.5
  • 21
    • 0028139987 scopus 로고
    • On the biological origin of anti-double-stranded (ds) DNA antibodies: Systemic lupus erythematosus-related anti-dsDNA antibodies are induced by polyomavirus BK in lupus-prone (NZB × NZW) F1 hybrids, but not in normal mice
    • Fredriksen K, Osei A, Sundsfjord A, Traavik T, Rekvig OP. On the biological origin of anti-double-stranded (ds) DNA antibodies: systemic lupus erythematosus-related anti-dsDNA antibodies are induced by polyomavirus BK in lupus-prone (NZB × NZW) F1 hybrids, but not in normal mice. Eur J Immunol 1994;24:66-70.
    • (1994) Eur J Immunol , vol.24 , pp. 66-70
    • Fredriksen, K.1    Osei, A.2    Sundsfjord, A.3    Traavik, T.4    Rekvig, O.P.5
  • 22
    • 0030663853 scopus 로고    scopus 로고
    • Mechanisms of transcriptional regulation of cellular genes by SV40 large T- and small T-antigens
    • Moens U, Seternes OM, Johansen B, Rekvig OP. Mechanisms of transcriptional regulation of cellular genes by SV40 large T- and small T-antigens. Virus Genes 1997;15:135-54.
    • (1997) Virus Genes , vol.15 , pp. 135-154
    • Moens, U.1    Seternes, O.M.2    Johansen, B.3    Rekvig, O.P.4
  • 23
  • 24
    • 0027477318 scopus 로고
    • Nucleosome:A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan C, Adams S. Stanik V, Datta SK. Nucleosome:A major immunogen for pathogenic autoantibody-inducing T cells of lupus. J Exp Med 1993;177:1367-81.
    • (1993) J Exp Med , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 25
    • 0028798616 scopus 로고
    • Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus
    • Desai-Mehta A, Mao C, Rajagopalan S, Robinson T, Datta SK. Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus. J Clin Invest 1995;95:531-41.
    • (1995) J Clin Invest , vol.95 , pp. 531-541
    • Desai-Mehta, A.1    Mao, C.2    Rajagopalan, S.3    Robinson, T.4    Datta, S.K.5
  • 26
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan C, Shi Y, Laman JD, Datta SK. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol 1995;154:1470-80.
    • (1995) J Immunol , vol.154 , pp. 1470-1480
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 27
    • 0018072901 scopus 로고
    • Spontaneous murine lupus-like syndromes. Clinical and immunopathophysiological manifestations in several strains
    • Andrews BS, Eisenberg RA, Theophilopoulos AN, Izui S, Wilson CB, McConahey PJ, et al. Spontaneous murine lupus-like syndromes. Clinical and immunopathophysiological manifestations in several strains. J Exp Med 1978;148: 1198-215.
    • (1978) J Exp Med , vol.148 , pp. 1198-1215
    • Andrews, B.S.1    Eisenberg, R.A.2    Theophilopoulos, A.N.3    Izui, S.4    Wilson, C.B.5    McConahey, P.J.6
  • 28
    • 0021342845 scopus 로고
    • The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-DNA antibodies in NZB/W mice
    • Dang H, Harbeck RJ. The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-DNA antibodies in NZB/W mice. Clin Immunol Immunopathol 1984; 30:265-78.
    • (1984) Clin Immunol Immunopathol , vol.30 , pp. 265-278
    • Dang, H.1    Harbeck, R.J.2
  • 29
    • 0015095932 scopus 로고
    • Antibodies to polynucleotides in human sera: Antigen specificity and relation to disease
    • Koffler D, Carr R, Agnello V, Thoburn R, Kunkel HG. Antibodies to polynucleotides in human sera: antigen specificity and relation to disease. J Exp Med 1971;134:294-312.
    • (1971) J Exp Med , vol.134 , pp. 294-312
    • Koffler, D.1    Carr, R.2    Agnello, V.3    Thoburn, R.4    Kunkel, H.G.5
  • 31
    • 0029893337 scopus 로고    scopus 로고
    • Lupus autoantibodies interact directly with distinct glomerular and vascular cell surface antigens
    • D'Andrea DM. Coupaye-Gerard B, Kleyman TR, Foster MH, Madaio MP. Lupus autoantibodies interact directly with distinct glomerular and vascular cell surface antigens. Kidney Int 1996;49:1214-21.
    • (1996) Kidney Int , vol.49 , pp. 1214-1221
    • D'Andrea, D.M.1    Coupaye-Gerard, B.2    Kleyman, T.R.3    Foster, M.H.4    Madaio, M.P.5
  • 32
    • 0027518589 scopus 로고
    • Cross-reactions of anti-DNA autoantibodies with cell surface proteins
    • Raz E, Ben-Bassat H, Davidi T, Shlomai Z, Eilat D. Cross-reactions of anti-DNA autoantibodies with cell surface proteins. Eur J Immunol 1993;23:383-90.
    • (1993) Eur J Immunol , vol.23 , pp. 383-390
    • Raz, E.1    Ben-Bassat, H.2    Davidi, T.3    Shlomai, Z.4    Eilat, D.5
  • 33
    • 0028609559 scopus 로고
    • Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies
    • Foster MH, Kieber-Emmons T, Ohliger M, Madaio MP. Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies. Immunol Res 1994;13:186-206.
    • (1994) Immunol Res , vol.13 , pp. 186-206
    • Foster, M.H.1    Kieber-Emmons, T.2    Ohliger, M.3    Madaio, M.P.4
  • 34
    • 0029822118 scopus 로고    scopus 로고
    • Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells
    • Madaio MP, Fabbi M, Tiso M. Daga A. Puccetti A. Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells. Eur J Immunol 1996;26:3035-41.
    • (1996) Eur J Immunol , vol.26 , pp. 3035-3041
    • Madaio, M.P.1    Fabbi, M.2    Tiso, M.3    Daga, A.4    Puccetti, A.5
  • 35
    • 0030971352 scopus 로고    scopus 로고
    • Antigen specificity of anti-nuclear antibodies complexed to nucleosomes determines glomerular basement membrane binding in vivo
    • van Bruggen MC, Walgreen B, Rijke TP, Tamboer W, Kramers K, Smeenk RJ, et al. Antigen specificity of anti-nuclear antibodies complexed to nucleosomes determines glomerular basement membrane binding in vivo. Eur J Immunol 1997;27:564-9.
    • (1997) Eur J Immunol , vol.27 , pp. 564-569
    • Van Bruggen, M.C.1    Walgreen, B.2    Rijke, T.P.3    Tamboer, W.4    Kramers, K.5    Smeenk, R.J.6
  • 37
    • 0028015572 scopus 로고
    • Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo
    • Kramers C, Hylkema MN, van Bruggen MC, van de Lagemaat R, Dijkman HB, Assmann KJ, et al. Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo. J Clin Invest 1994;94:568-77.
    • (1994) J Clin Invest , vol.94 , pp. 568-577
    • Kramers, C.1    Hylkema, M.N.2    Van Bruggen, M.C.3    Van De Lagemaat, R.4    Dijkman, H.B.5    Assmann, K.J.6
  • 38
    • 0017084411 scopus 로고
    • In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus
    • Izui S, Lambert PH, Miescher PA. In vitro demonstration of a particular affinity of glomerular basement membrane and collagen for DNA. A possible basis for a local formation of DNA-anti-DNA complexes in systemic lupus erythematosus. J Exp Med 1976;144:428-43.
    • (1976) J Exp Med , vol.144 , pp. 428-443
    • Izui, S.1    Lambert, P.H.2    Miescher, P.A.3
  • 39
    • 0024506642 scopus 로고
    • Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney
    • Raz E. Brezis M, Rosenmann E. Eilat D. Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney. J Immunol 1989; 142:3076-82.
    • (1989) J Immunol , vol.142 , pp. 3076-3082
    • Raz, E.1    Brezis, M.2    Rosenmann, E.3    Eilat, D.4
  • 40
    • 0029822118 scopus 로고    scopus 로고
    • Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells
    • Madaio MP, Fabbi M, Tiso M, Daga A, Puccetti A. Spontaneously produced anti-DNA/DNase I autoantibodies modulate nuclear apoptosis in living cells. Eur J Immunol 1996;26:3035-41.
    • (1996) Eur J Immunol , vol.26 , pp. 3035-3041
    • Madaio, M.P.1    Fabbi, M.2    Tiso, M.3    Daga, A.4    Puccetti, A.5
  • 41
    • 0028059883 scopus 로고
    • A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time- and temperature-dependent manner
    • Yanase K, Smith RM, Cizman B, Foster MH, Peachey LD, Jarett L, et al. A subgroup of murine monoclonal anti-deoxyribonucleic acid antibodies traverse the cytoplasm and enter the nucleus in a time- and temperature-dependent manner. Lab Invest 1994;71:52-60.
    • (1994) Lab Invest , vol.71 , pp. 52-60
    • Yanase, K.1    Smith, R.M.2    Cizman, B.3    Foster, M.H.4    Peachey, L.D.5    Jarett, L.6
  • 42
    • 0029871831 scopus 로고    scopus 로고
    • Emerging concepts regarding B cells and autoantibodies in murine lupus nephritis. B cells have multiple roles; all autoantibodies are not equal
    • Madaio MP, Shlomchik MJ. Emerging concepts regarding B cells and autoantibodies in murine lupus nephritis. B cells have multiple roles; all autoantibodies are not equal [editorial]. J Am Soc Nephrol 1996;7:387-96.
    • (1996) J Am Soc Nephrol , vol.7 , pp. 387-396
    • Madaio, M.P.1    Shlomchik, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.