Biochemical analysis of the CD45-p56(lck) complex in Jurkat T cells lacking expression of lymphocyte phosphatase-associated phosphoprotein

International Immunology

Volumn 10, Issue 2, 1998, Pages 185-194

  Bruyns, Eddy ^a   Kirchgessner, Henning ^a   Meuer, Stefan ^a   Schraven, Burkhart ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

CD45; Lymphocyte phosphatase associated phosphoprotein; p56(lck); Signal transduction; T lymphocytes

Indexed keywords

CD45 ANTIGEN; PHOSPHATASE; PHOSPHOPROTEIN;

ARTICLE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANTIGENS, CD45; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HLA-A2 ANTIGEN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MOLECULAR WEIGHT; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEINS; PHOSPHOTYROSINE; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES;

EID: 0031931137     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.2.185     Document Type: Article

References (46)

1. Thomas, M. L. 1989. The leukocyte common antigen family. Annu. Rev. Immunol. 7:339.
2. Streuli, M., Hall, L. R., Saga, Y., Schlossman, S. F. and Saito, H. 1987. Differential usage of three exons generates at least five different mRNAs encoding human leucocyte common antigen. J. Exp. Med. 166:1548.
3. Streuli, M., Matasuyama, T., Morimoto, C., Schlossman, S. F. and Saito, H. 1987. Identification of the sequence required for expression of the 2H4 epitope on the human leucocyte common antigens. J. Exp. Med. 166:1567.
4. Thomas, M. L. and Lefrancois, L. 1988. Differential expression of the leucocyte common antigen family. Immunol. Today 9:320.
5. Charbonneau, H., Tonks, N. K., Walsh, K. A. and Fischer, E. H. 1988. The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase. Proc. Natl Acad. Sci. USA 85:7182.
6. Tonks, N. K., Charbonneau, H., Diltz, C. D., Fischer, E. H. and Walsh, K. A. 1988. Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase. Biochemistry 27:8695.
7. Clark, E. A. and Ledbetter, J. A. 1989. Leucocyte cell surface enzymology: CD45 (LCA, T200) is a protein tyrosine phosphatase. Immunol Today 10:225.
8. Tonks, N. K., Diltz, C. D. and Fischer, E. H. 1990. CD45, an integral membrane protein tyrosine phosphatase. J. Biol. Chem. 265:10674.
9. Pingel, J. T. and Thomas, M. 1989. Evidence that the leucocyte-common antigen is required for antigen-induced T lymphocyte proliferation. Cell 58:1055.
10. + T cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T cell receptor stimuli. Mol. Cell Biol. 11:4415.
11. Peyron, J.-F., Verma, S., de Waal malefyt, R., Sancho, J., Terhorst, C. and Spits, H. 1991. The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line. Int. Immunol. 3:1357.
12. Koretzky, G. A., Picus, J., Thomas, M. L. and Weiss, A. 1990. Tyrosine phosphatase CD45 is essential for coupling T cell antigen receptor to the phosphatidyl inositol pathway. Nature 346:66.
13. Koretzky, G. A., Picus, J., Schultz, T. and Weiss, A. 1991. Tyrosine phosphatase CD45 is required for T cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc. Natl Acad. Sci. USA 88:2037.
14. 2+ oscillations. J. Exp. Med. 176:835.
15. Desai, D. M., Sap, J., Schlessinger, J. and Weiss, A. 1993. Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell 73:541.
16. Hovis, R. R., Donovan, J. A., Musci, M. A., Motto, D. G., Goldman, F. D., Ross, S. E. and Koretzky, G. A. 1993. Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45. Science 260:544.
17. Volaveric, S., Nikilinska, B. B., Burns, C. M., June, C. H., Weissman, A. M. and Ashwell, J. D. 1993. Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains. Science 260:541.
18. fyn). Cell 65:281.
19. Appleby, M. W., Gross, J. A., Cooke, M. P., Levin, S. D., Qian, X. and Perlmutter, R. M. 1992. Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70:751.
20. Stein, P. L., Lee, H.-M., Rich, S. and Soriano, P. 1992. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70:741.
21. lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70:585.
22. lck and pp32, a possible common substrate. Eur. J. Immunol. 21:2469.
23. lck associated phosphoproteins (pp29-pp32) undergo alterations in human T cell activation. Eur J. Immunol. 22:1857.
24. Mustelin, T., Pessa-Morikawa, T., Autero, M., Gassman, M., Andersson, L. C., Gahmberg, C. G. and Burn, P. 1992. Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase. Eur. J. Immunol. 22:1173.
25. Koretzky, G. A., Kohmetscher, M. and Ross, S. 1993. CD45-associated kinase activity requires lck but not T cell receptor expression in Jurkat T cell line. J. Biol. Chem. 268:8958.
26. Rudd, C. E., Janssen, O., Prasad, K. V. S., Raab, M., da Silva, A., Telfer, J. C. and Yamamoto, M. 1993. src-related protein tyrosine kinases and their surface receptors. Biochim. Biophys. Acta 1155:239.
27. Mustelin, T. and Burn, P. 1993. Regulation of src family tyrosine kinases in lymphocytes. Trends Biochem. Sci. 18:215.
28. Cahir McFarland, E. D., Hurley, T. R., Pingel, J. T., Sefton, B. M., Shaw, A. and Thomas, M. L. 1993. Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T cell receptor. Proc. Natl Acad. Sci. USA 90:1402.
29. Sieh, M., Bolen, J. B. and Weiss, A. 1993. CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. EMBO. J. 12:315.
30. Ostergaard, H. L., Shackelford, D. A., Hurley, T. R., Johnson, P., Hyman, R., Sefton, B. M. and Trowbridge, I. S. 1989. Expression of CD45 alters phosphorylation of the lck-encoded tyrosine kinase in murine lymphoma T cell lines. Proc. Natl Acad. Sci. USA 86:8959.
31. lck by the CD45 phosphotyrosine phosphatase. Proc. Natl Acad. Sci. USA 86:6302.
32. Mustelin, T. and Altman, A. 1990. Dephosphorylation and activation of the T cell tyrosine kinase pp56lck by the leukocyte common antigen (CD45). Oncogene 5:809
33. lck. J. Exp. Med. 172:347.
34. Schraven, B., Schoenhaut, D., Bruyns, E., Koretzky, G., Eckerskorn, C., Wallich, R., Kirchgessner, H., Sakorafas, P., Labkovsky, B., Ratnofsky, S. and Meuer, S. 1994. LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes. J. Biol. Chem. 269:29102.
35. Bruyns, E., Hendricks-Taylor, L. R., Meuer, S., Koretzky, G. A. and Schraven, B. 1995. Identification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45. J. Biol. Chem. 270:31372.
36. Cahir McFarland, E. D. and Thomas, M. L. 1995. CD45 protein-tyrosine phosphatase associates with the WW domain-containing protein, CD45-AP, through the transmembrane region. J. Biol. Chem. 270:28103.
37. Kitamura, K., Maiti, A., Ng, D. H. W., Johnson, P., Maizel, A. L. and Takeda, A. 1995. Characterization of the interaction between CD45 and CD45-AP. J. Biol. Chem. 270:21151.
38. Meyer, J., Nick, S., Stamminger, T., Grummt, F., Jahn, G. and Lipps, H. J. 1993. Inhibition of HIV-1 replication by a high-copy-number vector expressing antisense RNA for reverse transcriptase. Gene 129:263.
39. Ennis, P. D., Zemmour, J., Salter, R. D. and Parham, P. 1990. Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification. Proc. Natl Acad. Sci. USA 87:2833.
40. Mizushima, S. and Nagata, S. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:5322.
41. Schraven, B., Roux, M., Hutmacher, B. and Meuer, S. C. 1989. Triggering of the alternative pathway of human T cell activation involves members of the T200 family of glycoproteins. Eur. J. Immunol. 19:397.
42. Schraven, B., Samstag, Y., Altevogt, P. and Meuer, S. C. 1990. Association of CD2 and CD45 on human T lymphocytes. Nature 345:71.
43. Takeda, A., Wu, J. J. and Maizel, A. L. 1992. Evidence for monomeric and dimeric forms of CD45 associated with a 30-kDa phosphorylated protein. J. Biol. Chem. 267:16651.
44. Ross, S. E., Schraven, B., Goldman, F. D., Crabtree, J. and Koretzky, G. A. 1994. The association between CD45 and lck does not require CD4 or CD8 and is independent of T cell receptor stimulation. Biochem. Biophys. Res. Commun. 198:88.
45. Takeda, A., Maizel, A. L., Kitamura, K., Ohta, T. and Kimura, S. 1994. Molecular cloning of the CD45-associated 30-kDa protein. J. Biol. Chem. 269:2357.
46. Schraven, B., Ratnofsky, S., Gaumont, Y., Lindegger, H., Kirchgessner, H., Bruyns, E., Moebius, U. and Meuer, S. C. 1994. Identification of a novel dimeric phosphoprotein (pp29/30) associated with signaling receptors in human T lymphocytes and natural killer cells. J. Exp. Med. 180:897.