Whole body protein metabolism in human pulmonary tuberculosis and undernutrition: Evidence for anabolic block in tuberculosis

Clinical Science

Volumn 94, Issue 3, 1998, Pages 321-331

  Macallan, Derek C ^a   McNurlan, Margaret A ^b   Kurpad, Anura V ^c   De Souza, George ^c   Shetty, Prakash S ^c   Calder, A Graham ^d   Griffin, George E ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b STONY BROOK UNIVERSITY   (United States)

^c ST JOHN'S NATIONAL ACADEMY OF HEALTH SCIENCES   (India)

^d ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Cachexia; Malnutrition; Protein metabolism; Tuberculosis; Undernutrition; Wasting

Indexed keywords

CARBON 13; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; LEUCINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD GAS ANALYSIS; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENERGY EXPENDITURE; ENERGY METABOLISM; FEMALE; HUMAN; ISOTOPE LABELING; LUNG TUBERCULOSIS; MALE; MALNUTRITION; NUTRITIONAL SUPPORT; OXIDATION; PRIORITY JOURNAL; PROTEIN METABOLISM; WASTING SYNDROME;

EID: 0031930883     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0940321     Document Type: Article

References (41)

1. Cuthbertson DP. Observations on disturbance of metabolism produced by injury to the limbs. Quart J Med 1932; 1: 233-46.
2. Waterlow JC. Protein turnover with special reference to man. J Exp Physiol 1984; 69: 409-38.
3. Scares MJ, Piers LS, Shetty PS, Robinson S, Jackson AA, Waterlow JC. Basal metabolic rate, body composition and whole-body protein turnover in Indian men with differing nutritional status. Clin Sci 1991: 81: 419-25.
4. Scares MJ, Piers LS, Shetty PS, Jackson AA, Waterlow JC. Whole body protein turnover in chronically undernourished individuals. Clin Sci 1994; 86: 441-6.
5. Long CL, Jeevanandam M, Kim BM, Kinney JM. Whole body protein synthesis and catabolism in septic man. Am J Clin Nutr 1977; 30: 1340-4.
6. Morton RE, Hutchings J, Halliday D, Rennie MJ, Wolman SL. Protein metabolism during treatment of chest infection in patients with cystic fibrosis. Am J Clin Nutr 1988; 47: 214-19.
7. Macallan DC, McNurlan MA, Milne E, Calder AG, Garlick PJ, Griffin GE. Whole body protein turnover from leucine kinetics and the response to nutrition in Human Immunodeficiency Virus infection. Am J Clin Nutr 1995; 61: 818-26.
8. Paton NIJ, Angus B, Simpson A, et al Protein metabolism in melioidosis. Transactions of the Royal Society of Tropical Medicine and Hygiene 1997; 91: 500.
9. Tomkins AM, Garlick PJ, Schofield WN, Waterlow JC. The combined effects of infection and malnutrition on protein metabolism in children. Clin Sci 1983; 65: 313-24.
10. Garlick PJ, McNurlan MA, Fern EB, Tomkins AM, Waterlow JC. Stimulation of protein synthesis and breakdown by vaccination. Br Med J 1980; 281: 263-5.
11. Kien CL, Young VR, Rohrbaugh DK, Burke JF. Increased rates of whole body protein synthesis and breakdown in children recovering from burns. Ann Surg 1978; 187: 383-91.
12. 14C]-leucine. Surgery 1980; 88: 294-300.
13. 15N]-alanine. Am J Physiol 1981; 241: E64-71.
14. Melville S, McNurlan MA, Calder AG, Garlick PJ. Increased protein turnover despite normal energy metabolism and responses to feeding in patients with lung cancer. Cancer Res 1990; 50: 1125-31.
15. Jeevanandam M, Horowitz GD, Lowry SF, Brennan MF. Cancer cachexia and protein metabolism. Lancet 1984; 2: 1423-6.
16. Streat SJ, Beddoe AH, Hill GL. Aggressive nutritional support does not prevent protein loss despite fat gain in septic intensive care patients. J Trauma 1987; 27: 262-6.
17. Ash SA, Griffin GE. Effect of parenteral nutrition on protein turnover in endotoxaemic rats. Clin Sci 1989; 76: 659-66.
18. Kotler DP, Tierney AR, Culpepper-Morgan JA, Wang J, Pierson RN. Effect of home total parenteral nutrition on body composition in patients with Acquired Immunodeficiency Syndrome. J Parenteral Enteral Nutr 1990; 14: 454-8.
19. The World Health Report 1995: Bridging the gaps. World Health Forum, 1995; 16:377-385.
20. Lucas SB, De Cock KM, Hounnou A, et al. Contribution of tuberculosis to slim disease in Africa. Br Med J 1994; 308: 1531-3.
21. Eskandari MK, Nguyen DT, Kunkel SL, Remick DG. WEHI 164 subclone 13 assay for TNF: sensitivity, specificity and reliability. Immunol Invest 1990; 19: 69-79.
22. Aarden LA, DeGrott ET, Schaap IL, Lansdrop PM. Production of hybridoma growth factor by human monocytes. Eur J Immund 1987; 17: 1411-16.
23. DeForge LE, Remick DG. Sandwich ELISA for detection of picogram quantities of interleukin-8. Immunol Invest 1991; 20: 89-97.
24. Harris JA, Benedict FG. A biometric study of basal metabolism in man. Washington DC: Camegie Institute Publication No. 279, 1919.
25. Schofield WN. Predicting basal metabolic rate, new standards and review of previous work. Hum Nutr Clin Nutr 1985; 39C (Suppl. I): 5-41.
26. 13C leucine infusion. Metabolism 1989; 38: 248-55.
27. Garlick PJ, McNurlan MA, McHardy KC, et al. Rates of nutrient utilization in man measured by combined respiratory gas analysis and stable isotopic labelling: effect of food intake. Hum Nutr: Clin Nutr 1987; 41C: 177-91.
28. 15N]urea. Am J Clin Nutr 1994; 59: 1000-11.
29. El-Khoury AE, Sanchez M, Fukagawa NK, Gleason RE, Tsay RH, Young VR The 24-h kinetics of leucine oxidation in healthy adults receiving a generous leucine intake via three discrete meals. Am J Clin Nutr 1995; 62: 579-90.
30. 2 technique vs. plasma precursor approach. Am J Physiol 1995; 268: E174-84.
31. Durnin JVGA, Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974; 32: 77-97.
32. Garlick PJ. Evaluation of the formulae for calculating nutrient utilization rates from respiratory gas measurements in fed subjects. Hum Nutr: Clin Nutr 1987; 41C: 165-76.
33. Macallan DC, Cook EB, Preedy VR, Griffin GE. The effect of endotoxin on rat skeletal muscle protein gene expression, Int J Biochem Cell Biol 1996; 28: 511-20.
34. Macallan DC, Griffin GE. Cardiac muscle protein gene expression in the endotoxin-treated rat Clin Sci 1994; 87: 539-46.
35. Hommes MJT, Romijn JA, Endert E, Schattenkerk JKME, Sauerwein HP. Insulin sensitivity and insulin clearance in Human Immunodeficiency Virus-infected men. Metabolism 1991; 40: 651-6.
36. Klausner JD, Makonkawkeyoon S, Akarasewi P, et al. The effect of thalidomide on the pathogenesis of Human Immunodeficiency Virus type I and M. tuberculosis infection. J Acquired Immune Defic Syndr Human Retrovir 1996; 11: 247-57.
37. Sharma RJ, Macallan DC, Sedgwick P, Remick DG, Griffin GE. Kinetics of endotoxin induced acute phase protein gene expression in liver and its modulation by monoclonal antibody to TNF-α in the rat. Am J Physiol 1992; 262: R786-93.
38. Hommes MJT, Romijn JA, Endert E, Schattenkerk JKME, Sauerwein HP. Basal fuel homeostasis in symptomatic human immunodeficiency virus infection. Clin Sci 1991; 80: 359-65.
39. Alvarez C, Ramos A. Lipids, lipoproteins, and apoproteins in serum during infection, Clin Chem 1986; 32: 142-5.
40. Hardardottir I, Grunfeld C, Feingold KR. Effects of endotoxin and cytokines on lipid metabolism. Curr Opin Lipidol 1994; 5: 207-15.
41. Wolfe RR Shaw JHF, Durkot MJ. Effect of sepsis on VLDL kinetics: responses in basal state and during glucose infusion. Am J Physiol 1985; 248: E732-40.