Decreased circulating levels of vitamin K and 25-hydroxyvitamin D in osteopenic elderly men

Metabolism: Clinical and Experimental

Volumn 47, Issue 2, 1998, Pages 195-199

  Tamatani, Michio ^b   Morimoto, Shigeto ^a   Nakajima, Masayoshi ^b   Fukuo, Keisuke ^b   Onishi, Toshio ^b   Kitano, Shoichi ^b   Niinobu, Tadaaki ^b   Ogihara, Toshio ^b  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; ALBUMIN; FARNOQUINONE; MENAQUINONE; MENAQUINONE 7; PHYTOMENADIONE; TESTOSTERONE; UNCLASSIFIED DRUG; VITAMIN D;

ADULT; AGED; ARTICLE; BONE DENSITY; BONE MINERAL; DUAL ENERGY X RAY ABSORPTIOMETRY; ELDERLY CARE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; NORMAL HUMAN; OSTEOPENIA; PRIORITY JOURNAL; SCORING SYSTEM; VITAMIN BLOOD LEVEL; VITAMIN D METABOLISM;

EID: 0031930708     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(98)90220-7     Document Type: Article

References (44)

1. Cummings SR, Kelsey JL, Nrvitt MC, et al: Epidemiology of osteoporosis and osteoporotic fractures. Epidemiol Rev 7:178-208, 1985
2. Nordin BEC, Crilly RG, Smith DA: Osteoporosis, in Nordin BEC (ed): Metabolic Bone and Stone Disease (ed 2). Edinburgh, UK, Churchill Livingstone, 1984, pp 1-70
3. Riggs BL, Melton LJ III: Involutional osteoporosis. N Engl J Med 314:1676-1684, 1986
4. Aloia J, Cohn S, Vaswani AN, et al: Risk factors for postmenopausal osteoporosis. Am J Med 78:95-100, 1985
5. Price PA, Williamson MK, Lothringer JW: Origin of the vitamin K-dependent bone protein found in plasma and its clearance by kidney and bone. J Biol Chem 256:12760-12766, 1981
6. Hauschka PV, Lian JB, Gallop PM: Direct identification of the calcium-binding amino acid, γ-carboxyglutamate, in mineralized tissue. Proc Natl Acad Sci USA 72:3925-3929, 1975
7. 1 in osteoporosis. J Clin Endocrinol Metab 60:1268-1269, 1985
8. 2 are decreased in elderly women with hip fracture. J Bone Miner Res 10:1241-1245, 1993
9. Hodges SJ, Pilkington MJ, Stamp TCB, et al: Depressed levels of circulating menaquinones in patients with osteoporotic fractures of the spine and femoral neck. Bone 12:387-389, 1991
10. Meier DE, Orwell ES, Jones JM: Marked disparity between trabecular and cortical bone loss with age in healthy men: Measurement by vertebral computed tomography and radial photon absorptiometry. Ann Intern Med 101:605-612, 1984
11. Orwell ES, Oviatt SK, McClung MR, et al: The rate of bone mineral loss in normal men and the effects of calcium and cholecalciferol supplementation. Ann Intern Med 112:29-34, 1990
12. Thomas RK: A methodological critique of the 'ideal weight' concept. JAMA 250:506-510, 1983
13. Sbimotsuji Y, Seino Y: Competitive protein binding assay for 25-hydroxycholecalciferol. Methods Enzymol 67:466-472, 1980
14. Lee S, Morimoto S, Onishi T, et al: Normal serum 1,25-dihydroxyvitamin D in patients with medullary carcinoma of the thyroid. J Clin Endocrinol Metab 55:361-363, 1982
15. 1 epoxide in human plasma with electrofluorimetric reaction detection. J Chromatogr 289:377-385, 1984
16. Laska DJ, Suttie JW: Location of gamma-carboxyglutamyl residues in partially carboxylated prothrombin preparations. Biochemistry 27:8636-8641, 1988
17. Payne RB, Little AJ, Williams RB, et al: Interpretation of serum calcium in patients with abnormal serum proteins. Br Med J 4:643-646, 1973
18. Shiraki M, Fukunaga M, Monta R, et al: Cross calibrated values of vertebral bone mineral density in Japanese. J Bone Miner Metab 9:44-49, 1991 (suppl)
19. Tremollieres FA, Pouilles JM, Ribot C: Vertebral postmenopausal bone loss is reduced in overweight women: A longitudinal study in 155 early postmenopausal women. J Clin Endocrinol Metab 77:683-686, 1993
20. Jackson JA, Spiekerman AM: Testosterone deficiency is common in men with hip fracture after simple falls. Clin Res 37:131A, 1989 (abstr)
21. Resch H, Pietschmann P, Woloszczuk W, et al: Bone mass and biochemical parameters of bone metabolism in men with spinal osteoporosis. Eur J Clin Invest 22:542-545, 1992
22. Vermeulen A, Kaufman JM, Giagulli VA: Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males. J Clin Endocrinol Metab 81:1821-1826, 1996
23. Shino M: Determination of endogenous vitamin K (phylloquinone and menaquinone-n) in plasma by high-performance liquid chromatography using platinum oxide catalyst reduction and fluorescence detection. Analyst 113:393-397, 1988
24. Sadowski JA, Hood SJ, Dallai GE, et al: Phylloquinone in plasma from elderly and young adults: Factors influencing its concentration. Am J Clin Nutr 50:100-108, 1989
25. Delvin EE, Glovieux FH, Dussault M, et al: Simultaneous measurement of serum 25-hydroxycholecalciferol and 25-hydroxyergocalciferol. Med Biol 57:165-170, 1979
26. Orwoll ES, Weigel RM, Oviatt SK, et al: Serum protein concentrations and bone mineral content in aging normal men. Am J Clin Nutr 46:614-621, 1987
27. 2, menaquinone-7 and menaquinone-8. Clin Sci 78:63-66, 1990
28. Wootton R, Brereton PJ, Clark MB, et al: Fractured neck of femur in the elderly: An attempt to identify patients at risk. Clin Sci 57:93-101, 1979
29. Orwell ES, Meier DE: Alterations in calcium, vitamin D, and parathyroid hormone physiology in normal men with aging: Relationship to the development of senile osteopenia. J Clin Endocrinol Metab 63:1262-1269, 1986
30. Sherman SS, Hollis BW, Tobin JD: Vitamin D status and related parameters in a healthy population: The effects of age, sex, and season. J Clin Endocrinol Metab 71:405-413, 1990
31. MacLaughlin J, Holick MF: Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest 76:1536-1538, 1985
32. Omdahl JL, Garry PJ, Hunsaker LA, et al: Nutritional status in a healthy elderly population: Vitamin D. Am J Clin Nutr 36:1225-1233, 1982
33. Lukert BP, Carey M, McCarty B, et al: Influence of nutritional factors on calcium-regulating hormones and bone loss. Calcif Tissue Int 40:119-125, 1987
34. Lips P, van Ginkel FC, Jongen MJM, et al: Determinants of vitamin D status in patients with hip fracture and in elderly control subjects. Am J Clin Nutr 46:1005-1010, 1987
35. Norman AW, Henry HL: Vitamin D: Metabolism and mechanism of action, in Favus MJ (ed): Primer on The Metabolic Bone Diseases and Disorders of Mineral Metabolism (ed 2). New York, NY, Raven, 1993, pp 63-70
36. Nordin BEC, Morris HA: Osteoporosis and vitamin D. J Cell Biochem 49:19-25, 1992
37. Hruska KA, Rolnick F: Hyperphosphatemia and hypophosphatemia, in Favus MJ (ed): Primer on The Metabolic Bone Diseases and Disorders of Mineral Metabolism (ed 2). New York, NY, Raven, 1993, pp 213-219
38. Lian J, Stewart C, Puchacz E, et al: Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression. Proc Natl Acad Sci USA 86:1143-1147, 1989
39. Hara K, Akiyama Y, Tajima T, et al: Menatetrenone inhibits bone resorption partly through inhibition of PGE2 synthesis in vitro. J Bone Miner Res 8:535-542, 1993
40. Knapen MH, Hamulyak K, Vermeer C: The effect of vitamin K on circulating osteocalcin (bone Gla protein) and urinary calcium excretion. Ann Intern Med 111:1001-1005, 1989
41. Plantalech L, Guillaumont M, Vergnaud P, et al: Impairment of gamma carboxylation of circulating osteocalcin (bone Gla protein) in elderly women. J Bone Miner Res 6:1211-1216, 1991
42. Vanderschueren D, Gevers G, Raymaekers G, et al: Sex- and age-related changes in bone and serum osteocalcin. Calcif Tissue Int 46:179-182, 1990
43. Shearer MJ: Vitamin K. Lancet 345:229-234, 1995
44. Conly JM, Stein K: Quantitative and qualitative measurements of K vitamins in human intestinal contents. Am J Gastroenterol 87:311-316, 1992