Primary defect in CD8+ lymphocytes in the antibody deficiency disease (common variable immunodeficiency): Abnormalities in intracellular production of interferon-gamma (IFN-γ) in CD28+ ('cytotoxic') and CD28- ('suppressor') CD8+ subsets

Clinical and Experimental Immunology

Volumn 111, Issue 1, 1998, Pages 70-75

  North, M E ^a   Webster, A D B ^a   Farrant, J ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

CD28; CD8+ cells; Common variable immunodeficiency; Interferon gamma; Subsets of CD8+ cells; T cell activation

Indexed keywords

CD28 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMORAL IMMUNE DEFICIENCY; MALE; PRIORITY JOURNAL; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGED; ANTIGENS, CD28; ANTIGENS, CD8; COMMON VARIABLE IMMUNODEFICIENCY; CYTOKINES; FEMALE; HUMANS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; T-LYMPHOCYTE SUBSETS;

EID: 0031929970     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00479.x     Document Type: Article

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