Testicular plasmacytoma following chemical orchiectomy: Potential role of hypogonadism in myeloma proliferation

Leukemia and Lymphoma

Volumn 28, Issue 3-4, 1998, Pages 437-442

  Kahr, Walter H ^a   Al Homadhi, Aziz ^a   Meharchand, Jacinta ^a   Bailey, Dennis J ^a   Stewart, A Keith ^a  

^a TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Androgen deficient state; B cell development; Multiple myeloma; Orchiectomy; Plasmacytoma; Sex hormones; Sex steroids

Indexed keywords

ANDROGEN; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; FLUOXYMESTERONE; GOSERELIN; LEUPRORELIN; MELPHALAN; VINCRISTINE;

ADULT; ADVERSE DRUG REACTION; ARTICLE; CASE REPORT; HUMAN; HYPOGONADISM; MALE; MULTIPLE MYELOMA; ORCHIECTOMY; PLASMACYTOMA; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; STEM CELL TRANSPLANTATION;

ADENOCARCINOMA; B-LYMPHOCYTES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; HYPOGONADISM; LEUKOPOIESIS; MALE; MIDDLE AGED; MULTIPLE MYELOMA; ORCHIECTOMY; PLASMACYTOMA; PROSTATIC NEOPLASMS; TESTICULAR NEOPLASMS; TESTOSTERONE; TRANSPLANTATION, AUTOLOGOUS;

EID: 0031929508     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Kincade, P. W., Medina, K. L., Smithson, G. and Scott, D. C. (1994). Pregnancy: a clue to normal regulation of B-lymphopoiesis. Immunol. Today, 15, 539-544.
2. Kincade, P. W., Medina, K. L. and Smithson. G. (1994). Sex hormones as negative regulators of lymphopoiesis. Immunological Rev., 137, 119-134.
3. Wiltshaw, E. (1976). The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of the bone and myelomatosis. Medicine, 55, 217-238.
4. Levin, H. S. and Mostofi, F. K. (1970). Symptomatic plasmacytoma of the testis. Cancer, 25, 1193-1203.
5. Young, R. H. and Scully, R. E. (1990). In: Hematopoietic and Metastatic Tumors, pp. 151-161. (American Society of Clinical Pathologists, Chicago.)
6. Young, R. H. and Scully, R. E. (1986). In: Miscellaneous Neoplasms and Nonneoplastic Lesions (eds.) Talerman. A. and Roth, L. M. pp. 93-129. (Churchill Livingstone, New York.)
7. Chica, G., Johnson, D. E. and Ayala, A. G. (1978). Plasmacytoma of testis presenting as primary tumor. Urology, 11, 90-92.
8. Ishii, K., Yamato, K., Kubonishi, I., Taguchi, H., Ohtsuki, Y. and Miyoshi, I. (1992). IgD myeloma presenting as a testicular tumor: Establishment and characterization of an IgD-secreting myeloma cell line. Am. J. Hematoi, 41, 218-224.
9. Oppenheim, P. I., Cohen, S. and Anders, K. H. (1991). Testicular plasmacytoma. Arch. Pathol. Lab. Med., 115, 629-632.
10. Osman, R. and Morrow, J. W. (1966). Myeloma of the testicle: A case report. J. Urol, 96, 352-355.
11. Soumerai, S. and Gleason, E. A. (1980). Asynchronous plasmacytoma of the stomach and testis. Cancer, 45, 396-400.
12. Steinberg, D. (1975). Plasmacytoma of the testes. Cancer, 36, 1470-1472.
13. Taylor, R. E., Duncan, W. and Parker, A. C. (1986). Case Report: Bilateral testicular plasmacytoma. Clin. Radiol., 37, 293-294.
14. Brambilla, P. G., Assi, A., Ballarati, E., Turri, E., Zaroli. A. and Montalbetti, L. (1993). Plasmacytoma of the testis. Min. Medica, 84, 211-215.
15. Kang, M. J., Kim, T. Y., Bang, Y. J., Heo, D. S., Park, S., Kim, B. K., Kim, N. K. and Kim, C. W. (1994). Multiple myeloma presenting as a testicular mass. Kor. J. Intern. Med., 9, 39-42.
16. Talerman, A. (1982). In: Mesenchymal tumors and malignant Iymphoma of the ovary, ed. Blaustein, A. pp. 578-579. (Springer-Verlag NY Inc, New York.)
17. Ikuta, K., Uchida, N., Friedman, J. and Weissman, I. L. (1992). Lymphocyte development from stem cells. Annu. Rev. Immunol., 10, 759-783.
18. Wilson, C. A., Mrose, S. A. and Thomas, D. W. (1995). Enhanced production of B-lymphocytes after castration. Blood, 85, 1535-1539.
19. Bagby, G. C. and Segal, G. M. (1995). In: Growth Factors and the Control of Hemalopoiesis, eds. Hoffman, R., Benz, E. J., Shattil, S. J., Furie, B., Cohen, H. J. & Silberstein, L. E. pp. 207-241. (Churchill Livingstone, New York.)
20. Suematsu, S., Matsuda, T., Aozasa, K., Akira, S., Nakano, N. and Ohno, S. (1989). IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc. Natl. Acad. Sci. U.S.A., 86, 7547-7551.
21. Namen, A. E., Lupton, S., Hjerrild, K., Wignall, J., Mochizuki, D. Y., Schmierer, A., Mosley, B., March, C. J., Urdal, D., Gillis, S., Cosman, D. and Goodwin, R. G. (1988). Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature, 333, 571-573.
22. Morrissey, P. J., Conlon, P., Charrier, K., Braddy, S., Alpert, A., Williams, D., Namen, A. E. and Mochizuki, D. (1991). Administration of IL-7 to normal mice stimulates B-lymphopoiesis and peripheral lymphadenopathy. J. Immunol., 147, 561-568.
23. Grabstein, K. H., Waldschmidt, T. J., Finkelman, F. D., Hess, B. W., Alpert, A. R., Boiani, N. E., Namen, A. E. and Morrissey, P. J. (1993). Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody. J. Exp. Med., 178, 257-264.
24. Sudo, T., Nishikawa, S., Ohno, N., Akiyama, N., Tamakoshi, M., Yoshida, H. and Nishikawa, S.-I. (1993). Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc. Natl. Acad. Sci. USA, 90, 9125-9129.
25. Medina, K. L. and Kincade, P. W. (1994). Pregnancy-related steroids are potential negative regulators of B-lymphopoiesis. Proc. Natl. Acad. Sci. U.S.A., 91, 5382-5386.
26. Thompson, E. J. (1981). The effect of estradiol upon the thymus of the sexually immature female mouse. J. Steroid Biochem., 14, 167-174.
27. Mase, Y. and Oishi, T. (1991). Effects of castration and testosterone treatment on the development and involution of the Bursa of Fabricius and the thymus in the Japanese quail. Gen. Comp. Endocrinol., 84, 426-433.
28. Le Douarin, N. M., Michel, G. and Baulieu, E.-E. (1980). Studies of testosterone-induced involution of the Bursa of Fabricius. Dev. Biol., 75, 288-302.
29. Medina, K. L., Smithson, G. and Kincade, P. W. (1993). Suppression of B-lymphopoiesis during normal pregnancy. J. Exp. Med., 178, 1507-1515.
30. Smithson, G., Medina, K., Ponting, I. and Kincade, P. W. (1995). Estrogen suppresses stromal cell-dependent lymphopoiesis in culture. J. Immunol., 155, 3409-3417.
31. Tabibzadeh, S. S., Santhanam, U., Sehgal, P. B. and May, L. T. (1989). Cytokine-induced production of IFN-beta 2/IL-6 by freshly explanted human endometrial stromal cells. Modulation by estradiol-17 beta. J. Immunol., 142, 3134-3139.
32. Bellido, T., Jilka, R. L., Boyce, B. F., Girasole, G., Broxmeyer, H., Dalrymple, S. A., Murray, R. and Manolagas, S. C. (1995). Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. J. Clin. Invest., 95, 2886-2895.
33. Passeri, G., Girasole, G., Jilka, R. L. and Manolagas, S. C. (1993). Increased interleukin-6 production by murine bone marrow and bone cells after estrogen withdrawal. Endocrinol., 133, 822-828.
34. Weinstein, Y. and Berkovich, Z. (1981). Testosterone effect on bone marrow, thymus, and suppressor T-cells in the (NZB X NZW)F1 mice: Its relevance to autoimmunity. J. Immunol., 126, 998-1002.
35. Garland, J. M., Lanotte, M. and Dexter, T. M. (1982). Expression of 20 alpha-hydroxysteroid dehydrogenase in non-lymphoid hemopoietic cell lines. Eur. J. Immunol, 12, 332-336.
36. Greenstein, B. D., Fitzpatrick, F. T. A., Adcock, I. M., Kendall, M. D. and Wheeler, M. J. (1986). Reappearance of the thymus in old rats after orchidectomy: inhibition of regeneration by testosterone. J. Endocrinol., 110, 417-422.
37. Olsen, N. J., Viselli, S. M., Shults, K., Stelzer, G. and Kovacs, W. J. (1994). Induction of immature thymocyte proliferation after castration of normal male mice. Endocrinology, 134, 107-113.
38. Greenstein, B. D., Fitzpatrick, F. T. A., Kendall, M. D. and Wheeler, M. J. (1987). Regeneration of the thymus in old male rats treated with a stable analogue of LHRH. J. Endocrinol., 112, 345-350.
39. Marchetti, B., Guarcello, V., Morale, M. C., Bartoloni, G., Raiti, F., Palumbo, G. J., Farinella, Z., Cordaro, S. and Scapagnini, U. (1989). Luteinizing hormone-releasing hormone (LHRH) agonist restoration of age-associated decline of thymus weight, thymic LHRH receptors, and thymocyte proliferative capacity. Endocrinology, 125, 1037-1045.
40. Blacker, C. M., Ataya, K. M., Savoy-Moore, R. T., Subramanian, M. G., Mutchnick, M. G. and Dunbar, J. C. (1991). The gonadotropin-releasing hormone agonist leuprolide affects the thymus and other non-reproductive systems of female rats. Acta Endocrinol., 125, 581-589.
41. Greenstein, B. D., de Bridges, E. F. and Fitzpatrick, F. T. (1992). Aromatase inhibitors regenerate the thymus in aging male rats. Int. J. Immunopharm., 14, 541-553.
42. Danel, L., Vincent, C, Rousset, F., Klein, B., Bataille, R., Flacher, M., Durie, B. G. and Revillard, J. P. (1988). Estrogen and progesterone receptors in some human myeloma cell lines and murine hybridomas. 30, 363-367.
43. Gray, A., Feldman, H. A., McKinlay, J. B. and Longcope, C. (1991). Age, disease, and changing sex hormone levels in middle-aged men: Results of the Massachusetts male aging study. J. Clin. Endocrinol. Metab., 73, 1016-1025.
44. Everaus, H., Hein, M. and Zilmer, K. (1993). Possible imbalance of the immuno-hormonal axis in multiple myeloma. Leukemia & Lymphoma, 11, 453-458.