Evaluation of urinary biomarkers for radical-induced liver damage in rats treated with carbon tetrachloride

Toxicology and Applied Pharmacology

Volumn 148, Issue 1, 1998, Pages 71-82

  De Zwart, Loeckie L ^a   Hermanns, Ralph C A ^b   Meerman, John H N ^b   Commandeur, Jan N M ^a   Salemink, Paul J M ^c   Vermeulen, Nico P E ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c NV ORGANON   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; CARBON TETRACHLORIDE; COPROPORPHYRIN; FREE RADICAL; LIPID PEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL PARAMETERS; CONTROLLED STUDY; EVALUATION AND FOLLOW UP; EXCRETION; LIVER INJURY; LIVER TOXICITY; MALE; NONHUMAN; RAT; URINARY EXCRETION; URINE LEVEL;

EID: 0031929366     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1997.8310     Document Type: Article

References (55)

1. Akubue P. I., Stohs S. J. Effect of alachlor on the urinary excretion of malondialdehyde, formaldehyde, acetaldehyde, and acetone by rats. Bull. Environ. Contam. Toxicol. 50:1993;565-571.
2. Ames B. N., Saul R. Genetic Toxicology of Environmental Chemicals. 1985;Liss, New York. p. 1-16.
3. Aruoma O. I., Halliwell B., Gajewski E., Dizdarogly M. Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide. Biochem. J. 272:1991;601-604.
4. Bagchi D., Bagchi M., Hassoun E., Stohs S. J. Endrin-induced urinary excretion of formaldehyde, acetaldehyde, malondialdehyde and acetone in rats. Toxicol. 75:1992;81-89.
5. Bagchi D., Bagchi M., Hassoun E., Stohs S. J. Carbon-tetrachloride-induced urinary excretion of formaldehyde, malondialdehyde, acetaldehyde and acetone in rats. Pharmacology. 47:1993b;209-216.
6. Bagchi D., Shara M. A., Bagchi M., Hassoun A., Stohs J. Time-dependent effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on serum and urine levels of malondialdehyde, formaldehyde, acetaldehyde, and acetone in rats. Toxicol. Appl. Pharmacol. 123:1993a;83-88.
7. Bai C.-L., Canfield P. J., Stacey N. H. Individual serum bile acids as early indicators of carbon tetrachloride- and chloroform-induced liver injury. Toxicol. 75:1992;221-234.
8. Benedetti A., Casini A. F., Ferrali M., Comporti M. Effects of diffusible products of peroxidation of rat liver micorsomal lipids. Biochem. J. 180:1979;303-312.
9. Blair P. C., Thompson M. B., Wilson R. E., Esber H. H., Maronpot R. R. Correlation of changes in serum analytes and hepatic histopathology in rats exposed to carbon tetrachloride. Toxicol. Lett. 55:1991;149-159.
10. Burnham B. F., Bachman R. C. Enzymatic syntheses of porphyrins. The Porphyrins. 1979;Academic Press, New York. p. 233-256.
11. Comporti M. Three models of free radical induced cell injury. Chem.-Biol. Interact. 72:1989;1-56.
12. Cundy K. C., Kohen R., Ames B. N. Determination of 8-hydroxyguanosine in human urine: a possible assay forin vivo. Basic Life Sci. 49:1988;479-482.
13. De Matteis F. Role of iron in the hydrogen peroxide-dependent oxidation of hexahydroporphyrins (porphyrinogens): A possible mechansim for the exacerbation by iron of hepatic uroporphyria. Mol. Pharmacol. 33:1988;261-266.
14. De Zwart L. L., Venhorst J., Groot M., Commandeur J. N. M., Hermanns R. C. A., Meerman J. H. M., Van Baar B. L. M., Vermeulen N. P. E. Simultaneous determination of eight lipid peroxidation degradation products in urine of rats treated with carbon tetrachloride using gas chromatography with electron-capture detection. J. Chromatogr. B. 694:1997;277-288.
15. Dohlman A. W., Black H. R., Royall J. A. Expired breath hydrogen peroxide is a marker of acute airway inflammation in pediatric patients with asthma. Am. Rev. Respir. Dis. 148:1993;955-960.
16. Esterbauer H. Aldehydic products of lipid peroxidation. McBrien D. C. H., Slater T. F. Free Radicals, Lipid Peroxidation and Cancer. 1982;101 Academic Press, London.
17. Esterbauer H., Schaur R. J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radical Biol. Med. 11:1991;81-128.
18. Floyd R. A., West M. S., Eneff K. L., Schneider J. E., Wong P. K., Tingey D. T., Hogsett W. E. Conditions influencing yield and analysis of 8-hydroxy-2′-deoxyguanosine in oxidatively damaged DNA. Anal. Biochem. 188:1990;155-158.
19. Fraga G. F., Shigenega M. K., Park J.-W., Degan P., Ames B. N. Oxidative damage to DNA during aging; 8-hydroxy-2′deoxyguanosine in rat organ DNA and urine. Proc. Natl. Acad. Sci. USA. 87:1990;4533-4537.
20. Ghiselli A., Laurenti O., De Mattia G., Maiani G., Ferro-Luzzi A. Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients. Free Radical Biol. Med. 13:1992;621-626.
21. Goeptar A. R., Scheerens H., Vermeulen N. P. E. Oxygen and xenobiotic reductase activities of cytochrome P450. Crit. Rev. Toxicol. 25:1995;25-65.
22. González A. P., de Toranzo E. G. D., Castro J. A. Depression of liver microsomal glucose 6-phosphatase activity in carbon tetrachloride-poisoned rats. Potential synergistic effects of lipid peroxidation and of covalent binding of haloalkane-derived free radicals to cellular components in the process. Free Radical Biol. Med. 21:1996;81-87.
23. Hageman J. J., Bast A., Vermeulen N. P. E. Monitoring of oxidative free radical damagein vivo. Chem.-Biol. Interact. 82:1992;243-293.
24. Halliwell B., Gutteridge J. M. Free Radicals in Biology and Medicine. 1989;Oxford Univ. Press (Clarendon), Oxford.
25. Halliwell B., Kaur H., Ingelman-Sundberg M. Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary note. Free Rad. Biol. Med. 10:1991;439-441.
26. 18. J. Labelled Comp. Radiopharmaceut. 34:1994;191-1971.
27. Hollstein M. C., Brooks P., Linn S., Ames B. N. Hydroxymethyluracil DNA glycosylase in mammalian cells. Proc. Natl. Acad. Sci. USA. 81:1984;4003-4007.
28. Jeejeebhoy K. N. In vivo. Free Rad. Biol. Med. 10:1991;191-193.
29. Kneepkens C. M. F., Lepage G., Roy C. C. The potential of the hydrocarbon breath test as a measure of lipid peroxidation. Free Rad. Biol. Med. 17:1994;127-160.
30. Marnett L. J., Burcham P. C. Endogenous DNA adducts: Potential and paradox. Chem. Res. Toxicol. 6:1993;771-785.
31. McCullagh P., Nelder J. A. Generalized Linear Models. 1989;Chapman and Hall, London.
32. Miller D. M., Woods J. S. Urinary porphyrins as biological indicators of oxidative stress in the kidney. Interaction of mercury and cephaloridine. Biochem. Pharmacol. 46:1993;2235-2241.
33. Mizrahi S., Dolberg L., Jacobsohn W. Z. Alteration in aminotransferase levels in rats after acute hepatic injury. Israel J. of Med. Sci. 23:1987;188-192.
34. Mouret J.-F., Polverelli M., Sarrazini F., Cadet J. Ionic and radical oxidations of DNA by hydrogen peroxide. Chem.-Biol. Interact. 77:1991;187-201.
35. 2. J. Clin. Invest. 90:1992;2502-2507.
36. Morrow J. D., Roberts L. J. II. The isoprostanes. Current knowledge and directions for future research. Biochem. Pharmacol. 51:1996;1-9.
37. Mukerji S. K., Pimstone N. R. Free radical mechanism of oxidation of uroporphyrinogen in the presence of ferrous iron. Arch. Biochem. Biophys. 281:1990;177-184.
38. Ozaki M., Masuda Y. Carbon tetrachloride-induced cell death in perfused livers from phenobarbital-pretreated rats under hypoxic conditions and various ionic milieu. Biochem. Pharmacol. 46:1993;2039-2049.
39. Pflaum M., Boiteux S., Epe B. Visible light generates oxidative DNA base modifications in high excess of strand breaks in mammalian cells. Carcinogenesis. 15:1994;297-300.
40. Poli G., Albano E., Dianzani M. U. The role of lipid peroxidation in liver damage. Chem. Phys. Lipids. 45:1987;117-142.
41. Recknagel R. O. A new direction in the study of carbon tetrachloride hepatotoxicity. Life Sci. 33:1983;401-408.
42. Recknagel R. O., Glende E. A. Jr., Dolak J. A., Waller R. L. Mechanism of carbon tetrachloride toxicity. Pharmacol. Ther. 43:1989;139-154.
43. Reinke L. A., Towner R. A., Janzen E. G. Spin trapping of free radical metabolites of carbon tetrachloridein vivoin vitro. Toxicol. Appl. Pharmacol. 112:1992;17-23.
44. SAS Institute Inc. 1993, SAS Institute Inc. Cary, NC.
45. Shigenaga M. K., Ames B. N. Assay for 8-hydroxy-2′-deoxyguanosine: A biomarker ofin vivo. Free Radical Biol. Med. 10:1991;211-216.
46. Shigenaga M. K., Gimeno C. J., Ames B. N. Urinary 8-hydroxy-2′-deoxyguanosine as a biological marker ofin vivo. Proc. Natl. Acad. Sci. USA. 86:1989;9697-9701.
47. Slater T. F. Free-radical mechanisms in tissue injury. Biochem. J. 222:1984;1-15.
48. Van den Goorbergh J. A. M., De Wit H., Tijdens R. B., Mulder G. J., Meerman J. H. N. Prevention by thioethers of the hepatotoxicity and covalent binding to macromolecules of N-hydroxy-2-acetylaminofluorene and its sulfate ester in rat liverin vivoin vitro. Carcinogenesis. 8:1987;275-279.
49. Van der Vliet A., Bast A. Effect of oxidative stress on receptors and signal transmission. Chem.-Biol. Interact. 85:1992.
50. Varma S. D., Devamanoharan P. S. Excretion of hydrogen peroxide in human urine. Free Radical Res. Commun. 8:1990;73-78.
51. Woods J. S. Regulation of porphyrin and heme metabolism in the kidney. Semin. Hematol. 25:1988;336-348.
52. Woods J. S. Altered porphyrin metabolism as a biomarker of mercury exposure and toxicity. Can. J. Physiol. Pharmacol. 74:1996;210-215.
53. Woods J. S., Calas C. A. Iron stimulation of free radical-mediated porphyrinogen oxidation by hepatic and renal mitochondria. Biochem. Biophys. Res. Commun. 160:1989;101-108.
54. Woods J. S., Miller H. A. Quantitative measurement of porphyrins in biological tissues and evaluation of tissue porphyrins during toxicant exposures. Fundam. Appl. Toxicol. 21:1993;291-297.
55. Yeo H. C., Helbock H. J., Chyu D. W., Ames B. N. Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry. Anal. Biochem. 220:1994;391-396.