Interactions between zinc and vitamin A: An update

American Journal of Clinical Nutrition

Volumn 68, Issue 2 SUPPL., 1998, Pages

  Christian, Parul ^a,b   West Jr , Keith P ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Division of Human Nutrition   (United States)

Author keywords

Alcohol dehydrogenase; Interactions; Liver function; Mechanisms; Retinol binding protein; Vitamin A; Zinc

Indexed keywords

ALCOHOL DEHYDROGENASE; RETINAL; RETINOL; RETINOL BINDING PROTEIN; ZINC;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; CHILD; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; HUMAN; INTESTINE ABSORPTION; LIVER FUNCTION; NONHUMAN; PROTEIN CALORIE MALNUTRITION; RETINOL DEFICIENCY; VITAMIN BLOOD LEVEL; ZINC BLOOD LEVEL; ZINC DEFICIENCY; ZINC METABOLISM;

ANIMALIA; UNIDENTIFIED AGENTS;

EID: 0031928779     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/68.2.435S     Document Type: Conference Paper

References (45)

1. Smith JC Jr. The vitamin A-zinc connection: a review. Ann N Y Acad Sci 1980;355:62-74.
2. Solomons NW, Russell RM. The interaction of vitamin A and zinc: implications for human nutrition. Am J Clin Nutr 1980;33:2031-40.
3. Mejia LA. Vitamin A-nutrient interrelationships. In: Bauernfeind JC, ed. Nutrition basics and applied science - a series of monographs. New York: Academic Press Inc, 1986:89-100.
4. Terhune MW, Sandstead HH. Decreased RNA polymerase activity in mammalian zinc deficiency. Science 1972;177:68-9.
5. Smith JE, Brown ED, Smith JC Jr. The effect of zinc deficiency on the metabolism of retinol binding protein in the rat. J Lab Clin Med 1974;84:692-7.
6. Smith JC Jr, Brown ED, McDaniel EG, Chan W. Alterations in vitamin A metabolism during zinc deficiency and food and growth restriction. J Nutr 1976;106:569-74.
7. Wald G. The interconversion of the retinenes and vitamin A in vitro. Biochem Biophys Acta 1950;4:215-28.
8. Huber AM, Gershoff SN. Effects of zinc deficiency on the oxidation of retinol and ethanol in rats. J Nutr 1975;105:1486-90.
9. Sundaresan PR, Cope FO, Smith JC Jr. Influence of zinc deficiency on retinal reductase and oxidase activities in rat liver and testes. J Nutr 1977;107:2189-97.
10. Mobarhan S, Greenberg B, Mehta R, Friedman H, Barch D. Zinc deficiency reduces hepatic cellular retinol-binding protein in rats. Int J Vit Nutr Res 1992;62:148-54.
11. Boron B, Hupert J, Barch DH, et al. Effect of zinc deficiency on hepatic enzymes regulating vitamin A status. J Nutr 1988;118:995-1001.
12. Ahn J, Koo SI. Effects of zinc and essential fatty acid deficiencies on the lymphatic absorption of vitamin A and secretion of phospholipids. J Nutr Biochem 1995;6:595-603.
13. Ahn J, Koo SI. Intraduodenal phosphatidycholine infusion restores the lymphatic absorption of vitamin A and oleic acid in zinc-deficient rats. J Nutr Biochem 1995;6:604-12.
14. Berzin NI, Bauman VK. Vitamin A-dependent zinc-binding protein and intestinal absorption of zinc in chicks. Br J Nutr 1987; 57:255-68.
15. Sklan D, Halevy O, Donoghue S. The effect of different dietary levels of vitamin A on metabolism of copper, iron and zinc in the chick. Int J Vitam Nutr Res 1987;57:11-8.
16. Duncan JR, Hurley LS. An interaction between zinc and vitamin A in pregnant and fetal rats. J Nutr 1978;108:1431-8.
17. Peters AJ, Keen CL, Lönnerdal B, Hurley LS. Zinc-vitamin A interaction in pregnant and fetal rats: supplemental vitamin A does not prevent zinc-deficiency-induced teratogenesis. J Nutr 1986;116: 1765-71.
18. Baly DL, Golub MS, Gershwin ME, Hurley LS. Studies of marginal zinc deprivation in rhesus monkeys. III. Effects on vitamin A metabolism. Am J Clin Nutr 1984;40:199-207.
19. Dorea JG, Olson JA. The rate of rhodopsin regeneration in the bleached eyes of zinc-deficient rats in the dark. J Nutr 1986; 116:121-7.
20. Kraft SP, Parker JA, Matuk Y, Venkatrao A. The rat electroretinogram in combined zinc and vitamin A deficiency. Invest Ophthalmol Vis Sci 1987;28:975-84.
21. Chase HP, Hambidge M, Barnett SE, Houts-Jacobs MJ, Lenz K, Gillespie J. Low vitamin A and zinc concentrations in Mexican-American migrant children with growth retardation. Am J Clin Nutr 1980;33:2346-9.
22. Hunt IF, Murphy NJ, Cleaver AE, et al. Zinc supplementation during pregnancy in low-income teenagers of Mexican descent: effects on selected blood constituents and on progress and outcome of pregnancy. Am J Clin Nutr 1985;42:815-28.
23. Kozlowski BW, Taylor ML, Baer MT, Blyler EM, Trahms C. Anti-convulsant medication use and circulating levels of total thyroxine, retinol binding protein, and vitamin A in children with delayed cognitive development. Am J Clin Nutr 1987;46:360-8.
24. Dorea JG. De Araújo MOG. Zinc and vitamin A in liver of fetuses and infants. Acta Pediatr Scand 1988;77:85-8.
25. Coutsoudis A, Coovadia HM, Broughton M, Salisbury RT, Elson I. Micronutrient utilization during measles treated with vitamin A or placebo. Int J Vitam Nutr Res 1991;61:199-204.
26. Ahmed F, Barua S, Mohiduzzaman M, et al. Interactions between growth and nutrient status in school-age children of urban Bangladesh. Am J Clin Nutr 1993;58:334-8.
27. Hustead VA, Greger JL, Gutcher GR. Zinc supplementation and plasma concentration of vitamin A in preterm infants. Am J Clin Nutr 1988;47:1017-21.
28. Marinho HA, Shrimpton R, Giugliano R, Burini RC. Influence of enteral parasites on the blood vitamin A levels in preschool children orally supplemented with retinol and/or zinc. Eur J Clin Nutr 1991;45:539-44.
29. Udomkesmalee E, Dhanamitta S, Sirisinha S, et al. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand. Am J Clin Nutr 1992;56:50-7.
30. Jalla S, Sazawal S, Black RE, Mazumder S, Sinha A, Bhan MK. Effect of zinc supplementation on anemia and vitamin A status in children. FASEB J 1997;11:A654 (abstr).
31. Parkinson CE, Tan JCY. Vitamin A concentration in amniotic fluid and maternal serum related to neural-tube defects. Br J Obstet Gynaecol 1982;89:935-9.
32. Sazawal S, Black RE, Bhan MK, Bhandari N, Sinha A, Jalla S. Zinc supplementation in young children with acute diarrhea in India. N Engl J Med 1995;333:839-44.
33. Shingwekar HG, Mohanram M, Reddy V. Effect of zinc supplementation on plasma levels of vitamin A and retinol-binding protein in malnourished children. Clin Chim Acta 1979;93:97-100.
34. Patek AJ, Haig C. The occurrence of abnormal dark adaptation and its relation to vitamin A metabolism in patients with cirrhosis of the liver. J Clin Invest 1939;18:609-16.
35. Russell RM, Morrison SA, Smith FR, Oaks EV, Carney EA. Vitamin A reversal of abnormal dark adaptation in cirrhosis. Ann Intern Med 1978;88:622-6.
36. Morrison SA, Russell RM, Carney EA, Oaks EV. Zinc deficiency: a cause of abnormal dark adaptation in cirrhotics. Am J Clin Nutr 1978;31:276-81.
37. McClain CJ, Van Thiel DH, Parker S, Badzin LK, Gilbert H. Alterations in zinc, vitamin A, and retinol-binding protein in chronic alcoholics. A possible mechanism for night blindness and hypogonadism. Alcohol Clin Exp Res 1979;3:135-41.
38. Abdu-Gusau K, Elegbede JA, Akanya O. Serum zinc, retinol and retinol-binding protein in levels in cirrhotics and hypogonadism. Eur J Clin Nutr 1989;43:53-7.
39. Atukorala TMS, Herath CA, Ramchandran S. Zinc and vitamin A status of alcoholics in a medical unit in Sri Lanka. Alcohol 1986;21:269-75.
40. Palin D, Underwood BA, Denning CR. The effect of oral zinc supplementation on plasma levels of vitamin A and retinol binding protein in cystic fibrosis. Am J Clin Nutr 1979;32:1253-9.
41. Navarro J, Desquilbet N. Depressed plasma vitamin A and retinol-binding protein in cystic fibrosis correlations with zinc deficiency. Am J Clin Nutr 1981;34:1439-40 (letter).
42. Underwood BA, Palin D. Reply to letter by Navarro and Desquilbet. Am J Clin Nutr 1981;34:1440 (letter).
43. Droódó M, Gierek T, Jendryczko A, Piekarska J. Pilch J, Polanska D. Zinc, vitamin A and E, and retinol-binding protein in sera of patients with cancer of the larynx. Neoplasma 1989;36:357-62.
44. Honkanen V, Knottinen YT, Mussalo-Rauhamaa H. Vitamins A and E, retinol binding protein and zinc in rheumatoid arthritis. Clin Exp Rheumatol 1989;7:465-9.
45. Sommer A, West KP Jr. Vitamin A deficiency: health, survival, and vision. New York: Oxford University Press, 1996.