The glutathione depleting agent diethylmaleate prolongs renal allograft survival

Journal of Surgical Research

Volumn 77, Issue 1, 1998, Pages 75-79

  Nathens, Avery B ^a   Rotstein, Ori D ^a   Jones, Julia J ^a   Dackiw, Alan P B ^a   Gorczynski, Reginald ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Allograft; Diethylmaleate; Glutathione; ICAM 1; Tolerance

Indexed keywords

CYCLOSPORIN A; GAMMA INTERFERON; GLUTATHIONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; MALEIC ACID DIETHYL ESTER; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; HELPER CELL; IMMUNOLOGICAL TOLERANCE; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY ALLOGRAFT; MALE; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION;

EID: 0031928397     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1998.5338     Document Type: Article

References (18)

1. Carlos, T. M., and Harlan, J. M. Leukocyte-endothelial adhesion molecules. Blood 84: 2068, 1994.
2. Kato, Y., Yamataka, A., Yagita, H., Okumura, K., Fujiwara, T., and Miyano, T. Specific acceptance of fetal bowel allograft in mice after combined treatment with anti-ICAM-1 and LFA-1 antibodies. Ann. Surg. 223: 94, 1996.
3. Cosimi, A. B., Conti, D., Delmonico, F. L., et al. In vivo effects of monoclonal antibody to ICAM in nonhuman primates with renal allografts. J. Immunol. 144: 4604, 1990.
4. Isobe, M., Yagita, H., Okumura, K., et al. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science 255: 1125, 1992.
5. Nathens, A. B., Bitar, R., Marshall, J. C., Dackiw, A. P. B., Watson, R. W. G., and Rotstein, O. D. Thiol-mediated regulation of endothelial ICAM-1 expression in acute lung injury. Surg. Forum. 47: 109, 1996.
6. Sayegh, M. H., Perico, N., Gallon, L., Imberti, O., Hancock, W. W., Remuzzi, G., and Carpenter, C. B. Mechanisms of acquired thymic unresponsiveness to renal allografts: Thymic recognition of immunodominant allo-MHC peptides induces peripheral T cell anergy. Transplantation 58: 125, 1994.
7. Jocelyn, P. C. Spectrophototemetric assay of thiols. Methods Enzymol. 143: 44, 1987.
8. Nathens, A. B., Marshall, J. C., Watson, R. W. G., Dackiw, A. P. B., and Rotstein, O. D. Diethylmaleate attenuates endotoxin-induced acute lung injury. Surgery 120: 360, 1996.
9. Gorczynski, R. M., Chan, Z., Chung, S., Cohen, Z., Levy, G., Sullivan, B., and Fu, X.-M. Prolongation of rat small bowel or renal allograft survival by pretransplant transfusion and/or by varying the route of allograft venous drainage. Transplantation 58: 816, 1994.
10. Chung, S. W., Gould, B., and Gorczynski, R. M. The role of ICAM-1 in the induction of antigen-specific T cell hyporesponsiveness. Immunol. Lett. 50: 155, 1996.
11. Gaber, L., Mann, L., Hughes, C., Kotb, M., Shokouh-Amiri, H., and Gaber, A. O. Patterns of expression of endothelial leukocyte adhesion molecules upon revascularization of transplanted kidneys in correlation with allograft pathology. Transplant. Proc. 1003, 1997.
12. Kooijmans-Coutinho, M. F., Bruijn, J. A., Hermans, J., Schindler, R., Frei, U., Schrama, E., van Es, L. A., Daha, M. R., and van der Woudde, F. J. Evaluation by histology, immunohistology and PCR of protocollized renal biopsies 1 week post transplant in relation to subsequent rejection episodes. Nephrol. Dial. Transplant. 10: 847, 1995.
13. Thervet, E., Patey, N., Legendre, C., Noel, L. H., and Kreis, H. Prospective evaluation of cell adhesion molecule expression in transplanted kidneys. Transplant. Proc. 27: 1007, 1995.
14. Mueller, D. L., Jenkins, M. K., and Schwartz, R. H. Clonal expansion versus functional clonal inactivation: a costimulatory singalling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 7: 445, 1989.
15. Sayegh, M. H., Akalin, E., Hancock, W. W., Russell, M. E., Carpenter, C. B., Linsley, P. S., and Turka, L. A. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J. Exp. Med. 181: 1869, 1995.
16. D'Elios, M. M., Josien, R., Manghetti, M., Amedeo, A., De Carli, M., Cuturi, M. C., Blancho, G., Buzelin, F., Del Prete, G., and Soulillou, J.-P. Predominant Th1 cell infiltration in acute rejection episodes of human kidney grafts. Kidney. Int. 51: 1876, 1997.
17. Kaminski, E. R., Kaminski, A., Bending, M. R., Chang, R., Heads, A., Szydlo, R. M., and Pereira, R. S. In vitro cytokine profiles and their relevance to rejection following renal transplantation. Transplantation 60: 703, 1995.
18. Kusaka, S., Grailer, A. P., Fechner, J. H., and Burlingham, W. J. Evidence for a possible Th2 bias in human renal transplant tolerance. Transplant. Proc. 27: 225, 1995.