Antitussive action of antihistamines is independent of sedative and ventilation activity in the guinea pig

Pharmacology

Volumn 57, Issue 2, 1998, Pages 57-64

  McLeod, Robbie L ^a   Mingo, Garfield ^a   O'Reilly, Sandra ^a   Ruck, LoriAnn ^a   Bolser, Donald C ^a   Hey, John A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Alkylamine; Antihistamine; Cough; Ethanolamine; Ethylenediamine; Phenothiazine; Piperazine; Piperidine; Sedation

Indexed keywords

ALIPHATIC AMINE; ANTIHISTAMINIC AGENT; ANTITUSSIVE AGENT; ASTEMIZOLE; CAPSAICIN; CETIRIZINE; CHLORPHENIRAMINE; CLEMASTINE; DIPHENHYDRAMINE; ETHANOLAMINE; ETHYLENEDIAMINE DERIVATIVE; HISTAMINE H1 RECEPTOR; HYDROXYZINE; MEPYRAMINE; PENTOBARBITAL; PHENOTHIAZINE; PIPERAZINE; PIPERIDINE DERIVATIVE; PROMETHAZINE; TERFENADINE; TRIPELENNAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING; CONTROLLED STUDY; COUGHING; GUINEA PIG; LUNG MINUTE VOLUME; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SEDATION;

ADMINISTRATION, ORAL; AMINES; ANIMALS; ANTITUSSIVE AGENTS; COUGH; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOLAMINES; ETHYLENEDIAMINES; GUINEA PIGS; HISTAMINE H1 ANTAGONISTS; HYPNOTICS AND SEDATIVES; MALE; PENTOBARBITAL; PHENOTHIAZINES; PIPERAZINES; PULMONARY VENTILATION; SLEEP; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031928099     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028226     Document Type: Article

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