Relationship of Bcl-2 expression with apoptosis and proliferation in colonic graft versus host disease

Human Pathology

Volumn 29, Issue 8, 1998, Pages 869-875

  Kraus, Madeleine D ^a   Shahsafaei, Aliakbar ^a   Antin, Joseph ^a   Odze, Robert D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Bone marrow transplant; CMV; Colitis; Diarrhea; Immunohistochemistry

Indexed keywords

PROTEIN BCL 2;

ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; COLON BIOPSY; COLON DISEASE; CONTROLLED STUDY; FEMALE; GRAFT VERSUS HOST REACTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

EID: 0031927615     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(98)90459-2     Document Type: Article

References (27)

1. Appleton AL, Sviland L: Current thoughts on the pathogenesis of graft versus host disease. J Clin Pathol 46:785-789, 1993
2. Ferrara JLM, Deeg HJ: Graft-versus-host disease. N Engl J Med 324:667-674, 1991
3. Bortin MM, Rimm AA: Treatment of 144 patients with severe aplastic anaemia using immunosuppression and allogeneic marrow transplantation: A report from the International Bone Marrow Transplantation Registry. Transplant Proc 13:227-229, 1981
4. Schiller GJ, Gale RP: A critical reappraisal of gastrointestinal complications of allogeneic bone marrow transplantation. Cell Transplant 1:265-269, 1992
5. Bombi JA, Nadal A, Carreras E, et al: Assessment of histopathologic changes in the colonic biopsy in acute graft-versus-host disease. Am J Clin Pathol 103:690-695, 1995
6. McDonald GB, Shulman HM, Sullivan KM, et al: Intestinal and hepatic complications of human bone marrow transplantation. Part 1. Gastroenterology 90:770-784, 1986
7. Ferrara JLM, Cooke KR, Pan L, et al: The immunopathophysiology of acute graft-versus-host disease. Stem Cells 14:473-489, 1996
8. Bombi JA, Palou J, Bruguera M, et al: Pathology of bone marrow transplantation. Semin Diagn Pathol 9:220-231, 1992
9. Sale GE, Shulman HM, McDonald GB, et al: Gastrointestinal graft-versus-host disease in man: A clinicopathologic study of the rectal biopsy. Am J Surg Pathol 3:291-299, 1979
10. Gilliam AC, Whitaker-Menezes D, Korngold R, et al: Apoptosis is the predominant form of epithelial target cell injury in acute experimental graft-versus-host disease. J Invest Dermatol 107:377-383, 1996
11. Que FG, Gores GJ: Cell death by apoptosis: Basic concepts and disease relevance for the gastroenterologist. Gastroenterology 110:1238-1243, 1996
12. Snover DC: Graft-versus-host disease of the gastrointestinal tract. Am J Surg Pathol 1:101-108, 1990 (suppl)
13. Majno G, Joris I: Apoptosis, oncosis, and necrosis: An overview of cell death. Am J Pathol 146:3-15, 1995
14. Sakai T, Kimura Y, Inagaki-Ohara K, et al: Fas-mediated cytotoxicity by intestinal intraepithelial lymphocytes during acute graft-versus-host disease in mice. Gastroenterology 113:168-174, 1997
15. Reed JC: Double identity for proteins of the Bcl-2 family-Nature 387:773-776, 1997
16. Tsujimoto Y, Croce CM: Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci USA 83:5214-5218, 1986
17. Hockenbery DM, Zutter M, Hickey W, et al: BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 88:6961-6965, 1991
18. Glucksberg H, Storb R, Fefer A, et al: Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA-matched sibling donors. Transplantation 18:295-304, 1974
19. Hall PA, Coates PJ, Ansair B, et al: Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis. J Cell Sci 107:3569-3577, 1994
20. Coles HSR, Burne JF, Raff MC: Large scale normal cell death in the developing rat kidneys and its reduction by epidermal growth factor. Development 118:777-784, 1993
21. Mapara MY, Bargou R, Zugck C, et al: APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: Correlation with bcl-2 oncogene expression. Eur J Immunol 23:702-708, 1993
22. Kernohan NM, Cox LS: Regulation of apoptosis by Bcl-2 and its related proteins: Immunochemical challenges and therapeutic implications. J Pathol 179:1-3, 1996
23. Averil MA: Fas and the immunologically underprivileged intestine. Gastroenterology 11:345-358, 1997
24. Kozopas KM, Yang T, Buchan HL, et al: MCL-1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2. Proc Natl Acad Sci USA 90:3516-3520, 1993
25. Hengartner MO, Horvitz HR: C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian protooncogene bcl-2. Cell 76:665-676, 1994
26. Miura M, Zhu H, Rotello R, et al: Induction of apoptosis in fibroblasts by IL-1 β-converting enzyme, a mammalian homologue of the C. elegans cell death gene ced-3. Cell 75:653-660, 1993
27. Merritt AJ, Potten CS, Watson AJM, et al: Differential expression of bcl-2 in intestinal epithelia: Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia. J Cell Sci 108:2261-2271, 1995