Influence of parasympathetic dysfunction and hyperinsulinemia on the hemodynamic response to an isometric exercise in non-insulin-dependent diabetic patients

Metabolism: Clinical and Experimental

Volumn 47, Issue 8, 1998, Pages 934-939

  Valensi, P ^a,b   Nguyen, T N ^a   Idriss, S ^a   Cazes, P ^a   Karam, G ^a   Paries, J ^a   Miossec, P ^a   Attali, J R ^a  

^a UNIVERSITÉ PARIS 13   (France)

^b HÔPITAL JEAN VERDIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ADRENERGIC SYSTEM; ADULT; ARTICLE; AUTONOMIC DYSFUNCTION; BLOOD PRESSURE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; FEMALE; HAND GRIP; HEART RATE; HEMODYNAMICS; HUMAN; HYPERINSULINEMIA; ISOMETRIC EXERCISE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL;

EID: 0031927487     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(98)90347-X     Document Type: Article

References (56)

1. Ewing DJ, Martyn CN, Young RJ, et al: The value of cardiovascular function tests: 10 years experience in diabetes. Diabetes Care 8:491-498, 1985
2. Valensi P, Attali JR, Sachs RN, et al: Intérêt comparé de l'enregistrement ECG des 24 heures et des manoeuvres standardisées dans la détection de la neuropathie autonome cardiaque chez le diabétique. Diabete Metab 13:205-209, 1987
3. Valensi P, Huart JP, Giroux C, et al: Factors involved in cardiac autonomic neuropathy in diabetic patients. J Diabet Compilc 11:180-187, 1997
4. Vanninnen E, Uusitupa M, Lansimies E, et al: Effect of metabolic control on autonomic function in obese patients with newly diagnosed type 2 diabetes. Diabetic Med 10:66-73, 1992
5. Bellavere F, Balzani I, De Masi G, et al: Power spectral analysis of heart rate variations improves assessment of diabetic cardiac autonomic neuropathy. Diabetes 41:633-640, 1992
6. Elghozi JL, Girard A, Laude D, et al: Spectral analysis of short term variability of blood pressure and pulse interval using finger blood pressure monitoring. Homeostasis 36:153-159, 1995
7. Blair DA, Glover WE, Roddie IC: Vasomotor fibres to skin in the upper arm, calf and thigh. J Physiol 153:232-238, 1960
8. Low PA, Neumann C, Dyck PJ, et al: Evaluation of skin vasomotor reflexes by using laser Doppler velocimetry. Mayo Clin Proc 58:583-592, 1983
9. Arnold RW, Dyer JA, Gould AB, et al: Sensitivity to vasovagal maneuvers in normal children and adults. Mayo Clin Proc 66:797-804, 1991
10. Gilmore JE, Allen JA, Hayes JR: A comparison of peripheral vasoconstrictor responses and cardiovascular autonomic function tests in diabetic patients. Diabetologia 33:350-356, 1990
11. Goldstein DS, Bonner RF, Zimlichman R, et al: Indices of sympathetic vascular innervation in sympathectomized patients. J Aut Nerv Syst 15:309-318, 1986
12. Oimoni M, Nishimoto S, Matsumoto S, et al: Evaluation of periflux blood flow measurement in diabetic patients with autonomic neuropathy. Diabetes Res Clin Pract 1:81-85, 1985
13. Valensi P, Smagghue O, Pariès J, et al: Peripheral vasoconstrictor responses to sympathetic activation in diabetic patients. Relationship with Theological disorders. Metabolism 46:235-241, 1997
14. Donald KW, Lind AR, McNicol GW, et al: Cardiovascular responses to sustained (static) contractions. Circ Res 20:15-30, 1967 (suppl 1)
15. Petrofsky JS, Lind AR: Ageing, isometric strength and endurance and cardiovascular responses to static effort. J Appl Physiol 38:91-95, 1975
16. Martin CE, Shaver JA, Leon DE, et al: Autonomic mechanisms in haemodynamic responses to isometric exercise. J Clin Invest 54:104-115, 1974
17. Hume L, Ewing DJ, Campbell IW, et al: Heart-rate response to sustained handgrip: Comparison of the effects of cardiac autonomic blockade and diabetic autonomic neuropathy. Clin Sci 56:287-291, 1979
18. Nazar K, Taton J, Chwalbinska-Moneta J, et al: Adrenergic responses to sustained handgrip in patients with juvenile onset-type diabetes mellitus. Clin Sci Mol Med 49:39-44, 1975
19. Hilsted J, Galbo H, Christensen NJ: Impaired cardiovascular responses to graded exercise in diabetic autonomic neuropathy. Diabetes 28:313-319, 1979
20. Hilsted J, Galbo H, Christensen NJ, et al: Haemodynamic changes during graded exercise in patients with diabetic autonomic neuropathy. Diabetologia 22:318-323, 1982
21. Kahn JK, Zola B, Juni JE, et al: Decreased exercise heart rate and blood pressure response in diabetic subjects with cardiac autonomic neuropathy. Diabetes Care 9:389-394, 1986
22. Roy TM, Peterson HR, Snider HL, et al: Autonomic influence on cardiovascular performance in diabetic subjects. Am J Med 87:382-388, 1989
23. Bottini P, Tantucci C, Scionti L, et al: Cardiovascular response to exercise in diabetic patients: Influence of autonomic neuropathy of different severity. Diabetologia 38:244-250, 1995
24. Ewing DJ, Irving JB, Kerr F, et al: Cardiovascular responses to sustained handgrip in normal subjects and in patients with diabetes mellitus: A test of autonomic function. Clin Sci Mol Med 46:295-306, 1974
25. Reaven GM: Role of insulin resistance in human disease. Diabetes 37:1595-1607, 1988
26. Ferrannini E, Buzzigoli G, Bonadonna R, et al: Insulin resistance in essential hypertension. N Engl J Med 317:350-357, 1987
27. Minh TH, Thanh MC, Bich Ngoc PT, et al: Insulin resistance and slight overweight: The case of vietnamese hypertensives. Int J Obes 21:897-902, 1997
28. Brands MW, Hildebrandt DA, Mizelle HL, et al: Sustained hyperinsulinemia increases arterial pressure in conscious rats. Am J Physiol 260:R764-R768, 1991
29. Gundersen HJG, Christensen NJ: Intravenous insulin causing loss of intravascular water and albumin and increased adrenergic nervous activity in diabetics. Diabetes 26:551-557, 1977
30. Liang C, Doherty JU, Faillace R, et al: Insulin infusion in conscious dogs: Effects on systemic and coronary hemodynamics, regional blood flows and plasma catecholamines. J Clin Invest 69:1321-1336, 1982
31. Rowe JW, Young JB, Minaker KL, et al: Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 30:219-225, 1981
32. Laakso M, Edelman SV, Brechtel G, et al: Decreased effect of insulin to stimulate skeletal blood flow in obese man: A novel mechanism for insulin resistance. J Clin Invest 85:1844-1852, 1990
33. Anderson EA, Hoffmann RP, Balon TW, et al: Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87:2246-2252, 1991
34. Ewing DJ, Campbell IW, Burt AA, et al: Vascular reflexes in diabetic autonomic neuropathy. Lancet 2:1354-1356, 1973
35. Valensi P: Neuropathie autonome cardiaque chez le diabétique. Méthodes de recherche et intérêt pratique. Diabete Metab 16:102-106, 1989
36. Valensi P, Phan Thi BN, Pariès J, et al: Cardiac autonomic function in obese patients. Int J Obes 19:113-118, 1995
37. Smith SE: AUTOCAFT. Lancet 2:772, 1988
38. Valensi P, Attali JR, Gagant S, et al: Reproducibility of parameters for assessment of diabetic neuropathy. Diabetic Med 10:933-939, 1993
39. Armstrong FM, Bradbury JE, Ellis SH, et al: A study of peripheral diabetic neuropathy. The implication of age-related reference values. Diabetic Med 8:S94-S99, 1991
40. Shamoon H, Friedman S, Canton C, et al: Increased epinephrine and skeletal muscle responses to hypoglycemia in non-insulin-dependent diabetes mellitus. J Clin Invest 93:2562-2571, 1994
41. Tack CJJ, Smits P, Willemsen JJ, et al: Effects of insulin on vascular tone and sympathetic nervous system in NIDDM. Diabetes 45:15-22, 1996
42. Ehrman J, Keteyian S, Fedel E, et al: Cardiovascular responses of heart transplant recipients to graded exercise testing. J Appl Physiol 73:260-264, 1992
43. Zarich SW, Arbuckle BE, Cohen LR, et al: Diastolic abnormalities in young asymptomatic diabetic patients assessed by pulse Doppler echocardiography. J Am Coll Cardiol 12:114-120, 1988
44. Attali JR, Sachs RN, Valensi P, et al: Asymptomatic diabetic cardiomyopathy: A non invasive study. Diabetes Res Clin Pract 4:183-190, 1988
45. Valensi P, Sachs RN, Lormeau B, et al: Silent myocardial ischemia and left ventricle hypertrophy in diabetic subjects. Diabetes Metab 23:409-416, 1997
46. Zola B, Kahn JK, Juni JE, et al: Abnormal cardiac function in diabetic patients with autonomic neuropathy in the absence of ischemic heart disease. J Clin Endocrinol Metab 63:208-214, 1986
47. Laakso M, Edelman SV, Brechtel G, et al: Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM. Diabetes 41:1076-1083, 1992
48. Baron AD, Laakso M, Brechtel G, et al: Reduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in non-insulin-dependent diabetic subjects: Effects of insulin therapy. J Clin Invest 87:1186-1194, 1991
49. Vollenweider P, Randin D, Tappy L, et al: Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humans. J Clin Invest 93:2365-2371, 1994
50. Dela F, Larsen JJ, Mikines KJ, et al: Normal effect of insulin to stimulate leg blood flow in NIDDM. Diabetes 44:221-226, 1995
51. Berne C, Fagius J, Pollare T, et al: The sympathetic response to euglycemic hyperinsulinaemia: Evidence from microelectrode nerve recordings in healthy subjects. Diabetologia 35:873-879, 1992
52. Hoffman RP, Sinkey CA, Kienzle MG, et al: Muscle sympathetic nerve activity is reduced in IDDM before overt autonomic neuropathy. Diabetes 42:375-380, 1993
53. Quadri R, Ponzani P, Zanone M, et al: Changes in autonomic nervous function over a 5-year period in non-insulin-dependent diabetic patients. Diabetes Med 10:916-919, 1993
54. Toyry JP, Niskanen LK, Mantysaari MJ, et al: Occurrence predictors and clinical significance of autonomic neuropathy in NIDDM. Ten-year follow-up from the diagnosis. Diabetes 45:308-315, 1996
55. Peterson HR, Rothschild M, Weinberg CR, et al: Body fat and the activity of the autonomic nervous system. N Engl J Med 318:1077-1083, 1988
56. Julius S: Sympathetic hyperactivity and coronary risk in hypertension. Hypertension 21:886-893, 1993