Moloney murine leukemia virus envelope protein subunits, gp70 and Pr15E, form a stable disulfide-linked complex

Journal of Virology

Volumn 72, Issue 8, 1998, Pages 6537-6545

  Opstelten, Dirk Jan E ^a   Wallin, Michael ^a   Garoff, Henrik ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS ENVELOPE PROTEIN GP 70; VIRUS ENVELOPE PROTEIN PR 15 E;

ANIMAL CELL; ARTICLE; CELL STRAIN BHK; DISULFIDE BOND; MOLONEY LEUKEMIA ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

EID: 0031927203     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.8.6537-6545.1998     Document Type: Article

References (56)

1. Barth, B. U., and H. Garoff. 1997. The nucleocapsid-binding spike subunit E2 of Semliki Forest virus requires complex formation with the E1 subunit for activity. J. Virol. 71:7857-7865.
2. Battini, J.-L., P. Rodrigues, R. Müller, O. Danos, and J. M. Heard. 1996. Receptor-binding properties of a purified fragment of the 4070A amphotropic murine leukemia virus envelope glycoprotein. J. Virol. 70:4387-4393.
3. Bedgood, R. M., and M. R. Stallcup. 1992. A novel intermediate in processing of murine leukemia virus envelope glycoprotein. J. Biol. Chem. 267:7060-7065.
4. Braakman, I., J. Helenius, and A. Helenius. 1992. Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum. EMBO J. 11:1717-1722.
5. Bullough, P. A., F. M. Hughson, J. J. Skehel, and D. C. Wiley. 1994. Structure of influenza hemagglutinin at the pH of membrane fusion. Nature 371:37-43.
6. Chan, D. C., D. Fass, J. M. Berger, and P. S. Kim. 1997. Core structure of gp41 from the HIV envelope protein. Cell 89:263-273.
7. Chivers, P. T., K. E. Prehoda, and R. T. Raines. 1997. The CXXC motif: a rheostat in the active site. Biochemistry 36:4061-4066.
8. Coffin, J. M. 1996. Retroviridae: the viruses and their replication, p. 1767-1847. In B. N. Fields, D. M. Knipe, P. M. Howley, et al. (ed.), Fields virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, Pa.
9. Evans, L. H., R. P. Morrison, F. G. Malik, J. Portis, and W. J. Britt. 1990. A neutralizable epitope common to the envelope glycoproteins of ecotropic, polytropic, xenotropic, and amphotropic murine leukemia viruses. J. Virol. 64:6176-6183.
10. Fass, D., and P. S. Kim. 1995. Dissection of a retrovirus envelope protein reveals structural similarity to influenza hemagglutinin. Curr. Biol. 5:1377-1383.
11. Fass, D., S. C. Harrison, and P. S. Kim. 1996. Retrovirus envelope domain at 1.7Å resolution. Nat. Struct. Biol. 3:465-469.
12. Fass, D., R. A. Davey, C. A. Hamson, P. S. Kim, J. M. Cunningham, and J. M. Berger. 1997. Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution. Science 277:1662-1666.
13. Freed, E. O., and R. Risser. 1987. The role of envelope glycoprotein processing in murine leukemia virus infection. J. Virol. 61:2852-2856.
14. Gliniak, B. C., S. L. Kozak, R. T. Jones, and D. Kabat. 1991. Disulfide bonding controls the processing of retroviral glycoproteins. J. Biol. Chem. 266:22991-22997.
15. Green, N., T. M. Shinnick, O. Witte, A. Ponticelli, J. G. Sutcliffe, and R. A. Lerner. 1981. Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptide. Proc. Natl. Acad. Sci. USA 78:6023-6027.
16. Gu, J., S. Parthasarathi, A. Varela-Echavarría, Y. Ron, and J. P. Dougherty. 1995. Mutations of conserved cysteine residues in the CWLC motif of the oncoretrovirus SU protein affect maturation and translocation. Virology 206:885-893.
17. Heard, J. M., and O. Danos. 1991. An amino-terminal fragment of Friend murine leukemia virus envelope glycoprotein binds the ecotropic receptor. J. Virol. 65:4026-4032.
18. Hughson, F. M. 1997. Enveloped viruses: a common mode of membrane fusion? Curr. Biol. 7:565-569.
19. Hunter, E., and R. Swanstrom. 1990. Retrovirus envelope glycoproteins. Curr. Top. Microbiol. Immunol. 157:187-253.
20. Hurtley, S. M., and A. Helenius. 1989. Protein oligomerization in the endoplasmic reticulum. Annu. Rev. Cell Biol. 5:277-307.
21. Hwang, C., A. J. Sinskey, and H. F. Lodish. 1992. Oxidized redox state of glutathione in the endoplasmic reticulum. Science 257:1496-1502.
22. Jones, J. S., and R. Risser. 1993. Cell fusion induced by the murine leukemia virus envelope glycoprotein. J. Virol. 67:67-74.
23. Kayman, S., R. Kopelman, D. Kiney, S. Projan, and A. Pinter. 1991. Mutational analysis of N-linked glycosylation sites of the Friend murine leukemia virus envelope proteins. J. Virol. 65:5323-5332.
24. Kitagawa, M., S. Aizawa, H. Kamisaku, H. Ikeda, K. Hirokawa, and T. Sado. 1995. Cell-free transmission of Fv-4 resistanec gene product controlling Friend leukemia virus-induced leukemogenesis: a unique mechanism for interference with viral infection. Blood 86:1557-1503.
25. Konishi, Y., T. Ooi, and H. A. Scheraga. 1982. Regeneration of ribonuclease A from the reduced protein. Rate-limiting steps. Biochemistry 21:4734-4740.
26. Kosower, N. S., and E. M. Kosower. 1995. Diamide: an oxidant probe for thiols. Methods Enzymol. 251:123-133.
27. Leamnson, R. N., M. H. M. Shander, and M. S. Halpern. 1977. A structural protein complex in Moloney leukemia virus. Virology 76:437-439.
28. Lebedeva, I., K. Fujita, A. Nihrane, and J. Silver. 1997. Infectious particles derived from Semliki Forest virus vectors encoding murine leukemia virus envelopes. J. Virol. 71:7061-7067.
29. Li, K.-J., and H. Garoff. 1996. Production of infectious recombinant Moloney murine leukemia virus particles in BHK cells using Semliki Forest virus-derived RNA expression vectors. Proc. Natl. Acad. Sci. USA 93:11658-11663.
30. Li, Z., A. Pinter, and S. C. Kayman. 1997. The critical N-linked glycan of murine leukemia virus envelope protein promotes both folding of the C-terminal domains of the precursor polyprotein and stability of the postcleavage envelope complex. J. Virol. 71:7012-7019.
31. Liyeström, P., and H. Garoff. 1991. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 9:1356-1361.
32. Linder, M., D. Linder, J. Hahnen, H.-H. Schott, and S. Stirm. 1992. Localization of the intrachain disulfide bonds of the envelope glycoprotein 71 from Friend murine leukemia virus. Eur. J. Biochem. 203:65-73.
33. Linder, M., V. Wenzel, D. Linder, and S. Stirm. 1994. Structural elements in glycoprotein 70 from polytropic Friend mink cell focus-inducing virus and glycoprotein 71 from ecotropic Friend murine leukemia virus, as defined by disulfide-bonding pattern and limited proteolysis. J. Virol. 68:5133-5141.
34. Machida, C. A., and D. Kabat. 1982. Role of partial proteolysis in processing murine leukemia virus membrane envelope glycoproteins to the cell surface. J. Biol. Chem. 257:14018-14022.
35. Nihrane, A., K. Fujita, R. Willey, M. S. Lyu, and J. Silver. 1996. Murine leukemia virus envelope protein in transgenic-mouse serum blocks infection in vitro. J. Virol. 70:1882-1889.
36. Nihrane, A., I. Lebedeva, M. S. Lyu, K. Fujita, and J. Silver. 1997. Secretion of a murine retroviral Env associated with resistance to infection. J. Gen. Virol. 78:785-793.
37. Opstelten, D.-J. E., P. de Groote, M. C. Horzinek, H. Vennema, and P. J. M. Rottier. 1993. Disulfide bonds in folding and transport of mouse hepatitis coronavirus glycoproteins. J. Virol. 67:7394-7401.
38. Oroszlan, S., and R. B. Luftig. 1990. Retroviral proteinases. Curr. Top. Microbiol. Immunol. 157:153-185.
39. Ott, D., R. Friedrich, and A. Rein. 1990. Sequence analysis of amphotropic and 10A1 murine leukemia viruses: close relationship to mink cell focus-inducing viruses. J. Virol. 64:757-766.
40. Pinter, A., and E. Fleissner. 1977. The presence of disulfide-linked gp70-p15E complexes in AKR murine leukemia virus. Virology 83:417-422.
41. Pinter, A., J. Lieman-Hurwitz, and E. Fleissner. 1978. The nature of the association between the murine leukemia virus envelope proteins. Virology 91:345-351.
42. Pinter, A., R. Kopelman, Z. Li, S. C. Kayman, and D. A. Sanders. 1997. Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol-disulfide exchange enzymes. J. Virol. 71:8073-8077.
43. Sattentau, Q. J., and J. P. Moore. 1991. Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding. J. Exp. Med. 174:407-415.
44. Schneider, J., and G. Hunsmann. 1978. Surface expression of murine leukemia virus structural polypeptides on host cells and the virion. Int. J. Cancer 22:204-213.
45. Schneider, J., H. Falk, and G. Hunsmann. 1980. Envelope polypeptides of Friend leukemia virus: purification and structural analysis. J. Virol. 33:597-605.
46. Schultz, A. M., and A. Rein. 1985. Maturation of murine leukemia virus env proteins in the absence of other viral proteins. Virology 145:335-339.
47. Sitbon, M., L. d'Auriol, H. Ellerbrok, C. André, J. Nishio, S. Perryman, F. Pozo, S. F. Hayes, K. Wehrly, P. Tambourin, F. Galibert, and B. Chesebro. 1991. Substitution of leucine for isoleucine in a sequence highly conserved among retroviral envelope surface glycoproteins attenuates the lytic effect of the Friend murine leukemia virus. Proc. Natl. Acad. Sci. USA 88:5932-5936.
48. Stamatatos, L., and C. Cheng-Mayer. 1995. Structural modulations of the envelope gp120 glycoprotein of human immunodeficiency virus type 1 upon oligomerizalion and differential V3 loop epitope exposure of isolates displaying distinct tropism upon viriori-soluble receptor binding. J. Virol. 69: 6191-6198.
49. Suomalainen, M., and H. Garoff. 1994. Incorporation of homologous and heterologous proteins into the envelope of Moloney murine leukemia virus. J. Virol. 68:4879-4889.
50. Suomalainen, M., K. Hultenby, and H. Garoff. 1996. Targeting of Moloney murine leukemia virus Gag precursor to the site of virus budding. J. Cell Biol. 135:1841-1852.
51. Takemoto, L. J., C. F. Fox, F. C. Jensen, J. H. Elder, and R. A. Lerner. 1978. Nearest-neighbor interactions of the major RNA tumor virus glycoprotein on murine cell surfaces. Proc. Natl. Acad. Sci. USA 75:3644-3648.
52. Thomas, A., and M. J. Roth. 1995. Analysis of cysteine mutations on the transmembrane protein of Moloney murine leukemia virus. Virology 211:285-289.
53. Thomas, A., K. D. Gray, and M. J. Roth. 1997. Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane protein. Virology 227:305-313.
54. Weissenhorn, W., A. Dessen, S. C. Harrison, J. J. Skehel, and D. C. Wiley. 1997. Atomic structure of the ectodomain from HIV-1 gp41. Nature (London) 387:426-430.
55. Weissman, J. S., and P. S. Kim. 1992. The pro region of BPTI facilitates folding. Cell 71:841-851.
56. Witte, O. N., A. Tsukaraoto-Adey, and I. L. Weissman. 1977. Cellular maturation of oncornavirus glycoproteins: topological arrangement of precursor and product forms in cellular membranes. Virology 76:539-553.