Incidence of exacerbations in the first 90 days of treatment with recombinant human interferon β-1b in patients with relapsing-remitting multiple sclerosis

Annals of Neurology

Volumn 44, Issue 1, 1998, Pages 138-139

  Khan, Omar A ^a,b   Hebel, J Richard ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CORTICOSTEROID; METHYLPREDNISOLONE; PREDNISONE;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RELAPSE; RETROSPECTIVE STUDY; STATISTICAL ANALYSIS; TREATMENT INDICATION; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; CASE-CONTROL STUDIES; FEMALE; GLUCOCORTICOIDS; HUMANS; INCIDENCE; INJECTIONS, INTRAVENOUS; INTERFERON-BETA; MALE; METHYLPREDNISOLONE; MIDDLE AGED; MULTIPLE SCLEROSIS; NERVOUS SYSTEM DISEASES; NEUROPROTECTIVE AGENTS; PREDNISONE; RECOMBINANT PROTEINS; RECURRENCE; RETROSPECTIVE STUDIES;

EID: 0031927091     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410440123     Document Type: Article

References (5)

1. The IFNβ Multiple Sclerosis Study Group. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebocontrolled trial. Neurology 1993;43:655-661
2. Noronha A, Toscas A, Jensen MA. Interferon β decreases T cell activation and interferon γ production in multiple sclerosis. J Neuroimmunol 1993;46:145-153
3. Panitch HS, Hirsch RL, Haley AS, Johnson KP. Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1987; 1:893-895
4. Dayal AS, Jensen MA, Lledo A, Arnason BGW. Interferongamma-secreting cells in multiple sclerosis patients treated with interferon beta-lb. Neurology 1995;45:2173-2177
5. Trotter JL, Garvey WF. Prolonged effects of large-dose methylprednisolone infusion in multiple sclerosis. Neurology 1980;30: 702-708