Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin-B receptors. II

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 6, 1998, Pages 951-961

  Takeda, Yasuyuki ^a   Kawagoe, Keiichi ^a   Yokomizo, Aki ^a   Yokomizo, Yoshihiro ^a   Hosokami, Toru ^a   Shimoto, Yoshimasa ^a   Tabuchi, Yoshiaki ^a   Ogihara, Yoshiyasu ^a   Otsubo, Rira ^a   Honda, Yuko ^a   Yokohama, Shuichi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

DA 3934; Gastric acid secretion; Gastrin cholecystokinin B receptor antagonist; Phenoxyacetic acid; Structure activity relationship; Ureido phenylacetic acid

Indexed keywords

1 [2,3 DIHYDRO 1 (2' METHYLPHENACYL) 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL] 3 (3 METHYLPHENYL)UREA; 2 [3 [3 [N [2 (N METHYL N PHENYLCARBAMOYLMETHOXY)PHENYL] N (N METHYL N PHENYLCARBAMOYLMETHYL)CARBAMOYLMETHYL]UREIDO]PHENYL]ACETIC ACID; CHOLECYSTOKININ B RECEPTOR; GASTRIN RECEPTOR; PHENOXYACETIC ACID DERIVATIVE; PROGLUMIDE; UNCLASSIFIED DRUG;

ARTICLE; DOSE RESPONSE; RECEPTOR BINDING; RECEPTOR POTENTIAL; STOMACH ACID SECRETION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 0031926763     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.951     Document Type: Article

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