Human lung cancer cell lines express cell membrane complement inhibitory proteins and are extremely resistant to complement-mediated lysis; a comparison with normal human respiratory epithelium in vitro, and an insight into mechanism(s) of resistance

Clinical and Experimental Immunology

Volumn 113, Issue 2, 1998, Pages 173-182

  Varsano, S ^a,b,d   Rashkovsky, L ^b   Shapiro, H ^c   Ophir, D ^d,e   Mark Bentankur, T ^d,e  

^a Department of Pulmonary Medicine ^*

^b Lab of Respiratory Cell Biology

^c Laboratory of Haematology   (Netherlands)

^d MEIR MEDICAL CENTER   (Israel)

^e TEL AVIV UNIVERSITY   (Israel)

Author keywords

CD46; CD55; CD59; Complement inactivators; Lung cancer cell lines; Nasal epithelium; Phosphatidylinositol specific phospholipase C

Indexed keywords

CD59 ANTIGEN; DECAY ACCELERATING FACTOR; MEMBRANE COFACTOR PROTEIN; PHOSPHOLIPASE C;

ARTICLE; CANCER RESISTANCE; CANCER SUSCEPTIBILITY; COMPLEMENT ACTIVATION; COMPLEMENT INHIBITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM;

ANTIGENS, CD; ANTIGENS, CD46; ANTIGENS, CD55; ANTIGENS, CD59; CARCINOMA, NON-SMALL-CELL LUNG; CELL MEMBRANE; COMPLEMENT ACTIVATION; COMPLEMENT INACTIVATOR PROTEINS; EPITHELIAL CELLS; HUMANS; LUNG NEOPLASMS; MEMBRANE GLYCOPROTEINS; NASAL MUCOSA; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PHOSPHOLIPASE C; TUMOR CELLS, CULTURED;

EID: 0031926467     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00581.x     Document Type: Article

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