Attempted suicide with azathioprine in a boy with juvenile chronic polyarthritis;Azathioprin-ingestion in suizidaler absicht bei einem jugendlichen mit juveniler chronischer polyarthritis

Klinische Padiatrie

Volumn 210, Issue 3, 1998, Pages 136-138

  Krüger, Carsten ^a,b   Jüngert, Jörg ^a   Schmitt Grohe, Sabina ^a   Beese, Maike ^a   Ruder, Hans ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Acute toxicity; Azathioprine; Leukopenia; Puberty; Suicide attempt

Indexed keywords

AZATHIOPRINE; CHARCOAL; IPECAC; METHOTREXATE;

ADOLESCENT; ARTICLE; CASE REPORT; DRUG OVERDOSE; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LEUKOCYTE COUNT; MALE; SUICIDE ATTEMPT; THROMBOCYTE COUNT; VOMITING;

EID: 0031926359     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1043866     Document Type: Article

References (23)

1. Arnold, M. H., J. O'Callaghan, M. McCredie, E. M. Beller, D. E. Kelly, P. M. Brooks: Comparative controlled trial of low-dose weekly methotrexate versus azathioprine in rheumatoid arthritis: 3-year prospective study. Br. J. Rheumatol. 29 (1990) 120-125
2. Berlit, P.: Azathioprin. Pädiat. Prax. 49 (1995) 533-538
3. Brendel, W., U. Hopf: Autoimmunerkrankungen, Klinik und Therapie. Schattauer, Stuttgart-New York 1968, p 95
4. Burroughs Wellcome & Co (USA), Inc.: Azathioprine (Imuran) 50 mg scored tablets: An adjunct for the prevention of rejection in renal homotransplantation. Clin. Pharmacol. Ther. 10 (1969) 136-141
5. Calabresi, P., R. E. Parks jr.: Antiproliferative agents and drugs used for immunosuppression. In: Gilman, A. G., L. S. Goodman, T. W. Rall, F. Murad (Hrsg.), The pharmacological basis of therapeutics, 7th ed. Macmillan Publishing Company, New York 1985, pp 1276-1277
6. Carney, D. M., C. F. Zukoski, D. A. Ogden: Massive azathioprine overdose. Case report and review of the literature. Am. J. Med. 56 (1974) 133-136
7. Connell, W. R., M. A. Kamm, M. Dickson, A. M. Balkwill, J. K. Ritchie: Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. Lancet 343 (1994) 1249-1252
8. Dorr, R. T., W. L. Fritz: Cancer Chemotherapy Handbook. Elsevier, New York 1980, pp 246-250, 513-518
9. Elion, G. B., S. Callahan, S. Bieber, G. H. Hitchings, R. W. Rundles: A summary of investigations with 6-(1-methyl-4-nitro-5-imidazolyl)-thio purine (B. W. 57-332). Cancer Chemother. Rep. 14 (1961) 93-98
10. Elion, G. B.: Biochemistry and pharmacology of purine analogues. Fed. Proc. 26 (1967) 898-904
11. Elion, G. B., G. H. Hitchings: Azathioprine. In: Sartorelli, B. A. C., D. G. Johns (Hrsg.), Handbook of experimental pharmacology, Vol. 38. Springer, New York 1975. pp 404-425
12. Isomäki, H., T. Hakulinen, U. Joutsenlahti: Lymphoma and rheumatoid arthritis. Lancet I (1979) 392-394
13. Kinlen, L. J.: Incidence of cancer in rheumatoid arthritis and other disorders after immunsuppressive treatment. Am. J. Med 78 (Suppl. 1A) (1985) 44-49
14. Krieger, G., P. Keller, J. Schirmeister: 1st Azathioprin (Imurek) onkogen? Krankenhausarzt 53 (1980) 321-322
15. Laine, J., C. Holmberg, K. Salmela, H. Jalanko, H. Sairanen, K. Peltola, K. Ronnholm, B. Eklund, S. Wikstrom, M. Leijala: Renal transplantation in children with emphasis on young patients. Pediatr. Nephrol. 8 (1994) 313-319
16. Lawson, D. H., G. E. Lovatt, C. S. Gurton, R. C. Hennings: Adverse effects of azathioprine. Adverse Drug React. Acute Poisoning Rev. 3 (1984) 161-171
17. Midence, K.: The effects of chronic illness on children and their families: an overview. Genet. Soc. Gen. Psychol. Monogr. 120 (1994) 311-326
18. Neuhaus T. J., J. Fay, M. J. Dillon, R. S. Trompeter, T. M. Barratt: Alternative treatment to corticosteroids in steroid sensitive idiopathic nephrotic syndrome. Arch. Dis. Child. 71 (1994) 522-526
19. Schröder, J. O., U. M. Schwab, A. Schnabel, F. Asbeck, K. -H. Zurborn, W. L. Gross, H. H. Euler: Häufung MTX-assoziierter Zytopenien bei älteren Patienten. Dt. Ärztebl. 93 (1996) A 321-322
20. Schusziarra, V., V. Ziekursch, R. Schlamp, H. C. Siemensen: Pharmacokinetics of azathioprine under haemodialysis. Int. J. Clin. Pharmacol. Biopharm. 14 (1976) 298-302
21. ten-Berge, R. J., P. T. Schellekens, S. Surachno, T. H. The, J. H. ten-Veen, J. M. Wilmink: The influence of therapy with azathioprine and prednisone on the immune system of kidney transplant recipients. Immunopathol. 21 (1981) 20-32
22. Wilson, W. P., S. A. Benezra: Azathioprine. In: Florey, K. (Hrsg.), Analytical profiles of drug substances, Vol. 10. Academic Press, New York 1981, pp 29-53
23. Zylber-Katz, E., C. Putterman, Y. Caraco: Multiple drug overdose in a kidney transplant patient. Ther. Drug. Monit. 16 (1994) 327-331