Antagonist effect of insulin-like growth factor I on protein kinase inhibitor-mediated apoptosis in human glioblastoma cells in association with bcl-2 and bcl-X(L)

Journal of Neurosurgery

Volumn 88, Issue 5, 1998, Pages 884-889

  Toms, Steven A ^a   Hercbergs, Aleck ^a   Liu, Jinbo ^a   Kondo, Seiji ^a   Haqqi, Talat ^a   Casey, Graham ^a   Iwasaki, Koichi ^a   Barnett, Gene H ^a   Barna, Barbara P ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b METROHEALTH MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Glioblastoma multiforme; Insulin like growth factor I; Tamoxifen

Indexed keywords

PROTEIN BCL 2; PROTEIN KINASE INHIBITOR; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TAMOXIFEN;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GLIOBLASTOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

EID: 0031925325     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1998.88.5.0884     Document Type: Article

References (27)

1. Casey G, Lo-Hsueh M, Lopez ME, et al: Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene. Oncogene 6:1791-1797, 1991
2. Casey G, Yamanaka Y, Friess H, et al: P53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis. Cancer Lett 69:151-160, 1993
3. Couldwell WT, Antel JP, Apuzzo MLJ, et al: Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system. J Neurosurg 73:594-600, 1990
4. Couldwell WT, Hinton, DR, He S, et al: Protein kinase C inhibitors induce apoptosis in human malignant glioma cell lines. FEBS Lett 345:43-46, 1994
5. Couldwell WT, Uhm JH, Antel JP, et al: Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro. Neurosurgery 29:880-887, 1991
6. Couldwell WT, Weiss MH, DeGiorgio CM, et al: Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen. Neurosurgery 32:485-490, 1993
7. Dunn SE, Hardman RA, Kari FW, et al: Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anti-cancer drugs. Cancer Res 57:2687-2693, 1997
8. Favoni RE, de Cupis A, Ravera F, et al: Expression and function of the insulin-like growth factor 1 system in human non-small-cell lung cancer and normal lung cell lines. Int J Cancer 56:858-866, 1994
9. Galli C, Meucci O, Scorziello A, et al: Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J Neurosci 15: 1172-1179, 1995
10. Gammeltoft S, Ballotti R, Kowalski A, et al: Expression of two types of receptor for insulin-like growth factors in human malignant glioma. Cancer Res 48:1233-1237, 1988
11. Huynh HT, Tetenes E, Wallace L, et al: In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen. Cancer Res 53:1727-1730, 1993
12. Iwasaki K, Toms SA, Barnett GH, et al: Inhibitory effects of tamoxifen and tumor necrosis factor alpha on human glioblastoma cells. Cancer Immunol Immunother 40:228-234, 1995
13. Kern SE, Pietenpol JA, Thiagalingam S, et al: Oncogenic forms of p53 inhibit p53-regulated gene expression. Science 256: 827-830, 1992
14. Kuerbitz SJ, Plunkett BS, Walsh WV, et al: Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA 89:7941-7945, 1992
15. Lønning PE, Hall K, Aakvaag A, et al: Influence of tamoxifen on plasma levels of insulin-like growth factor 1 and insulin like growth factor binding protein 1 in breast cancer patients. Cancer Res 52:4719-4723, 1992
16. Lowe WL Jr, Meyer T, Karpen CW, et al: Regulation of insulin-like growth factor 1 production in rat C6 glioma cells: possible role as an autocrine/paracrine growth factor. Endocrinology 130:2683-2391, 1992
17. Miyashita T, Krajewski S, Krajewska M, et al: Tumor suppressor p53 is a regulator of bcl-2 and box gene expression in vitro and in vivo. Oncogene 9:1799-1805, 1994
18. Muta K, Krantz SB, Bondurant MC, et al: Distinct roles of erythroprotein, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells. J Clin Invest 94:34-43, 1994
19. Oberhammer F, Wilson JW, Dive C, et al: Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12:3679-3684, 1993
20. Parrizas M, LeRoith D: Insulin-like growth factor-1 inhibition of apoptosis is associated with increased expression of the bcl-xL gene product. Endocrinology 138:1355-1358, 1997
21. Pavlovič-Surjancev B, Cahill AL, Perlman RL: Nicotinic agonists, phorbol esters, and growth factors activate two extracellular signal-related kinases, ERK1 and ERK2, in bovine chromaffin cells. J Neurochem 59:2134-2140, 1992
22. Pollack IF, Randall MS, Kristofik MP, et al: Effect of tamoxifen on DNA synthesis and proliferation of human malignant glioma lines in vitro. Cancer Res 50:7134-7138, 1990
23. Pollack IF, Randall MS, Kristofik MP, et al: Response of malignant glioma cell lines to activation and inhibition of protein kinase C-mediated pathways. J Neurosurg 73:98-105, 1990
24. Sandberg-Nordqvist AC, Ståhlbom PA, Reinecke M, et al: Characterization of insulin-like growth factor 1 in human primary brain tumors. Cancer Res 53:2475-2478, 1993
25. Sell C, Baserga R, Rubin R: Insulin-like growth factor 1 (IGF-1) and the IGF-1 receptor prevent etoposide-induced apoptosis. Cancer Res 55:303-306, 1995
26. Somers KD, Merrick MA, Lopez ME, et al: Frequent p53 mutations in head and neck cancer. Cancer Res 52:5997-6000, 1992
27. Van Meir EG, Kikuchi T, Tada M, et al: Analysis of the p53 gene and its expression in human glioblastoma cells. Cancer Res 54:649-652, 1994